Works (9)

Updated: July 5th, 2023 15:41

2017 journal article

The Porphobilinogen Conundrum in Prebiotic Routes to Tetrapyrrole Macrocycles

ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES, 47(1), 93–119.

By: M. Taniguchi n, M. Ptaszek*, V. Chandrashaker n & J. Lindsey n

Contributors: M. Taniguchi n, M. Ptaszek*, V. Chandrashaker n & J. Lindsey n

author keywords: delta-aminolevulinic acid; Porphyrinogen; Porphyrin; DFT; Biosynthesis; Biomimetic
MeSH headings : Aminolevulinic Acid / analogs & derivatives; Aminolevulinic Acid / chemistry; Evolution, Chemical; Kinetics; Origin of Life; Porphobilinogen / chemistry; Tetrapyrroles / chemistry
TL;DR: The results suggest efforts toward a biomimetic, enzyme-free route to tetrapyrroles from ALA should turn away from structure-directed reactions and focus on catalysts that orient the two aminoketones to form PBG in a kinetically controlled process, thereby avoiding formation of pseudo-PBG. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Bioconjugatable, PEGylated hydroporphyrins for photochemistry and photomedicine. Narrow-band, red-emitting chlorins

NEW JOURNAL OF CHEMISTRY, 40(9), 7721–7740.

By: M. Liu n, C. Chen n, A. Mandal*, V. Chandrashaker n, R. Evans-Storms*, J. Pitner*, D. Bocian*, D. Holten*, J. Lindsey n

TL;DR: Three molecular designs have been developed wherein stable synthetic chlorins - analogues of chlorophylls - have been tailored with PEG groups for use in aqueous solution, augur well for development of a set of spectrally distinct chlorins with relatively sharp bands in the red region. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Complexity in structure-directed prebiotic chemistry. Reaction bifurcation from a beta-diketone in tetrapyrrole formation

NEW JOURNAL OF CHEMISTRY, 40(7), 6434–6440.

By: R. Deans n, M. Taniguchi n, V. Chandrashaker n, M. Ptaszek n & J. Lindsey n

Contributors: R. Deans n, M. Taniguchi n, V. Chandrashaker n, M. Ptaszek n & J. Lindsey n

Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Complexity in structure-directed prebiotic chemistry. Unexpected compositional richness from competing reactants in tetrapyrrole formation

NEW JOURNAL OF CHEMISTRY, 40(7), 6421–6433.

By: R. Deans n, M. Taniguchi n, V. Chandrashaker n, M. Ptaszek n, D. Chambers n, A. Soares n, J. Lindsey n

Contributors: R. Deans n, M. Taniguchi n, V. Chandrashaker n, M. Ptaszek n, D. Chambers n, A. Soares n, J. Lindsey n

Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Scope and limitations of two model prebiotic routes to tetrapyrrole macrocycles

NEW JOURNAL OF CHEMISTRY, 40(9), 7445–7455.

By: M. Taniguchi n, R. Deans n, V. Chandrashaker n, M. Ptaszek n & J. Lindsey n

Contributors: M. Taniguchi n, R. Deans n, V. Chandrashaker n, M. Ptaszek n & J. Lindsey n

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Synthesis of diverse acyclic precursors to pyrroles for studies of prebiotic routes to tetrapyrrole macrocycles

NEW JOURNAL OF CHEMISTRY, 40(10), 8786–8808.

By: V. Chandrashaker n, M. Ptaszek n, M. Taniguchi n & J. Lindsey n

Contributors: V. Chandrashaker n, M. Ptaszek n, M. Taniguchi n & J. Lindsey n

TL;DR: The synthesis of 53 compounds is described, encompassing 28 new compounds as well as 25 known compounds that have been more fully characterized or prepared via alternative routes that may prove useful in mainstream syntheses of diverse tetrapyrroles regardless of possible prebiotic relevance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

Complexity in structure-directed prebiotic chemistry. Effect of a defective competing reactant in tetrapyrrole formation

NEW JOURNAL OF CHEMISTRY, 39(11), 8273–8281.

By: R. Deans n, V. Chandrashaker n, M. Taniguchi n & J. Lindsey n

Contributors: R. Deans n, V. Chandrashaker n, M. Taniguchi n & J. Lindsey n

Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

Progress towards synthetic chlorins with graded polarity, conjugatable substituents, and wavelength tunability

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 19(4), 547–572.

By: D. Ra n, K. Gauger n, K. Muthukumaran n, T. Balasubramanian n, V. Chandrashaker n, M. Taniguchi n, Z. Yu*, D. Talley* ...

Contributors: D. Ra n, K. Gauger n, K. Muthukumaran n, T. Balasubramanian n, V. Chandrashaker n, M. Taniguchi n, Z. Yu*, D. Talley* ...

author keywords: auxochrome; artificial photosynthesis; chlorophyll; hydroporphyrin; hydrophilic; photomedicine
TL;DR: Twenty new chlorins (17 targets, 6 intermediates) have been prepared and the challenge associated with molecular designs that encompass the combination of "hydrophilic, bioconjugatable and wavelength-tunable" chiefly resides in the nature of the hydrophilic unit. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Panchromatic absorbers for solar light-harvesting

CHEMICAL COMMUNICATIONS, 50(93), 14512–14515.

By: E. Alexy n, J. Yuen*, V. Chandrashaker n, J. Diers*, C. Kirmaier*, D. Bocian*, D. Holten*, J. Lindsey n

TL;DR: A set of panchromatic absorbers exhibiting long excited-state lifetimes in both polar and nonpolar media has been prepared and should find utility in molecular solar-conversion systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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