Changqing Zhang

Works (3)

Updated: July 5th, 2023 15:31

2022 journal article

Loss of linker histone H1 in the maternal genome influences DEMETER-mediated demethylation and affects the endosperm DNA methylation landscape

FRONTIERS IN PLANT SCIENCE, 13.

By: Q. Han *, Y. Hung  n, C. Zhang n, A. Bartels*, M. Rea*, H. Yang*, C. Park *, X. Zhang  n ...

author keywords: epigenetics; DNA demethylation; gene imprinting; DNA glycosylase; linker histone H1
TL;DR: Endosperm methylome analysis revealed that without the maternal linker histones, DME-mediated demethylation is facilitated, particularly in the heterochromatin regions, indicating that H1-containing nucleosomes are barriers for DME dem methylation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 23, 2023

2019 journal article

Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation

REDOX BIOLOGY, 28.

By: A. Pecorelli* , V. Cordone *, N. Messano *, C. Zhang*, S. Falone *, F. Amicarelli *, J. Hayek *, G. Valacchi* 

author keywords: NLRP3; ASC; Inflammatory status; Cytokines; MeCP2
MeSH headings : Biomarkers; Cytokines / metabolism; Disease Susceptibility; Fibroblasts / metabolism; Fluorescent Antibody Technique; Humans; Inflammasomes / metabolism; Inflammation Mediators / metabolism; Interleukin-1beta / metabolism; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Protein Transport; Rett Syndrome / etiology; Rett Syndrome / metabolism
TL;DR: It is suggested that RTT patients exhibited a challenged inflammasome machinery at cellular and systemic level, which may contribute to the subclinical inflammatory state feedback observed in this pathology. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 30, 2019

2019 journal article

Maternal small RNAs mediate spatial-temporal regulation of gene expression, imprinting, and seed development in Arabidopsis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(7), 2761–2766.

By: R. Kirkbride *, J. Lu *, C. Zhang*, R. Mosher *, D. Baulcombe * & Z. Chen *

author keywords: DNA methylation; imprinting; epigenetics; polyploidy; heterosis
MeSH headings : Arabidopsis / embryology; Arabidopsis / genetics; Arabidopsis Proteins / genetics; Gene Expression Regulation, Plant / physiology; Genomic Imprinting; Ovule; RNA, Plant / physiology; RNA, Small Interfering / genetics; Seeds / growth & development
TL;DR: It is demonstrated that spatial and temporal expression patterns of these genes in the endosperm are regulated by the NRPD1-mediated pathway irrespective of complete silencing (AGL91) or incomplete silencing(AGL40) of these target genes, and altered expression of these siRNA-targeted genes affects seed size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: February 25, 2019

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