David C Dorman

Hazard classification of manganese salts based on animal neurotoxicity data: case study for specific target organ toxicity – repeated exposure (STOT-RE)

Dorman, D. C., McGough, D., Aschner, M., Levy, L., & Gross, P. (2025, April 27). Journal of Toxicology and Environmental Health Part B, Vol. 4.

A Systematic Review and Meta-Analysis of the Efficacy and Safety of Rasagiline or Pramipexole in the Treatment of Early Parkinson’s Disease

Seppänen, P., Forsberg, M. M., Tiihonen, M., Laitinen, H., Beal, S., & Dorman, D. C. (2024, January 16). Parkinson s Disease.

A Systematic Review of the Efficacy of Compression Wraps as an Anxiolytic in Domesticated Dogs

Mathis, S., Schoolfield, S., Gross, P., Gruen, M., & Dorman, D. C. (2024, November 28). Animals, Vol. 14.

Pharmacologic interventions for the treatment of equine herpesvirus-1 in domesticated horses: A systematic review

Goehring, L., Dorman, D. C., Osterrieder, K., Burgess, B. A., Dougherty, K., Gross, P., … Lunn, D. P. (2024, February 21). Journal of Veterinary Internal Medicine, Vol. 2.

Updated ACVIM consensus statement on equine herpesvirus-1

Lunn, D. P., Burgess, B. A., Dorman, D. C., Goehring, L. S., Gross, P., Osterrieder, K., … Hussey, G. S. (2024, March 18). Journal of Veterinary Internal Medicine, Vol. 3.

Phthalates and polycystic ovary syndrome – Systematic literature review

Neuvonen, R., Huovinen, M., Dorman, D. C., Laitinen, H., & Sahlman, H. (2023, September 21). Reproductive Toxicology.

Relationship between equine herpesvirus-1 viremia and abortion or equine herpesvirus myeloencephalopathy in domesticated horses: A systematic review

Soboll-Hussey, G., Dorman, D. C., Burgess, B. A., Goehring, L., Gross, P., Neinast, C., … Lunn, D. P. (2023, December 9). Journal of Veterinary Internal Medicine, Vol. 12.

The Role of Oxidative Stress in Manganese Neurotoxicity: A Literature Review Focused on Contributions Made by Professor Michael Aschner

Dorman, D. C. (2023, July 28). Biomolecules.

Vaccination for the prevention of equine herpesvirus-1 disease in domesticated horses: A systematic review and meta-analysis

Osterrieder, K., Dorman, D. C., Burgess, B. A., Goehring, L. S., Gross, P., Neinast, C., … Lunn, D. P. (2023, November 6). Journal of Veterinary Internal Medicine, Vol. 11.

Viremia and nasal shedding for the diagnosis of equine herpesvirus-1 infection in domesticated horses

Pusterla, N., Dorman, D. C., Burgess, B. A., Goehring, L., Gross, M., Osterrieder, K., … Lunn, D. P. (2023, December 9). Journal of Veterinary Internal Medicine.

The Current State of Veterinary Toxicology Education at AAVMC Member Veterinary Schools

Dorman, D. C., Poppenga, R. H., & Schoenfeld-Tacher, R. M. (2022, November 22). Veterinary Sciences, Vol. 9.

Why Indoor Chemistry Matters: A National Academies Consensus Report

Habre, R., Dorman, D. C., Abbatt, J., Bahnfleth, W. P., Carter, E., Farmer, D., … Harries, M. E. (2022, July 14). Environmental Science & Technology.

Effect of Delivery Format on Student Outcomes and Perceptions of a Veterinary Medicine Course: Synchronous Versus Asynchronous Learning

Schoenfeld-Tacher, R. M., & Dorman, D. C. (2021, January 20). Veterinary Sciences, Vol. 8, p. 13.

Training with Multiple Structurally Related Odorants Fails to Improve Generalization of Ammonium Nitrate Detection in Domesticated Dogs (Canis familiaris)

Dorman, D. C., Foster, M. L., & Lazarowski, L. (2021, January 16). Animals.

Language Consideration and Methodological Transparency in “Systematic” Reviews of Animal Toxicity Studies

Alpi, K. M., Vo, T. A., & Dorman, D. C. (2019, February 21). International Journal of Toxicology.

Use of Nasal Pathology in the Derivation of Inhalation Toxicity Values for Hydrogen Sulfide

Dorman, D. C. (2019, October 30). Toxicologic Pathology.

A pilot study documenting increased thrombin generation following abrupt withdrawal of heparin therapy in healthy dogs

Journal of Veterinary Emergency and Critical Care, 28(6), 518–526.

Carcinogenicity of some nitrobenzenes and other industrial chemicals

The Lancet Oncology, 19(12), e681–e682.

Comparing Item Performance on Three- Versus Four-Option Multiple Choice Questions in a Veterinary Toxicology Course

Veterinary Sciences, 5(2), 55.

Polybrominated diphenyl ether (PBDE) neurotoxicity: a systematic review and meta-analysis of animal evidence

Dorman, D. C., Chiu, W., Hales, B. F., Hauser, R., Johnson, K. J., Mantus, E., … Waters, K. M. (2018, May 19). Journal of Toxicology and Environmental Health Part B.

Student Engagement with Rubrics to Promote Enhanced Written Communication of Health Information

Medical Science Educator, 28(4), 591–596.

Systematic reviews and meta-analyses of human and animal evidence of prenatal diethylhexyl phthalate exposure and changes in male anogenital distance

Dorman, D. C., Chiu, W., Hales, B. F., Hauser, R., Johnson, K. J., Mantus, E., … Waters, K. M. (2018, May 19). Journal of Toxicology and Environmental Health Part B.

Toxicity associated with ingestion of a polyacrylic acid hydrogel dog pad

Dorman, D. C., Foster, M. L., Olesnevich, B., Bolon, B., Castel, A., Sokolsky-Papkov, M., & Mariani, C. L. (2018, June 11). Journal of Veterinary Diagnostic Investigation, Vol. 30, pp. 708–714.

Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing

Toxicology in Vitro, 41, 245–259.

Canine scent detection of canine cancer: a feasibility study

Veterinary Medicine: Research and Reports, Volume 8, 69–76.

Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease-associated pain

Veterinary Record, 180(19), 473–473.

Effect of wearing a Telemetry jacket on behavioral and physiologic parameters of dogs in the open-field test

Journal of the American Association for Laboratory Animal Science, 56(4), 382–389.

Fifty years of contributions by the American Board of Veterinary Toxicology

Dorman, D. C., Beasley, V. R., & McClellan, R. O. (2017, July 13). Journal of the American Veterinary Medical Association.

Interactions of manganese with iron, zinc, and copper in neonatal C57BL/6J and parkin mice following developmental oral manganese exposure

Data in Brief, 15, 908–915.

Manganese Neurodegeneration

Dorman, D. C. (2017, January 1). Advances in Neurotoxicology.

Metal imaging in the brain

Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics, 349–362.

Neonatal C57BL/6J and parkin mice respond differently following developmental manganese exposure: Result of a high dose pilot study

Foster, M. L., Bartnikas, T. B., Maresca-Fichter, H. C., Mercadante, C., Dash, M., Miller, C., & Dorman, D. C. (2017, October 12). NeuroToxicology.

Olfactory toxicity in rats following manganese chloride nasal instillation: A pilot study

Foster, M. L., Rao, D. B., Francher, T., Traver, S., & Dorman, D. C. (2017, September 14). NeuroToxicology.

Response to Editor: Regarding Foster et al., Neonatal C57BL/6J and parkin mice respond differently following developmental manganese exposure: Result of a high dose pilot study

Dorman, D. C. (2017, November 21). NeuroToxicology.

Survey of Diplomates of the American Board of Veterinary Toxicology Regarding Perceptions of the Value of This Certification

Dorman, D. C., & Kedrowicz, A. A. (2017, August 17). International Journal of Toxicology, Vol. 36, pp. 380–385.

Teaching Tip: Improving Students' Email Communication through an Integrated Writing Assignment in a Third-Year Toxicology Course

Journal of Veterinary Medical Education, 44(2), 280–289.

Best practice recommendations for prehospital veterinary care of dogs and cats

Journal of Veterinary Emergency and Critical Care, 26(2), 166–233.

Diphenhydramine exposure in dogs: 621 cases (2008–2013)

Worth, A. C., Wismer, T. A., & Dorman, D. C. (2016, June 16). Journal of the American Veterinary Medical Association.

Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure

Data in Brief, 6, 989–997.

Severity scoring of manganese health effects for categorical regression

Mattison, D. R., Milton, B., Krewski, D., Levy, L., Dorman, D. C., Aggett, P. J., … McGough, D. (2016, September 14). NeuroToxicology.

The effect of high dose oral manganese exposure on copper, iron and zinc levels in rats

Mercadante, C. J., Herrera, C., Pettiglio, M. A., Foster, M. L., Johnson, L. C., Dorman, D. C., & Bartnikas, T. B. (2016, March 17). BioMetals.

Thromboelastographic monitoring of the effect of unfractionated heparin in healthy dogs

McLaughlin, C. M., Marks, S. L., Dorman, D. C., Motsinger‐Reif, A., & Hanel, R. M. (2016, October 12). Journal of Veterinary Emergency and Critical Care.

A test for the evaluation of emotional reactivity in Labrador retrievers used for explosives detection

Sherman, B. L., Gruen, M. E., Case, B. C., Foster, M. L., Fish, R. E., Lazarowski, L., … Dorman, D. C. (2015, January 7). Journal of Veterinary Behavior, Vol. 10, pp. 94–102.

Answering the Call for Improved Chemical Alternatives Assessments (CAA)

Tickner, J. A., Dorman, D. C., & Shelton-Davenport, M. (2015, January 27). Environmental Science & Technology.

Extrapyramidal system neurotoxicity

In Handbook of Clinical Neurology (pp. 207–223).

Feasibility of flotation concentration of fungal spores as a method to identify toxigenic mushrooms

Veterinary Medicine: Research and Reports, 6, 1–9.

Olfactory discrimination and generalization of ammonium nitrate and structurally related odorants in Labrador retrievers

Animal Cognition, 18(6), 1255–1265.

Olfactory transport of manganese: Implications for neurotoxicity

Manganese in Health and Disease, 22, 119–132.

Pharmacokinetic Evaluation of the Equivalency of Gavage, Dietary, and Drinking Water Exposure to Manganese in F344 Rats

Foster, M. L., Bartnikas, T. B., Johnson, L. C., Herrera, C., Pettiglio, M. A., Keene, A. M., … Dorman, D. C. (2015, February 26). Toxicological Sciences.

The use of an open-field model to assess sound-induced fear and anxiety-associated behaviors in Labrador retrievers

Gruen, M. E., Case, B. C., Foster, M. L., Lazarowski, L., Fish, R. E., Landsberg, G., … Sherman, B. L. (2015, May 3). Journal of Veterinary Behavior, Vol. 10, pp. 338–345.

A comparison of pet and purpose-bred research dog (Canis familiaris) performance on human-guided object-choice tasks

Lazarowski, L., & Dorman, D. C. (2014, September 20). Behavioural Processes.

Evaluation of a point-of-care anticoagulant rodenticide test for dogs

Journal of Veterinary Emergency and Critical Care, 24(2), 168–173.

Acquisition of a visual discrimination and reversal learning task by Labrador retrievers

Lazarowski, L., Foster, M. L., Gruen, M. E., Sherman, B. L., Case, B. C., Fish, R. E., … Dorman, D. C. (2013, November 25). Animal Cognition, Vol. 17, pp. 787–792.

Assessment of geographical variation in the respiratory toxicity of desert dust particles

Taylor, K., Foster, M. L., Law, J. M. H., Centeno, J. A., Fornero, E., Henderson, M. S., … Dorman, D. C. (2013, June 1). Inhalation Toxicology.

Explosives detection by military working dogs: Olfactory generalization from components to mixtures

Lazarowski, L., & Dorman, D. C. (2013, December 1). Applied Animal Behaviour Science.

Inhalation dosimetry of hexamethylene diisocyanate vapor in the rat and human respiratory tracts

Schroeter, J. D., Kimbell, J. S., Asgharian, B., Tewksbury, E. W., Sochaski, M., Foster, M. L., … Andersen, M. E. (2013, February 1). Inhalation Toxicology.

Subject Matter Expert and Public Evaluations of a Veterinary Toxicology Course Brochure-Writing Assignment

Dorman, D. C., Alpi, K. M., & Chappell, K. H. (2013, January 8). Journal of Veterinary Medical Education.

Application of a Multi-Route Physiologically Based Pharmacokinetic Model for Manganese to Evaluate Dose-Dependent Neurological Effects in Monkeys

Schroeter, J. D., Dorman, D. C., Yoon, M., Nong, A., Taylor, M. D., Andersen, M. E., & Clewell, H. J. (2012, June 21). Toxicological Sciences.

Biological responses in rats exposed to cigarette smoke and Middle East sand (dust)

Dorman, D. C., Mokashi, V., Wagner, D. J., Olabisi, A. O., Wong, B. A., Moss, O. R., … Chapman, G. D. (2012, January 1). Inhalation Toxicology.

Neurological impacts from inhalation of pollutants and the nose-brain connection

NeuroToxicology, 33(4), 838–841.

The outdoor air pollution and brain health workshop

NeuroToxicology, 33(5), 972–984.

The outdoor air pollution and brain health workshop

[Review of]. NeuroToxicology, 33(5), 972–984.

Neurological impacts from inhalation of pollutants and the nose–brain connection

NeuroToxicology, 33(4), 838–841.

Physiologically Based Pharmacokinetic Modeling of Fetal and Neonatal Manganese Exposure in Humans: Describing Manganese Homeostasis during Development

Yoon, M., Schroeter, J. D., Nong, A., Taylor, M. D., Dorman, D. C., Andersen, M. E., & Clewell, H. J. (2011, May 27). Toxicological Sciences.

Analysis of Manganese Tracer Kinetics and Target Tissue Dosimetry in Monkeys and Humans with Multi-Route Physiologically Based Pharmacokinetic Models

Schroeter, J. D., Nong, A., Yoon, M., Taylor, M. D., Dorman, D. C., Andersen, M. E., & Clewell, H. J. (2010, December 27). Toxicological Sciences.

Multi-Dose-Route, Multi-Species Pharmacokinetic Models for Manganese and Their Use in Risk Assessment

Andersen, M. E., Dorman, D. C., Clewell, H. J., Taylor, M. D., & Nong, A. (2010, January 14). Journal of Toxicology and Environmental Health.

Acute sodium tungstate inhalation is associated with minimal olfactory transport of tungsten (188W) to the rat brain

Radcliffe, P. M., Olabisi, A. O., Wagner, D. J., Leavens, T., Wong, B. A., Struve, M. F., … Dorman, D. C. (2009, February 14). NeuroToxicology, Vol. 30, pp. 445–450.

Evaluating Placental Transfer and Tissue Concentrations of Manganese in the Pregnant Rat and Fetuses after Inhalation Exposures with a PBPK Model

Yoon, M., Nong, A., Clewell, H. J., Taylor, M. D., Dorman, D. C., & Andersen, M. E. (2009, September 2). Toxicological Sciences.

Lactational Transfer of Manganese in Rats: Predicting Manganese Tissue Concentration in the Dam and Pups from Inhalation Exposure with a Pharmacokinetic Model

Yoon, M., Nong, A., Clewell, H. J., Taylor, M. D., Dorman, D. C., & Andersen, M. E. (2009, September 2). Toxicological Sciences.

Pharmacokinetics of radiolabeled tungsten (¹⁸⁸W) in male Sprague-Dawley rats following acute sodium tungstate inhalation

Radcliffe, P. M., Leavens, T. L., Wagner, D. J., Olabisi, A. O., Struve, M. F., Wong, B. A., … Dorman, D. C. (2009, December 17). Inhalation Toxicology, Vol. 22, pp. 69–76.

Provisional Advisory Levels (PALs) for acrylonitrile

Goldhaber, S., Dorman, D., Gardner, D., & Adeshina, F. (2009, October 14). Inhalation Toxicology.

Provisional Advisory Levels (PALs) for hydrogen sulfide (H₂S)

Marshall, T., Dorman, D., Gardner, D., & Adeshina, F. (2009, October 14). Inhalation Toxicology.

Reproductive toxicity and pharmacokinetics of di‐n‐butyl phthalate (DBP) following dietary exposure of pregnant rats

Struve, M. F., Gaido, K. W., Hensley, J. B., Lehmann, K. P., Ross, S. M., Sochaski, M. A., … Dorman, D. C. (2009, July 7). Birth Defects Research Part B Developmental and Reproductive Toxicology.

Application of Physiological Computational Fluid Dynamics Models to Predict Interspecies Nasal Dosimetry of Inhaled Acrolein

Inhalation Toxicology, 20(3), 227–243.

Derivation of an Inhalation Reference Concentration Based upon Olfactory Neuronal Loss in Male Rats following Subchronic Acetaldehyde Inhalation

Dorman, D. C., Struve, M. F., Wong, B. A., Gross, E. A., Parkinson, C., Willson, G. A., … Andersen, M. E. (2008, January 1). Inhalation Toxicology.

Duration of airborne-manganese exposure in rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity

NeuroToxicology, 29(3), 377–385.

Gene Expression Changes Following Acute Hydrogen Sulfide (H₂S)-induced Nasal Respiratory Epithelial Injury

Roberts, E. S., Thomas, R. S., & Dorman, D. C. (2008, May 8). Toxicologic Pathology.

Genotoxicity of intermittent co-exposure to benzene and toluene in male CD-1 mice

Wetmore, B. A., Struve, M. F., Gao, P., Sharma, S., Allison, N., Roberts, K. C., … Dorman, D. C. (2008, March 29). Chemico-Biological Interactions.

Manganese Tissue Dosimetry in Rats and Monkeys: Accounting for Dietary and Inhaled Mn with Physiologically based Pharmacokinetic Modeling

Nong, A., Taylor, M. D., Clewell, H. J., Dorman, D. C., & Andersen, M. E. (2008, December 19). Toxicological Sciences.

Metabolomic Analyses of Body Fluids after Subchronic Manganese Inhalation in Rhesus Monkeys

Dorman, D. C., Struve, M. F., Norris, A., & Higgins, A. J. (2008, August 6). Toxicological Sciences.

Nasal Uptake of Inhaled Acrolein in Rats

Struve, M. F., Wong, V. A., Marshall, M. W., Kimbell, J. S., Schroeter, J. D., & Dorman, D. C. (2008, January 1). Inhalation Toxicology.

Pharmacokinetic Modeling of Manganese in the Rat IV: Assessing Factors that Contribute to Brain Accumulation During Inhalation Exposure

Journal of Toxicology and Environmental Health, Part A, 71(7), 413–426.

Respiratory Tract Responses in Male Rats Following Subchronic Acrolein Inhalation

Dorman, D. C., Struve, M. F., Wong, B. A., Marshall, M. W., Gross, E. A., & Willson, G. A. (2008, January 1). Inhalation Toxicology.

“Current Pathology Techniques” Symposium Review: Advances and Issues in Neuropathology

Bolon, B., Anthony, D. C., Butt, M., Dorman, D., Green, M. V., Little, P. B., … Sills, R. C. (2008, July 22). Toxicologic Pathology.