Doug Snider

College of Veterinary Medicine

Works (3)

Updated: April 24th, 2025 08:37

2025 article

Comparison of histochemical methods for the analysis of eosinophils and mast cells using a porcine model of eosinophilic esophagitis

Snider, D. B., Meyerholz, D. K., Dellon, E. S., Cortes, L. M., Karri, A., Blikslager, A. T., … Cruse, G. (2025, March 19). Frontiers in Veterinary Science, Vol. 12.

By: D. Snider n, D. Meyerholz *, E. Dellon *, L. Cortes n, A. Karri n, A. Blikslager n , S. Laster n, T. Käser n , G. Cruse n 

author keywords: eosinophils; histochemical analysis; porcine (pig) model; eosinophilic esophagitis; mast cell (MC); allergy
topics (OpenAlex): Eosinophilic Esophagitis; Food Allergy and Anaphylaxis Research; Eosinophilic Disorders and Syndromes
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Sources: Web Of Science, NC State University Libraries
Added: April 14, 2025

2022 article

Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis

Cortes, L. M., Brodsky, D., Chen, C., Pridgen, T., Odle, J., Snider, D. B., … Käser, T. (2022, November 14). Frontiers in Allergy, Vol. 3.

By: L. Cortes n, D. Brodsky n, C. Chen, T. Pridgen n, J. Odle n , D. Snider n, G. Cruse n , A. Putikova* ...

author keywords: pig; food allergy; animal model; immunology; gastrointestinal; eosinophilic esophagitis
topics (OpenAlex): Eosinophilic Esophagitis; Eosinophilic Disorders and Syndromes; Food Allergy and Anaphylaxis Research
TL;DR: Swine is established as a relevant large animal model for translational biomedical research in EoE with the potential to facilitate development of therapeutics and it is demonstrated that the sensitization and oral challenge protocol not only induces the underlying immune markers but also the micro- and macro-pathological hallmarks of human EiE. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: September 25, 2023

2021 article

Targeting KIT by frameshifting mRNA transcripts as a therapeutic strategy for aggressive mast cell neoplasms

Snider, D. B., Arthur, G. K., Falduto, G. H., Olivera, A., Ehrhardt-Humbert, L. C., Smith, E., … Cruse, G. (2021, August 8). Molecular Therapy, Vol. 1, pp. 295–310.

By: D. Snider n, G. Arthur n, G. Falduto *, A. Olivera *, L. Ehrhardt-Humbert n, E. Smith n, C. Smith n, D. Metcalfe *, G. Cruse n 

Contributors: D. Snider n, G. Arthur n, G. Falduto *, A. Olivera *, L. Ehrhardt-Humbert n, E. Smith n, C. Smith n, D. Metcalfe *, G. Cruse n 

MeSH headings : Humans; Mast Cells / metabolism; Mast Cells / pathology; Mastocytosis / genetics; Mastocytosis / pathology; Mastocytosis / therapy; Proto-Oncogene Proteins c-kit / genetics; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptor Protein-Tyrosine Kinases / metabolism
topics (OpenAlex): Mast cells and histamine; Polyamine Metabolism and Applications; Eosinophilic Disorders and Syndromes; Monoclonal and Polyclonal Antibodies Research
TL;DR: It is proposed that the innovative approach, which employs well-tolerated, chemically stable oligonucleotides to target KIT expression through unconventional pathways, has potential as a KIT-targeted therapeutic alone, or in combination with agents thattarget KIT signaling, in the treatment of K IT-associated malignancies. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 7, 2022

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