Dylan Wallis

Works (6)

Updated: November 8th, 2023 05:00

2023 journal article

Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57(41), 15348–15355.

By: D. Wallis n, N. Kotlarz n , D. Knappe n , D. Collier *, C. Lea *, D. Reif n , J. McCord *, M. Strynar *, J. DeWitt*, J. Hoppin n 

author keywords: exposure; PFAS; water; humans; environment; toxicokinetic modeling
TL;DR: These fluoroethers had biological half-Lives longer than published half-lives for PFHxA and PFHpA but shorter than those for PFOA andPFOS (800-1200 days). (via Semantic Scholar)
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6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 7, 2023

2022 journal article

Source apportionment of serum PFASs in two highly exposed communities

SCIENCE OF THE TOTAL ENVIRONMENT, 855.

By: D. Wallis n, K. Barton *, D. Knappe n , N. Kotlarz n , C. McDonough *, C. Higgins *, J. Hoppin n , J. Adgate *

author keywords: Source apportionment; Receptor models; PFAS; Per fluoroalkyl substances
MeSH headings : Humans; Fluorocarbons / analysis; Nutrition Surveys; Drinking Water / analysis; Multivariate Analysis; Principal Component Analysis; Alkanesulfonic Acids / analysis; Water Pollutants, Chemical / analysis
TL;DR: Effectiveness of three source apportionment methods for identifying contributors to human serum PFAS concentrations in two highly exposed populations in Colorado and North Carolina where drinking water was contaminated via upstream sources is assessed. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 11, 2022

2022 journal article

Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish

JOURNAL OF HAZARDOUS MATERIALS, 431.

By: L. Truong *, Y. Rericha *, P. Thunga n , S. Marvel n, D. Wallis n, M. Simonich *, J. Field *, D. Cao *, D. Reif n , R. Tanguay  n

author keywords: PFAS; Developmental toxicity; Structure-activity relationship; Abnormal behavior; Zebrafish
MeSH headings : Animals; Fluorocarbons / analysis; Larva; Teratogens; Zebrafish
TL;DR: The results illustrate the power of a multi-dimensional in vivo platform to assess the developmental (neuro)toxicity of diverse PFAS and in the acceleration of PFAS safety research. (via Semantic Scholar)
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6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 8, 2022

2021 review

Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions

[Review of ]. TOXICS, 9(4).

By: D. Wallis n, L. Truong *, J. La Du*, R. Tanguay * & D. Reif n 

author keywords: endocrine-disrupting chemical (EDC); gene-environment interaction (GxE); differential susceptibility
TL;DR: It is proposed that EDCs causing such differential responses may be identified by looking for a signal of population variability after exposure, and called for further, deeper analysis of the EDCs, particularly the thyroid disruptors, to identify if these chemicals participate in GxE leading to differences in susceptibility. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 7, 2021

2019 journal article

Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

ARCHIVES OF TOXICOLOGY, 94(2), 469–484.

By: M. Kosnik n, J. Strickland *, S. Marvel n, D. Wallis n, K. Wallace *, A. Richard *, D. Reif n , T. Shafer *

author keywords: Neurotoxicity; Screening; ToxCast
MeSH headings : Animals; Cell Culture Techniques / instrumentation; Cell Culture Techniques / methods; Databases, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical / methods; Machine Learning; Microelectrodes; Nerve Net / drug effects; Neural Networks, Computer; Neurons / drug effects; Neurotoxicity Syndromes / pathology; Rats, Long-Evans; Toxicity Tests / methods
TL;DR: It is demonstrated that multivariate MEA activity patterns can efficiently screen for diverse chemical activities relevant to neurotoxicity, and that response patterns may have predictive value related to chemical structural features. (via Semantic Scholar)
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15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 30, 2020

2019 journal article

Knockdown of arylalkylamine N-acetyltransferase-like 2 in Drosophila melanogaster

ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY, 102(4).

By: R. Anderson *, D. Wallis*, A. Aguirre*, D. Holliday * & D. Merkler *

author keywords: arylalkylamine N-acetyltransferase; Drosophila melanogaster; expression knockdown; fatty acid amide; LC-QToF-MS; N-palmitoyldopamine; UAS; Gal4
MeSH headings : Acyltransferases / genetics; Acyltransferases / metabolism; Animals; Dopamine / analogs & derivatives; Dopamine / biosynthesis; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / enzymology; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Gene Silencing
TL;DR: Reduced expression of AANATL2 decreased the cellular levels of N-palmitoyldopamine (PALDA), providing strong evidence that AANatL2 is responsible for the biosynthesis of PALDA in vivo. (via Semantic Scholar)
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Source: Web Of Science
Added: August 26, 2019

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