Daniel Comins Comins, D. L. (2022). Synthesis of MAPA Reagents and 2-Alkyl(aryl)aminopyridines from 2-Bromopyridine Using the Goldberg Reaction. MOLECULES, 27(6). https://doi.org/10.3390/molecules27061833 Bori, I. D., & Comins, D. L. (2021). Preparation of substituted alkoxypyridines via directed metalation and metal-halogen exchange. ARKIVOC, 57–72. https://doi.org/10.24820/ark.5550190.p011.464 Comins, D., & Ma, D. (2016, November 4). Editorial for the Special Issue on Heterocycles. JOURNAL OF ORGANIC CHEMISTRY, Vol. 81, pp. 10107–10108. https://doi.org/10.1021/acs.joc.6b02488 Tsukanov, S. V., Marks, L. R., & Comins, D. L. (2016). Studies toward the Synthesis of Lepadiformine A. JOURNAL OF ORGANIC CHEMISTRY, 81(21), 10433–10443. https://doi.org/10.1021/acs.joc.6b01514 Zhu, J., Enamorado, M. F., & Comins, D. L. (2016). Synthesis of C-4 Substituted Amido Nicotine Derivatives via Copper(I)- and (II)-Catalyzed Cross-Coupling Reactions. JOURNAL OF ORGANIC CHEMISTRY, 81(22), 11529–11534. https://doi.org/10.1021/acs.joc.6b02319 Enamorado, M. F., Connelly, C. M., Deiters, A., & Comins, D. L. (2015). A concise synthesis of the Lycopodium alkaloid cermizine D. TETRAHEDRON LETTERS, 56(23), 3683–3685. https://doi.org/10.1016/j.tetlet.2015.04.013 Hiebel, A.-C., & Comins, D. L. (2015). Novel approach toward the morphine skeleton. Synthesis of 1-(5-benzyloxy-2-bromo-4-methoxybenzyl)-6-oxo-3,4,6,7,8,8a-hexahydro-1H-isoquinoline-2-carboxylic acid phenyl ester via N-acylpyridinium salt chemistry. TETRAHEDRON, 71(39), 7354–7360. https://doi.org/10.1016/j.tet.2015.04.086 Neufeldt, S. R., Jimenez-Oses, G., Comins, D. L., & Houk, K. N. (2014). A Twist on Facial Selectivity of Hydride Reductions of Cyclic Ketones: Twist-Boat Conformers in Cyclohexanone, Piperidone, and Tropinone Reactions. JOURNAL OF ORGANIC CHEMISTRY, 79(23), 11609–11618. https://doi.org/10.1021/jo5022635 Cash, B. M., Prevost, N., Wagner, F. F., & Comins, D. L. (2014). Studies toward the Total Synthesis of Dihydrolycolucine. Preparation of AB and CEF Ring Fragments. JOURNAL OF ORGANIC CHEMISTRY, 79(12), 5740–5745. https://doi.org/10.1021/jo500878v Tsukanov, S. V., & Comins, D. L. (2014). Total Synthesis of Alkaloid 205B. JOURNAL OF ORGANIC CHEMISTRY, 79(19), 9074–9085. https://doi.org/10.1021/jo501415r Comins, D. L., Higuchi, K., & Young, D. W. (2013). [Review of Dihydropyridine preparation and application in the synthesis of pyridine derivatives]. Advances in heterocyclic chemistry, vol 110, 110, 175–235. Sahn, J. J., Bharathi, P., & Comins, D. L. (2012). Studies toward the synthesis of spirolucidine. Preparation of ABC and EF ring fragments. TETRAHEDRON LETTERS, 53(11), 1347–1350. https://doi.org/10.1016/j.tetlet.2011.12.127 Tsukanov, S. V., & Comins, D. L. (2011). Concise Total Synthesis of the Frog Alkaloid (-)-205B. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 50(37), 8626–8628. https://doi.org/10.1002/anie.201103596 Walker, S. H., Lilley, L. M., Enamorado, M. F., Comins, D. L., & Muddiman, D. C. (2011). Hydrophobic Derivatization of N-linked Glycans for Increased Ion Abundance in Electrospray Ionization Mass Spectrometry. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22(8), 1309–1317. https://doi.org/10.1007/s13361-011-0140-x Watson, V. G., Motsinger-Reif, A., Hardison, N. E., Peters, E. J., Havener, T. M., Everitt, L., … McLeod, H. L. (2011). Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees. PLoS One, 6(5). Enamorado, M. F., Ondachi, P. W., & Comins, D. L. (2010). A Five-Step Synthesis of (S)-Macrostomine from (S)-Nicotine. ORGANIC LETTERS, 12(20), 4513–4515. https://doi.org/10.1021/ol101887b Wolfe, B. H., Libby, A. H., Al-awar, R. S., Foti, C. J., & Comins, D. L. (2010). Asymmetric Synthesis of All the Known Phlegmarine Alkaloids. JOURNAL OF ORGANIC CHEMISTRY, 75(24), 8564–8570. https://doi.org/10.1021/jo1019688 Walker, S. H., Papas, B. N., Comins, D. L., & Muddiman, D. C. (2010, August 1). Interplay of Permanent Charge and Hydrophobicity in the Electrospray Ionization of Glycans. ANALYTICAL CHEMISTRY, Vol. 82, pp. 6636–6642. https://doi.org/10.1021/ac101227a King, L. S., Smith, E., & Comins, D. L. (2010). Regiospecific synthesis of nicotine derivatives. Ondachi, P. W., & Comins, D. L. (2010). Synthesis of Fused-Ring Nicotine Derivatives from (S)-Nicotine. JOURNAL OF ORGANIC CHEMISTRY, 75(5), 1706–1716. https://doi.org/10.1021/jo9026929 Sahn, J. J., & Comins, D. L. (2010). [2+2] Photochemical Cycloaddition/Ring Opening of 6-Alkenyl-2,3-dihydro-4-pyridones. JOURNAL OF ORGANIC CHEMISTRY, 75(19), 6728–6731. https://doi.org/10.1021/jo101276q Capracotta, S. S., & Comins, D. L. (2009). Chiral amino alcohols derived from (S)-6-chloronicotine as catalysts for asymmetric synthesis. TETRAHEDRON LETTERS, 50(16), 1806–1808. https://doi.org/10.1016/j.tetlet.2009.02.012 Williams, D. K., Jr., Comins, D. L., Whitten, J. L., & Muddiman, D. C. (2009). Evaluation of the ALiPHAT Method for PC-IDMS and Correlation of Limits-of-Detection with Nonpolar Surface Area. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 20(11), 2006–2012. https://doi.org/10.1016/j.jasms.2009.07.019 Shuford, C. M., Comins, D. L., Whitten, J. L., Burnett, J. C., Jr., & Muddiman, D. C. (2010). Improving limits of detection for B-type natriuretic peptide using PC-IDMS: An application of the ALiPHAT strategy. ANALYST, 135(1), 36–41. https://doi.org/10.1039/b919484c Bereman, M. S., Comins, D. L., & Muddiman, D. C. (2010). Increasing the hydrophobicity and electrospray response of glycans through derivatization with novel cationic hydrazides. CHEMICAL COMMUNICATIONS, 46(2), 237–239. https://doi.org/10.1039/b915589a McCall, W. S., & Comins, D. L. (2009). Synthesis of 1,3-Amino Alcohol Derivatives via a Silicon-Mediated Ring-Opening of Substituted Piperidines. ORGANIC LETTERS, 11(13), 2940–2942. https://doi.org/10.1021/ol9010757 Comins, D. L., & Smith, E. D. (2009). Synthesis of nicotine derivatives from nicotine. Eliyahu, D., Nojima, S., Capracotta, S. S., Comins, D. L., & Schal, C. (2008). Identification of cuticular lipids eliciting interspecific courtship in the German cockroach, Blattella germanica. NATURWISSENSCHAFTEN, 95(5), 403–412. https://doi.org/10.1007/s00114-007-0339-7 McCall, W. S., Grillo, T. A., & Comins, D. L. (2008). N-Acyldihydropyridones as Synthetic Intermediates. A Stereoselective Synthesis of Acyclic Amino Alcohols Containing Multiple Chiral Centers. JOURNAL OF ORGANIC CHEMISTRY, 73(24), 9744–9751. https://doi.org/10.1021/jo802029y McCall, W. S., Grillo, T. A., & Comins, D. L. (2008). Stereoselective synthesis of acyclic amino alcohols via von Braun ring opening of chiral piperidines. ORGANIC LETTERS, 10(15), 3255–3257. https://doi.org/10.1021/ol801123x Comins, D. L., & D., S. E. (2008). Synthesis of nicotine derivatives from nicotine. Washington, DC: U.S. Patent and Trademark Office. Williams, D. K., Meadows, C. W., Bori, I. D., Hawkridge, A. M., Comins, D. L., & Muddiman, D. (2008). Synthesis, characterization, and application of lodoacetamide derivatives utilized for the ALiPHAT strategy. Journal of the American Chemical Society, 130(7), 2122-. https://doi.org/10.1021/jao076849y Frahm, J. L., Bori, I. D., Comins, D. L., Hawkridge, A. M., & Muddiman, D. C. (2007). Achieving augmented limits of detection for peptides with hydrophobic alkyl tags. ANALYTICAL CHEMISTRY, 79(11), 3989–3995. https://doi.org/10.1021/ac070558q Bharathi, P., & Comins, D. L. (2008). Asymmetric synthesis of C-2-symmetric vicinal diamines via reductive dimerization of N-acylpyridinium and related salts. ORGANIC LETTERS, 10(2), 221–223. https://doi.org/10.1021/ol702595d Comins, D. L., Dinsmore, J. M., & Marks, L. R. (2007). One-pot terminal alkene homologation using a tandem olefin cross-metathesis/allylic carbonate reduction sequence. CHEMICAL COMMUNICATIONS, (40), 4170–4171. https://doi.org/10.1039/b709754a Wagner, F. F., & Comins, D. L. (2007). Recent advances in the synthesis of nicotine and its derivatives. TETRAHEDRON, 63(34), 8065–8082. https://doi.org/10.1016/j.tet.2007.04.100 Comins, D. L., Fevrier, F., & Smith, E. D. (2007). Regioselective halogenation of nicotine and substituted nicotines. Washington, DC: U.S. Patent and Trademark Office. King, L. S., Smith, E., & Comins, D. L. (2007). Regiospecific synthesis of nicotine derivatives. Washington, DC: U.S. Patent and Trademark Office. Ondachi, P. W., & Comins, D. L. (2008). Synthesis and regioselective substitution of C-6 alkoxy derivatives of (S)-nicotine. TETRAHEDRON LETTERS, 49(3), 569–572. https://doi.org/10.1016/j.tetlet.2007.11.041 Comins, D. L., & Higuchi, K. (2007). Synthesis of the benzo-fused indolizidine alkaloid mimics. Beilstein Journal of Organic Chemistry, 3. Comins, D. L., & Smith, E. D. (2006). A six-step synthesis of (S)-5-ethenyl-3-(1-methy1-2-pyrrolidinyl)pyridine (SIB-1508Y) from (S)-nicotine. TETRAHEDRON LETTERS, 47(9), 1449–1451. https://doi.org/10.1016/j.tetlet.2005.12.085 Wagner, F. F., & Comins, D. L. (2006). Expedient five-step synthesis of SIB-1508Y from natural nicotine. JOURNAL OF ORGANIC CHEMISTRY, 71(22), 8673–8675. https://doi.org/10.1021/jo0616052 Stumpf, C. F., Comins, D. L., Sparks, T. C., Donohue, K. V., & Roe, R. M. (2007). Insecticidal activity and mode of action of novel nicotinoids synthesized by new acylpyridinium salt chemistry and directed lithiation. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 87(3), 211–219. https://doi.org/10.1016/j.pestbp.2006.07.012 Wagner, F. F., & Comins, D. L. (2006). Regioselective 5-, 4-, and 2-substitution of (S)-6-chloronicotine and 4-substitution of (S)-5-chloronicotine. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2006(16), 3562–3565. https://doi.org/10.1002/ejoc.200600415 Comins, D. L., Fevrier, F., & Smith, E. D. (2006). Regioselective halogenation of nicotine and substituted nicotines. Washington, DC: U.S. Patent and Trademark Office. King, L. S., Smith, E., & Comins, D. L. (2006). Regiospecific synthesis of nicotine derivatives. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Huang, S. (2006). Short synthesis of pyridine-based pharmaceutical intermediates. Washington, DC: U.S. Patent and Trademark Office. Wagner, F. F., & Comins, D. L. (2006). Six-step synthesis of (S)-brevicolline from (S)-nicotine. ORGANIC LETTERS, 8(16), 3549–3552. https://doi.org/10.1021/ol061334h Comins, D. L., & Smith, E. D. (2006). Synthesis of nicotine derivatives from nicotine. Washington, DC: U.S. Patent and Trademark Office. Gotchev, D. B., & Comins, D. L. (2006). Synthetic studies toward (-)-FR901483 using a conjugate allylation to install the C-1 quaternary carbon. JOURNAL OF ORGANIC CHEMISTRY, 71(25), 9393–9402. https://doi.org/10.1021/jo061677t Comins, D. L., & Sahn, J. J. (2005). A six-step asymmetric synthesis of (+)-hyperaspine. ORGANIC LETTERS, 7(23), 5227–5228. https://doi.org/10.1021/ol052068v Comins, D. L., & Hiebel, A. U. (2005). Asymmetric synthesis of 3,3-disubstituted isoindolinones. TETRAHEDRON LETTERS, 46(34), 5639–5642. https://doi.org/10.1016/j.tetlet.2005.06.105 Comins, D. L., Kuethe, J. T., Miller, T. M., Fevrier, F. C., & Brooks, C. A. (2005). Diels-alder reactions of N-acyl-2-alkyl(aryl)-5-vinyl-2,3-dihydro-4-pyridones. JOURNAL OF ORGANIC CHEMISTRY, 70(13), 5221–5234. https://doi.org/10.1021/jo050559n Fevrier, F. C., Smith, E. D., & Comins, D. L. (2005). Regioselective C-2 and C-6 substitution of (S)-nicotine and nicotine derivatives. ORGANIC LETTERS, 7(24), 5457–5460. https://doi.org/10.1021/ol052196j Comins, D. L., Nolan, J. M., & Bori, I. D. (2005). Regioselective lithium-halogen exchange and palladium-catalyzed cross-coupling reactions of 2,4-dihaloquinolines. TETRAHEDRON LETTERS, 46(39), 6697–6699. https://doi.org/10.1016/j.tetlet.2005.07.137 Comins, D. L., & Huang, S.-L. (2005). Short synthesis of pyridine-based pharmaceutical intermediates. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., King, L. S., Smith, E. D., & Fevrier, F. C. (2005). Synthesis of C-4 substituted nicotine derivatives via an N-acylpyridinium salt of (S)-nicotine. ORGANIC LETTERS, 7(22), 5059–5062. https://doi.org/10.1021/ol0520469 Smith, E. D., Fevrier, F. C., & Comins, D. L. (2006). Synthesis of nicotine derivatives via reductive disilylation of (S)-nicotine. ORGANIC LETTERS, 8(2), 179–182. https://doi.org/10.1021/ol052099q Young, D. W., & Comins, D. L. (2005). Tandem directed lithiations of N-boc-1,2-dihydropyridines toward highly functionalized 2,3-dihydro-4-pyridones. ORGANIC LETTERS, 7(25), 5661–5664. https://doi.org/10.1021/ol052313a Kuethe, J. T., & Comins, D. L. (2004). Addition of indolyl and pyrrolyl grignard reagents to 1-acylpyridinium salts. JOURNAL OF ORGANIC CHEMISTRY, 69(8), 2863–2866. https://doi.org/10.1021/jo049943v Comins, D. L., Schilling, S., & Zhang, Y. C. (2005). Asymmetric synthesis of 3-substituted isoindolinones: Application to the total synthesis of (+)-lennoxamine. ORGANIC LETTERS, 7(1), 95–98. https://doi.org/10.1021/ol047824w Kuethe, J. T., & Comins, D. L. (2004). Asymmetric total synthesis of (+)-cannabisativine. JOURNAL OF ORGANIC CHEMISTRY, 69(16), 5219–5231. https://doi.org/10.1021/jo049724+ Gotchev, D. B., & Comins, D. L. (2004). Novel heterocyclic systems. Synthesis of 2,7-dimethyl-10-oxa-1,8-diaza-anthracen-9-one and derivatives. TETRAHEDRON, 60(51), 11751–11758. https://doi.org/10.1016/j.tet.2004.09.111 Fang, F. G., Huie, E. M., Xie, S., & Comins, D. L. (2004). Preparation of a camptothecin derivative by intramolecular cyclisation. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Huang, S.-L. (2004). Short synthesis of pyridine-based pharmaceutical intermediates. Washington, DC: U.S. Patent and Trademark Office. Kuethe, J. T., Brooks, C. A., & Comins, D. L. (2003). Diels-Alder reactions of 5-vinyl-1-acyl-2-aryl-2,3-dihydro-4-pyridones: regio- and stereoselective synthesis of octahydroquinolines. ORGANIC LETTERS, 5(3), 321–323. https://doi.org/10.1021/ol027308a Fang, F. G., Huie, E. M., Xie, S.-P., & Comins, D. L. (2003). Preparation of a camptothecin derivative by intramolecular cyclisation. Washington, DC: U.S. Patent and Trademark Office. Nolan, J. M., & Comins, D. L. (2003). Regioselective sonogashira couplings of 2,4-dibromoquinolines. A correction. JOURNAL OF ORGANIC CHEMISTRY, 68(9), 3736–3738. https://doi.org/10.1021/jo034122w Comins, D. L., & Huang, S.-L. (2003). Short synthesis of pyridine-based pharmaceutical intermediates. Washington, DC: U.S. Patent and Trademark Office. Kuethe, J. T., & Comins, D. L. (2003). Tandem Diels-Alder cyclization/aromatization reactions of 5-vinyl-1-acyl-2-aryl-2,3-dihydro-4-pyridones. TETRAHEDRON LETTERS, 44(22), 4179–4182. https://doi.org/10.1016/S0040-4039(03)00930-4 Williams, A. L., Grillo, T. A., & Comins, D. L. (2002). A novel free-radical ring contraction of a cyclic carbamate. JOURNAL OF ORGANIC CHEMISTRY, 67(6), 1972–1973. https://doi.org/10.1021/jo0163290 Fang, F. G., Huie, E. M., Xie, S., & Comins, D. L. (2002). Preparation of a camptothecin derivative by intramolecular cyclisation. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., Killpack, M. O., Despagnet, E., & Zeller, E. (2002). Synthesis and reactions of enantiopure 1-acyl-2- [triaryl(alkyl)silyl]-2,3-dihydro-4-pyridones. Heterocycles, 58(2002 Nov 22), 505–519. Joseph, S., & Comins, D. L. (2002). Synthetic applications of chiral 2,3-dihydro-4-pyridones. Current Opinion in Drug Discovery & Development, 5(6), 870–880. Comins, D. L., Zheng, X. L., & Goehring, R. R. (2002). Total synthesis of the putative structure of the lupin alkaloid plumerinine. ORGANIC LETTERS, 4(9), 1611–1613. https://doi.org/10.1021/ol025820q Comins, D. L., & Nolan, J. M. (2001). A practical six-step synthesis of (S)-camptothecin. ORGANIC LETTERS, 3(26), 4255–4257. https://doi.org/10.1021/ol0169271 Comins, D. L., Sandelier, M. J., & Grillo, T. A. (2001). Asymmetric synthesis of (+)-deoxoprosopinine. Journal of Organic Chemistry, 66(20), 6829–6832. https://doi.org/10.1021/jo015834u Comins, D. L., Huang, S. L., McArdle, C. L., & Ingalls, C. L. (2001). Enantiopure 2,3-dihydro-4-pyridones as synthetic intermediates: A concise asymmetric synthesis of (+)-allopumiliotoxin 267A. ORGANIC LETTERS, 3(3), 469–471. https://doi.org/10.1021/ol0069709 Comins, D. L., & Fulp, A. B. (2001). Enantiopure 2,3-dihydro-4-pyridones as synthetic intermediates: asymmetric synthesis of 1-deoxynojirimycin. TETRAHEDRON LETTERS, 42(39), 6839–6841. https://doi.org/10.1016/S0040-4039(01)01432-0 Comins, D. L., & Ollinger, C. G. (2001). Inter- and intramolecular Horner-Wadsworth-Emmons reactions of 5-(diethoxyphosphoryl)-1-acyl-2-alkyl(aryl)-2,3-dihydro-4-pyridones. TETRAHEDRON LETTERS, 42(25), 4115–4118. https://doi.org/10.1016/S0040-4039(01)00690-6 Comins, D. L., & Williams, A. L. (2001). Model studies toward the total synthesis of the Lycopodium alkaloid spirolucidine. ORGANIC LETTERS, 3(20), 3217–3220. https://doi.org/10.1021/ol016556o Comins, D. L., Brooks, C. A., & Ingalls, C. L. (2001). Reduction of N-acyl-2,3-dihydro-4-pyridones to N-acyl-4-piperidones using zinc/acetic acid. JOURNAL OF ORGANIC CHEMISTRY, 66(6), 2181–2182. https://doi.org/10.1021/jo001609l Comins, D. L., Hiebel, A. C., & Huang, S. L. (2001). Synthesis and reactivity of N-acyl-5-(1-hydroxyalkyl)-2,3-dihydro-4-pyridones. ORGANIC LETTERS, 3(5), 769–771. https://doi.org/10.1021/ol015529v Kuethe, J. T., & Comins, D. L. (2000). Addition of metallo enolates to chiral 1-acylpyridinium salts: Total synthesis of (+)-cannabisativine. ORGANIC LETTERS, 2(6), 855–857. https://doi.org/10.1021/ol0056271 Brooks, C. A., & Comins, D. L. (2000). Asymmetric synthesis of (2S,4R)-4-hydroxypipecolic acid. TETRAHEDRON LETTERS, 41(19), 3551–3553. https://doi.org/10.1016/s0040-4039(00)00460-3 Comins, D. L., & Williams, A. L. (2000). Asymmetric synthesis of erythro- and threo-2-(1-hydroxyalkyl)piperidines via iodocyclocarbamation of 1-acyl-2-alkenyl-1,2,3,6-tetrahydropyridines. TETRAHEDRON LETTERS, 41(16), 2839–2842. https://doi.org/10.1016/S0040-4039(00)00298-7 Fang, F. G., Huie, E. M., Xie, S.-P., & Comins, D. L. (2000). Preparation of a camptothecin derivative by intramolecular cyclisation. Washington, DC: U.S. Patent and Trademark Office. Huang, S. L., & Comins, D. L. (2000). Total synthesis of (+)-streptazolin. CHEMICAL COMMUNICATIONS, (7), 569–570. https://doi.org/10.1039/b001425g Comins, D. L. (1999). Asymmetric synthesis and synthetic utility of 2,3-dihydro-4-pyridones. JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol. 36, pp. 1491–1500. https://doi.org/10.1002/jhet.5570360610 Comins, D. L., & Green, G. M. (1999). Asymmetric synthesis of dienomycin C. TETRAHEDRON LETTERS, 40(2), 217–218. https://doi.org/10.1016/S0040-4039(98)02273-4 Comins, D. L., Libby, A. H., Al-awar, R. S., & Foti, C. J. (1999, April 2). Asymmetric synthesis of the Lycopodium alkaloid, N-a-acetyl-N-b-methylphlegmarine. https://doi.org/10.1021/jo990192k Comins, D. L., Kuethe, J. T., Hong, H., Lakner, F. J., Concolino, T. E., & Rheingold, A. L. (1999). Diastereoselective addition of prochiral metallo enolates to chiral 1-acylpyridinium salts. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 121(11), 2651–2652. https://doi.org/10.1021/ja990024+ Comins, D. L., & Fulp, A. B. (1999). Enantiopure N-acyldihydropyridones as synthetic intermediates: Asymmetric synthesis of (-)-slaframine. ORGANIC LETTERS, 1(12), 1941–1943. https://doi.org/10.1021/ol991083v Comins, D. L., Zhang, Y. M., & Joseph, S. P. (1999). Enantiopure N-acyldihydropyridones as synthetic intermediates: Asymmetric synthesis of benzomorphans. ORGANIC LETTERS, 1(4), 657–659. https://doi.org/10.1021/ol990738p Comins, D. L., Brooks, C. A., Al-awar, R. S., & Goehring, R. R. (1999). IMDA/retro-Mannich approach to cis-perhydroquinoline Lycopodium alkaloids: Asymmetric synthesis of (+)-luciduline. ORGANIC LETTERS, 1(2), 229–231. https://doi.org/10.1021/ol990028j Kuethe, J. T., & Comins, D. L. (1999). The Mukaiyama-Michael reaction of N-acyl-2,3-dihydro-4- pyridones: Regio- and stereoselective synthesis of cis-2,6- disubstituted 1,2,5,6-tetrahydropyridines. Organic Letters, 1(7), 1031–1033. https://doi.org/10.1021/ol9908124 Comins, D. L., Stolze, D. A., Thakker, P., & McArdle, C. L. (1998). C-3 acetoxylation of N-acyl-2,3-dihydro-4-pyridones. TETRAHEDRON LETTERS, 39(32), 5693–5696. https://doi.org/10.1016/S0040-4039(98)01195-2 Comins, D. L., Lee, Y. S., & Boyle, P. D. (1998). Intramolecular photocycloaddition of a tethered bis-2,3-dihydro-4-pyridone: Stereochemistry and reactivity of the cycloadduct. TETRAHEDRON LETTERS, 39(3-4), 187–190. https://doi.org/10.1016/S0040-4039(97)10520-2 Comins, D. L., Foti, C. J., & Libby, A. H. (1998). Model studies toward the synthesis of N alpha-acetyl-N beta- methylphlegmarine: Addition of cyclohexylmethyl organometallics to 1-acylpyridinium salts. Heterocycles, 48(7), 1313–1317. https://doi.org/10.3987/com-98-8148 Comins, D. L., Zhang, Y. M., & Zheng, X. L. (1998). Photochemical reactions of chiral 2,3-dihydro-4(1H)-pyridones: asymmetric synthesis of (-)-perhydrohistrionicotoxin. CHEMICAL COMMUNICATIONS, (22), 2509–2510. https://doi.org/10.1039/a807448h Comins, D. L., Joseph, S. P., Hong, H., Alawar, R. S., Foti, C. J., Zhang, Y. M., … GuerraWeltzien, M. (1997, March). Asymmetric synthesis and synthetic utility of 2,3-dihydro-4-pyridones. PURE AND APPLIED CHEMISTRY, Vol. 69, pp. 477–481. https://doi.org/10.1351/pac199769030477 Comins, D. L., Thakker, P. M., Baevsky, M. F., & Badawi, M. M. (1997). Chiral auxiliary mediated Pictet-Spengler reactions - Asymmetric syntheses of (-)-laudanosine, (+)-glaucine and (-)-xylopinine. TETRAHEDRON, 53(48), 16327–16340. https://doi.org/10.1016/S0040-4020(97)01018-1 Comins, D. L., LaMunyon, D. H., & Chen, X. H. (1997). Enantiopure N-acyldihydropyridones as synthetic intermediates: Asymmetric syntheses of indolizidine alkaloids (-)-205A, (-)-207A, and (-)-235B. JOURNAL OF ORGANIC CHEMISTRY, 62(23), 8182–8187. https://doi.org/10.1021/jo971448u Comins, D. L., Chen, X. H., & Morgan, L. A. (1997). Enantiopure N-acyldihydropyridones as synthetic intermediates: Asymmetric synthesis of (-)-septicine and (-)-tylophorine. JOURNAL OF ORGANIC CHEMISTRY, 62(21), 7435–7438. https://doi.org/10.1021/jo9711495 Comins, D. L. (1996). Method of making asymmetric DE ring intermediates for the synthesis of camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L. (1996). Method of making asymmetric DE ring intermediates for the synthesis of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L. (1995). 14-halo-camptothecins. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baevsky, M. F. (1995). Camptothecin intermediates and method of making camptothecin and comptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L. (1995). Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baevsky, M. F. (1995). Method of making intermediates for camptothecin and its analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1994). Process for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baevsky, M. F. (1994). Pyridinecarboxaldehyde D-ring intermediates useful for the synthesis of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1993). Alkoxymethylpyridine d-ring intermediates useful for the synthesis of camptpthecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1993). Alkylpyridone DE ring intermediates useful for the manufacture of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1993). Camptothecin intermediate and method of making camptothecin intermediates. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1993). Camptothecin intermediates and method of making same. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Salvador, J. M. (1993). Cycloalkyl-based chiral auxiliaries and method making the same. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baevsky, M. F. (1993). D ring intermediates for the synthesis of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1993). Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1993). Methods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1993). Optically pure D,E ring intermediates useful for the synthesis of camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. Comins, D. L., & Baesky, M. F. (1992). Intermediates and method of making camptothecin and camptothecin analogs. Washington, DC: U.S. Patent and Trademark Office. COMINS, D. L., & DEHGHANI, A. (1992). PYRIDINE-DERIVED TRIFLATING REAGENTS - AN IMPROVED PREPARATION OF VINYL TRIFLATES FROM METALLO ENOLATES. TETRAHEDRON LETTERS, 33(42), 6299–6302. https://doi.org/10.1016/S0040-4039(00)60957-7