Works (94)
Updated: June 16th, 2024 05:04
2024 journal article
Transcriptome profile of pecan scab resistant and susceptible trees from a pecan provenance collection
BMC GENOMICS, 25(1).
author keywords: Pecan; Scab; RNA-seq; DEG; Fungal resistance; Venturia; Carya; Provenance
TL;DR:
The results provide the first account of candidate genes involved in resistance/susceptibility to pecan scab under natural conditions in a pecan orchard and can be used to aid pecan breeding programs and development of biotechnology-based approaches for generating pecan cultivars with more durable scab resistance.
(via Semantic Scholar)
bmcgenomics.biomedcentral.com (publisher PDF)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024
2023 article
Fescue Toxicosis: Understanding the Fungal Cause and the Fungal Solution
Young, C. A. (2023, May). JOURNAL OF ANIMAL SCIENCE, Vol. 101.
TL;DR:
Dr. Young will share research on utilizing genomic techniques to better understand the various endophyte species in forage grazing systems.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024
2022 journal article
Cross-species transcriptomics identifies core regulatory changes differentiating the asymptomatic asexual and virulent sexual life cycles of grass-symbiotic Epichloë fungi
G3.
Ed(s): J. Dunlap
author keywords: Epichloe; stroma; mutalism; virulence; plant-fungal interactions; RNAseq
MeSH headings : Animals; Epichloe / genetics; Life Cycle Stages; Poaceae / genetics; Symbiosis / genetics; Transcriptome
TL;DR:
A comparative analysis of 26 Epichloë genomes found a general decrease in core differentially expressed gene conservation among asexual species, and a specific decrease in conservation for the biosynthetic gene cluster expressed during virulent growth and an unusual uncharacterized gene.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2022 journal article
Population Genetic Characteristics and Mating Type Frequency of Venturia effusa from Pecan in South America
Phytopathology®.
MeSH headings : Ascomycota / genetics; Brazil; Carya / genetics; Carya / microbiology; Fungal Genus Venturia; Genes, Mating Type, Fungal / genetics; Genetic Variation; Genetics, Population; Plant Diseases / microbiology
TL;DR:
Characterizing the populations genetics and reproductive systems of V. effusa are important to establish the evolutionary potential of the pathogen, and thus its adaptability - and can provide a basis for informed approaches to utilizing available host resistance and determining phytosanitary needs.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2022 journal article
Telomere-to-Telomere Genome Sequences across a Single Genus Reveal Highly Variable Chromosome Rearrangement Rates but Absolute Stasis of Chromosome Number
Journal of Fungi, 8(7), 670.
author keywords: Epichloe; genome structure; chromosome evolution; structural variation
TL;DR:
It is found that the striking distinction between gene-rich and repeat-rich regions previously reported for isolated species is ubiquitous across the Epichloë genus, suggesting that different modes of evolution are acting to create nucleotide and chromosome-scale changes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2021 journal article
Mating Type Idiomorphs, Heterothallism, and High Genetic Diversity in Venturia carpophila, Cause of Peach Scab
Phytopathology®, 111(2), 408–424.
author keywords: alpha-box; ascomycete; asexual reproduction; HMG-domain; mating-type gene; MAT equilibrium; MAT locus; mycology; population biology; sexual reproduction
MeSH headings : Fungal Genus Venturia; Genes, Mating Type, Fungal / genetics; Genetic Variation; Plant Diseases; Prunus persica; Sequence Analysis, DNA
TL;DR:
Mating type identification in V. carpophila provides a basis for understanding reproductive methods of the pathogen and can be a base for further studies of genetics of the peach scab pathogen.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2021 journal article
The First Genomic Resources for Phymatotrichopsis omnivora, a Soilborne Pezizomycete Pathogen with a Broad Host Range
Phytopathology®, 111(10), 1897–1900.
MeSH headings : Ascomycota / genetics; Genomics; Host Specificity; Plant Diseases
TL;DR:
Draft genome sequences of four P. omnivora isolates obtained from cotton and alfalfa, growing in Texas and Oklahoma, USA, will provide new insights into the biology of the fungus, including the factors responsible for its broad host range and pathogenicity.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2020 journal article
Chromosome-Level Reference Genome of Venturia effusa, Causative Agent of Pecan Scab
Molecular Plant-Microbe Interactions®, 33(2), 149–152.
author keywords: genomics; metabolomics; proteomics
MeSH headings : Ascomycota / genetics; Carya / microbiology; Chromosomes, Fungal / genetics; Plant Diseases / microbiology
TL;DR:
This genome represents the first full chromosome-level assembly of any Venturia species and the likely causative mutation of the albino phenotype was identified as a single base insertion and a resulting frameshift in the gene encoding the polyketide synthase ALM1.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2020 journal article
Correction: Krauss, J., et al. <i>Epichloë</i> Endophyte Infection Rates and Alkaloid Content in Commercially Available Grass Seed Mixtures in Europe. <i>Microorganisms</i> 2020, <i>8</i>, 498
Microorganisms.
TL;DR:
The authors wish to make the following correction to this paper: the number of protons in the Higgs boson particle is 2, not 3 as originally reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2020 journal article
Epichloë Endophyte Infection Rates and Alkaloid Content in Commercially Available Grass Seed Mixtures in Europe
Microorganisms, 8(4), 498.
author keywords: Epichloe spp; grass endophytes; cool-season grass species; infection rates; alkaloids; toxicity; livestock; horses; Lolium perenne; perennial ryegrass
TL;DR:
As Epichloë infected seed mixtures can harm livestock, when infected grasses become dominant in the seeded grasslands, it is recommended seed producers to test and communicate Epicloë infection status or avoiding Epich Loë infected Seed Mixtures.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2020 journal article
First description of the sexual stage of Venturia effusa, causal agent of pecan scab
Mycologia, 112(4), 711–721.
author keywords: Epidemiology; genetic recombination; heterothallism; meiosis
MeSH headings : Carya / microbiology; Fungal Genus Venturia / genetics; Fungal Genus Venturia / growth & development; Fungal Genus Venturia / physiology; Genes, Mating Type, Fungal / genetics; Genotype; Hyphae / genetics; Hyphae / growth & development; Hyphae / physiology; Melanins / biosynthesis; Melanins / genetics; Microsatellite Repeats / genetics; Mutation; Plant Diseases / microbiology; Recombination, Genetic; Spores, Fungal / genetics; Spores, Fungal / growth & development; Spores, Fungal / physiology; Time Factors
Source: ORCID
Added: January 31, 2023
2019 article
Chromosome-level genome reference of Venturia effusa, causative agent of pecan scab
Winter, D. J., Charlton, N. D., Krom, N., Shiller, J., Bock, C. H., Cox, M. P., & Young, C. A. (2019, August 24). (Vol. 8). Vol. 8.
TL;DR:
This genome represents the first full chromosome level assembly of any Venturia species and the likely causative mutation of the albino phenotype was identified as a single base insertion and a resulting frameshift in the gene encoding the polyketide synthase ALM1.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2019 journal article
Digital Imaging to Evaluate Root System Architectural Changes Associated with Soil Biotic Factors
Phytobiomes Journal, 3(2), 102–111.
author keywords: agriculture; cotton root rot; Lucerne; Medicago sativa; microorganism; mycology; phenotyping; plant pathology
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2019 journal article
Epichloe novae-zelandiae, a new endophyte from the endemic New Zealand grass Poa matthewsii
New Zealand Journal of Botany, 8, 1–18.
TL;DR:
Endophytes of native grasses of New Zealand may provide a genetic resource that could be exploited for developing pasture grass cultivars with improved performance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2019 article
First description of the sexual stage of Venturia effusa, causal agent of pecan scab
Charlton, N. D., Yi, M., Bock, C. H., Zhang, M., & Young, C. A. (2019, September 30). (Vol. 9). Vol. 9.
TL;DR:
The results of this study demonstrate the heterothallic nature of V. effusa and determine the impact of determining the source of the overwintering ascostroma will aid in management decisions to reduce the primary inoculum in the disease cycle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2019 journal article
Infection Rates and Alkaloid Patterns of Different Grass Species with Systemic Epichloë Endophytes
Applied and Environmental Microbiology, 85(17).
Ed(s): E. Master
author keywords: Epichloe spp.; alkaloid pathway genes; chemical diversity; cool-season grass species; grass endophytes; infection rates
MeSH headings : Alkaloids / analysis; Animals; Chromatography, High Pressure Liquid; Dactylis / chemistry; Dactylis / microbiology; Endophytes / chemistry; Endophytes / physiology; Epichloe / chemistry; Epichloe / physiology; Festuca / chemistry; Festuca / microbiology; Gas Chromatography-Mass Spectrometry; Germany; Livestock; Lolium / chemistry; Lolium / microbiology; Poaceae / chemistry; Poaceae / microbiology; Species Specificity; Symbiosis; Tandem Mass Spectrometry
TL;DR:
Symbiotic Epichloë species are fungal endophytes of cool-season grasses that can produce alkaloids with toxicity to vertebrates and/or invertebrates and that in Germany, infection rates and alkAloids differ between grass species and that some of the alkaloid can be toxic to livestock.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2019 journal article
Orthologous peramine and pyrrolopyrazine‐producing biosynthetic gene clusters in Metarhizium rileyi, Metarhizium majus and Cladonia grayi
Environmental Microbiology.
MeSH headings : Ascomycota / genetics; Genes, Fungal; Heterocyclic Compounds, 2-Ring / metabolism; Metarhizium / genetics; Multigene Family; Peptide Synthases; Poaceae / microbiology; Polyamines / metabolism
TL;DR:
It is confirmed that PerA is the only pathway-specific protein required for peramine biosynthesis, and the perA homologue from M. rileyi is shown to encode a functional peramine synthetase, establishing a precedent for distribution of perA orthologs beyond genus Epichloë.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2019 journal article
Variation Among Orchardgrass (Dactylis glomerata) Germplasm for Choke Prevalence Caused by Epichloë typhina
Plant Disease, 103(2), 324–330.
TL;DR:
Evaluated the variation in orchardgrass cultivars and accessions for choke prevalence and characterized infected plants for endophyte secondary metabolite and mating type gene presence and found multiple infection events rather than a single infection event that spread to multiple tillers.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2018 journal article
A Year of Phytobiomes
Phytobiomes Journal, 2(2), 53–54.
Source: ORCID
Added: January 31, 2023
2018 article
Digital imaging to evaluate root system architectural changes associated with soil biotic factors
Mattupalli, C., Seethepalli, A., York, L. M., & Young, C. A. (2018, December 23).
TL;DR:
Data indicated that the survivor plants compensated for damage or loss to the taproot through the development of more lateral and crown roots, and that a suite of multivariate features could be used to automatically classify roots as from survivor or asymptomatic zones.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2018 journal article
Evidence for Sexual Reproduction: Identification, Frequency, and Spatial Distribution of Venturia effusa (Pecan Scab) Mating Type Idiomorphs
Phytopathology®, 108(7), 837–846.
MeSH headings : Ascomycota / genetics; Ascomycota / physiology; Carya; Genes, Mating Type, Fungal / genetics; Genetic Variation; Genome, Fungal; Genotype; Plant Diseases / microbiology
TL;DR:
The apparent equilibrium of the MAT idiomorphs provides impetus for a renewed effort to search for the sexual stage of V. effusa, which is typical of a sexually reproducing fungal pathogen.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2018 journal article
Fine-Scale Population Genetic Structure and Within-Tree Distribution of Mating Types of Venturia effusa, Cause of Pecan Scab in the United States
Phytopathology®, 108(11), 1326–1336.
MeSH headings : Ascomycota / genetics; Carya / microbiology; Genes, Mating Type, Fungal / genetics; Genetic Structures; Genetic Variation; Genetics, Population; Genotype; Linkage Disequilibrium; Microsatellite Repeats / genetics; Plant Diseases / microbiology; Plant Leaves / microbiology; Southeastern United States; Spatial Analysis
TL;DR:
The results provide novel information on the characteristics of populations of V. effusa at fine spatial scales, and provide insights into the dispersal of the organism within and between trees.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2018 journal article
Molecular identification and characterization of endophytes from uncultivated barley
Mycologia, 110(3), 453–472.
author keywords: Alkaloid; Epichloe; epiphyllous growth; Hordeum; hybrid
MeSH headings : Alkaloids / analysis; Alleles; Endophytes / classification; Endophytes / genetics; Epichloe / classification; Epichloe / genetics; Epichloe / isolation & purification; Genetic Variation; Hordeum / chemistry; Hordeum / genetics; Hordeum / microbiology; Phylogeny; Seed Bank; Seeds / microbiology; Symbiosis
TL;DR:
The genetic and chemotypic diversity of endophytes present in wild Hordeum species are explored and Phylogenetic analyses of housekeeping, alkaloid biosynthesis, and mating type genes suggest that theendophytes of the infected PI lines separate into five taxa: Epichloë bromicola, Epich Loë tembladerae, and three unnamed interspecific hybrid species.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2018 journal article
Repeat elements organise 3D genome structure and mediate transcription in the filamentous fungus Epichloë festucae
PLOS Genetics, 14(10), e1007467.
Ed(s): P. Richardson
MeSH headings : AT Rich Sequence / genetics; DNA, Fungal / chemistry; DNA, Fungal / genetics; Epichloe / genetics; Fungal Proteins / genetics; GC Rich Sequence / genetics; Gene Expression Profiling / methods; Gene Expression Regulation, Fungal; Genome, Fungal / genetics; Hyphae / genetics; Repetitive Sequences, Nucleic Acid / genetics; Sequence Analysis, DNA / methods; Symbiosis / genetics
TL;DR:
A genome in which very repeat-rich blocks of DNA with discrete boundaries are interspersed by gene-rich sequences that are almost repeat-free, suggesting that their three-dimensional orientation partly encodes and regulates the symbiotic relationship formed by this organism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2018 article
Repeat elements organize 3D genome structure and mediate transcription in the filamentous fungus Epichloë festucae
Winter, D. J., Ganley, A. R. D., Young, C. A., Liachko, I., Schardl, C. L., Dupont, P.-Y., … Cox, M. P. (2018, June 4). (Vol. 6). Vol. 6.
TL;DR:
This work generates a complete and gapless genome sequence for the filamentous fungus, Epichloë festucae, and reveals a unique “patchwork” genome, in which repeat-rich blocks of DNA with discrete boundaries are interspersed by gene-rich sequences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2018 journal article
Supervised Classification of RGB Aerial Imagery to Evaluate the Impact of a Root Rot Disease
Remote Sensing.
author keywords: cotton root rot; soil-borne fungus; disease monitoring; Phymatotrichopsis omnivora
TL;DR:
The utility of high-resolution RGB aerial images for monitoring PRR disease spread in alfalfa fields was showed and the extent of al falfa stand loss caused byPRR disease was indicated.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2017 journal article
Disruption of calcineurin catalytic subunit (cnaA) in Epichloë festucae induces symbiotic defects and intrahyphal hyphae formation
Molecular Plant Pathology, 10.
author keywords: calcineurin; CnaA; Epichloe; hyphal growth
MeSH headings : Calcineurin / chemistry; Calcineurin / metabolism; Epichloe / genetics; Epichloe / metabolism; Epichloe / physiology; Gene Expression Regulation, Fungal / genetics; Gene Expression Regulation, Fungal / physiology; Hyphae / genetics; Hyphae / metabolism; Hyphae / ultrastructure; Microscopy, Confocal; Microscopy, Electron, Transmission; Symbiosis / genetics; Symbiosis / physiology
TL;DR:
Results show that E. festucae CnaA is required for fungal growth, maintaining cell wall integrity and host colonization, both in culture and in planta.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2017 journal article
Interspecific and intraspecific hybrid Epichloë species symbiotic with the North American native grass Poa alsodes
Mycologia, 109(3), 459–474.
author keywords: Alkaloid genotype; Epichloe alsodes; Epichloe schardlii var. pennsylvanica; latitudinal transect; N-acetylnorloline; peramine
MeSH headings : Endophytes / classification; Endophytes / genetics; Endophytes / isolation & purification; Epichloe / classification; Epichloe / genetics; Epichloe / isolation & purification; Genes, Fungal; Genes, Mating Type, Fungal; Genetic Variation; Genotype; Genotyping Techniques; Mycological Typing Techniques; Phylogeny; Poaceae / microbiology; Polymerase Chain Reaction; Recombination, Genetic; United States
TL;DR:
The endophyte presence and diversity in natural populations of Poa alsodes were evaluated along a latitudinal transect from the southern distribution range in North Carolina to New York, identifying two distinct Epichloë hybrid taxa that could easily be distinguished by polymerase chain reaction genotyping.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2017 journal article
Metabolism or behavior: explaining the performance of aphids on alkaloid-producing fungal endophytes in annual ryegrass (Lolium multiflorum)
Oecologia, 185(2), 245–256.
author keywords: Endophyte; Symbiosis; Metabolic rate; Insect behavior; Fitness; EPG technique
MeSH headings : Alkaloids / metabolism; Animals; Aphids / metabolism; Aphids / physiology; Endophytes / chemistry; Epichloe / chemistry; Herbivory / physiology; Lolium / microbiology; Lolium / parasitology; Lolium / physiology; Symbiosis
TL;DR:
It is hypothesized that aphids feeding on E+ plants have higher energetic demands for detoxification of fungal alkaloids, thereby negatively impacting the individual performance, population growth, and structure, and the observed lower values of SMR in E+ feeding aphids.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2017 journal article
Population Genetic Structure of Venturia effusa, Cause of Pecan Scab, in the Southeastern United States
Phytopathology, 107(5), 607–619.
MeSH headings : Ascomycota / genetics; Carya / microbiology; Genetic Variation; Genetics, Population; Genotype; Linkage Disequilibrium; Microsatellite Repeats / genetics; Plant Diseases / microbiology; Southeastern United States
TL;DR:
Venturia effusa became an issue on cultivated pecan in the last approximately 120 years (recent population expansion), and recently reported mating type genes and the sexual stage of this fungus may help explain the observed population characteristics, which bear a strong resemblance to those of other well-characterized sexually reproducing ascomycete pathogens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2017 journal article
Toxin-producing Epichloë bromicola strains symbiotic with the forage grass Elymus dahuricus in China
Mycologia, 1, 1–13.
author keywords: Endophyte; ergot alkaloids; ergovaline; indole-diterpenes; mycotoxins; terpendoles; translation elongation factor 1-alpha gene; beta-tubulin gene
MeSH headings : Alkaloids / analysis; Biosynthetic Pathways / genetics; China; Elymus / microbiology; Endophytes / genetics; Endophytes / isolation & purification; Endophytes / physiology; Epichloe / classification; Epichloe / genetics; Epichloe / isolation & purification; Epichloe / physiology; Genome, Fungal; Genotype; Multiplex Polymerase Chain Reaction; Mycotoxins / analysis; Sequence Analysis, DNA; Symbiosis
TL;DR:
The authors characterized genotypes and alkaloid profiles of Epichloë bromicola isolates symbiotic with Elymus dahuricus, an important forage grass in rangelands of China, and found the presence of ergot alkaloids and indole-diterpenes in this grass is a potential concern for managers of grazing livestock.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2017 journal article
Variation in the Prevalence and Transmission of Heritable Symbionts Across Host Populations in Heterogeneous Environments
Microbial Ecology, 74(3), 640–653.
author keywords: Vertical transmission; Epichloe spp.; Endophytic fungi-grass symbiosis; Plant-microbe; Symbiont prevalence; Hybridization
MeSH headings : Arkansas; Elymus / microbiology; Elymus / physiology; Endophytes / physiology; Environment; Midwestern United States; Southwestern United States; Symbiosis
TL;DR:
Survey of populations of two native grasses across the southern Great Plains reveals substantial variability in symbiont prevalence and transmission across host populations and identifies symbionT genotype, and to a lesser extent, the abiotic environment as sources of this variation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2017 journal article
Welcome to Phytobiomes
Phytobiomes Journal.
TL;DR:
In 2015, APS brought together a diverse community of scientists in Washington DC for a strategically timed meeting to spearhead a new paradigm for crop improvement focusing on phytobiome-based approaches.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2016 journal article
Long-term ungulate exclusion reduces fungal symbiont prevalence in native grasslands.
181(4), 1151–1161,
author keywords: Epichloe; Epidemiology; Festuca; Herbivory; Mutualism
MeSH headings : Animals; Endophytes; Epichloe; Grassland; Poaceae / microbiology; Prevalence; Symbiosis
TL;DR:
It is shown that native ungulates can be an important driver of symbiont prevalence in native plant populations, even in the absence of evidence for direct mechanisms of mammal deterrence.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2016 journal article
The Effect of Endophytic Fungi on Nematode Populations in Summer-dormant and Summer-active Tall Fescue
Journal of Nematology, 48(2), 87–94.
TL;DR:
Novel endophyte infection enhances suitability of Flecha MaxQ as a nematode host and cultivars infected with common toxic or novelendophyte strains are compared.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2015 journal article
A mutualistic endophyte alters the niche dimensions of its host plant
AoB PLANTS, 7(0), plv005–plv005.
author keywords: Epichloe; fungal endophyte; mutualism; Poa leptocoma; Poa reflexa; symbiosis
TL;DR:
A symbiotic relationship is identified as a potential mechanism facilitating the coexistence of two species, suggesting that symbiont effects on host niche may have community-level consequences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2015 journal article
De Novo Assembly and Characterization of Tall Fescue Transcriptome under Water Stress
The Plant Genome, 8(2), 0.
TL;DR:
Identification of genes or transcription factors related to water‐stress tolerance and development of a comprehensive molecular marker system to facilitate marker‐assisted breeding in tall fescue are lead to.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2015 journal article
Disparate Independent Genetic Events Disrupt the Secondary Metabolism Gene perA in Certain Symbiotic Epichloë Species
Appl. Environ. Microbiol., 81(8), 2797–2807.
Ed(s): D. Cullen
MeSH headings : Epichloe / genetics; Epichloe / physiology; Fungal Proteins / genetics; Fungal Proteins / metabolism; Heterocyclic Compounds, 2-Ring / chemistry; Molecular Sequence Data; Mutation; Peptide Synthases / genetics; Peptide Synthases / metabolism; Phylogeny; Poaceae / microbiology; Polyamines / chemistry; Polymerase Chain Reaction; Secondary Metabolism / genetics; Sequence Analysis, DNA; Symbiosis
TL;DR:
A method was developed to predict peramine chemotypes by combining PCR product size polymorphism analysis with sequencing of the perA adenylation domains and a number of novel point, deletion, and insertion mutations responsible for abolishing peramine production in full-length perA alleles were identified.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2015 journal article
Endophytic Epichloë species and their grass hosts: from evolution to applications
Plant Mol Biol, 90(6), 665–675.
author keywords: Fungal endophytes; Grass; Genetic variation; Alkaloids; Coevolution
MeSH headings : Alkaloids / genetics; Alkaloids / metabolism; Biological Evolution; Ecosystem; Endophytes / physiology; Epichloe / genetics; Epichloe / physiology; Genetic Variation; Phylogeny; Poaceae / genetics; Poaceae / microbiology; Symbiosis
TL;DR:
These findings underscore the importance of genetic interplay between the fungus and the host in shaping their coevolution and ecological role in both natural grass ecosystems, and in the agricultural arena.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2015 journal article
Genetics, Genomics and Evolution of Ergot Alkaloid Diversity
Toxins, 7(4), 1273–1302.
MeSH headings : Ergot Alkaloids / biosynthesis; Ergot Alkaloids / chemistry; Ergot Alkaloids / genetics; Genetic Loci; Genetic Variation; Genomics; Humans; Phylogeny; Synteny
TL;DR:
Results of comparative genomics and phylogenomic analyses reveal multiple examples of three evolutionary processes that have generated ergot-alkaloid diversity: gene gains, gene losses, and gene sequence changes that have led to altered substrates or product specificities of the enzymes that they encode (neofunctionalization).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2015 journal article
Two distinct Epichloe species symbiotic with Achnatherum inebrians, drunken horse grass
Mycologia, 107(4), 863–873.
author keywords: Clavicipitaceae; endophytes; Epichloe gansuensis; E. inebrians; ergot alkaloids; genome sequence; grasses; Hypocreales; phylogenetics; rangelands; symbiosis; toxicosis
MeSH headings : Alkaloids / metabolism; Biodiversity; China; Endophytes / classification; Endophytes / genetics; Endophytes / isolation & purification; Endophytes / physiology; Epichloe / classification; Epichloe / genetics; Epichloe / isolation & purification; Epichloe / physiology; Fungal Proteins / genetics; Fungal Proteins / metabolism; Molecular Sequence Data; Phylogeny; Poaceae / classification; Poaceae / microbiology; Symbiosis
TL;DR:
It is proposed that Ei should be raised to species rank as Epichloë inebrians given its chemotypic, genotypes, morphological and phylogenetic distinctiveness, its widespread occurrence in rangelands of northern China, and its importance in livestock toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2015 journal article
Vegetative Hyphal Fusion and Subsequent Nuclear Behavior in Epichloë Grass Endophytes
PLoS ONE, 10(4), e0121875.
Ed(s): E. Kothe
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Cell Nucleus / genetics; Cell Nucleus / metabolism; Cell Nucleus / ultrastructure; Endophytes; Epichloe / classification; Epichloe / genetics; Epichloe / metabolism; Epichloe / ultrastructure; Fungal Proteins / genetics; Fungal Proteins / metabolism; Gene Expression Regulation, Fungal; Genes, Reporter; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Hybridization, Genetic; Hyphae / genetics; Hyphae / metabolism; Hyphae / ultrastructure; Luminescent Proteins / genetics; Luminescent Proteins / metabolism; Nuclear Fusion; Phylogeny; Plasmids / chemistry; Plasmids / metabolism; Poaceae / microbiology; Poaceae / physiology; Protoplasts / metabolism; Protoplasts / ultrastructure; Spores, Fungal / genetics; Spores, Fungal / metabolism; Spores, Fungal / ultrastructure; Symbiosis / physiology
TL;DR:
Results are consistent with the notion that interspecific hybrids arise from vegetative hyphal fusion, and also discuss additional factors, such as post-hybridization selection, that may be important to explain the recognized prevalence of hybrids in Epichloë species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2014 journal article
Alkaloid Genotype Diversity of Tall Fescue Endophytes
Crop Science, 54(2), 667.
Source: ORCID
Added: January 31, 2023
2014 journal article
Alkaloid Variation Among Epichloid Endophytes of Sleepygrass (Achnatherum robustum) and Consequences for Resistance to Insect Herbivores
J Chem Ecol, 41(1), 93–104.
MeSH headings : Alkaloids / analysis; Animals; Aphids / drug effects; Aphids / physiology; Endophytes / chemistry; Epichloe / chemistry; Epichloe / genetics; Ergolines / analysis; Ergonovine / analysis; Ergonovine / pharmacology; Ergot Alkaloids / analysis; Genetic Variation; Herbivory; Indoles / analysis; Insecticides / pharmacology; Lysergic Acid Diethylamide / analogs & derivatives; Lysergic Acid Diethylamide / analysis; New Mexico; Poaceae / chemistry; Poaceae / microbiology; Poaceae / physiology
TL;DR:
The results of this study suggest that alkaloids produced by the Cloudcroft endophyte, specifically ergonovine, have insecticidal properties.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2014 journal article
Characterization of Epichloë coenophiala within the US: are all tall fescue endophytes created equal?
Front. Chem., 2.
author keywords: Neotyphodium coenophialum; fescue toxicosis; ergot alkaloids; Kentucky-31 (KY31); endophyte diversity
TL;DR:
This study revealed two prominent E. coenophiala genotypes based on presence of alkaloid biosynthesis genes and SSR markers and provides insight into endophyte variation within continental US across historical and current tall fescue samples.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2014 journal article
Ether bridge formation in loline alkaloid biosynthesis
Phytochemistry, 98, 60–68.
author keywords: Epichloe spp.; Clavicipitaceae; Grass symbionts; Genome sequencing; Pyrrolizidines; Loline alkaloids; exo-1-Acetamidopyrrolizidine; Oxoglutarate/iron-dependent dioxygenase lolO
MeSH headings : Alkaloids / biosynthesis; Alkaloids / chemistry; Ethers / chemistry; Ethers / metabolism; Molecular Structure; Oxygenases / chemistry; Oxygenases / metabolism
TL;DR:
It is indicated that the non-heme iron oxygenase, LolO, is required for ether bridge formation, probably through oxidation of exo-1-acetamidopyrrolizidine.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2014 article
Fungal Endophytes of Grasses and Morning Glories, and Their Bioprotective Alkaloids
Schardl, C. L., Chen, L., & Young, C. A. (2014, March). Natural Products, pp. 125–145.
Source: ORCID
Added: January 31, 2023
2014 journal article
Highly Sensitive End-Point PCR and SYBR Green qPCR Detection of Phymatotrichopsis omnivora , Causal Fungus of Cotton Root Rot
Plant Disease, 98(9), 1205–1212.
TL;DR:
PCR-based detection methods for accurate and sensitive detection directly from symptomatic and asymptomatic plant samples are needed for disease diagnostics and pathogen identification in diagnostic laboratories, plant health inspections, and plant breeding programs.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2014 journal article
Interspecific hybridization and bioactive alkaloid variation increases diversity in endophytic Epichloë species of Bromus laevipes
FEMS Microbiol Ecol, 90(1), 276–289.
author keywords: alkaloid diversity; ergot alkaloids; lolines; indole-diterpenes; peramine; interspecific hybrid
MeSH headings : Alkaloids / analysis; Bromus / microbiology; Diterpenes / analysis; Endophytes / chemistry; Endophytes / classification; Endophytes / genetics; Endophytes / isolation & purification; Epichloe / chemistry; Epichloe / classification; Epichloe / genetics; Epichloe / isolation & purification; Ergot Alkaloids / analysis; Genetic Variation; Heterocyclic Compounds, 2-Ring / analysis; Hybridization, Genetic; Indoles / analysis; Phylogeny; Polyamines / analysis; Symbiosis
TL;DR:
A multifaceted approach combining phylogenetic, genotypic, and chemotypic analyses allowed us to reconstruct the diverse evolutionary histories of Epichloë species present within B. laevipes and highlight the complex and dynamic processes underlying these grass-endophyte symbioses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2014 journal article
Stockpiled Forage Yield and Nutritive Value of Summer-Dormant and Summer-Active Tall Fescue in a Marginal Environment
Forage and Grazinglands, 12(1), 0.
TL;DR:
The yield and nutritive value of stockpiled summerdormant tall fescue were similar to that of summer-active tall feshue, and at the end of the study, severe drought occurred in the area, resulting in summer- Active failure but summer-Dormant persistence.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2013 journal article
Currencies of mutualisms: sources of alkaloid genes in vertically transmitted epichloae
Toxins, 6;5(6):1064-88.
Source: ORCID
Added: January 31, 2023
2013 journal article
Deletion and Gene Expression Analyses Define the Paxilline Biosynthetic Gene Cluster in Penicillium paxilli
Toxins, 5(8), 1422–1446.
author keywords: indole-diterpene; paxilline; prenylation
MeSH headings : Amino Acid Sequence; Cloning, Molecular; Computational Biology; Diterpenes / metabolism; Escherichia coli; Gene Deletion; Gene Expression; Genes, Fungal; Genetic Loci; Indole Alkaloids / metabolism; Indoles / metabolism; Molecular Sequence Data; Multigene Family; Mycotoxins / metabolism; Penicillium / genetics; Penicillium / metabolism; Sequence Analysis, DNA; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
Insight is provided into the P. paxilli indole-diterpene locus and reviews the recent advances identified in paxilline biosynthesis, which can be found as two disparate clades, not supported by prenylation type.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2013 journal article
FORAGES AND PASTURES SYMPOSIUM: Fungal endophytes of tall fescue and perennial ryegrass: Pasture friend or foe?
Journal of Animal Science, 91(5), 2379–2394.
author keywords: alkaloids; animal production; endophyte; perennial ryegrass; tall fescue; toxicosis
MeSH headings : Animal Feed / analysis; Animal Husbandry; Animals; Australia; Climate Change; Conservation of Natural Resources; Ecosystem; Endophytes / physiology; Epichloe / physiology; Livestock; Lolium / microbiology; Neotyphodium / physiology; New Zealand; United States
TL;DR:
The biology of tall fescue and perennial ryegrass and the impact of grass-endophyte associations on the sustainability of pasture ecosystems and their likely response to future changes in climate are described and management strategies focused predominantly on the success of endophyte-infected perennial rrass in New Zealand and Australia are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2013 journal article
Plant-Symbiotic Fungi as Chemical Engineers: Multi-Genome Analysis of the Clavicipitaceae Reveals Dynamics of Alkaloid Loci
PLoS Genet, 9(2), e1003323.
Ed(s): J. Heitman
MeSH headings : Alkaloids / chemistry; Alkaloids / classification; Alkaloids / genetics; Alkaloids / metabolism; Claviceps / genetics; Claviceps / metabolism; Claviceps / pathogenicity; Epichloe / genetics; Epichloe / metabolism; Epichloe / pathogenicity; Ergot Alkaloids / genetics; Ergot Alkaloids / metabolism; Gene Expression Regulation, Fungal; Hypocreales / genetics; Hypocreales / metabolism; Neotyphodium; Poaceae / genetics; Poaceae / metabolism; Poaceae / parasitology; Selection, Genetic; Symbiosis / genetics
TL;DR:
The organization and dynamics of alkaloid loci and abundant repeat blocks in the epichloae suggested that these fungi are under selection for alkaloids diversification, and it is suggested that such selection is related to the variable life histories of the epICHloae, their protective roles as symbionts, and their associations with the highly speciose and ecologically diverse cool-season grasses.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2012 journal article
Characterization and Effectiveness of Co-inoculation of Strains on Annual Medics
Crop Science, 0(0), 1.
TL;DR:
An inoculum blend suitable for annual medic species adapted to the southern Great Plains and suitable and more economic for use with a mixture of medic species that may provide expansion of the grazing season is generated.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2012 journal article
Chemotypic diversity of epichloae, fungal symbionts of grasses
Fungal Ecology, 5(3), 331–344.
author keywords: Alkaloids; Biosynthesis genes; Clavicipitaceae; Epichloe; Fungus species; Neotyphodium; Poaceae; Pooideae; Symbiosis; Vertical transmission
TL;DR:
Compared to sexual epichloae, many asexual epicloae produce high levels of alkaloids – particularly lolines – suggesting that strict vertical transmission selects for enhanced capability of host protection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2012 journal article
Chemotypic diversity of epichloae, fungal symbionts of grasses
Fungal Ecology, 30;5(3):331-44.
Source: ORCID
Added: January 31, 2023
2012 journal article
Effects of selected endophyte and tall fescue cultivar combinations on steer grazing performance, indicators of fescue toxicosis, feedlot performance, and carcass traits-
Journal of Animal Science, 91(1), 342–355.
author keywords: carcass; endophyte; fescue toxicosis; grazing; stocker calf; tall fescue
MeSH headings : Animal Feed / analysis; Animal Husbandry / economics; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Temperature; Cattle; Cattle Diseases / chemically induced; Diet / veterinary; Ergot Alkaloids / chemistry; Ergot Alkaloids / metabolism; Male; Poaceae / classification; Poaceae / toxicity; Prolactin; Weight-Bearing
TL;DR:
Five tall fescue pastures compared for steer growth performance, toxicity, feedlot performance, and carcass traits should consider retaining ownership of these cattle through feedlot finishing to avoid market discounts and capture value from compensatory BW gains during finishing.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2012 journal article
Endophytes of native grasses from South America: Biodiversity and ecology
Fungal Ecology, 5(3), 357–363.
author keywords: Biology; Diversity; Ecology; Neotyphodium; South America
TL;DR:
Preliminary analyses indicate that some Argentinian endophytes can produce lolines but are unlikely to produce lolitrem B or ergot alkaloids, and in native forage grasses, Neotyphodium presents a mutualistic behaviour, conferring enhanced growth and promoting the symbiosis with arbuscular mycorrhizal fungi.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2012 journal article
Epichloe canadensis, a new interspecific epichloid hybrid symbiotic with Canada wildrye (Elymus canadensis)
Mycologia, 104(5), 1187–1199.
author keywords: alkaloid diversity; endophyte; Epichloe amarillans; E. elymi; lolines; Neotyphodium
MeSH headings : Alkaloids / genetics; Canada; DNA, Plant / genetics; Elymus / microbiology; Endophytes / classification; Endophytes / genetics; Endophytes / ultrastructure; Epichloe / classification; Epichloe / genetics; Epichloe / ultrastructure; Ergot Alkaloids / genetics; Peptide Elongation Factor 1 / genetics; Phylogeny; Poaceae / genetics; Poaceae / microbiology; Tubulin / genetics
TL;DR:
Morphology and phylogenetic evidence support the designation of isolates from El.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2012 journal article
Genotypic and Chemotypic Diversity of Neotyphodium Endophytes in Tall Fescue from Greece
Applied and Environmental Microbiology, 78(16), 5501–5510.
MeSH headings : Alkaloids / analysis; DNA, Fungal / chemistry; DNA, Fungal / genetics; Endophytes / chemistry; Endophytes / genetics; Festuca / microbiology; Fungal Proteins / genetics; Genetic Variation; Genotype; Greece; Molecular Sequence Data; Neotyphodium / chemistry; Neotyphodium / cytology; Neotyphodium / genetics; Neotyphodium / growth & development; Phenotype; Sequence Analysis, DNA; Spores, Fungal / cytology
TL;DR:
Variation in alkaloid gene content, specifically the presence and absence of genes, and copy number of gene clusters explained the alkaloids observed in the endophyte-infected tall fescue, with one exception.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2012 journal article
Mediterranean and Continental Tall Fescue: I. Effects of Endophyte Status on Leaf Extension, Proline, Mono- and Disaccharides, Fructan, and Freezing Survivability
Crop Science, 52(1), 451.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2011 journal article
Abundant Degenerate Miniature Inverted-Repeat Transposable Elements in Genomes of Epichloid Fungal Endophytes of Grasses
Genome Biology and Evolution, 3(0), 1253–1264.
author keywords: Epichloe; transposable element; endophyte; genome evolution; fungi
MeSH headings : DNA Transposable Elements; Endophytes / genetics; Endophytes / isolation & purification; Evolution, Molecular; Genome, Fungal; Hypocreales / genetics; Hypocreales / isolation & purification; Inverted Repeat Sequences; Molecular Sequence Data; Poaceae / microbiology
TL;DR:
Analysis of the draft genome sequence of the fungal endophyte Epichloë festucae revealed 13 MITE families that make up almost 1% of the E. Festucae genome, and relics of putative autonomous parent elements were identified for three families.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2011 journal article
Effectiveness of Inoculants on Annual Medics
Crop Science, 51(5), 2249.
TL;DR:
Data indicate that there are differences in rhi- zobia specifi city of annual medic species, and further research is warranted to improve nodu- lation of these legumes in the fi eld.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2011 journal article
Registration of ‘Texoma’ MaxQ II Tall Fescue
Journal of Plant Registrations, 5(1), 14.
Source: ORCID
Added: January 31, 2023
2010 journal article
Agronomic Performance and Lamb Health among Several Tall Fescue Novel Endophyte Combinations in the South-Central USA
Crop Science, 50(4), 1552.
TL;DR:
Several tall fescue-novel endophyte combinations, and in particular PDF AR584, appear to be suited for the south-central United States, based on competitive agronomic performance and health of grazing lambs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2010 journal article
Phymatotrichum (cotton) root rot caused by Phymatotrichopsis omnivora : retrospects and prospects
Molecular Plant Pathology, 11(3), 325–334.
MeSH headings : Ascomycota / classification; Ascomycota / physiology; Genomics; Gossypium / microbiology; Host-Pathogen Interactions; Plant Diseases / microbiology; Plant Diseases / prevention & control; Plant Diseases / statistics & numerical data; Plant Roots / microbiology
TL;DR:
This review is aimed at discussing the recent molecular and genomic approaches that have been undertaken to better understand the disease development at the molecular level with the ultimate goal of developing resistant germplasm.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2010 journal article
Prevalence of an intraspecific Neotyphodium hybrid in natural populations of stout wood reed (Cinna arundinacea L.) from eastern North America
Mycologia, 103(1), 75–84.
author keywords: endophyte; ergot alkaloids; indole-diterpenes; lolines; Neotyphodium schardlii; peramine
MeSH headings : Base Sequence; DNA, Fungal / chemistry; DNA, Fungal / genetics; Hybridization, Genetic; Indiana; Molecular Sequence Data; Neotyphodium / genetics; Neotyphodium / isolation & purification; Neotyphodium / ultrastructure; Peptide Elongation Factor 1 / chemistry; Peptide Elongation Factor 1 / genetics; Phylogeny; Poaceae / microbiology; Polymerase Chain Reaction; Sequence Alignment; Symbiosis; Tubulin / chemistry; Tubulin / genetics
TL;DR:
P phylogenetic analysis of mainly non-coding sequence from these genes revealed that both copies in each isolate were inherited from Epichloë typhina ancestors, indicating that the C. arundinacea endophytes arose through intraspecific hybridization between two E. typhina progenitors with extant relatives infecting hosts Poa nemoralis and Poa pratensis.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2009 journal article
Genetic Variation within and among Wildrye ( and ) Populations from the Southern Great Plains
Crop Science, 49(3), 913.
TL;DR:
Genetic variation within populations was minimal and comparable to that of the barley cultivars, unlike many ancestral cultivars and landraces of self-pollinated crops, CWR and VWR populations consisted of essentially pure lines and can be handled as such in a breeding program.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2009 journal article
Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans
NATURE, 461(7262), 393–398.
Contributors: B. Haas *, S. Kamoun *, M. Zody *, R. Jiang *, R. Handsaker *, L. Cano *, M. Grabherr *, C. Kodira*
MeSH headings : Algal Proteins / genetics; DNA Transposable Elements / genetics; DNA, Intergenic / genetics; Evolution, Molecular; Genome / genetics; Host-Pathogen Interactions / genetics; Humans; Ireland; Molecular Sequence Data; Necrosis; Phenotype; Phytophthora infestans / genetics; Phytophthora infestans / pathogenicity; Plant Diseases / immunology; Plant Diseases / microbiology; Solanum tuberosum / immunology; Solanum tuberosum / microbiology; Starvation
TL;DR:
The sequence of the P. infestans genome is reported, which at ∼240 megabases (Mb) is by far the largest and most complex genome sequenced so far in the chromalveolates and probably plays a crucial part in the rapid adaptability of the pathogen to host plants and underpins its evolutionary potential.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
13. Climate Action
(Web of Science)
Sources: ORCID, Web Of Science
Added: August 6, 2018
2009 journal article
In Planta Expression Screens of Phytophthora infestans RXLR Effectors Reveal Diverse Phenotypes, Including Activation of the Solanum bulbocastanum Disease Resistance Protein Rpi-blb2
THE PLANT CELL ONLINE, 21(9), 2928–2947.
MeSH headings : Algal Proteins / metabolism; Alleles; Amino Acid Sequence; Cell Death; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Immunity, Innate; Molecular Sequence Data; Phytophthora infestans / metabolism; Phytophthora infestans / pathogenicity; Plant Proteins / genetics; Plant Proteins / metabolism; Polymorphism, Genetic; RNA, Plant / metabolism; Sequence Alignment; Sequence Analysis, DNA; Solanum / genetics; Solanum / immunology; Solanum / metabolism; Tobacco / genetics; Tobacco / immunology; Tobacco / metabolism
TL;DR:
The Irish potato famine pathogen Phytophthora infestans is predicted to secrete hundreds of effector proteins and it is revealed that 16 of the 62 examined effectors cause phenotypes when expressed inside plant cells, and structure-function experiments indicated that a 34–amino acid region in the C-terminal half of AVRblb2 is sufficient for triggering Rpi-blb 2 hypersensitivity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2009 journal article
Indole-Diterpene Biosynthetic Capability of Epichloe Endophytes as Predicted by ltm Gene Analysis
Applied and Environmental Microbiology, 75(7), 2200–2211.
MeSH headings : Blotting, Southern; Chromatography, Liquid; DNA, Fungal / genetics; Diterpenes / metabolism; Diterpenes / pharmacology; Epichloe / genetics; Epichloe / metabolism; Fungal Proteins / genetics; Indoles / metabolism; Indoles / pharmacology; Lolium / chemistry; Mass Spectrometry; Multigene Family; Mycotoxins / metabolism; Mycotoxins / pharmacology; Neotyphodium / genetics; Neotyphodium / metabolism; Neurotoxins / metabolism; Neurotoxins / pharmacology; Polymerase Chain Reaction / methods
TL;DR:
Analysis of toxin biosynthesis genes by PCR now enables a diagnostic method to screen endophytes for both beneficial and detrimental alkaloids and can be used as a resource for screening isolates required for forage improvement.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2009 article
Regulation and Functional Analysis of Bioprotective Metabolite Genes from the Grass Symbiont Epichloe festucae
Scott, B., Wrenn, R. E., May, K. J., Takemoto, D., Young, C. A., Tanaka, A., … Johnson, R. D. (2009, August). Recent Developments in Management of Plant Diseases, pp. 199–213.
author keywords: Lolitrem B; Ergovaline; Peramine; Neotyphodium lolii; Epichloe festucae
TL;DR:
This work has cloned and functionally analysed genes for the synthesis of three classes of the bioprotective molecules, peramine, lolitrem B and ergovaline, and proposed biosynthetic schemes forThe synthesis of the metabolites.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2008 journal article
Effector Genomics Accelerates Discovery and Functional Profiling of Potato Disease Resistance and Phytophthora Infestans Avirulence Genes
PLoS ONE, 3(8), e2875.
Ed(s): H. El-Shemy
MeSH headings : Cloning, Molecular; Fungal Proteins / genetics; Gene Expression Profiling; Genomics; Immunity, Innate; Phytophthora / genetics; Phytophthora / pathogenicity; Plant Diseases / genetics; Solanum tuberosum / genetics; Virulence / genetics
TL;DR:
The findings indicate that effector genomics enables discovery and functional profiling of late blight R genes and Avr genes at an unprecedented rate and promises to accelerate the engineering ofLate blight resistant potato varieties.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2008 journal article
Neotyphodium fungal endophytes confer physiological protection to perennial ryegrass (Lolium perenne L.) subjected to a water deficit
Environmental and Experimental Botany, 63(1-3), 183–199.
author keywords: Neotyphodium lolii; water stress; perennial ryegrass; endophyte; lolitrems; ergovatine; proline
TL;DR:
It is demonstrated that N. lolii can confer protection to perennial ryegrass from water stress and that levels of the bioprotective metabolites, lolitrem B and ergovaline were altered in response to this abiotic stress in a manner that was specific for each symbiotic association.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2008 journal article
The genetic basis for indole-diterpene chemical diversity in filamentous fungi
Mycological Research, 112(2), 184–199.
author keywords: Ascomycota; endophytes; gene cloning; gene expression; gene regulation; metabolites
MeSH headings : Amino Acid Sequence; Animals; Dimethylallyltranstransferase / chemistry; Dimethylallyltranstransferase / genetics; Dimethylallyltranstransferase / metabolism; Diterpenes / chemistry; Diterpenes / metabolism; Fungal Proteins / chemistry; Fungal Proteins / genetics; Fungal Proteins / metabolism; Fungi / chemistry; Fungi / genetics; Fungi / metabolism; Humans; Indoles / chemistry; Indoles / metabolism; Mice; Molecular Sequence Data; Multigene Family; Sequence Alignment
TL;DR:
Important insights into how the indole-diterpene backbone is synthesised and decorated have been obtained using P. paxilli mutants in this pathway, and a review provides an overview of these recent developments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2006 journal article
A Polyketide Synthase Gene Required for Biosynthesis of the Aflatoxin-like Toxin, Dothistromin
Mycopathologia, 161(5), 283–294.
author keywords: aflatoxin biosynthesis; Dothistroma septosporum; dothistromin biosynthesis; epoxide hydrolase; red-band needle blight; sporulation
MeSH headings : Amino Acid Sequence; Anthraquinones / metabolism; Ascomycota / enzymology; Ascomycota / genetics; Ascomycota / growth & development; Ascomycota / metabolism; Base Sequence; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Molecular Sequence Data; Polyketide Synthases / genetics; Polyketide Synthases / metabolism; RNA, Fungal / chemistry; RNA, Fungal / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Transformation, Genetic
TL;DR:
Biochemical and genetic studies suggested that there are common steps in the biosynthetic pathways for these metabolites and showed similarities between some of the genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2006 journal article
A complex gene cluster for indole-diterpene biosynthesis in the grass endophyte Neotyphodium lolii
Fungal Genetics and Biology, 43(10), 679–693.
author keywords: Neotyphodium lolii; indole diterpenes; lolitrem B; ltm gene clusters; retrotransposons; Penicillium paxilli; LTM locus
MeSH headings : Chromatography, High Pressure Liquid / methods; Chromosome Mapping / methods; Computational Biology; Diterpenes / chemistry; Diterpenes / metabolism; Expressed Sequence Tags; Gene Expression Regulation, Fungal / genetics; Genes, Fungal / genetics; Hypocreales / genetics; Hypocreales / metabolism; Indoles / chemistry; Indoles / metabolism; Lolium / chemistry; Lolium / microbiology; Molecular Sequence Data; Molecular Structure; Multigene Family / genetics; Mycotoxins / chemistry; Mycotoxins / metabolism; Promoter Regions, Genetic / genetics; RNA, Messenger / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Symbiosis / genetics
TL;DR:
This work provides a genetic foundation for elucidating the metabolic grid responsible for the diversity of indole-diterpenes synthesized by N. lolii, a mutualistic endophyte of perennial ryegrass.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2006 journal article
The C-terminal half of Phytophthora infestans RXLR effector AVR3a is sufficient to trigger R3a-mediated hypersensitivity and suppress INF1-induced cell death in Nicotiana benthamiana
The Plant Journal, 48(2), 165–176.
author keywords: oomycetes; pathogen; effector; hypersensitive response; virulence
MeSH headings : Algal Proteins / antagonists & inhibitors; Algal Proteins / chemistry; Algal Proteins / genetics; Algal Proteins / physiology; Alleles; Amino Acid Motifs; Apoptosis; Gene Silencing; HSP90 Heat-Shock Proteins / genetics; HSP90 Heat-Shock Proteins / metabolism; Phytophthora / genetics; Phytophthora / metabolism; Phytophthora / pathogenicity; Plant Leaves / anatomy & histology; Plant Leaves / metabolism; Plant Leaves / physiology; Plant Proteins / genetics; Plant Proteins / metabolism; Polymorphism, Genetic; Protein Structure, Tertiary; Proteins; Signal Transduction; Structure-Activity Relationship; Tobacco / anatomy & histology; Tobacco / metabolism; Tobacco / physiology; Virulence Factors / genetics; Virulence Factors / metabolism; Virulence Factors / physiology
TL;DR:
Structural-function experiments indicated that the 75-amino acid C-terminal half of AVR3aKI, which excludes the RXLR region, is sufficient for avirulence and suppression functions, consistent with the view that the N- terminal region of A VR3AKI and other RXLR effectors is involved in secretion and targeting but is not required for effector activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2006 journal article
The Malarial Host-Targeting Signal Is Conserved in the Irish Potato Famine Pathogen
PLoS Pathog, 2(5), e50.
MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Animals; Conserved Sequence; Genes, Dominant; Host-Parasite Interactions / genetics; Ireland; Molecular Sequence Data; Phytophthora / genetics; Phytophthora / physiology; Plasmodium falciparum / genetics; Plasmodium falciparum / physiology; Protein Sorting Signals / genetics; Signal Transduction / genetics; Solanum tuberosum; Starvation
TL;DR:
These studies provide the first evidence to the authors' knowledge that eukaryotic microbes share equivalent pathogenic HT signals and thus conserved mechanisms to access host cells across plant and animal kingdoms that may present unique targets for prophylaxis across divergent pathogens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2005 journal article
Molecular cloning and genetic analysis of a symbiosis-expressed gene cluster for lolitrem biosynthesis from a mutualistic endophyte of perennial ryegrass
Mol Genet Genomics, 274(1), 13–29.
author keywords: Neotyphodium lolii; Epichloe festucae; lolitrem B; endophyte; retrotransposons
MeSH headings : Actins / genetics; Actins / metabolism; Alkyl and Aryl Transferases / genetics; Alkyl and Aryl Transferases / metabolism; Chromosome Walking; Cloning, Molecular; Diterpenes / metabolism; Farnesyltranstransferase; Fungal Proteins / genetics; Fungal Proteins / metabolism; Gene Deletion; Indoles / metabolism; Lolium / microbiology; Lolium / physiology; Mixed Function Oxygenases / genetics; Mixed Function Oxygenases / metabolism; Molecular Sequence Data; Multigene Family; Penicillium / enzymology; Penicillium / genetics; Polymerase Chain Reaction; RNA, Plant / genetics; RNA, Plant / metabolism; Retroelements / genetics; Symbiosis; Tubulin / genetics; Tubulin / metabolism
TL;DR:
Lolitrems are potent tremorgenic mycotoxins that are synthesised by clavicipitaceous fungal endophytes of the Epichloë/Neotyphodium group in association with grasses that confer major ecological benefits on the grass–endophyte symbiotum.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2005 journal article
Structural analysis of a peptide synthetase gene required for ergopeptine production in the endophytic fungus Neotyphodium lolii
DNA Sequence, 16(5), 379–385.
author keywords: peptide synthetase; ergopeptine; adenylation domain; intron position; endophyte; ergovaline
MeSH headings : Amino Acid Sequence; Claviceps / genetics; Cloning, Molecular; Ergot Alkaloids / biosynthesis; Genes, Fungal; Hypocreales / genetics; Molecular Sequence Data; Peptide Synthases / genetics; Phylogeny; Protein Structure, Tertiary; Sequence Homology, Amino Acid
TL;DR:
The gene encoding this enzyme in the endophytic fungus Neotyphodium lolii was analyzed and compared to a homologous gene from the ergot fungus Claviceps purpurea, which provided new information on the structure and distribution of this important peptide synthetase involved in ergot alkaloid biosynthesis.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2003 article
Genetic Manipulation of Clavicipitalean Endophytes
Scott, B., & Young, C. (2003, July). Clavicipitalean Fungi.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2003 journal article
Molecular analysis of two cytochrome P450 monooxygenase genes required for paxilline biosynthesis in Penicillium paxilli , and effects of paxilline intermediates on mammalian maxi-K ion channels
Molecular Genetics and Genomics, 270(1), 9–23.
author keywords: Penicillium paxilli; indole-diterpenes; paxilline; cytochrome P450; monooxygenases; maxi-K channels
MeSH headings : Amino Acid Sequence; Animals; Conserved Sequence; Cytochrome P-450 Enzyme System / genetics; DNA, Complementary / genetics; Gene Deletion; Genes, Bacterial; Genetic Complementation Test; Indoles / metabolism; Indoles / pharmacology; Large-Conductance Calcium-Activated Potassium Channels; Mammals; Molecular Sequence Data; Multigene Family; Mutagenesis; Penicillium / enzymology; Penicillium / genetics; Potassium Channels, Calcium-Activated / drug effects; Potassium Channels, Calcium-Activated / physiology; Recombinant Proteins / drug effects; Recombinant Proteins / metabolism; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid
TL;DR:
Chemical complementation of paxilline biosynthesis in paxG (geranygeranyl diphosphate synthase) and paxP, but not paxQ, mutants by the external addition of 13-desoxypaxillines confirms that PaxG and PaxP precede PaxQ, and are functionally part of the same biosynthetic pathway.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: January 31, 2023
2001 journal article
Elimination of ergovaline from a grass-Neotyphodium endophyte symbiosis by genetic modification of the endophyte
Proceedings of the National Academy of Sciences, 98(22), 12820–12825.
MeSH headings : Base Sequence; Ergotamines / metabolism; Fungi / genetics; Molecular Sequence Data; Poaceae / microbiology; Polymerase Chain Reaction; Symbiosis; Transformation, Genetic
TL;DR:
Disruption of this gene provides a means to manipulate the accumulation of ergovaline in endophyte-infected grasses for the purpose of determining the roles of ergopeptine inendophytes-associated traits and, potentially, for ameliorating toxicoses in livestock.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
2001 journal article
Molecular cloning and genetic analysis of an indole-diterpene gene cluster from Penicillium paxilli
Mol Microbiol, 39(3), 754–764.
MeSH headings : Alkyl and Aryl Transferases / genetics; Chromosome Walking; Cloning, Molecular / methods; Diterpenes / metabolism; Farnesyltranstransferase; Gene Deletion; Genes, Fungal; Indoles / metabolism; Molecular Sequence Data; Multigene Family; Mycotoxins / biosynthesis; Penicillium / genetics; Penicillium / growth & development; Penicillium / metabolism; Plasmids / genetics; Sequence Analysis, DNA
TL;DR:
Targeted replacement of paxG confirmed that it is essential for paxilline biosynthesis but dispensable for growth, and the first description of the molecular cloning and genetic analysis of an indole‐diterpene gene cluster is described.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
1998 journal article
Paxilline-negative mutants of Penicillium paxilli generated by heterologous and homologous plasmid integration
Current Genetics, 33(5), 368–377.
author keywords: Penicillium paxilli; paxilline mutants; plasmid tagging; homologous recombination; deletion mutations; pAN7-1
MeSH headings : Chromosome Mapping; Chromosomes, Fungal; Crossing Over, Genetic; Escherichia coli / genetics; Gene Deletion; Genomic Library; Indoles / analysis; Mycotoxins / genetics; Penicillium / genetics; Penicillium / metabolism; Plasmids; Repetitive Sequences, Nucleic Acid; Transformation, Genetic
TL;DR:
Telomeric fingerprinting of genomic digests of P. paxilli, combined with pulsed-field gel electrophoresis of chromosomal DNA, established that there are a minimum of eight chromosomes in this fungus.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
1996 journal article
Novel and Complex Chromosomal Arrangement ofRhizobium/otiNodulation Genes
MPMI, 9(3), 187.
author keywords: nodulation gene rearrangements
MeSH headings : Acyltransferases / genetics; Amidohydrolases / genetics; Amino Acid Sequence; Bacterial Proteins / genetics; Base Sequence; Chromosome Mapping; Chromosomes, Bacterial / genetics; DNA Primers / genetics; DNA, Bacterial / genetics; Fabaceae / microbiology; Gene Rearrangement; Genes, Bacterial; Genetic Complementation Test; Molecular Sequence Data; Mutagenesis, Insertional; Nitrogen Fixation / genetics; Operon; Plants, Medicinal; Rhizobium / genetics; Sequence Homology, Amino Acid; Symbiosis
TL;DR:
Mutational and structural analysis of Rhizobium loti nodulation genes in strains NZP2037 and NZP2213 showed that nodD3, nodI, nodJ, and nolL were all essential for R. loti strains to effectively nodulate the extended host Lotus pedunculatus, but were not necessary for effective nodulation of the less restrictive host, Lotus corniculatus.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
1996 journal article
PCR amplification of the fas-1 gene for the detection of virulent strains of Rhodococcus fascians
Plant Pathology, 45(3), 407–417.
TL;DR:
There is a strong relationship between the presence of the fas-1 gene and virulence of the organism.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
1991 journal article
Expression and nucleotide sequence of the Clostridium acetobutylicum beta-galactosidase gene cloned in Escherichia coli.
Journal of Bacteriology, 173(10), 3084–3095.
MeSH headings : Amino Acid Sequence; Base Sequence; Cloning, Molecular; Clostridium / enzymology; Clostridium / genetics; DNA Mutational Analysis; DNA Transposable Elements; DNA, Bacterial / genetics; Gene Expression Regulation, Bacterial; Genes, Bacterial; Molecular Sequence Data; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Restriction Mapping; beta-Galactosidase / genetics
TL;DR:
Complementation experiments indicate that the gene product of cbgR is required in cis with cbgA for expression of beta-galactosidase in E. coli, but Tn5 insertions in this gene prevent the synthesis of CbgA.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
1990 journal article
Nucleotide sequence of Rhizobium loti nod I
Nucl Acids Res, 18(22), 6691–6691.
MeSH headings : Amino Acid Sequence; Base Sequence; DNA, Fungal / chemistry; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid; Rhizobium / genetics
Source: ORCID
Added: January 31, 2023
article
Epichloë Endophytes: Models of an Ecological Strategy
Young, C., & Wilkinson, H. H. Cellular and Molecular Biology of Filamentous Fungi, pp. 660–675.
TL;DR:
The implications of this study reveal the concern that when introduced symbiota with pronounced fitness enhancements become established in nature, they run the risk of dominating communities and driving out some native plant species.
(via Semantic Scholar)
Source: ORCID
Added: January 31, 2023
article
Molecular and Genetic Analysis of Lolitrem and Peramine Biosynthetic Pathways in Epkhloë Festucae
Scott, B., Young, C., Tanaka, A., Christenseq, M., Tapper, B., & Bryan, G. Neotyphodium in Cool-Season Grasses, pp. 93–101.
Source: ORCID
Added: January 31, 2023
article
Molecular and genetic analysis of symbiosis expressed secondary metabolite genes from the mutualistic fungal endophytes Neotyphodium lolii and Epichloë festucae
Scott, B., Young, C. A., Tanaka, A., & Parker, E. J. (G. D. Robson, P. West, & G. Gadd, Eds.). Exploitation of Fungi, pp. 59–77.
Ed(s): G. Robson, P. West & G. Gadd
Source: ORCID
Added: January 31, 2023
Employment
Updated: November 10th, 2022 17:39
2022 - present
NC State University Raleigh, NC-North Carolina, US
Professor & Department Head
Entomology and Plant Pathology
Funding History
Funding history based on the linked ORCID record. Updated: October 25th, 2023 17:07
contract
January 1, 2019 - January 1, 2022
Treasure from the junk pile. Do transposable elements drive the evolution of gene expression?
Marsden Fund
contract
January 1, 2015 - January 1, 2018
When genomes collide: how allopolyploids respond to genome shock
Marsden Fund
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