Changqing Zhang

Works (3)

Updated: July 5th, 2023 15:31

2022 article

Loss of linker histone H1 in the maternal genome influences DEMETER-mediated demethylation and affects the endosperm DNA methylation landscape

Han, Q., Hung, Y.-H., Zhang, C., Bartels, A., Rea, M., Yang, H., … Hsieh, T.-F. (2022, December 22). Frontiers in Plant Science, Vol. 13.

By: Q. Han *, Y. Hung  n, C. Zhang n, A. Bartels*, M. Rea*, H. Yang*, C. Park*, X. Zhang  n ...

author keywords: epigenetics; DNA demethylation; gene imprinting; DNA glycosylase; linker histone H1
topics (OpenAlex): Plant Molecular Biology Research; Plant nutrient uptake and metabolism; Genetic Syndromes and Imprinting
TL;DR: Endosperm methylome analysis revealed that without the maternal linker histones, DME-mediated demethylation is facilitated, particularly in the heterochromatin regions, indicating that H1-containing nucleosomes are barriers for DME dem methylation. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: January 23, 2023

2019 article

Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation

Pecorelli, A., Cordone, V., Messano, N., Zhang, C., Falone, S., Amicarelli, F., … Valacchi, G. (2019, October 6). Redox Biology, Vol. 28.

By: A. Pecorelli* , V. Cordone *, N. Messano *, C. Zhang*, S. Falone *, F. Amicarelli *, J. Hayek *, G. Valacchi* 

author keywords: NLRP3; ASC; Inflammatory status; Cytokines; MeCP2
MeSH headings : Biomarkers; Cytokines / metabolism; Disease Susceptibility; Fibroblasts / metabolism; Fluorescent Antibody Technique; Humans; Inflammasomes / metabolism; Inflammation Mediators / metabolism; Interleukin-1beta / metabolism; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Protein Transport; Rett Syndrome / etiology; Rett Syndrome / metabolism
topics (OpenAlex): Genetics and Neurodevelopmental Disorders; Inflammasome and immune disorders; Adenosine and Purinergic Signaling
TL;DR: It is suggested that RTT patients exhibited a challenged inflammasome machinery at cellular and systemic level, which may contribute to the subclinical inflammatory state feedback observed in this pathology. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 30, 2019

2019 article

Maternal small RNAs mediate spatial-temporal regulation of gene expression, imprinting, and seed development in Arabidopsis

Kirkbride, R. C., Lu, J., Zhang, C., Mosher, R. A., Baulcombe, D. C., & Chen, Z. J. (2019, January 28). Proceedings of the National Academy of Sciences.

By: R. Kirkbride *, J. Lu *, C. Zhang*, R. Mosher *, D. Baulcombe * & Z. Chen *

author keywords: DNA methylation; imprinting; epigenetics; polyploidy; heterosis
MeSH headings : Arabidopsis / embryology; Arabidopsis / genetics; Arabidopsis Proteins / genetics; Gene Expression Regulation, Plant / physiology; Genomic Imprinting; Ovule; RNA, Plant / physiology; RNA, Small Interfering / genetics; Seeds / growth & development
topics (OpenAlex): Plant Molecular Biology Research; Plant nutrient uptake and metabolism; Chromosomal and Genetic Variations
TL;DR: It is demonstrated that spatial and temporal expression patterns of these genes in the endosperm are regulated by the NRPD1-mediated pathway irrespective of complete silencing (AGL91) or incomplete silencing(AGL40) of these target genes, and altered expression of these siRNA-targeted genes affects seed size. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: February 25, 2019

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