Works (50)
Updated: August 28th, 2023 16:35
2023 journal article
Gel formulated with Bryophyllum pinnatum leaf extract promotes skin wound healing in vivo by increasing VEGF expression: A novel potential active ingredient for pharmaceuticals
FRONTIERS IN PHARMACOLOGY, 13.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
author keywords: Crassulaceae; topical gel formulation; wound healing; stability study; analytical marker; phenolic compounds
www.frontiersin.org (publisher PDF)
Sources: Web Of Science, ORCID
Added: March 20, 2023
2023 article
Phenolic-rich extract of Nopalea cochenillifera attenuates gastric lesions induced in experimental models through inhibiting oxidative stress, modulating inflammatory markers and a cytoprotective effect
Silva, E. C. S., Guerra, G. C. B., Araujo, E. R. D., Schlamb, J., Silva, V. C., Tavares, E. de A., … Zucolotto, S. M. (2023, February 23). FOOD & FUNCTION, Vol. 2.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
MeSH headings : Rats; Animals; Plant Extracts / chemistry; Rats, Wistar; Stomach Ulcer / chemically induced; Stomach Ulcer / drug therapy; Stomach Ulcer / pathology; Anti-Ulcer Agents / chemistry; Ethanol / chemistry; Indomethacin / adverse effects; Oxidative Stress; Cactaceae; Models, Theoretical; Gastric Mucosa / metabolism
Sources: Web Of Science, ORCID
Added: April 4, 2023
2022 review
Anti-Inflammatory, Antioxidant, and Skin Regenerative Potential of Secondary Metabolites from Plants of the Brassicaceae Family: A Systematic Review of In Vitro and In Vivo Preclinical Evidence (Biological Activities Brassicaceae Skin Diseases)
[Review of ]. ANTIOXIDANTS, 11(7).
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
author keywords: Brassicaceae; inflammation; murine; epithelial cells; cytokines; inflammatory mediators
Sources: ORCID, Web Of Science
Added: July 11, 2022
2022 journal article
Brassinosteroids control the inflammation, oxidative stress and cell migration through the control of mitochondrial function on skin regeneration
LIFE SCIENCES, 307.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
author keywords: Anti-inflammation; Wound healing; Human dermal fibroblasts; Migration; Gene expression; Mitochondrial function
MeSH headings : Brassinosteroids / metabolism; Brassinosteroids / pharmacology; Cell Movement; Fibroblasts / metabolism; Humans; Inflammation / metabolism; Lipopolysaccharides / pharmacology; Mitochondria / metabolism; Nitric Oxide / metabolism; Oxidative Stress; Plant Growth Regulators / metabolism; Plant Growth Regulators / pharmacology; Reactive Oxygen Species / metabolism; Skin
Sources: Web Of Science, ORCID
Added: December 12, 2022
2022 article
Cellular and Molecular Mechanisms of Oxidative Stress in Wound Healing
Goncalves, R. V., Freitas, M. B., & Esposito, D. (2022, June 17). OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, Vol. 2022.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
MeSH headings : Oxidative Stress; Wound Healing
Sources: ORCID, Web Of Science
Added: June 18, 2022
2022 article
Mechanisms, Biomarkers, and Therapeutics Involved in Inflammatory Disorders and Tissue Repair 2021
Goncalves, R. V., Sarandy, M. M., Esposito, D., & Gouveia Peluzio, M. do C. (2022, March 20). OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, Vol. 2022.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
MeSH headings : Biomarkers; Wound Healing
Sources: ORCID, Web Of Science
Added: March 30, 2022
2022 journal article
The First Optimization Process from Cultivation to Flavonoid-Rich Extract from Moringa oleifera Lam. Leaves in Brazil
FOODS, 11(10).
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
author keywords: avonoids; Moringa oleifera; response surface methodology; ultrasound; cultivation; HPLC-ESI-QTRAP-MS/MS
Sources: ORCID, Web Of Science
Added: May 22, 2022
2020 journal article
Editorial: Cosmeceuticals From Medicinal Plants
Frontiers in Pharmacology.
author keywords: cosmeceutials; medicinal plant; anti-inflammatory; acne (acne vulgaris); skin aging
Source: ORCID
Added: August 4, 2020
2020 journal article
Lily steroidal glycoalkaloid promotes early inflammatory resolution in wounded human fibroblasts
Journal of Ethnopharmacology.
author keywords: Steroidal glycoalkaloid; Lilium longiflorum Thunb.; Scratch migration assay; Gene expression; Easter lily; Human dermal fibroblast cells
MeSH headings : Alkaloids / isolation & purification; Alkaloids / pharmacology; Cell Movement / drug effects; Cells, Cultured; Chromatography, Liquid; Fibroblasts / drug effects; Fibroblasts / pathology; Flowers; Gene Expression Regulation / drug effects; Glycosides / isolation & purification; Glycosides / pharmacology; Humans; Inflammation / drug therapy; Inflammation / pathology; Lilium / chemistry; Plant Roots; Wound Healing / drug effects
Source: ORCID
Added: April 11, 2020
2020 journal article
Phenolic content, anti-inflammatory properties, and dermal wound repair properties of industrially processed and non-processed acai from the Brazilian Amazon
Food & Function, 11(6), 4903–4914.
co-author countries:
Belgium 🇧🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
Contributors: J. Xiong n , F. Matta*, M. Grace n , M. Lila n , N. Ward*, M. Felipe-Sotelo *, n
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Arecaceae; Brazil; Food Industry; Fruit; Humans; Mice; Phytotherapy; Plant Extracts / chemistry; Plant Extracts / pharmacology; Polyphenols / chemistry; RAW 264.7 Cells / drug effects; Wound Healing / drug effects
Source: ORCID
Added: June 5, 2020
2020 journal article
What Is the Impact of Depletion of Immunoregulatory Genes on Wound Healing? A Systematic Review of Preclinical Evidence
Oxidative Medicine and Cellular Longevity, 2020, 1–19.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
Ed(s): S. Bekeschus
MeSH headings : Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Immunomodulation / genetics; Skin / metabolism; Wound Healing
Source: ORCID
Added: December 9, 2020
2019 journal article
Alaskan Berry Extracts Promote Dermal Wound Repair Through Modulation of Bioenergetics and Integrin Signaling
FRONTIERS IN PHARMACOLOGY, 10(SEP).
co-author countries:
United States of America 🇺🇸
Contributors: n , J. Overall n , M. Grace n , S. Komarnytsky n & M. Lila n
author keywords: skin regeneration; wound healing; Alaskan berries; integrins; proanthocyanidins; epicatechins
Sources: Web Of Science, ORCID
Added: October 14, 2019
2019 journal article
Anti-inflammatory and wound healing properties of polyphenolic extracts from strawberry and blackberry fruits
FOOD RESEARCH INTERNATIONAL, 121, 453–462.
co-author countries:
Argentina 🇦🇷 United States of America 🇺🇸
Contributors: F. Velde*, n , M. Grace n , M. Pirovani * & M. Lila n
author keywords: Fragaria ananassa; Rubus fruticosus; Anthocyanins; Proanthocyanidins; Cyclooxygenase-2; Interleukin-6; Skin cell migration
MeSH headings : Animals; Anthocyanins / analysis; Anthocyanins / pharmacology; Anti-Inflammatory Agents / analysis; Anti-Inflammatory Agents / pharmacology; Antioxidants / analysis; Antioxidants / pharmacology; Cell Movement / drug effects; Cell Proliferation / drug effects; Cell Survival / drug effects; Chromatography, High Pressure Liquid; Fragaria / chemistry; Fruit / chemistry; Mice; Phytochemicals / analysis; Phytochemicals / pharmacology; Plant Extracts / analysis; Plant Extracts / pharmacology; Polyphenols / analysis; Polyphenols / pharmacology; Proanthocyanidins / analysis; Proanthocyanidins / pharmacology; RAW 264.7 Cells; Reactive Oxygen Species / metabolism; Rubus / chemistry; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: June 24, 2019
2019 journal article
Blueberry polyphenol-protein food ingredients: The impact of spray drying on the in vitro antioxidant activity, anti-inflammatory markers, glucose metabolism and fibroblast migration
Food Chemistry, 280, 187–194.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
Contributors: R. Hoskin n, J. Xiong n , n & M. Lila n
author keywords: Berries; By-products; Drying; Inflammation; Phytochemicals
MeSH headings : Animals; Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / pharmacology; Antioxidants / chemistry; Blueberry Plants / chemistry; Blueberry Plants / metabolism; Cell Line; Cell Movement / drug effects; Cell Survival / drug effects; Cyclooxygenase 2 / metabolism; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Freeze Drying; Glucose / metabolism; Interleukin-1beta / metabolism; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice; Plant Proteins / chemistry; Plant Proteins / pharmacology; Polyphenols / chemistry; Polyphenols / pharmacology; Protein Aggregates; RAW 264.7 Cells; Rats; Reactive Oxygen Species / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: January 28, 2019
2019 journal article
Changes in the bioactive properties of strawberries caused by the storage in oxygen- and carbon dioxide-enriched atmospheres
FOOD SCIENCE & NUTRITION, 7(8), 2527–2536.
co-author countries:
Argentina 🇦🇷 United States of America 🇺🇸
Contributors: F. Velde*, n , J. Overall n , M. Méndez-Galarraga*, M. Grace n , M. Élida Pirovani *, M. Lila n
author keywords: 2; 2-diphenyl-1-picrylhydrazil; cyclooxygenase-2; ferric reducing antioxidant power; human dermal fibroblast migration; interleukin-6; modified atmosphere storage
Sources: Web Of Science, ORCID
Added: August 5, 2019
2019 journal article
Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages
Journal of Animal Science and Biotechnology, 10(1).
co-author countries:
United States of America 🇺🇸
Contributors: K. Walter n, X. Lin n, S. Jacobi*, T. Käser n, n & J. Odle n
author keywords: Arachidonic acid; Cyclooxygenase; Eicosanoid; Eicosapentaenoic acid; Inflammation; Lipid mediator class switch; LPS; Lipoxin; Porcine alveolar macrophage
Sources: Web Of Science, ORCID, Crossref
Added: April 20, 2020
2019 journal article
Simultaneous LC-MS quantification of anthocyanins and non-anthocyanin phenolics from blueberries with widely divergent profiles and biological activities
Food Chemistry, 277, 336–346.
co-author countries:
United States of America 🇺🇸
Contributors: M. Grace n , J. Xiong n , n , M. Ehlenfeldt * & M. Lila n
author keywords: Pink-fruited; Blueberries; LC-IT-TOF-MS; Quantification; Antioxidant; Anti-inflammatory; PCA
MeSH headings : Animals; Anthocyanins / analysis; Anthocyanins / pharmacology; Anti-Inflammatory Agents / analysis; Anti-Inflammatory Agents / pharmacology; Antioxidants / analysis; Antioxidants / pharmacology; Biological Assay; Blueberry Plants / chemistry; Cell Survival / drug effects; Chromatography, Liquid; Color; Flavonoids / analysis; Flavonoids / pharmacology; Flavonols / analysis; Flavonols / pharmacology; Fruit / chemistry; Hydroxybenzoates / analysis; Hydroxybenzoates / pharmacology; Limit of Detection; Mass Spectrometry; Mice; Nitric Oxide / metabolism; Phenols / analysis; Phenols / pharmacology; Plant Extracts / analysis; Plant Extracts / pharmacology; RAW 264.7 Cells; Reactive Oxygen Species / metabolism; Reproducibility of Results; Resveratrol / analysis; Resveratrol / pharmacology
Sources: Web Of Science, ORCID, Crossref
Added: December 17, 2018
2018 journal article
Berries containing anthocyanins with enhanced methylation profiles are more effective at ameliorating high fat diet-induced metabolic damage
FOOD AND CHEMICAL TOXICOLOGY, 111, 445–453.
co-author countries:
United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: Bioactive food components; Polyphenols; Obesity; Diabetes; Bioenergetics; Functional food
MeSH headings : Animal Feed; Animals; Anthocyanins / chemistry; Diet; Diet, High-Fat / adverse effects; Energy Metabolism; Fruit / chemistry; Lipid Metabolism; Male; Metabolic Diseases; Methylation; Mice; Mice, Inbred C57BL; Rubus / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Metabolic recovery from heavy exertion following banana compared to sugar beverage or water only ingestion: A randomized, crossover trial
PLoS One, 13(3).
co-author countries:
United States of America 🇺🇸
MeSH headings : Adult; Beverages; Bicycling / physiology; Cross-Over Studies; Dietary Carbohydrates / administration & dosage; Drinking Behavior / physiology; Eating / physiology; Exercise / physiology; Female; Humans; Male; Middle Aged; Musa; Physical Exertion / drug effects; Physical Exertion / physiology; Recovery of Function / drug effects; Water / administration & dosage; Young Adult
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Dietary long-chain PUFAs enrich porcine alveolar macrophages and alter Prostaglandin E-2 Production Following LPS Challenge
FASEB Journal, 31.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Health modifying regions in the oat (Avena sativa) genome responsible for beneficial effects on immune and gastrointestinal health
FASEB Journal, 31.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Metabolic Effects of Berries with Structurally Diverse Anthocyanins
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18(2).
co-author countries:
United States of America 🇺🇸
Contributors: J. Overall n , S. Bonney n, M. Wilson n, A. Beermann n, M. Grace n , n , M. Lila n , S. Komarnytsky n
author keywords: berry; gut microbiome; obesity; inflammation; functional food
MeSH headings : Animal Feed; Animals; Anthocyanins / chemistry; Anthocyanins / metabolism; Body Composition; Body Weight; Chromatography, High Pressure Liquid; Dietary Supplements; Feces / chemistry; Fruit / metabolism; Gastrointestinal Microbiome; Glucose / metabolism; Humans; Insulin Resistance; Mice; Molecular Structure; Oxygen Consumption
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities
Chinese Journal of Natural Medicines, 15(11), 816–824.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
Contributors: J. Xiong n , M. Grace n , n , S. Komarnytsky n , F. Wang * & M. Lila n
author keywords: Acacia mearnsii; Proanthocyanidins; Anti-inflammatory; alpha-Amylase; alpha-Glucosidase
MeSH headings : Acacia / chemistry; Animals; Anti-Inflammatory Agents / isolation & purification; Anti-Inflammatory Agents / pharmacology; Carbohydrate Metabolism / drug effects; Glycoside Hydrolase Inhibitors / pharmacology; Inflammation / metabolism; Interleukin-1beta / metabolism; Lipopolysaccharides; Macrophages / drug effects; Mice; Nitric Oxide / metabolism; Nitric Oxide Synthase Type II / metabolism; Plant Bark / chemistry; Plant Extracts / chemistry; Plant Extracts / pharmacology; Polyphenols / isolation & purification; Polyphenols / pharmacology; Proanthocyanidins / pharmacology; RAW 264.7 Cells; alpha-Amylases / antagonists & inhibitors; alpha-Glucosidases / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2017 journal article
Structural constraints and importance of caffeic acid moiety for anti-hyperglycemic effects of caffeoylquinic acids from chicory
MOLECULAR NUTRITION & FOOD RESEARCH, 61(9).
co-author countries:
Malaysia 🇲🇾 United States of America 🇺🇸
Contributors: K. Jackson n, T. Rathinasabapathy n , n & S. Komarnytsky n
author keywords: Blood glucose; Cell bioenergetics; Diabetes; Dietary supplementation; Metabolic syndrome
MeSH headings : Animals; Cell Line, Tumor; Chicory / chemistry; Gluconeogenesis / drug effects; Hypoglycemic Agents / pharmacology; MAP Kinase Signaling System; Pharmacogenetics; Phosphatidylinositol 3-Kinases / physiology; Plant Roots / chemistry; Quinic Acid / analogs & derivatives; Quinic Acid / pharmacology; Rats; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Thiazolopyridines Improve Adipocyte Function by Inhibiting 11 Beta-HSD1 Oxoreductase Activity
Journal of Chemistry, 2017, 1–10.
co-author countries:
Malaysia 🇲🇾 United States of America 🇺🇸
Contributors: T. Rathinasabapathy* , K. Palatini Jackson, Y. Thor n, A. Buru *, n , X. Li n , M. Pichika *, A. Hamzah*, S. Komarnytsky n
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2017 journal article
Wild blueberry polyphenol-protein food ingredients produced by three drying methods: Comparative physico-chemical properties, phytochemical content, and stability during storage
FOOD CHEMISTRY, 235, 76–85.
co-author countries:
Brazil 🇧🇷 United States of America 🇺🇸
author keywords: Soy protein isolate; By-products; Spray drying; Phenolics; Shelf life
MeSH headings : Anthocyanins / analysis; Antioxidants; Blueberry Plants / chemistry; Desiccation / methods; Food Handling / methods; Freeze Drying; Phytochemicals; Polyphenols
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Chemical composition, antioxidant and anti-inflammatory properties of pistachio hull extracts
Food Chemistry, 210, 85–95.
co-author countries:
United States of America 🇺🇸
Contributors: M. Grace n , n , M. Timmers n, J. Xiong n , G. Yousef n, S. Komarnytsky n , M. Lila n
author keywords: Anacardic acids; Triterpene acids; Carotenoids; Tocopherols; Polyphenols; Anti-inflammatory
MeSH headings : Animals; Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / isolation & purification; Anti-Inflammatory Agents / pharmacology; Antioxidants / chemistry; Antioxidants / isolation & purification; Antioxidants / pharmacology; Cell Line; Dose-Response Relationship, Drug; Macrophages / drug effects; Macrophages / metabolism; Mice; Pistacia; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Plant Extracts / pharmacology; Reactive Oxygen Species / antagonists & inhibitors; Reactive Oxygen Species / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Formation of whey protein–polyphenol meso-structures as a natural means of creating functional particles
Food & Function, 7(3), 1306–1318.
co-author countries:
Belgium 🇧🇪 United States of America 🇺🇸
MeSH headings : Fruit / chemistry; Hydrogen-Ion Concentration; Particle Size; Plant Extracts / chemistry; Polyphenols / chemistry; Ribes / chemistry; Vaccinium macrocarpon / chemistry; Vitis / chemistry; Whey Proteins / chemistry
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018
2016 journal article
In vitro lipolytic, antioxidant and anti-inflammatory activities of roasted pistachio kernel and skin constituents
Food & Function, 7(10), 4285–4298.
co-author countries:
United States of America 🇺🇸
Contributors: M. Grace n , n , M. Timmers n, J. Xiong n , G. Yousef n, S. Komarnytsky n , M. Lila n
MeSH headings : Animals; Antioxidants; Cell Survival / drug effects; Cooking; Macrophages / drug effects; Macrophages / metabolism; Mice; Phytochemicals; Pistacia / chemistry; RAW 264.7 Cells; Reactive Oxygen Species; Respiratory Burst; Seeds / chemistry
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Phytochemical Characterization and Anti-inflammatory Properties of Acacia mearnsii Leaves
Natural Product Communications, 11(5), 649–653.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
Contributors: J. Xiong n, M. Grace n , n , F. Wang * & M. Lila n
Source: ORCID
Added: July 9, 2020
2016 journal article
Phytochemical characterization and anti-inflammatory properties of Acacia mearnsii leaves
Natural Product Communications, 11(5), 649–653.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Quantitative comparison of phytochemical profile, antioxidant, and anti-inflammatory properties of blackberry fruits adapted to Argentina
JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 47, 82–91.
co-author countries:
Argentina 🇦🇷 United States of America 🇺🇸
Contributors: F. Velde*, M. Grace n , n , M. Pirovani * & M. Lila n
author keywords: Bubo fruticosus; Polyphenols content; Vitamin C; Cyanidin-3-O-glucoside; Proanthocyanidins; Reactive oxygen species; Cyclooxygenase-2; Interleukin-6; Food analysis; Food composition
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
1,25-Dihydroxyvitamin D-3/vitamin D receptor suppresses brown adipocyte differentiation and mitochondrial respiration
EUROPEAN JOURNAL OF NUTRITION, 54(6), 1001–1012.
co-author countries:
United States of America 🇺🇸
author keywords: Vitamin D receptor; Brown adipocyte; UCP1; Mitochondrial respiration
MeSH headings : 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / genetics; Adipocytes, Brown / physiology; Adipocytes, Brown / ultrastructure; Animals; Calcitriol / pharmacology; Calcitriol / physiology; Cell Differentiation / physiology; Energy Metabolism; Gene Expression; Ion Channels / genetics; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria / metabolism; Mitochondrial Proteins / genetics; Obesity / metabolism; Oxygen Consumption / physiology; PPAR gamma / metabolism; RNA, Messenger / analysis; Receptors, Calcitriol / deficiency; Receptors, Calcitriol / genetics; Receptors, Calcitriol / physiology; Signal Transduction; Uncoupling Protein 1; Vitamin D3 24-Hydroxylase / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes
JOURNAL OF FUNCTIONAL FOODS, 15, 396–407.
co-author countries:
United States of America 🇺🇸
Contributors: J. Kellogg n, n , M. Grace n , S. Komarnytsky n & M. Lila n
author keywords: Seaweed; Phlorotannin; Monoglycosyldiacylglycerol; Inflammation; Insulin resistance; Fucus distichus
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Black Currant Anthocyanins Attenuate Weight Gain and Improve Glucose Metabolism in Diet-Induced Obese Mice with Intact, but Not Disrupted, Gut Microbiome
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 63(27), 6172–6180.
co-author countries:
United States of America 🇺🇸
Contributors: n , T. Damsud n, M. Wilson n, M. Grace n , R. Strauch n, X. Li n , M. Lila n , S. Komarnytsky n
author keywords: gastrointestinal tract; gut microbiome; obesity; inflammation; functional food
MeSH headings : Animals; Anthocyanins / administration & dosage; Anthocyanins / chemistry; Fruit / chemistry; Gastrointestinal Microbiome / drug effects; Glucose / metabolism; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity / drug therapy; Obesity / metabolism; Obesity / microbiology; Obesity / physiopathology; Plant Extracts / administration & dosage; Plant Extracts / chemistry; Ribes / chemistry; Weight Gain / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Characterization of Phenolic Compounds and Antioxidant and Antiinflammatory Activities from Mamuyo (Styrax ramirezii Greenm.) Fruit
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 63(48), 10459–10465.
co-author countries:
Mexico 🇲🇽 United States of America 🇺🇸
Contributors: M. Timmers n, J. Guerrero-Medina n, n , M. Grace n , O. Paredes-López *, P. García-Saucedo*, M. Lila n
author keywords: LC-TOF-MS; Styrax ramirezii; antioxidant activity; anti-inflammatory activity; norneolignan
MeSH headings : Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / pharmacology; Antioxidants / chemistry; Antioxidants / pharmacology; Cyclooxygenase 2 / immunology; Fruit / chemistry; Humans; Interleukin-1beta / immunology; Nitric Oxide / immunology; Nitric Oxide Synthase Type II / immunology; Nitric Oxide Synthase Type II / metabolism; Phenols / chemistry; Phenols / pharmacology; Plant Extracts / chemistry; Plant Extracts / pharmacology; Reactive Oxygen Species / metabolism; Styrax / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Compounds leached from quinoa seeds inhibit matrix metalloproteinase activity and intracellular reactive oxygen species
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE, 37(2), 212–221.
co-author countries:
United States of America 🇺🇸
author keywords: ageing; cell culture; chemical analysis; oxidative damage; phytochemistry; phytoecdysteroid
MeSH headings : Cells, Cultured; Chenopodium quinoa / embryology; Chromatography, Liquid; Humans; Mass Spectrometry; Matrix Metalloproteinase 1 / drug effects; Matrix Metalloproteinase 1 / genetics; Monophenol Monooxygenase / antagonists & inhibitors; Protease Inhibitors / pharmacology; Reactive Oxygen Species / metabolism; Seeds / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Hepatoprotective Activity of Easter Lily (Lilium longiflorum Thunb.) Bulb Extracts
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 63(44), 9722–9728.
co-author countries:
United States of America 🇺🇸
author keywords: Lilium longiflorum Thunb; Easter lily; steroidal glycoside; hepatoprotective activity; hypoglycemic activity
MeSH headings : Animals; Cholesterol; Diabetes Mellitus, Type 2 / drug therapy; Diabetes Mellitus, Type 2 / metabolism; Female; Flowers / chemistry; Humans; Lilium / chemistry; Liver / drug effects; Liver / metabolism; Mice; Mice, Inbred C57BL; Molecular Structure; Plant Extracts / administration & dosage; Plant Extracts / chemistry; Protective Agents / administration & dosage; Protective Agents / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Method to harness bioactive secondary metabolites from intact Quinoa seeds with implications for chronic disease prevention
Planta Medica, 81(11).
co-author countries:
United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 21, 2020
2014 journal article
Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 306(10), C918–C930.
co-author countries:
United States of America 🇺🇸
author keywords: brown adipose tissue; brown adipocytes; UCP-1; pattern recognition receptor; inflammation
MeSH headings : Adipocytes / drug effects; Adipocytes / metabolism; Adipocytes / pathology; Adipose Tissue, Brown / drug effects; Adipose Tissue, Brown / metabolism; Adipose Tissue, Brown / pathology; Animals; Cell Line; Cytokines / genetics; Cytokines / metabolism; Diet, High-Fat; Electron Transport / drug effects; Gene Expression Regulation; Inflammation / genetics; Inflammation / metabolism; Inflammation / pathology; Ion Channels / genetics; Ion Channels / metabolism; Isoproterenol / pharmacology; Male; Mice; Mitochondria / drug effects; Mitochondria / metabolism; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Mitogen-Activated Protein Kinases / genetics; Mitogen-Activated Protein Kinases / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; Nod1 Signaling Adaptor Protein / genetics; Nod1 Signaling Adaptor Protein / metabolism; Nod2 Signaling Adaptor Protein / genetics; Nod2 Signaling Adaptor Protein / metabolism; Obesity / genetics; Obesity / metabolism; Obesity / pathology; Promoter Regions, Genetic; RNA, Messenger / genetics; RNA, Messenger / metabolism; Signal Transduction; Toll-Like Receptor 2 / genetics; Toll-Like Receptor 2 / metabolism; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Uncoupling Protein 1
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Bioactive Capacity, Sensory Properties, and Nutritional Analysis of a Shelf Stable Protein-rich Functional Ingredient with Concentrated Fruit and Vegetable Phytoactives
PLANT FOODS FOR HUMAN NUTRITION, 69(4), 372–378.
co-author countries:
United States of America 🇺🇸
Contributors: M. Grace n , G. Yousef n, n , I. Raskin * & M. Lila n
author keywords: Muscadine; Kale; Protein isolate; Inflammatory biomarkers
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use; Brassica / chemistry; Cannabis; Carotenoids / pharmacology; Carotenoids / therapeutic use; Chemokine CCL2 / metabolism; Diet; Dietary Proteins / analysis; Fruit / chemistry; Functional Food / analysis; Glucosinolates / pharmacokinetics; Glucosinolates / pharmacology; Humans; Inflammation / drug therapy; Inflammation / metabolism; Interleukin-6 / metabolism; Mice; Nutritive Value; Plant Preparations / pharmacology; Plant Preparations / therapeutic use; Polyphenols / pharmacology; Polyphenols / therapeutic use; Soybean Proteins; Taste; Vegetables / chemistry; Vitis / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Comparative Analysis of Phenolic Content and Profile, Antioxidant Capacity, and Anti-inflammatory Bioactivity in Wild Alaskan and Commercial Vaccinium Berries
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 62(18), 4007–4017.
co-author countries:
United States of America 🇺🇸
author keywords: Vaccinium vitis-idaea; V. uliginosum; V. macrocarpon; V. angustifolium; phenolics; antioxidant; anti-inflammatory
MeSH headings : Alaska; Animals; Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / pharmacology; Antioxidants / chemistry; Antioxidants / pharmacology; Chromatography, High Pressure Liquid; Fruit / chemistry; Macrophages / drug effects; Macrophages / immunology; Mass Spectrometry; Mice; Phenols / chemistry; Plant Extracts / chemistry; Plant Extracts / pharmacology; Vaccinium / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Cytotoxic Effects of Ellagitannins Isolated from Walnuts in Human Cancer Cells
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 66(8), 1304–1314.
co-author countries:
United States of America 🇺🇸
MeSH headings : 3T3 Cells; Animals; Apoptosis / drug effects; Cell Line, Tumor; Cyclin B1 / metabolism; Cytochromes c / metabolism; Diet; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydrolyzable Tannins / pharmacology; Juglans / chemistry; MCF-7 Cells; Mice; Mice, Nude; Mitochondria / drug effects; Nuts / chemistry; Plant Extracts / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Inhibitory Effects of Wild Blueberry Anthocyanins and Other Flavonoids on Biomarkers of Acute and Chronic Inflammation in Vitro
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 62(29), 7022–7028.
co-author countries:
United States of America 🇺🇸
Contributors: n , A. Chen n, M. Grace n , S. Komarnytsky n & M. Lila n
author keywords: Vaccinium angustifolium; lowbush blueberry; polyphenols; proanthocyanidins; chlorogenic acid
MeSH headings : Acute Disease; Animals; Anthocyanins / pharmacology; Base Sequence; Biomarkers / metabolism; Blueberry Plants / chemistry; Cell Line; Chromatography, High Pressure Liquid; Chronic Disease; DNA Primers; In Vitro Techniques; Inflammation / metabolism; Macrophages / drug effects; Macrophages / metabolism; Mice; Polymerase Chain Reaction
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Effects of Pregnane Glycosides on Food Intake Depend on Stimulation of the Melanocortin Pathway and BDNF in an Animal Model
Journal of Agricultural and Food Chemistry, 61(8), 1841–1849.
co-author countries:
Ukraine 🇺🇦 United States of America 🇺🇸
Contributors: S. Komarnytsky n , n , T. Rathinasabapathy* , A. Poulev* & I. Raskin *
author keywords: appetite; satiety; body weight; milkweed; Asclepias
MeSH headings : Animals; Appetite / drug effects; Asclepias / chemistry; Brain-Derived Neurotrophic Factor / genetics; Brain-Derived Neurotrophic Factor / metabolism; Cell Line, Tumor; Eating / drug effects; Female; Glycosides / administration & dosage; Humans; Male; Melanocortins / metabolism; Models, Animal; Plant Extracts / administration & dosage; Pregnanes / administration & dosage; Rats; Rats, Wistar
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018
2013 journal article
Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells
JOURNAL OF CELLULAR PHYSIOLOGY, 228(5), 1120–1126.
co-author countries:
United States of America 🇺🇸
MeSH headings : 3-Hydroxysteroid Dehydrogenases / antagonists & inhibitors; 3-Hydroxysteroid Dehydrogenases / biosynthesis; Adrenal Cortex Hormones / metabolism; Androstenedione / analogs & derivatives; Animals; Cell Line, Tumor; Cholesterol Side-Chain Cleavage Enzyme / antagonists & inhibitors; Cholesterol Side-Chain Cleavage Enzyme / biosynthesis; Corticosterone / biosynthesis; Corticosterone / metabolism; Cortisone / metabolism; Glycosides / administration & dosage; Humans; Pregnanes / administration & dosage; Progesterone / analogs & derivatives; Progesterone / biosynthesis; Steroid 11-beta-Hydroxylase / antagonists & inhibitors; Steroid 11-beta-Hydroxylase / biosynthesis; Steroid 17-alpha-Hydroxylase / antagonists & inhibitors; Steroid 17-alpha-Hydroxylase / biosynthesis; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Steroidal glycosides from the bulbs of Easter lily (Lilium longiflorum Thunb.) promote dermal fibroblast migration in vitro
JOURNAL OF ETHNOPHARMACOLOGY, 148(2), 433–440.
co-author countries:
Ecuador 🇪🇨 United States of America 🇺🇸
author keywords: Lilium longiflorum Thunb.; Steroidal glycoside; Furostanol saponin; Transforming growth factor beta; Nitric oxide; Wound healing
MeSH headings : 3T3 Cells; Animals; Carbohydrate Sequence; Cell Movement / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Dermis / cytology; Dermis / drug effects; Dermis / metabolism; Ethnopharmacology / methods; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Glycosides / chemistry; Glycosides / pharmacology; Human Umbilical Vein Endothelial Cells; Humans; Lilium / chemistry; Mice; Molecular Sequence Data; Nitric Oxide / metabolism; Plant Extracts / chemistry; Plant Extracts / pharmacology; Plant Roots / chemistry; Skin / cytology; Skin / drug effects; Skin / metabolism; Steroids / chemistry; Steroids / pharmacology; Transforming Growth Factor beta / metabolism; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Modulation of muscle mass and myogenic stem cells with natural products
Planta Medica, 78(11).
Source: Crossref
Added: February 5, 2020
2012 conference paper
Modulation of muscle mass and myogenic stem cells with natural products
Planta Medica, 78(11), 1096–1096.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Akt-Dependent Anabolic Activity of Natural and Synthetic Brassinosteroids in Rat Skeletal Muscle Cells
Journal of Medicinal Chemistry, 54(12), 4057–4066.
co-author countries:
United States of America 🇺🇸
Contributors: * , T. Rathinasabapathy* , A. Poulev*, S. Komarnytsky* & I. Raskin *
MeSH headings : Anabolic Agents / chemical synthesis; Anabolic Agents / chemistry; Anabolic Agents / pharmacology; Animals; Cell Line; Cell Survival / drug effects; Cholestanones / chemical synthesis; Cholestanones / chemistry; Cholestanones / pharmacology; Mice; Muscle, Skeletal / cytology; Muscle, Skeletal / drug effects; Phosphorylation; Proto-Oncogene Proteins c-akt / metabolism; Rats; Stereoisomerism; Structure-Activity Relationship
Sources: Crossref, ORCID, Web Of Science
Added: August 6, 2018
Employment
Updated: November 2nd, 2021 16:49
2016 - present
North Carolina State University North Carolina Agricultural Research Service Raleigh, NC, US
Assistant Professor
Animal Science - Plants for Human Health Institute
Education
Updated: November 2nd, 2021 16:52
2010 - 2012
Rutgers The State University of New Jersey New Brunswick, NJ, US
MBS Drug Discovery & Development
Business School
2007 - 2012
Rutgers University - Douglass Campus New Brunswick, NJ, US
PhD Cell Molecular Biology
Plant Pathology & Biology
