David Joseph Kleisch

Works (1)

Updated: July 5th, 2023 14:34

2020 journal article

Atenolol in cats with subclinical hypertrophic cardiomyopathy: a double-blind, placebo-controlled, randomized clinical trial of effect on quality of life, activity, and cardiac biomarkers

JOURNAL OF VETERINARY CARDIOLOGY, 30, 77–91.

By: A. Coleman  n, T. DeFrancesco n , E. Griffiths n, B. Lascelles  n, D. Kleisch n, C. Atkins n, B. Keene n

author keywords: Feline; Beta-btocker; Accelerometry
MeSH headings : Administration, Oral; Animals; Anti-Arrhythmia Agents / administration & dosage; Anti-Arrhythmia Agents / therapeutic use; Atenolol / administration & dosage; Atenolol / therapeutic use; Biomarkers / blood; Cardiomyopathy, Hypertrophic / drug therapy; Cardiomyopathy, Hypertrophic / veterinary; Cat Diseases / blood; Cat Diseases / drug therapy; Cats; Double-Blind Method; Female; Male; Quality of Life; Treatment Outcome
TL;DR: This study failed to identify an effect of subclinical HCM on owner-assessed QOL or activity or a treatment effect of atenolol on these variables at the dosage evaluated, and these findings do not support a treatment benefit of atanolol for the goal of symptom reduction in cats with sub clinical HCM. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 21, 2020

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