Caterina M Gallippi

Works (49)

Updated: April 5th, 2024 05:27

2023 journal article

Comparing Focused-Tracked and Plane Wave-Tracked ARFI Log(VoA) In Silico and in Application to Human Carotid Atherosclerotic Plaque, Ex Vivo

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 70(7), 636–652.

author keywords: Acoustic radiation force impulse (ARFI) imaging; atherosclerosis; carotid; elastography; plane wave; plaque characterization; variance of acceleration (VoA)
MeSH headings : Humans; Plaque, Atherosclerotic / diagnostic imaging; Plaque, Atherosclerotic / pathology; Carotid Stenosis / pathology; Carotid Arteries / diagnostic imaging; Carotid Arteries / pathology; Atherosclerosis; Elasticity Imaging Techniques / methods
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 7, 2023

2022 article

4D Cardiac Gated Vector Flow Imaging Accurately Measures WSS in a Pressurized Closed-Loop System

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: K. Anand n & C. Gallippi n

author keywords: wall shear stress; WSS; plane wave; 4D; vector flow
TL;DR: The results demonstrate that, despite the poor elevational resolution of a linear array, volumetric WSS can be measured throughout the cardiac cycle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 6, 2023

2022 article

Breast Lesion Diameter in VisR Imaging Differs Between Malignant and Benign Masses in Women

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: A. Phillips n, G. Torres n, D. Steed*, M. Caughey n, J. Merhout*, S. Kirk*, T. Hartman*, C. Kuzmiak*, E. Ray*, C. Gallippi n

author keywords: Acoustic Radiation Force; ARFI; Viscoelastic Response; VisR; Elastography; Breast Cancer; Benign; Malignant; E/B Ratio; Strain Elastography
TL;DR: It is found that E/B ratio measured from VisR relative elasticity (RE) and relative viscosity (RV) statistically separated benign and malignant breast lesions and improved AUC and sensitivity compared to E/Bs measured from ARFI peak displacement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: February 6, 2023

2022 article

Combined B-mode and Nakagami Images for Improved Discrimination of Breast Masses using Deep Learning

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: S. Muhtadi n, S. Haque* & C. Gallippi n

author keywords: breast cancer; ultrasound imaging; quantitative ultrasound; nakagami imaging; deep learning
TL;DR: It is hypothesized that combining the images, which contain complementary information, will provide better classification performance in a deep learning framework than using the images by themselves, and its potential to provide improved diagnosis for breast cancer is demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 6, 2023

2022 article

Concurrent ARFI Plaque Imaging and Wall Shear Stress Measurement in Human Carotid Artery, with Validation by Fluid Structure Interaction Models

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: K. Anand n, E. Kolahdouz*, J. Homeister*, M. Smith*, B. Griffith* & C. Gallippi n

author keywords: plane wave; vector flow; ARFI; VoA; WSS; FSI; simulation
TL;DR: The results demonstrate the feasibility of concurrent imaging of carotid plaque composition by ARFI VoA, vector flow, and WSS to better assess stroke risk. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 6, 2023

2022 article

Development of a Robotic Shear Wave Elastography System for Noninvasive Staging of Liver Disease in Murine Models

Czernuszewicz, T. J., Aji, A. M., Moore, C. J., Montgomery, S. A., Velasco, B., Torres, G., … Gessner, R. C. (2022, February 24). HEPATOLOGY COMMUNICATIONS.

By: T. Czernuszewicz n, A. Aji*, C. Moore*, S. Montgomery*, B. Velasco n, G. Torres n, K. Anand n, K. Johnson n ...

MeSH headings : Animals; Disease Models, Animal; Elasticity Imaging Techniques / methods; Female; Liver Cirrhosis / diagnostic imaging; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease / diagnostic imaging; Reproducibility of Results; Robotic Surgical Procedures
TL;DR: Robotic SWE in small animals is feasible and sensitive to small changes in liver disease state, facilitating in vivo staging of rodent liver disease with minimal sonographic expertise. (via Semantic Scholar)
Source: Web Of Science
Added: March 7, 2022

2022 journal article

Quantitative Estimation of Mechanical Anisotropy Using Acoustic Radiation Force (ARF)-Induced Peak Displacements (PD): In Silico and Experimental Demonstration

IEEE TRANSACTIONS ON MEDICAL IMAGING, 41(6), 1468–1481.

By: M. Hossain n & C. Gallippi n

author keywords: Anisotropy; ARFI; ultrasound elastography; shear wave; muscle; kidney
MeSH headings : Acoustics; Animals; Anisotropy; Cross-Sectional Studies; Elastic Modulus; Elasticity Imaging Techniques / methods; Swine
TL;DR: The feasibility of using the ARFI PD to quantify elastic DoA in biological tissues is demonstrated, using a model empirically derived from Field II and finite element method (FEM) simulations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 20, 2022

2022 article

Quantitative Estimation of Shear Elastic Heterogeneity and Anisotropy in Excised Canine Kidneys using Double Profile Intersection (DoPIo) Ultrasound

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: K. Yokoyama n, T. Nichols* & C. Gallippi n

author keywords: ARFI; Elastography; DoPIo; Beamforming; Heterogeneity; Anisotropy; Kidney
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 6, 2023

2022 article

Quantitative Viscoelastic Response (QVisR) Domain Adaption with Fine Tuning

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: J. Richardson n & C. Gallippi n

author keywords: Acoustic Radiation Force (ARF); Viscoelastic Response (VisR); Quantitative Viscoelastic Response (QVisR); Viscoelasticity; Elastography; Machine Learning
TL;DR: This work fine-tunes QVisR models with scanner data acquired in a CIRS elasticity phantom to adapt the modulus estimation domain from simulation to phantom, suggesting fine tuning can be used to adapt simulation trained Q VisR models to more realistic imaging environments with a small, labeled dataset. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 6, 2023

2022 article

in vivo VisR Measurements of Viscoelasticity and Viscoelastic Anisotropy in Human Allografted Kidneys Differentiate Interstitial Fibrosis and Graft Rejection

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: K. Yokoyama n, M. Hossain n, M. Caughey n, M. Fisher*, R. Detweiler*, E. Chang*, C. Gallippi n

author keywords: ARFI; Elastography; VisR; Beamforming; Anisotropy; Viscoelasticity; Fibrosis; Inflammation
TL;DR: Viscoelastic Response imaging is relevant to early detection of transplant kidney fibrosis and rejection, which could enable timely interventions that extend graft life, and noninvasive VisR RE-based RR had similar performance but also differentiated rejected from fibrotic kidney. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: February 6, 2023

2021 journal article

A 1.5-D Array for Acoustic Radiation Force (ARF)-Induced Peak Displacement-Based Tissue Anisotropy Assessment With a Row-Column Excitation Method

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(4), 1278–1287.

By: H. Wu n, M. Hossain n, H. Kim n, C. Gallippi n & X. Jiang n

author keywords: Transducers; Flexible printed circuits; Acoustics; Fabrication; Impedance; Anisotropic magnetoresistance; Muscles; 15-D array; acoustic radio forced impulse (ARFI); anisotropy; fractional anisotropy; peak displacement (PD); row-column excitation
MeSH headings : Acoustics; Anisotropy; Mechanical Phenomena; Phantoms, Imaging; Transducers
TL;DR: The results suggest that the array is capable of assessing DoA using PD ratio without physical rotation of the transducer and has the potential to reduce the misalignment errors for DoA assessment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 27, 2021

2021 article

ARFI Variance of Acceleration for Diagnostic Breast Cancer Imaging in Women, in vivo

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

By: A. Phillips n, G. Torres n, D. Steed*, M. Caughey n, J. Merhout*, S. Kirk*, T. Hartman*, C. Kuzmiak*, E. Ray*, C. Gallippi n

author keywords: Acoustic Radiation Force (ARF); Variance of Acceleration (VoA); Elastography; Breast Cancer; Benign; Malignant; Fluid-filled; Necrosis; Solid
TL;DR: A new metric, ΔLog(VoA), which can be calculated from ARFI ultrasound data and incorporates the mechanical and acoustic properties of tissue into one parameter is proposed, which can differentiate clinically relevant lesion features such as fluid and necrosis, and detect tissue characteristics that coincide with malignancy. (via Semantic Scholar)
Source: Web Of Science
Added: August 15, 2022

2021 article

Assessing the Impact of ARF Excitation Beam Width and Tracking Beam Concurrency on DoPIo Imaging Performance in a Calibrated Phantom

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

By: K. Yokoyama n, K. Anand n & C. Gallippi n

author keywords: ARFI; Elastography; DoPIo; Speckle Tracking; PSF; Beamforming; Displacement Underestimation
TL;DR: In silico experiments suggested that DoPIo acquisitions performed using a wide ARF push beam and simultaneous tracking provided the most accurate and precise elasticity estimates, while all four combinations of parameters enabled the differentiation of a soft inclusion within a stiff background in vitro. (via Semantic Scholar)
Source: Web Of Science
Added: August 15, 2022

2021 article

Atherosclerotic Plaque Characterization in Humans with ARFI Variance of Acceleration: Blinded Reader Study

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

By: G. Torres n, M. Caughey n, K. Anand n, B. Huang n, E. Lee n, C. Zamora n, S. Hung n, E. Merricks n ...

author keywords: ARFI imaging; carotid plaque
TL;DR: This study shows the relevance of ARFI log(VoA) imaging, as interpreted by trained, blinded readers, to delineating the structure and composition of carotid atherosclerotic plaque in humans, in vivo. (via Semantic Scholar)
Source: Web Of Science
Added: August 15, 2022

2021 article

Automatic Classification of Human Carotid Plaque Features, In Vivo, Using Multiple Forms of ARFI Data

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

author keywords: ARFI imaging; carotid plaque
TL;DR: Results suggest that using multiple forms of frequency and gating of ARFI data as inputs to an automatic classifier improves discrimination of carotid plaque components, relevant for rupture vulnerability assessment. (via Semantic Scholar)
Source: Web Of Science
Added: August 15, 2022

2021 article

Effect of SNR on Quantitative Viscoelastic Response (QVisR) Ultrasound in silico

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

By: J. Richardson n & C. Gallippi n

author keywords: Acoustic Radiation Force (ARF); Viscoelastic Response (VisR); Quantitative Viscoelastic Response (QVisR); Viscoelasticity; Elastography; Machine Learning
Source: Web Of Science
Added: August 15, 2022

2021 journal article

Electronic Point Spread Function Rotation Using a Three-Row Transducer for ARFI-Based Elastic Anisotropy Assessment: In Silico and Experimental Demonstration

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(3), 632–646.

By: M. Hossain* & C. Gallippi n

author keywords: Transducers; Finite element analysis; Mechanical factors; Acoustics; Muscles; Anisotropic magnetoresistance; Direction-of-arrival estimation; Acoustic radiation force impulse (ARFI); anisotropy; muscle; peak displacement (PD); shear wave elasticity imaging (SWEI); transversely isotropic (TI) material
MeSH headings : Animals; Anisotropy; Computer Simulation; Elasticity Imaging Techniques; Electronics; Reproducibility of Results; Rotation; Swine; Transducers
TL;DR: Evaluated results suggest that ARFI-based DoA assessment can be achieved without manual transducer rotation using a three-row transducers capable of electronically rotating PSFs by 63°. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 5, 2021

2021 article

Multiangle PW Compounding Supports ARFI Variance of Acceleration (VoA) Carotid Plaque Imaging for Integration with Vector Doppler

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

By: K. Anand n & C. Gallippi n

author keywords: ARFI; atherosclerosis; coherent compounding; plane wave; variance of acceleration; vascular
TL;DR: Compared to an unsteered PW sequence, a multi-angle compounded PW sequence improves log(VoA) performance, suggesting the potential for extension to implementation with concurrent vector Doppler imaging. (via Semantic Scholar)
Source: Web Of Science
Added: August 15, 2022

2020 journal article

Carotid Plaque Fibrous Cap Thickness Measurement by ARFI Variance of Acceleration: In Vivo Human Results

IEEE TRANSACTIONS ON MEDICAL IMAGING, 39(12), 4383–4390.

author keywords: Thickness measurement; Imaging; In vivo; Image segmentation; Acceleration; Atherosclerosis; Correlation; Atherosclerosis; carotid endarterectomy (CEA); carotid plaque; acoustic radiation force impulse (ARFI) imaging
MeSH headings : Acceleration; Atherosclerosis; Carotid Arteries / diagnostic imaging; Carotid Stenosis / diagnostic imaging; Endarterectomy, Carotid; Humans; Plaque, Atherosclerotic / diagnostic imaging
TL;DR: It is suggested that ARFI log(VoA) enables improved discrimination of fibrous cap thickness relative to ARFI PD and further contributes to the growing body of evidence demonstrating ARFI’s overall relevance to delineating the structure and composition of carotid atherosclerotic plaque for stroke risk prediction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 4, 2021

2020 journal article

Viscoelastic Response Ultrasound Derived Relative Elasticity and Relative Viscosity Reflect True Elasticity and Viscosity: In Silico and Experimental Demonstration

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 67(6), 1102–1117.

By: M. Hossain n & C. Gallippi n

author keywords: Acoustic radiation force impulse (ARFI); mass-spring-damper (MSD); shear wave dispersion ultrasound vibrometry (SDUV); shear wave elasticity; ultrasound; viscoelastic response (VisR) ultrasound; viscoelasticity
MeSH headings : Animals; Computer Simulation; Dogs; Elasticity / physiology; Elasticity Imaging Techniques / methods; Image Processing, Computer-Assisted / methods; Liver / diagnostic imaging; Liver / physiology; Phantoms, Imaging; Viscosity
TL;DR: The hypothesis that RE and RV linearly correlate to true elasticity and viscosity in tissue is tested and results suggest thatRE and RV are relevant for qualitatively assessing the elastic and viscous properties of tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 22, 2020

2019 journal article

Delineation of Human Carotid Plaque Features In Vivo by Exploiting Displacement Variance

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 66(3), 481–492.

By: G. Torres n, T. Czernuszewicz n, J. Homeister*, M. Caughey*, B. Huang*, E. Lee*, C. Zamora*, M. Farber* ...

author keywords: Acoustic radiation force impulse (ARFI) imaging; atherosclerosis; carotid endarterectomy (CEA); carotid plaque characterization
MeSH headings : Aged; Carotid Arteries / diagnostic imaging; Carotid Arteries / pathology; Carotid Arteries / surgery; Carotid Stenosis / diagnostic imaging; Carotid Stenosis / pathology; Carotid Stenosis / surgery; Elasticity Imaging Techniques / methods; Endarterectomy, Carotid; Female; Humans; Image Interpretation, Computer-Assisted / methods; Male; Middle Aged; Plaque, Atherosclerotic / diagnostic imaging; Plaque, Atherosclerotic / pathology; Plaque, Atherosclerotic / surgery; Signal-To-Noise Ratio
TL;DR: It is suggested that log(VoA) enhances the differentiation of LRNC, IPH, COL, and CAL in human carotid plaques, in vivo, which is clinically relevant to improving stroke risk prediction and medical management. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: April 2, 2019

2019 journal article

Mechanical Anisotropy Assessment in Kidney Cortex Using ARFI Peak Displacement: Preclinical Validation and Pilot In Vivo Clinical Results in Kidney Allografts

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 66(3), 551–562.

By: M. Hossain n, R. Detwiler*, E. Chang*, M. Caughey*, M. Fisher*, T. Nichols*, E. Merricks*, R. Raymer* ...

author keywords: Acoustic radiation force impulse (ARFI); anisotropy; chronic kidney disease (CKD); kidney transplant; renal rejection; shear wave elasticity imaging (SWEI); ultrasound
MeSH headings : Adult; Aged; Allografts / diagnostic imaging; Allografts / physiology; Animals; Anisotropy; Elastic Modulus / physiology; Elasticity Imaging Techniques / methods; Female; Humans; Kidney Cortex / diagnostic imaging; Kidney Cortex / physiology; Kidney Transplantation; Male; Middle Aged; Renal Insufficiency, Chronic / diagnostic imaging; Renal Insufficiency, Chronic / surgery; Swine
TL;DR: The results of this pilot clinical study suggest the feasibility of implementing symmetrical ARF to obviate mechanical anisotropy in the kidney cortex when anisOTropy is a confounding factor and implementing asymmetric ARF in the cortex of human kidney allografts to exploit mechanical an isotropy when mechanicalAnisotropic biomarker is a potentially relevant biomarker. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 2, 2019

2019 article

On the Quantitative Potential of Viscoelastic Response (VisR) Ultrasound Using the One-Dimensional Mass-Spring-Damper Model (vol 63, pg 1276, 2016)

Selzo, M. R., Moore, C. J., Hossain, M. M., Palmeri, M. L., & Gallippi, C. M. (2019, January). IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, Vol. 66, pp. 251–251.

By: M. Selzo n, C. Moore n, M. Hossain n, M. Palmeri* & C. Gallippi n

TL;DR: In the original publication of this paper, equation (3) contained sign errors for the amplitude of the third and fourth Heaviside functions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 18, 2019

2019 article

On the feasibility of quantifying mechanical anisotropy in transversely isotropic elastic materials using acoustic radiation force (ARF)-induced displacements

MEDICAL IMAGING 2019: ULTRASONIC IMAGING AND TOMOGRAPHY, Vol. 10955.

By: M. Hossain n & C. Gallippi n

author keywords: Anisotropy; ARFI; SWEI; Transversely isotropic model; Muscle; Kidney; Peak displacement
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 1, 2019

2019 article

Special Issue on Pilot Clinical Translation of New Medical Ultrasound Methodologies

Gallippi, C. M., & Dahl, J. J. (2019, March). IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, Vol. 66, pp. 423–424.

By: C. Gallippi n & J. Dahl*

TL;DR: A vital first step to translating these cutting-edge ultrasound methods to clinical implementation is performing pilot studies in humans, in vivo, to demonstrate the feasibility of new methodologies in the context of complex tissue environments with unknown parameters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 2, 2019

2018 journal article

Blind Source Separation-Based Motion Detector for Imaging Super-Paramagnetic Iron Oxide (SPIO) Particles in Magnetomotive Ultrasound Imaging

IEEE TRANSACTIONS ON MEDICAL IMAGING, 37(10), 2356–2366.

By: M. Hossain n, B. Levy*, D. Thapa*, A. Oldenburg* & C. Gallippi n

author keywords: Blind source separation (BSS); principal component analysis (PCA); motion detection; MMUS imaging; nanoparticles
MeSH headings : Algorithms; Equipment Design; Magnetite Nanoparticles / chemistry; Phantoms, Imaging; Principal Component Analysis; Ultrasonography / instrumentation; Ultrasonography / methods
TL;DR: A novel blind source separation-based FPL (BSS-FPL) algorithm is presented for detecting motion using a shorter ensemble length (EL) than FPL and without <inline-formula>, which is an important step toward translating MMUS imaging to <italic>in vivo</italic>, where long tracking ensembles would increase acquisition time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 19, 2018

2018 journal article

EVALUATING RENAL TRANSPLANT STATUS USING VISCOELASTIC RESPONSE (VISR) ULTRASOUND

ULTRASOUND IN MEDICINE AND BIOLOGY, 44(8), 1573–1584.

By: M. Hossain n, M. Selzo*, R. Hinson*, L. Baggesen*, R. Detwiler*, W. Chong*, L. Burke*, M. Caughey* ...

author keywords: Kidney transplant; Renal rejection; Chronic kidney disease; Viscoelastic response (VisR); Viscoelasticity; Acoustic radiation force impulse; Ultrasound
MeSH headings : Adult; Elasticity; Elasticity Imaging Techniques / methods; Female; Humans; Image Processing, Computer-Assisted / methods; Kidney / diagnostic imaging; Kidney Transplantation; Male; Middle Aged; Postoperative Complications / diagnostic imaging; Prospective Studies; Viscosity
TL;DR: It is suggested that allografts with scarring and vascular disease can be identified using non-invasive VisR RE and RV metrics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2018 journal article

IN VIVO VISCOELASTIC RESPONSE (VISR) ULTRASOUND FOR CHARACTERIZING MECHANICAL ANISOTROPY IN LOWER-LIMB SKELETAL MUSCLES OF BOYS WITH AND WITHOUT DUCHENNE MUSCULAR DYSTROPHY

ULTRASOUND IN MEDICINE AND BIOLOGY, 44(12), 2519–2530.

By: C. Moore n, M. Caughey*, D. Meyer*, R. Emmett*, C. Jacobs*, M. Chopra*, J. Howard*, C. Gallippi n

author keywords: Viscoelastic response (VisR) ultrasound; Acoustic radiation force; Duchenne muscular dystrophy; Viscoelasticity; Anisotropy; Transverse isotropy
TL;DR: The results suggest that Viscoelastic Response RE and RV measures reflect differences in mechanical anisotropy associated with functional impairment with dystrophic degeneration that are relevant to monitoring DMD clinically. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: November 19, 2018

2017 conference paper

ARFI variance of acceleration (VoA) for noninvasive characterization of human carotid plaques in vivo

Proceedings of annual international conference of the ieee engineering, 2984–2987.

MeSH headings : Carotid Arteries; Carotid Stenosis; Hemorrhage; Humans; Necrosis; Plaque, Atherosclerotic; Ultrasonography
TL;DR: A new ARFI-based measurement, the variance of acceleration (VoA), is evaluated for differentiating among soft and stiff plaque components, and results were obtained in vivo for a human carotid plaque acquired in a previous study and matched to a histological standard analyzed by a pathologist. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Acoustic Radiation Force Impulse-Induced Peak Displacements Reflect Degree of Anisotropy in Transversely Isotropic Elastic Materials

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 64(6), 989–1001.

By: M. Hossain n, C. Moore n & C. Gallippi n

author keywords: Anisotropy; ARFI; fractional anisotropy; peak displacement; strain; transversely isotropic material
TL;DR: The results support that symmetrical ARFI focal configurations are desirable when the orientation of the ARFI excitation to the AoS is not specifically known and measurement standardization is important, such as for longitudinal or cross-sectional studies of anisotropic organs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Performance of acoustic radiation force impulse ultrasound imaging for carotid plaque characterization with histologic validation

JOURNAL OF VASCULAR SURGERY, 66(6), 1749-+.

By: T. Czernuszewicz n, J. Homeister*, M. Caughey*, Y. Wang*, H. Zhu*, B. Huang*, E. Lee*, C. Zamora* ...

MeSH headings : Aged; Area Under Curve; Calcium / analysis; Carotid Arteries / chemistry; Carotid Arteries / diagnostic imaging; Carotid Arteries / pathology; Carotid Artery Diseases / diagnostic imaging; Carotid Artery Diseases / pathology; Collagen / analysis; Elasticity Imaging Techniques; Female; Fibrosis; Hemorrhage / diagnostic imaging; Hemorrhage / pathology; Humans; Male; Middle Aged; Necrosis; Observer Variation; Pilot Projects; Plaque, Atherosclerotic; Predictive Value of Tests; Prognosis; Prospective Studies; ROC Curve; Reproducibility of Results; Vascular Calcification / diagnostic imaging; Vascular Calcification / pathology
TL;DR: The performance of acoustic radiation force impulse (ARFI) imaging, a noninvasive ultrasound elasticity imaging method, for delineating the composition of human carotid plaque in vivo with histologic validation is suggested to be capable of distinguishing soft from stiff atherosclerotic plaque components and delineating FC thickness. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Thrombin-responsive transcutaneous patch for auto-anticoagulant regulation

Advanced Materials, 29(4).

By: Y. Zhang n, J. Yu n, J. Wang n, N. Hanne n, Z. Cui n, C. Qian n, C. Wang n, H. Xin n ...

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2016 conference paper

Carotid plaque characterization with ARFI imaging: Blinded reader study

2016 ieee international ultrasonics symposium (ius).

By: T. Czernuszewicz*, J. Homeister*, M. Caughey n, B. Huang*, E. Lee*, C. Zamora*, M. Farber*, J. Fulton* ...

TL;DR: It is suggested that ARFI is capable of distinguishing soft from stiff compositional elements of atherosclerotic plaques and may be relevant to improving plaque risk assessment. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2016 conference paper

Cross-sectional comparison of in vivo viscoelastic response (VisR) ultrasound in lower limb muscles of boys with and without Duchenne muscular dystrophy

2016 ieee international ultrasonics symposium (ius).

By: C. Moore n, M. Selzo, M. Caughey, D. Meyer*, R. Emmett*, J. Howard*, M. Chopra*, C. Gallippi n

TL;DR: VisR results were consistent with temporally-matched functional testing using a hand-held dynamometer, and suggest that VisR imaging is relevant to delineating viscoelastic property alterations that are associated with dystrophic muscle degeneration in boys with DMD, in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Design, Fabrication, and Characterization of a Bifrequency Colinear Array

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 63(2), 266–274.

By: Z. Wang n, S. Li n, T. Czernuszewicz n, C. Gallippi n, R. Liu*, X. Geng*, X. Jiang n

author keywords: Bifrequency ultrasound; colinear array; composite transducer
TL;DR: The results of this study suggest that bifrequency colinear arrays are potential aids for wideband fundamental imaging and harmonic/subharmonic imaging. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

On the Feasibility of Quantifying Fibrous Cap Thickness With Acoustic Radiation Force Impulse (ARFI) Ultrasound

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 63(9), 1262–1275.

By: T. Czernuszewicz n & C. Gallippi n

author keywords: Acoustic radiation force; acoustic radiation force impulse (ARFI); atherosclerosis; fibrous cap (FC); finite-element method (FEM); resolution; vulnerable plaque
MeSH headings : Carotid Arteries / diagnostic imaging; Elasticity Imaging Techniques; Humans; Motion; Plaque, Atherosclerotic / diagnostic imaging; Ultrasonography
TL;DR: The results of this study demonstrate that tracking pulse frequencies around 12 MHz are necessary to resolve caps around 0.2 mm; large motion-tracking kernel sizes introduce bias into thickness measurements and overestimate the true cap thickness; and color saturation settings on ARFI peak displacement images can impact thickness measurement accuracy substantially. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

On the Quantitative Potential of Viscoelastic Response (VisR) Ultrasound Using the One-Dimensional Mass-Spring-Damper Model

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 63(9), 1276–1287.

By: M. Selzo n, C. Moore n, M. Hossain n, M. Palmeri* & C. Gallippi n

author keywords: Acoustic radiation force (ARF); mass spring damper (MSD); viscoelasticity; viscoelastic response (VisR) ultrasound
MeSH headings : Acoustics; Elastic Modulus; Humans; Mechanical Phenomena; Ultrasonography; Viscosity
TL;DR: The results suggest VisR's potential relevance to quantifying viscoelastic properties clinically and suggest the feasibility of corrected VisR imaging in vivo in the rectus femoris muscle of an adult with no known neuromuscular disorders is suggested. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 conference paper

On the quantitative potential of viscoelastic response (VisR) ultrasound using matrix array transducers: In silico demonstration

2016 ieee international ultrasonics symposium (ius).

By: M. Hossain*, C. Moore n & C. Gallippi n

Source: NC State University Libraries
Added: August 6, 2018

2015 article

Dual-frequency IVUS transducer for acoustic radiation force impulse (ARFI) imaging

2015 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS).

By: Z. Wang n, X. Jiang n, T. Czernuszewicz* & C. Gallippi*

author keywords: dual frequency ultrasound; ultrasound transducer; intravascular ultrasound; IVUS; acoustic radiation force; ARFI
TL;DR: A dual-frequency IVUS transducer, consisting of a 6.5 MHz “pushing” element and a 26 MHz ‘tracking’ element, was designed and fabricated for ARFI application and suggests great potential of this dual- frequencies for intravascular ARFI imaging. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

NON-INVASIVE IN VIVO CHARACTERIZATION OF HUMAN CAROTID PLAQUES WITH ACOUSTIC RADIATION FORCE IMPULSE ULTRASOUND: COMPARISON WITH HISTOLOGY AFTER ENDARTERECTOMY

ULTRASOUND IN MEDICINE AND BIOLOGY, 41(3), 685–697.

By: T. Czernuszewicz n, J. Homeister*, M. Caughey*, M. Farber*, J. Fulton*, P. Ford*, W. Marston*, R. Vallabhaneni*, T. Nichols*, C. Gallippi n

author keywords: Atherosclerosis; Stroke; Plaque characterization; Carotid endarterectomy; Acoustic radiation force impulse; Ultrasound
MeSH headings : Aged; Carotid Artery, Internal / diagnostic imaging; Carotid Stenosis / diagnostic imaging; Carotid Stenosis / surgery; Elasticity Imaging Techniques / methods; Endarterectomy, Carotid; Female; Humans; Male; Middle Aged; Plaque, Atherosclerotic / diagnostic imaging; Predictive Value of Tests; Risk Assessment; Risk Factors; Stroke / prevention & control; Treatment Outcome
TL;DR: In this preliminary study, in vivo ARFI imaging is presented in a case study format for four patients undergoing clinically indicated carotid endarterectomy and compared with histology, illustrating the feasibility and challenges of transcutaneous ARFI for characterizing the material and structural composition of carotids atherosclerotic plaques via mechanical properties, in humans, in vitro. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 article

Viscoelastic Response (VisR) Assessment of Longitudinal Dystrophic Degeneration in Clinical Duchenne Muscular Dystrophy

2015 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS).

By: C. Moore n, M. Selzo*, M. Caughey, D. Meyer*, R. Emmett*, J. Howard*, M. Chopra, C. Gallippi n

author keywords: Viscoelastic Response (VisR); Duchenne Muscular Dystrophy; Viscoelasticity; Muscle
TL;DR: Results suggest that VisR, a noninvasive ultrasound imaging method, may be clinically viable for monitoring local muscular compositional and structural changes associated with dystrophic degeneration, in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 article

Acoustic radiation force (ARF) generation with a novel dual-frequency intravascular transducer.

2014 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), pp. 2284–2287.

By: T. Czernuszcwicz, C. Gallippi n, Z. Wang n, J. Ma* & X. Jiang n

author keywords: ultrasound transducer; dual frequency; acoustic radiation force; ARFI; intravascular; IVUS
TL;DR: The results of this study show that ARF generation and high-resolution tracking is feasible on a small-aperture transducer fit for IVUS implementation, and is also shown to demonstrate backscatter sensitivity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 article

Displacement Underestimation Correction Using Shear Waves in VisR Ultrasound

2014 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), pp. 1065–1068.

By: M. Selzo*, T. Czernuszewicz* & C. Gallippi n

author keywords: Viscoelastic Response (VisR) ultrasound; Acoustic Radiation Force (ARF); finite element model; optical tracking
TL;DR: It is hypothesized that by utilizing shear waves to generate displacement and monitoring tissue displacement outside the region of excitation the authors can better estimate axial displacements and generate τ measurements that more closely represent the material. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 article

Distinguishing Viscous from Elastic Properties in Viscoelastic Response (VisR) Ultrasound

2014 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), pp. 1117–1120.

By: M. Selzo* & C. Gallippi n

author keywords: Viscoelastic Response (VisR) ultrasound; Acoustic Radiation Force (ARF); elasticity; viscosity; mass-spring-damper model; finite element model
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 article

In Vivo ARFI Surveillance of Subcutaneous Hemorrhage (ASSH) for Monitoring rcFVIII Dose Response in Hemophilia A Dogs

2014 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), pp. 2296–2299.

author keywords: Acoustic Radiation Force Impulse (ARFI) ultrasound; Hemophilia A; canine; dog model; subcutaneous hemorrhage; bleeding
TL;DR: There was a significant difference (p<;0.05, Wilcoxon ranksum) in ASSH bleeding rate (BR) and a 34.8% reduction in occurrence of abnormal ASSH time to hemostasis (TTH) between naive hemophilia A and hemophili A treated to 100% rcFVIII cohorts, indicating that ASSH could be relevant in differentiating bleeding responses to different levels of rcF VIII treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Acoustic Radiation Force Beam Sequence Performance for Detection and Material Characterization of Atherosclerotic Plaques: Preclinical, Ex Vivo Results

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 60(12), 2471–2487.

By: R. Behler n, T. Czernuszewicz n, C. Wu*, T. Nichols*, H. Zhu*, J. Homeister*, E. Merricks*, C. Gallippi n

MeSH headings : Algorithms; Animals; Elasticity Imaging Techniques / methods; Femoral Artery / diagnostic imaging; Femoral Artery / pathology; Image Processing, Computer-Assisted; Phantoms, Imaging; Plaque, Atherosclerotic / diagnostic imaging; ROC Curve; Swine
TL;DR: Results suggest ARF-based imaging is relevant to detecting and characterizing plaques and support its use for diagnosing and monitoring atherosclerosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Experimental Validation of Displacement Underestimation in ARFI Ultrasound

ULTRASONIC IMAGING, 35(3), 196–213.

By: T. Czernuszewicz n, J. Streeter n, P. Dayton n & C. Gallippi n

author keywords: acoustic radiation force; ARFI; optical tracking; differential motion decorrelation; shearing artifact; displacement underestimation
MeSH headings : Acoustics; Elasticity; Elasticity Imaging Techniques / standards; Image Processing, Computer-Assisted / methods; Microspheres; Motion; Phantoms, Imaging; Reproducibility of Results; Ultrasonics / methods
TL;DR: Optical tracking was utilized to experimentally measure the displacement underestimation achieved by acoustic tracking using a clinical ultrasound system and sets up a framework for future displacement tracking validation studies. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

ARFI IMAGING FOR NONINVASIVE MATERIAL CHARACTERIZATION OF ATHEROSCLEROSIS PART II: TOWARD IN VIVO CHARACTERIZATION

ULTRASOUND IN MEDICINE AND BIOLOGY, 35(2), 278–295.

By: R. Behler n, T. Nichols*, H. Zhu*, E. Merricks* & C. Gallippi n

author keywords: Acoustic radiation force; Ultrasound; Atherosclerosis; Detection; Characterization; Collagen; Elastin; Pig model
MeSH headings : Acoustics; Algorithms; Animals; Atherosclerosis / diagnostic imaging; Collagen / analysis; Elastin / analysis; Iliac Artery / diagnostic imaging; Image Interpretation, Computer-Assisted / methods; Immunohistochemistry; Models, Animal; Swine; Ultrasonography
TL;DR: Acoustic radiation force impulse (ARFI) ultrasound, a novel imaging method for noninvasively differentiating the mechanical properties of tissue, is demonstrated for in vivo detection of nonstenotic plaques and plaque material assessment in this pilot investigation, validates the potential relevance of ARFI imaging as a noninvasive imaging technology for in vitro detection and material assessment of atherosclerotic plaque. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Robust principal component analysis and clustering methods for automated classification of tissue response to ARFI excitation

ULTRASOUND IN MEDICINE AND BIOLOGY, 34(2), 309–325.

By: F. Mauldin n, H. Zhu*, R. Behler n, T. Nichols* & C. Gallippi n

author keywords: acoustic radiation force impulse ultrasound; automatic classification; atherosclerosis; robust principal component analysis; robust K-means clustering
MeSH headings : Acoustics; Algorithms; Animals; Computer Simulation; Iliac Artery / diagnostic imaging; Iliac Artery / metabolism; Image Interpretation, Computer-Assisted / methods; Immunohistochemistry; Principal Component Analysis; Swine; Ultrasonography
TL;DR: This work suggests that automatic identification of tissue structures exhibiting similar displacement responses to ARFI excitation is possible, even in the context of outlier profiles, and represents an important first step toward automatic correlation of ARFI data to spatially matched immunohistochemistry. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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