David A. Zaharoff

Focal Cryo-Immunotherapy with Intratumoral IL-12 Prevents Recurrence of Large Murine Tumors

CANCERS, 15(8).

Heparin Affinity-Based IL-4 Delivery to Modulate Macrophage Phenotype and Endothelial Cell Activity In Vitro

ACS APPLIED MATERIALS & INTERFACES, 15(23), 27457–27470.

IDENTIFICATION OF VASOACTIVE INTESTINAL PEPTIDE (VIP)-SPECIFIC SINGLE-CHAIN ANTIBODY FRAGMENTS (SCFVS) VIA YEAST SURFACE DISPLAY

Zaharoff, D., & Nguyen, K. (2022, November). JOURNAL FOR IMMUNOTHERAPY OF CANCER, Vol. 10, pp. A1424–A1425.

Intranasal Delivery of Thermostable Subunit Vaccine for Cross-Reactive Mucosal and Systemic Antibody Responses Against SARS-CoV-2

FRONTIERS IN IMMUNOLOGY, 13.

Raman spectroscopy reveals phenotype switches in breast cancer metastasis

THERANOSTICS, 12(12), 5351–5363.

Construction of heparan sulfate microarray for investigating the binding of specific saccharide sequences to proteins

GLYCOBIOLOGY, 31(3), 188–199.

INJECTABLE CHITOSAN HYDROGEL FOR LOCALIZED DELIVERY OF IMMUNE CHECKPOINT INHIBITORS

Mantooth, S., Zaharoff, D., & Mantooth, S. (2021, November). JOURNAL FOR IMMUNOTHERAPY OF CANCER, Vol. 9, pp. A281–A281.

ONCO-IMMUNOLOGICAL MECHANISMS OF FOCAL ABLATION AND LOCALIZED IL-12 IMMUNOTHERAPY

Vrabel, M., Zaharoff, D., & Mantooth, S. (2021, November). JOURNAL FOR IMMUNOTHERAPY OF CANCER, Vol. 9, pp. A650–A650.

Safety and Pharmacokinetics of Intravesical Chitosan/Interleukin-12 Immunotherapy in Murine Bladders

BLADDER CANCER, 7(4), 427–437.

INTRATUMORAL INTERLEUKIN-12 ADMINISTERED AFTER CRYOABLATION DOES NOT IMPROVE SURVIVAL IN MULTIPLE BILATERAL MURINE MODELS

Vrabel, M., Schulman, J., & Zaharoff, D. (2020, November). JOURNAL FOR IMMUNOTHERAPY OF CANCER, Vol. 8, pp. A277–A278.

Analyzing the effects of instillation volume on intravesical delivery using biphasic solute transport in a deformable geometry

MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA, 36(2), 139–156.

Design of a thrombin resistant human acidic fibroblast growth factor (hFGF1) variant that exhibits enhanced cell proliferation activity

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 518(2), 191–196.

Flow-Encoded Oxygen Control to Track the Time-Dependence of Molecular Changes Induced by Static or Cycling Hypoxia

ANALYTICAL CHEMISTRY, 91(23), 15032–15039.

Molecular mechanisms of heparin-induced modulation of human interleukin 12 bioactivity

Journal of Biological Chemistry, 294(12), 4412–4424.

ULTRASOUND-STIMULATED PHASE-CHANGE CONTRAST AGENTS FOR TRANSEPITHELIAL DELIVERY OF MACROMOLECULES, TOWARD GASTROINTESTINAL DRUG DELIVERY

ULTRASOUND IN MEDICINE AND BIOLOGY, 45(7), 1762–1776.

Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor

Biochemistry and Biophysics Reports, 13, 45–57.

Probing the role of proline-135 on the structure, stability, and cell proliferation activity of human acidic fibroblast growth factor

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 654, 115–125.

Tumor-derived granulocyte colony-stimulating factor diminishes efficacy of breast tumor cell vaccines

BREAST CANCER RESEARCH, 20.

Immunological mechanisms of intravesical chitosan/interleukin-12 immunotherapy against murine bladder cancer

ONCOIMMUNOLOGY, 6(1).

Modulation of Interleukin-12 activity in the presence of heparin

SCIENTIFIC REPORTS, 7.

Strategic Directions in Immunoresponsive Biomaterials in Tissue Engineering INTRODUCTION

Zaharoff, D. A., & Jewell, C. M. (2017, October). TISSUE ENGINEERING PART A, Vol. 23, pp. 1042–1043.

Corrigendum to ‘Controlling chitosan-based encapsulation for protein and vaccine delivery’ [Biomaterials 35 (2014) 4382–4389]

Biomaterials, 73, 308.

Intravesical chitosan/interleukin-12 immunotherapy induces tumor-specific systemic immunity against murine bladder cancer

Cancer Immunology, Immunotherapy, 64(6), 689–696.

Controlling chitosan-based encapsulation for protein and vaccine delivery

Biomaterials, 35(14), 4382–4389.

Efficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tag

Protein Expression and Purification, 102, 76–84.

583 INTRAVESICAL IMMUNOTHERAPY WITH CHITOSAN AND INTERLEUKIN-12 INDUCES SYSTEMIC TUMOR-SPECIFIC IMMUNITY

Journal of Urology, 189(4S).

Nanotheranostics of Circulating Tumor Cells, Infections and Other Pathological Features in Vivo

Molecular Pharmaceutics, 10(3), 813–830.

Role of chitosan co-formulation in enhancing interleukin-12 delivery and antitumor activity

Biomaterials, 34(15), 3828–3836.

The effect of antigen encapsulation in chitosan particles on uptake, activation and presentation by antigen presenting cells

Biomaterials, 34(9), 2359–2369.

In vivo efficacy of a chitosan/IL-12 adjuvant system for protein-based vaccines

Biomaterials, 32(3), 926–932.

Exercise enhances vaccine-induced antigen-specific T cell responses

Vaccine, 26(42), 5407–5415.

Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination

Vaccine, 25(11), 2085–2094.

Chitosan solution enhances the immunoadjuvant properties of GM-CSF

Vaccine, 25(52), 8673–8686.

Electric field-mediated transport of plasmid DNA in tumor interstitium in vivo

Bioelectrochemistry, 71(2), 233–242.

A single molecule detection method for understanding mechanisms of electric field-mediated interstitial transport of genes

Bioelectrochemistry, 69(2), 248–253.

Electric Fields in Tumors Exposed to External Voltage Sources: Implication for Electric Field-Mediated Drug and Gene Delivery

Annals of Biomedical Engineering, 34(10), 1564–1572.

Electric field-mediated enhancement of in vivo transport of plasmid DNA in tumor interstitium

Journal of Biomechanics, 39, S377.

Nonlinear Dependence of Hydraulic Conductivity on Tissue Deformation During Intratumoral Infusion

Annals of Biomedical Engineering, 34(7), 1173–1181.

Effects of pulse strength and pulse duration on in vitro DNA electromobility

Bioelectrochemistry, 62(1), 37–45.