Christopher M. McLaughlin

Works (2)

Updated: March 7th, 2024 05:00

2023 journal article

Delayed-release rapamycin halts progression of left ventricular hypertrophy in subclinical feline hypertrophic results of the RAPACAT trial

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 261(11), 1628–1637.

By: J. Kaplan *, V. Rivas n , A. Walker*, L. Grubb, A. Farrell, S. Fitzgerald, S. Kennedy, C. Pjauregui ...

Contributors: J. Kaplan *, V. Rivas n , A. Walker*, L. Grubb, A. Farrell, S. Fitzgerald, S. Kennedy, C. Pjauregui ...

author keywords: HCM; sirolimus; occult; cat; mTOR
TL;DR: It is demonstrated that DR rapamycin was well tolerated and may prevent or delay progressive LV hypertrophy in cats with subclinical HCM and no demographic, echocardiographic, or clinicopathologic values were significantly different between study groups at baseline, confirming successful randomization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 6, 2024

2016 journal article

Thromboelastographic monitoring of the effect of unfractionated heparin in healthy dogs

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 27(1), 71–81.

By: C. McLaughlin n, S. Marks n, D. Dorman n, A. Motsinger-Reif n & R. Hanel n

author keywords: anticoagulation monitoring; anti-Xa; canine; RapidTEG; thrombosis
MeSH headings : Animals; Anticoagulants / administration & dosage; Anticoagulants / pharmacology; Blood Coagulation / drug effects; Dogs; Female; Heparin / administration & dosage; Heparin / pharmacology; Injections, Subcutaneous / veterinary; Male; Partial Thromboplastin Time / veterinary; Prospective Studies; Reference Values; Thrombelastography / veterinary
TL;DR: This study demonstrates that TEG variables derived using robust activation correlate with AXa activity as well as aPTT and have the potential to be used for monitoring UFH therapy in healthy dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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