Dalton Hilovsky

College of Agriculture and Life Sciences

Works (2)

Updated: April 8th, 2024 08:24

2024 article

Variation in Biosynthesis and Metal-Binding Properties of Isonitrile-Containing Peptides Produced by Mycobacteria versus Streptomyces

Chen, T.-Y., Chen, J., Ruszczycky, M. W., Hilovsky, D., Hostetler, T., Liu, X., … Chang, W.-chen. (2024, March 19). ACS CATALYSIS, Vol. 3.

By: T. Chen n, J. Chen *, M. Ruszczycky*, D. Hilovsky n, T. Hostetler n, X. Liu n, J. Zhou *, W. Chang n 

author keywords: isonitriles; Fe/2OG enzymes; metallophores; Mycobacterium; natural products
Sources: Web Of Science, NC State University Libraries
Added: April 1, 2024

2023 journal article

Excision of a Protein-Derived Amine for <i>p</i>-Aminobenzoate Assembly by the Self-Sacrificial Heterobimetallic Protein CADD

BIOCHEMISTRY, 62(22), 3276–3282.

By: H. Phan n, O. Manley n, S. Skirboll n, L. Cha n , D. Hilovsky n, W. Chang n , P. Thompson n , X. Liu n, T. Makris n 

TL;DR: Turnover studies using limiting O2 have identified a para-aminobenzaldehyde metabolic intermediate that is formed on the path to pABA formation and use of pABCHO and other probe substrates shows that the heterobimetallic Fe/Mn form of the enzyme is capable of oxygen insertion to generate the pA BA-carboxylate. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 12, 2023

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