Works (53)

Updated: August 8th, 2023 21:15

2023 journal article

Tizoxanide Antiviral Activity on Dengue Virus Replication

VIRUSES-BASEL, 15(3).

By: K. Yamamoto*, K. Blackburn n, M. Goshe n, D. Brown n, E. Migoswski*, I. Campanhon*, M. Moreira*, D. Ferreira n, M. Soares*

author keywords: antiviral; tizoxanide; dengue virus; virucidal activity
MeSH headings : Chlorocebus aethiops; Animals; Humans; Antiviral Agents / pharmacology; Antiviral Agents / therapeutic use; Vero Cells; Dengue / drug therapy; Dengue Virus / genetics; Proteomics; Virus Replication
Source: Web Of Science
Added: April 17, 2023

2018 journal article

Role of the vacuolar ATPase in the Alphavirus replication cycle

Heliyon, 4(7), e00701.

By: R. Schuchman n, R. Vancini n, A. Piper n, D. Breuer n, M. Ribeiro n, D. Ferreira n, J. Magliocca n, V. Emmerich n, R. Hernandez n, D. Brown n

author keywords: Virology; Cell biology
Source: Crossref
Added: June 6, 2020

2016 journal article

Single-Site Glycoprotein Mutants Inhibit a Late Event in Sindbis Virus Assembly

JOURNAL OF VIROLOGY, 90(18), 8372–8380.

By: J. Magliocca n, R. Vancini n, R. Hernandez n & D. Brown n

MeSH headings : Animals; Cells, Cultured; Cricetinae; Membrane Glycoproteins / genetics; Membrane Glycoproteins / metabolism; Microscopy, Electron; Mutant Proteins / genetics; Mutant Proteins / metabolism; Mutation, Missense; Point Mutation; Sequence Deletion; Sindbis Virus / genetics; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Suppression, Genetic; Temperature; Viral Envelope Proteins / genetics; Viral Envelope Proteins / metabolism; Viral Load; Virion / ultrastructure; Virus Assembly; Virus Cultivation; Virus Release
Source: Web Of Science
Added: August 6, 2018

2016 journal article

The role of the vacuolar ATPase in alphavirus replication.

Molecular Biology of the Cell, 27.

By: R. Schuchman, R. Vancini, A. Piper, D. Breuer, M. Ribeiro, D. Farreira, J. Magliocca, V. Emmerich, R. Hernandez, D. Brown

Source: NC State University Libraries
Added: August 6, 2018

2015 review

Alphavirus Entry into Host Cells

[Review of ]. Molecular basis of viral infection, 129, 33–62.

By: R. Vancini, R. Hernandez & D. Brown

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Live Attenuated Tetravalent Dengue Virus Host Range Vaccine Is Immunogenic in African Green Monkeys following a Single Vaccination

JOURNAL OF VIROLOGY, 88(12), 6729–6742.

By: C. Briggs*, K. Smith*, A. Piper n, E. Huitt*, C. Spears*, M. Quiles*, M. Ribeiro n, M. Thomas*, D. Brown n, R. Hernandez n

MeSH headings : Animals; Antibodies, Viral / immunology; Chlorocebus aethiops; Dengue / immunology; Dengue / prevention & control; Dengue / virology; Dengue Vaccines / administration & dosage; Dengue Vaccines / genetics; Dengue Vaccines / immunology; Dengue Virus / classification; Dengue Virus / genetics; Dengue Virus / immunology; Dengue Virus / physiology; Host Specificity; Humans; Species Specificity; Vaccination; Vaccines, Attenuated / administration & dosage; Vaccines, Attenuated / genetics; Vaccines, Attenuated / immunology; Viral Envelope Proteins / administration & dosage; Viral Envelope Proteins / genetics; Viral Envelope Proteins / immunology
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Alphavirus Genome Delivery Occurs Directly at the Plasma Membrane in a Time- and Temperature-Dependent Process

JOURNAL OF VIROLOGY, 87(8), 4352–4359.

By: R. Vancini n, G. Wang n, D. Ferreira*, R. Hernandez n & D. Brown n

MeSH headings : Animals; Cell Membrane / virology; Cells, Cultured; Cricetinae; Microscopy, Immunoelectron; RNA, Viral / metabolism; Sindbis Virus / physiology; Staining and Labeling / methods; Temperature; Time Factors; Virus Internalization
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Chikungunya Virus Host Range E2 Transmembrane Deletion Mutants Induce Protective Immunity against Challenge in C57BL/6J Mice

JOURNAL OF VIROLOGY, 87(12), 6748–6757.

By: A. Piper n, M. Ribeiro n, K. Smith*, C. Briggs*, E. Huitt*, K. Nanda*, C. Spears*, M. Quiles* ...

MeSH headings : Alphavirus Infections / immunology; Alphavirus Infections / prevention & control; Alphavirus Infections / virology; Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; Cell Line; Chikungunya Fever; Chikungunya virus / genetics; Chikungunya virus / immunology; Chikungunya virus / pathogenicity; Chikungunya virus / physiology; Host Specificity; Humans; Mice; Mice, Inbred C57BL; Mutation; Sequence Deletion; Vaccines, Attenuated / genetics; Vaccines, Attenuated / immunology; Viral Vaccines / genetics; Viral Vaccines / immunology; Virus Replication
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Flavivirus infection from mosquitoes in vitro reveals cell entry at the plasma membrane

VIROLOGY, 435(2), 406–414.

By: R. Vancini n, L. Kramer*, M. Ribeiro n, R. Hernandez n & D. Brown n

author keywords: Flavivirus; Virus entry; Mosquitoes; Electron microscopy
MeSH headings : Animals; Cell Membrane / ultrastructure; Cell Membrane / virology; Chlorocebus aethiops; Culex / virology; Culicidae / virology; Dengue Virus / pathogenicity; Dengue Virus / ultrastructure; Flavivirus / pathogenicity; Microscopy, Electron; Vero Cells / virology; Virus Internalization; West Nile virus / pathogenicity; West Nile virus / ultrastructure
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Conformational Changes in Sindbis Virus Induced by Decreased pH Are Revealed by Small-Angle Neutron Scattering

JOURNAL OF VIROLOGY, 86(4), 1982–1987.

By: L. He*, A. Piper n, F. Meilleur n, R. Hernandez n, W. Heller* & D. Brown n

MeSH headings : Hydrogen-Ion Concentration; RNA, Viral / chemistry; RNA, Viral / genetics; RNA, Viral / metabolism; Scattering, Small Angle; Sindbis Virus / chemistry; Sindbis Virus / genetics; Sindbis Virus / metabolism; Viral Proteins / chemistry; Viral Proteins / genetics; Virion / chemistry; Virion / genetics; Virion / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Infection of cells by alphaviruses

Viral Molecular Machines, 726, 181–199.

By: D. Brown & R. Hernandez

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Testing of Novel Dengue Virus 2 Vaccines in African Green Monkeys: Safety, Immunogenicity, and Efficacy

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 87(4), 743–753.

By: K. Smith, K. Nanda, V. McCarl, C. Spears, A. Piper*, M. Ribeiro, M. Quiles, C. Briggs ...

MeSH headings : Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; Cells, Cultured; Chlorocebus aethiops; Dengue / immunology; Dengue / prevention & control; Dengue / virology; Dengue Vaccines / adverse effects; Dengue Vaccines / genetics; Dengue Vaccines / immunology; Dengue Vaccines / therapeutic use; Dengue Virus / genetics; Dengue Virus / immunology; Immunization; Neutralization Tests; Viral Envelope Proteins / genetics; Viral Envelope Proteins / immunology; Viral Plaque Assay
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Alphavirus adsorption to mosquito cells as viewed by freeze fracture immunolabeling

VIROLOGY, 415(2), 132–140.

By: J. Kononchik n, R. Vancini n & D. Brown n

author keywords: Alphavirus; Cell penetration; Insect cells; Freeze-fracture; Electron microscopy
MeSH headings : Adsorption; Alphavirus / chemistry; Alphavirus / physiology; Alphavirus / ultrastructure; Animals; Cell Membrane / chemistry; Cell Membrane / ultrastructure; Cell Membrane / virology; Cells, Cultured; Culicidae / virology; Freeze Fracturing / methods; Immunohistochemistry / methods
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Role of the Vacuolar-ATPase in Sindbis Virus Infection

JOURNAL OF VIROLOGY, 85(3), 1257–1266.

By: S. Hunt n, R. Hernandez n & D. Brown n

MeSH headings : Animals; Cells, Cultured; Cricetinae; Enzyme Inhibitors / metabolism; Host-Pathogen Interactions; Macrolides / metabolism; Sindbis Virus / physiology; Vacuolar Proton-Translocating ATPases / metabolism; Virus Internalization; Virus Replication
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Structural mutants of dengue virus 2 transmembrane domains exhibit host-range phenotype

VIROLOGY JOURNAL, 8.

By: K. Smith, K. Nanda, C. Spears, M. Ribeiro n, R. Vancini n, A. Piper n, G. Thomas*, M. Thomas, D. Brown n, R. Hernandez n

MeSH headings : Aedes; Amino Acid Sequence; Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; Cell Line; Dengue Virus / genetics; Dengue Virus / immunology; Dengue Virus / pathogenicity; Dengue Virus / physiology; Host Specificity; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Sequence Data; Mutant Proteins / genetics; Mutant Proteins / immunology; Mutant Proteins / metabolism; Sequence Deletion; Viral Envelope Proteins / genetics; Viral Envelope Proteins / immunology; Viral Envelope Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Growth and Maintenance of Baby Hamster Kidney (BHK) Cells

Current Protocols in Microbiology, 17(1), A.4H.1-A.4H.7.

By: R. Hernandez n & D. Brown n

MeSH headings : Animals; Cell Culture Techniques; Cell Line; Cricetinae; Culture Media / chemistry; Fibroblasts; Kidney / cytology; Mesocricetus; Sindbis Virus / growth & development; Virus Cultivation / methods
Source: Crossref
Added: August 14, 2021

2010 journal article

Growth and Maintenance of Chick Embryo Fibroblasts (CEF)

Current Protocols in Microbiology, 17(1), A.4I.1-A.4I.8.

By: R. Hernandez n & D. Brown n

MeSH headings : Animals; Cell Culture Techniques; Cells, Cultured; Chick Embryo; Culture Media / chemistry; Fibroblasts
Source: Crossref
Added: August 16, 2021

2010 journal article

Growth and Maintenance of Mosquito Cell Lines

Current Protocols in Microbiology, 17(1), A.4J.1-A.4J.8.

By: R. Hernandez n & D. Brown n

MeSH headings : Animals; Cell Culture Techniques / methods; Cell Line; Culicidae; Culture Media / chemistry
Source: Crossref
Added: October 9, 2021

2010 journal article

Insect response to alphavirus infection-Establishment of alphavirus persistence in insect cells involves inhibition of viral polyprotein cleavage

VIRUS RESEARCH, 150(1-2), 73–84.

By: U. Mudiganti n, R. Hernandez n & D. Brown n

author keywords: Arbovirus; Sindbis; Insect cells; Microarray; Persistent infection
MeSH headings : Alphavirus / pathogenicity; Alphavirus / physiology; Animals; Cell Line; Drosophila; Polyproteins / metabolism; Viral Proteins / metabolism; Virus Replication
Source: Web Of Science
Added: August 6, 2018

2010 journal article

The Structure of Sindbis Virus Produced from Vertebrate and Invertebrate Hosts as Determined by Small-Angle Neutron Scattering

JOURNAL OF VIROLOGY, 84(10), 5270–5276.

MeSH headings : Animals; Cell Line; Cricetinae; Culicidae; Scattering, Small Angle; Sindbis Virus / chemistry; Sindbis Virus / growth & development; Virion / chemistry; Virion / isolation & purification
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

A high capacity Alphavirus heterologous gene delivery system

VIROLOGY, 390(2), 368–373.

By: K. Nanda n, R. Vancini n, M. Ribeiro n, D. Brown n & R. Hernandez n

author keywords: Alphavirus; Gene delivery; Morphological variants
MeSH headings : Animals; Cell Line; Cricetinae; Culicidae; Gene Transfer Techniques; Genetic Vectors; Microscopy, Electron, Transmission; Mutation, Missense; Sindbis Virus / genetics; Viral Proteins / genetics; Virion / ultrastructure
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Differential Incorporation of Cholesterol by Sindbis Virus Grown in Mammalian or Insect Cells

JOURNAL OF VIROLOGY, 83(18), 9113–9121.

By: A. Hafer n, R. Whittlesey n, D. Brown n & R. Hernandez n

MeSH headings : Alphavirus Infections / etiology; Animals; Cell Line; Cell Membrane / chemistry; Cholesterol / analysis; Cholesterol / deficiency; Cholesterol / metabolism; Insecta; Lipids / analysis; Mammals; Mass Spectrometry; Sindbis Virus / metabolism; Sindbis Virus / pathogenicity
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Helical virus particles formed from morphological subunits of a membrane containing icosahedral virus

VIROLOGY, 385(2), 285–293.

By: J. Kononchik n, S. Nelson*, R. Hernandez n & D. Brown n

author keywords: Sindbis virus; Virus assembly; Protein interactions; Morphological variants; Helix symmetry; Icosahedral symmetry
MeSH headings : Animals; Cricetinae; Furin / metabolism; Membrane Glycoproteins / genetics; Membrane Glycoproteins / physiology; Microscopy, Electron, Scanning; Mutation; Sindbis Virus / chemistry; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Viral Proteins / metabolism; Virion / chemistry; Virus Assembly
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Construction and characterization of mutant Dengue2 virus vaccine candidates displaying a host-range phenotype

Vaccine.

By: K. Smith, K. Nanda, C. Slominski, R. Hernandez, D. Brown & M. Thomas

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Sindbis virus conformational changes induced by a neutralizing anti-E1 monoclonal antibody

JOURNAL OF VIROLOGY, 82(12), 5750–5760.

By: R. Hernandez n, A. Paredes* & D. Brown n

MeSH headings : Animals; Antibodies, Monoclonal / pharmacology; Cricetinae; Epitopes; Hydrogen-Ion Concentration; Immunoglobulin Fab Fragments / immunology; Kidney / cytology; Membrane Glycoproteins / immunology; Neutralization Tests; Peptide Mapping; Protein Binding; Protein Conformation; Sindbis Virus / chemistry; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Viral Envelope Proteins / immunology; Virion / physiology; Virion / ultrastructure
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Infection of cells by Sindbis virus at low temperature

Virology, 362(2), 461–467.

By: G. Wang n, R. Hernandez n, keith & D. Brown n

MeSH headings : Animals; Cell Fusion; Cell Line; Cricetinae; Endocytosis; Microscopy, Immunoelectron; Neutral Red / metabolism; Sindbis Virus / physiology; Temperature; Time Factors; Viral Plaque Assay; Virus Internalization
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2007 journal article

Location and role of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins

JOURNAL OF VIROLOGY, 81(12), 6231–6240.

By: C. Whitehurst n, E. Soderblom n, M. West n, R. Hernandez n, M. Goshe n & D. Brown n

MeSH headings : Amino Acid Sequence; Animals; Capsid / chemistry; Cell Line; Chromatography, Liquid; Cricetinae; Cysteine / chemistry; Disulfides / chemistry; Iodoacetamide / pharmacology; Mass Spectrometry; Membrane Glycoproteins / chemistry; Molecular Sequence Data; Mutation; Protein Conformation; Viral Envelope Proteins / chemistry
Source: Web Of Science
Added: August 6, 2018

2006 journal article

A colorimetric assay for viral agents that produce cytopathic effects

Journal of Virological Methods, 135(1), 56–65.

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

A colorimetric assay for viral agents that produce cytopathic effects

Journal of Virological Methods, 135(1), 56–65.

By: C. Heldt n, R. Hernandez n, U. Mudiganti n, P. Gurgel, D. Brown n & R. Carbonell n

author keywords: MTT; TCID50; plaque assay; parvovirus; Sindbis virus
MeSH headings : Animals; Cell Line; Colorimetry / methods; Cricetinae; Cytopathogenic Effect, Viral; Dogs; Formazans / metabolism; Humans; Minute Virus of Mice / pathogenicity; Parvovirus, Canine / pathogenicity; Parvovirus, Porcine / pathogenicity; Reproducibility of Results; Sindbis Virus / pathogenicity; Swine; Tetrazolium Salts / metabolism; Viral Plaque Assay; Viruses / pathogenicity
Source: Crossref
Added: August 28, 2020

2006 journal article

Mutations in the endodomain of Sindbis virus glycoprotein E2 define sequences critical for virus assembly

JOURNAL OF VIROLOGY, 80(9), 4458–4468.

By: J. West n, R. Hernandez n, D. Ferreira n & D. Brown n

MeSH headings : Amino Acid Sequence; Animals; Capsid Proteins / genetics; Capsid Proteins / metabolism; Cell Line; Cricetinae; Gene Deletion; Microscopy, Electron, Transmission; Molecular Sequence Data; Mutation / genetics; Protein Structure, Tertiary; Sequence Alignment; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Tyrosine / genetics; Tyrosine / metabolism; Viral Envelope Proteins / chemistry; Viral Envelope Proteins / genetics; Viral Envelope Proteins / metabolism; Virus Assembly
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Role of a conserved tripeptide in the endodomain of Sindbis virus glycoprotein E2 in virus assembly and function

JOURNAL OF GENERAL VIROLOGY, 87, 657–664.

By: J. West n & D. Brown n

MeSH headings : Acids; Amino Acid Sequence; Animals; Cell Fusion; Cell Line; Cricetinae; Molecular Sequence Data; Protein Structure, Tertiary / genetics; Protein Structure, Tertiary / physiology; Sindbis Virus / pathogenicity; Sindbis Virus / physiology; Viral Envelope Proteins / chemistry; Viral Envelope Proteins / genetics; Viral Envelope Proteins / physiology; Virulence; Virus Assembly
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Sindbis virus infection of two model insect cell systems - A comparative study

Virus Research, 122(1-2), 28–34.

By: U. Mudiganti n, R. Hernandez n, D. Ferreira n & D. Brown n

MeSH headings : Animals; Cell Line; Cell Shape; Cell Survival; Culicidae; Cytopathogenic Effect, Viral; Drosophila; Microscopy, Electron, Transmission; Sindbis Virus / growth & development; Viral Plaque Assay
Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Single and multiple deletions in the transmembrane domain of the Sindbis virus E2 glycoprotein identify a region critical for normal virus growth

VIROLOGY, 347(1), 199–207.

author keywords: Sindis virus; E2 glycoprotein; transmembrane domain; virus assembly; compensatory mutations
MeSH headings : Amino Acid Sequence; Animals; Cell Line; Cricetinae; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Deletion; Sindbis Virus / genetics; Sindbis Virus / growth & development; Sindbis Virus / physiology; Viral Envelope Proteins / chemistry; Viral Envelope Proteins / genetics; Virus Replication / genetics
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Structural characterization of the E2 glycoprotein from Sindbis by lysine biotinylation and LC-MS/MS

VIROLOGY, 348(1), 216–223.

By: J. Sharp, S. Nelson, D. Brown* & K. Tomer

author keywords: Sindbis; mass spectrometry; surface labeling; Alphavirus; glycoprotein
MeSH headings : Amino Acid Sequence; Animals; Biotin / metabolism; Cell Line; Cricetinae; Lysine / metabolism; Mass Spectrometry / methods; Microscopy, Electron, Transmission; Molecular Sequence Data; Protein Structure, Quaternary; Sindbis Virus / chemistry; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Staining and Labeling / methods; Viral Envelope Proteins / chemistry; Viral Envelope Proteins / ultrastructure; Viral Plaque Assay; Virion / chemistry; Virion / ultrastructure
Source: Web Of Science
Added: August 6, 2018

2005 journal article

In vivo processing and isolation of furin protease-sensitive alphavirus glycoproteins: a new technique for producing mutations in virus assembly

VIROLOGY, 332(2), 629–639.

By: S. Nelson n, R. Hernandez n, D. Ferreira n & D. Brown n

author keywords: alphavirus; Sindbis; membrane glycoproteins; form protease; virus assembly
MeSH headings : Animals; Capsid Proteins / genetics; Cell Line; Cricetinae; Dithiothreitol / pharmacology; Ethylmaleimide / pharmacology; Furin / pharmacology; Kidney; Mutagenesis, Site-Directed; Mutagens; Sindbis Virus / drug effects; Sindbis Virus / genetics; Sindbis Virus / isolation & purification; Viral Envelope Proteins / genetics; Viral Structural Proteins / genetics
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Single amino acid insertions at the junction of the Sindbis virus e2 transmembrane domain and endodomain disrupt virus envelopment and alter infectivity

Journal of Virology, 79(12), 7682–7697.

By: R. Hernandez, D. Ferreira, C. Sinodis, K. Litton & D. Brown

Source: NC State University Libraries
Added: August 6, 2018

2005 chapter

Trust-Based Secure Workflow Path Construction

In B. Benatallah, F. Casati, & P. Traverso (Eds.), Service-Oriented Computing – ICSOC 2007 (pp. 382–395).

By: M. Altunay n, D. Brown n, G. Byrd n & R. Dean n

Contriutors: M. Altunay n, D. Brown n, G. Byrd n & R. Dean n

Ed(s): B. Benatallah, F. Casati & P. Traverso

Sources: Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion

Virology, 324(2), 373–386.

By: A. Paredes, D. Ferreira, M. Horton, A. Saad, H. Tsuruta, R. Johnston, W. Klimstra, K. Ryman ...

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion

Virology, 324(2), 373–386.

By: A. Paredes*, D. Ferreira n, M. Horton n, A. Saad*, H. Tsuruta*, R. Johnston*, W. Klimstra*, K. Ryman* ...

author keywords: Sindbis virus; electron cryo-microscopy; pH conditions; structure; infection; membrane fusion
MeSH headings : Animals; Cell Fusion; Cell Line; Cricetinae; Cryoelectron Microscopy; Hydrogen-Ion Concentration; Membrane Fusion; Microscopy, Electron; Protein Conformation; Sindbis Virus / chemistry; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Viral Envelope Proteins / chemistry; Viral Envelope Proteins / ultrastructure; Virion / chemistry; Virion / physiology; Virus Replication
Source: Crossref
Added: October 9, 2021

2004 journal article

Rapid preparative purification of West Nile and Sindbis virus PCR products utilizing a microbore anion-exchange column

Journal of Virological Methods, 120(2), 141–149.

By: R. Hernandez, S. Nelson, J. Salm, D. Brown & A. Alpert

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Rapid preparative purification of West Nile and Sindbis virus PCR products utilizing a microbore anion-exchange column

Journal of Virological Methods, 120(2), 141–149.

By: R. Hernandez n, S. Nelson n, J. Salm n, D. Brown n & A. Alpert

author keywords: Sindbis virus; West Nile virus; PCR products; preparative anion-exchange HPLC purification
MeSH headings : Anions / analysis; Anions / isolation & purification; Chromatography, High Pressure Liquid; DNA, Viral / analysis; DNA, Viral / isolation & purification; Polymerase Chain Reaction / methods; Sindbis Virus / genetics; Sindbis Virus / isolation & purification; Time Factors; Virology / methods; West Nile virus / genetics; West Nile virus / isolation & purification
Source: Crossref
Added: October 9, 2021

2003 journal article

Deletions in the transmembrane domain of a Sindbis virus glycoprotein alter virus infectivity, stability, and host range

JOURNAL OF VIROLOGY, 77(23), 12710–12719.

By: R. Hernandez n, C. Sinodis n, M. Horton n, D. Ferreira n, C. Yang n & D. Brown n

MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cricetinae; DNA Primers; Lipid Bilayers; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Sequence Deletion; Sequence Homology, Amino Acid; Sindbis Virus / genetics; Sindbis Virus / physiology; Virus Assembly
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Morphological variants of Sindbis virus produced by a mutation in the capsid protein

VIROLOGY, 307(1), 54–66.

By: D. Ferreira, R. Hernandez*, M. Horton & D. Brown*

MeSH headings : Animals; Capsid Proteins / genetics; Cell Line; Cricetinae; Kidney; Microscopy, Electron; Mutation; RNA, Viral / genetics; Sindbis Virus / genetics; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Transcription, Genetic; Transfection; Viral Plaque Assay
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Exposure to low pH is not required for penetration of mosquito cells by Sindbis virus

JOURNAL OF VIROLOGY, 75(4), 2010–2013.

By: R. Hernandez n, T. Luo n & D. Brown n

MeSH headings : Aedes / virology; Ammonium Chloride / pharmacology; Animals; Cells, Cultured; Chloroquine / pharmacology; Hydrogen-Ion Concentration; Sindbis Virus / drug effects; Sindbis Virus / physiology; Virus Replication / drug effects
Source: Web Of Science
Added: August 6, 2018

2001 journal article

FTIR and resonance Raman studies of nitric oxide binding to H93G cavity mutants of myoglobin

BIOCHEMISTRY, 40(49), 15047–15056.

By: M. Thomas n, D. Brown n, S. Franzen n & S. Boxer n

MeSH headings : Animals; Binding Sites; Enzyme Inhibitors / metabolism; Free Radical Scavengers / metabolism; Imidazoles / metabolism; Molecular Structure; Mutation; Myoglobin / genetics; Myoglobin / metabolism; Nitric Oxide / metabolism; Protein Binding; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman
Sources: Web Of Science, ORCID
Added: August 6, 2018

2001 journal article

Locations of carbohydrate sites on alphavirus glycoproteins show that E1 forms an icosahedral scaffold

CELL, 105(1), 127–136.

By: S. Pletnev*, W. Zhang*, S. Mukhopadhyay*, B. Fisher*, R. Hernandez n, D. Brown n, T. Baker*, M. Rossmann*, R. Kuhn*

MeSH headings : Alphavirus / chemistry; Alphavirus / genetics; Alphavirus / ultrastructure; Amino Acid Motifs / genetics; Animals; Binding Sites / genetics; Carbohydrates / chemistry; Cell Line; Cricetinae; Cryoelectron Microscopy; Encephalitis Viruses, Tick-Borne / chemistry; Glycosylation; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / genetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Ross River virus / chemistry; Sindbis Virus / chemistry; Sindbis Virus / ultrastructure; Viral Envelope Proteins / chemistry; Viral Envelope Proteins / genetics; Viral Fusion Proteins / chemistry; Viral Fusion Proteins / genetics
Source: Web Of Science
Added: August 6, 2018

2000 journal article

A single deletion in the membrane-proximal region of the Sindbis virus glycoprotein E2 endodomain blocks virus assembly

JOURNAL OF VIROLOGY, 74(9), 4220–4228.

By: R. Hernandez n, H. Lee*, C. Nelson n & D. Brown n

MeSH headings : Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Cell Line; Cell Membrane / metabolism; Cricetinae; Cytoplasm / metabolism; Humans; Intracellular Fluid / metabolism; Molecular Sequence Data; Mutagenesis; Nucleocapsid / metabolism; Sindbis Virus / genetics; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Viral Envelope Proteins / genetics; Viral Envelope Proteins / metabolism; Viral Envelope Proteins / physiology; Viral Structural Proteins / metabolism; Virus Assembly / physiology
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Sindbis virus glycoprotein E1 is divided into two discrete domains at amino acid 129 by disulfide bridge connections

JOURNAL OF VIROLOGY, 74(19), 9313–9316.

By: B. Phinney n & D. Brown n

MeSH headings : Amino Acid Sequence; Membrane Glycoproteins / chemistry; Molecular Sequence Data; Sindbis Virus / chemistry; Sulfides; Viral Envelope Proteins / chemistry
Source: Web Of Science
Added: August 6, 2018

2000 journal article

The surface conformation of sindbis virus glycoproteins E1 and E2 at neutral and low pH, as determined by mass spectrometry-based mapping

JOURNAL OF VIROLOGY, 74(12), 5667–5678.

By: B. Phinney n, K. Blackburn* & D. Brown n

MeSH headings : Capsid / chemistry; Capsid / metabolism; Disulfides / metabolism; Hydrogen-Ion Concentration; Iodine Radioisotopes / metabolism; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / metabolism; Pepsin A / metabolism; Peptide Fragments / chemistry; Peptide Fragments / metabolism; Protein Binding; Protein Structure, Tertiary; Serine Endopeptidases / metabolism; Silver Staining; Sindbis Virus; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Properties; Trypsin / metabolism; Tyrosine / metabolism; Viral Envelope Proteins / chemistry; Viral Envelope Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Comparison of Sindbis virus-induced pathology in mosquito and vertebrate cell cultures

VIROLOGY, 240(2), 193–201.

By: A. Karpf* & D. Brown*

MeSH headings : Animals; Apoptosis / genetics; Cell Culture Techniques; Cell Cycle; Cricetinae; Culicidae / cytology; Culicidae / virology; Cytopathogenic Effect, Viral; Flow Cytometry; Sindbis Virus / pathogenicity; Sindbis Virus / ultrastructure
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Laser assisted soldering: Microdroplet accumulation with a microjet device

Lasers in Surgery and Medicine, 23(4), 213–220.

By: E. Chan*, Q. Lu*, B. Bell*, M. Motamedi*, C. Frederickson*, D. Brown n, I. Kovach*, A. Welch*

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Superinfection exclusion of alphaviruses in three mosquito cell lines persistently infected with sindbis virus

Journal of Virology, 71(9), 7119–7123.

By: A. Karpf, E. Lenches, E. Strauss, J. Strauss & D. Brown

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

The formation of intramolecular disulfide bridges is required for induction of the Sindbis virus mutant TS23 phenotype

Journal of Virology, 71(10), 7696–7703.

By: M. Carleton & D. Brown

Source: NC State University Libraries
Added: August 6, 2018