Dashuai Zhu

Wang, Z., Hu, S., Popowski, K. D., Liu, S., Zhu, D., Mei, X., … Cheng, K. (2024). Inhalation of ACE2-expressing lung exosomes provides prophylactic protection against SARS-CoV-2. NATURE COMMUNICATIONS, 15(1). https://doi.org/10.1038/s41467-024-45628-x

Wang, Z., Li, Z., Shi, W., Zhu, D., Hu, S., Dinh, P.-U. C., & Cheng, K. (2023). A SARS-CoV-2 and influenza double hit vaccine based on RBD-conjugated inactivated influenza A virus. SCIENCE ADVANCES, 9(25). https://doi.org/10.1126/sciadv.abo4100

Mei, X., Li, J., Wang, Z., Zhu, D., Huang, K., Hu, S., … Cheng, K. (2023). An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection. Nature Materials, 2. https://doi.org/10.1038/s41563-023-01475-7

Wang, X., Hu, S., Zhu, D., Li, J., Cheng, K., & Liu, G. (2023). Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials. NANO RESEARCH, 16(5), 7248–7259. https://doi.org/10.1007/s12274-023-5374-3

Zhu, D., Liu, S., Huang, K., Li, J., Mei, X., Li, Z., & Cheng, K. (2023). Intrapericardial long non-coding RNA–<i>Tcf21</i> antisense RNA inducing demethylation administration promotes cardiac repair. European Heart Journal, 44(19), 1748–1760. https://doi.org/10.1093/eurheartj/ehad114

Luo, L., Li, Y., Bao, Z., Zhu, D., Chen, G., Li, W., … Li, Z. (2023, September 15). Pericardial Delivery of SDF-1 α Puerarin Hydrogel Promotes Heart Repair and Electrical Coupling. ADVANCED MATERIALS, Vol. 9. https://doi.org/10.1002/adma.202302686

Zhang, Y., Zhu, D., Wei, Y., Wu, Y., Cui, W., Liuqin, L., … Zhao, Q. (2022). Corrigendum to ‘A collagen hydrogel loaded with HDAC7-derived peptide promotes the regeneration of infarcted myocardium with functional improvement in a rodent model’ [Acta Biomaterialia 2019, 86, 223-234] (Acta Biomaterialia (2019) 86 (223–234), (S174270611930042X), (10.1016/j.actbio.2019.01.022)). Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2022.03.049

Fan, M., Li, H., Shen, D., Wang, Z., Liu, H., Zhu, D., … Li, Z. (2022, September 4). Decoy Exosomes Offer Protection Against Chemotherapy-Induced Toxicity. ADVANCED SCIENCE, Vol. 9. https://doi.org/10.1002/advs.202203505

Hu, S., Zhu, D., Li, Z., & Cheng, K. (2022, September 23). Detachable Microneedle Patches Deliver Mesenchymal Stromal Cell Factor-Loaded Nanoparticles for Cardiac Repair. ACS NANO, Vol. 9. https://doi.org/10.1021/acsnano.2c03060

Wang, Z., Popowski, K. D., Zhu, D., Abad, B. L. de J., Wang, X., Liu, M., … Cheng, K. (2022, July 4). Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine. NATURE BIOMEDICAL ENGINEERING, Vol. 7. https://doi.org/10.1038/s41551-022-00902-5

Popowski, K. D., Moatti, A., Scull, G., Silkstone, D., Lutz, H., López de Juan Abad, B., … Cheng, K. (2022). Inhalable dry powder mRNA vaccines based on extracellular vesicles. Matter, 5(9), 2960–2974. https://doi.org/10.1016/j.matt.2022.06.012

Zhu, D., Liu, S., Huang, K., Wang, Z., Hu, S., Li, J., … Cheng, K. (2022). Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3. CIRCULATION RESEARCH, 131(10), E135–E150. https://doi.org/10.1161/CIRCRESAHA.122.321384

Li, J., Lv, Y., Zhu, D., Mei, X., Huang, K., Wang, X., … Wang, J. (2022). Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction. CHEMICAL ENGINEERING JOURNAL, 427. https://doi.org/10.1016/j.cej.2021.131581

Cheng, G., Zhu, D., Huang, K., & Caranasos, T. G. (2022). Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 169, 113–121. https://doi.org/10.1016/j.yjmcc.2022.04.020

Zhang, C., Zhang, W., Zhu, D., Li, Z., Wang, Z., Li, J., … Zhong, B. (2022). Nanoparticles functionalized with stem cell secretome and CXCR4-overexpressing endothelial membrane for targeted osteoporosis therapy. JOURNAL OF NANOBIOTECHNOLOGY, 20(1). https://doi.org/10.1186/s12951-021-01231-6

Yao, J., Huang, K., Zhu, D., Chen, T., Jiang, Y., Zhang, J., … Cheng, K. (2021). A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction. ACS NANO, 15(7), 11099–11111. https://doi.org/10.1021/acsnano.1c00628

Mei, X., Zhu, D., Li, J., Huang, K., Hu, S., Li, Z., … Cheng, K. (2021). A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs. MED, 2(11), 1253-+. https://doi.org/10.1016/j.medj.2021.10.001

Zhang, S., Zhu, D., Li, Z., Huang, K., Hu, S., Lutz, H., … Cheng, K. (2021). A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency. THERANOSTICS, 11(18), 8894–8908. https://doi.org/10.7150/thno.61690

Xie, M., Li, J., Zhang, S., Zhu, D., Mei, X., Wang, Z., … Cheng, K. (2021). A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse. BIOACTIVE MATERIALS, 6(6), 1777–1788. https://doi.org/10.1016/j.bioactmat.2020.11.031

Zhang, S., Zhu, D., Mei, X., Li, Z., Li, J., Xie, M., … Cheng, K. (2021). [Review of Advances in biomaterials and regenerative medicine for primary ovarian insufficiency therapy]. BIOACTIVE MATERIALS, 6(7), 1957–1972. https://doi.org/10.1016/j.bioactmat.2020.12.008

Li, J., Hu, S., Zhu, D., Huang, K., Mei, X., Abad, B. L. de J., & Cheng, K. (2021). [Review of All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8). https://doi.org/10.1161/JAHA.120.020402

Chingale, M., Zhu, D., Cheng, K., & Huang, K. (2021). Bioengineering Technologies for Cardiac Regenerative Medicine. Frontiers in Bioengineering and Biotechnology, 9. https://doi.org/10.3389/fbioe.2021.681705

Liu, M., Lutz, H., Zhu, D., Huang, K., Li, Z., Dinh, P.-U. C., … Cheng, K. (2021). Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury. Advanced Science, 8(1). https://doi.org/10.1002/advs.202002127

Zhu, D., & Cheng, K. (2021). [Review of Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out?]. CELLS, 10(3). https://doi.org/10.3390/cells10030641

Li, Z., Wang, Z., Dinh, P.-U. C., Zhu, D., Popowski, K. D., Lutz, H., … Cheng, K. (2021). Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19. Nature Nanotechnology, 6(8), 942–951. https://doi.org/10.1038/s41565-021-00923-2

Hu, S., Li, Z., Shen, D., Zhu, D., Huang, K., Su, T., … Cheng, K. (2021). Exosome-eluting stents for vascular healing after ischaemic injury. NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188. https://doi.org/10.1038/s41551-021-00705-0

Wang, X., Hu, S., Li, J., Zhu, D., Wang, Z., Cores, J., … Huang, K. (2021). Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair. ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779. https://doi.org/10.1021/acsami.1c08044

Li, Z., Zhu, D., Hui, Q., Bi, J., Yu, B., Huang, Z., … Wang, X. (2021). Injection of ROS-Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair. ADVANCED FUNCTIONAL MATERIALS, 31(15). https://doi.org/10.1002/adfm.202004377

Zhu, D., Li, Z., Huang, K., Caranasos, T. G., Rossi, J. S., & Cheng, K. (2021). Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair. NATURE COMMUNICATIONS, 12(1). https://doi.org/10.1038/s41467-021-21682-7

Zhu, D., Hou, J., Qian, M., Jin, D., Hao, T., Pan, Y., … Zhao, Q. (2021). Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery. Nature Communications, 12(1). https://doi.org/10.1038/s41467-021-24804-3

Hu, S., Wang, X., Li, Z., Zhu, D., Cores, J., Wang, Z., … Cheng, K. (2021). Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury. NANO TODAY, 39. https://doi.org/10.1016/j.nantod.2021.101210

Hu, S., Li, Z., Shen, D., Zhu, D., Huang, K., Su, T., … Cheng, K. (2021). Publisher Correction: Exosome-eluting stents for vascular healing after ischaemic injury. Nature Biomedical Engineering, 5(10), 1239. https://doi.org/10.1038/s41551-021-00727-8

Liu, Q., Guo, X., Huang, Z., He, Q., Zhu, D., Zhang, S., … Feng, X. (2020). Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice. Behavioural Brain Research, 383. https://doi.org/10.1016/j.bbr.2020.112539

Wang, H., Shang, Y., Chen, X., Wang, Z., Zhu, D., Liu, Y., … Chen, X. (2020). Delivery of mscs with a hybrid β-sheet peptide hydrogel consisting igf-1c domain and d-form peptide for acute kidney injury therapy. International Journal of Nanomedicine, 15, 4311–4324. https://doi.org/10.2147/IJN.S254635

Zhang, S., Zhang, S., Zhu, D., Jiao, Z., Zhao, X., Sun, M., … Feng, X. (2020). Effects of 17β-trenbolone exposure on sex hormone synthesis and social behaviours in adolescent mice. Chemosphere, 245. https://doi.org/10.1016/j.chemosphere.2019.125679

Liang, H., Li, Z., Ren, Z., Jia, Q., Guo, L., Li, S., … Cheng, K. (2020). Light-triggered NO-releasing nanoparticles for treating mice with liver fibrosis. NANO RESEARCH, 13(8), 2197–2202. https://doi.org/10.1007/s12274-020-2833-6

Midgley, A. C., Wei, Y., Zhu, D., Gao, F., Yan, H., Khalique, A., … Kong, D. (2020). Multifunctional natural polymer nanoparticles as antifibrotic gene carriers for CKD therapy. Journal of the American Society of Nephrology, 31(10), 2292–2311. https://doi.org/10.1681/ASN.2019111160

Zhang, R., Luo, W., Zhang, Y., Zhu, D., Midgley, A. C., Song, H., … Huang, X. (2020). Particle-based artificial three-dimensional stem cell spheroids for revascularization of ischemic diseases. Science Advances, 6(19). https://doi.org/10.1126/sciadv.aaz8011

Zhang, C., Shang, Y., Chen, X., Midgley, A. C., Wang, Z., Zhu, D., … Chen, X. (2020). Supramolecular Nanofibers Containing Arginine-Glycine-Aspartate (RGD) Peptides Boost Therapeutic Efficacy of Extracellular Vesicles in Kidney Repair. ACS Nano, 14(9), 12133–12147. https://doi.org/10.1021/acsnano.0c05681

Yan, H., Mi, X., Midgley, A. C., Du, X., Huang, Z., Wei, T., … Wang, K. (2020). Targeted Repair of Vascular Injury by Adipose-Derived Stem Cells Modified with P-Selectin Binding Peptide. Advanced Science, 7(11). https://doi.org/10.1002/advs.201903516

Liu, Q., Zhang, S., Zhu, D., Tang, X., Che, Y., & Feng, X. (2020). The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice. Behavioural Brain Research, 379. https://doi.org/10.1016/j.bbr.2019.112337

Zhang, Y., Zhu, D., Wei, Y., Wu, Y., Cui, W., Liuqin, L., … Zhao, Q. (2019). A collagen hydrogel loaded with HDAC7-derived peptide promotes the regeneration of infarcted myocardium with functional improvement in a rodent model. Acta Biomaterialia, 86, 223–234. https://doi.org/10.1016/j.actbio.2019.01.022

Wang, H., Shang, Y., Chen, X., Wang, Z., Zhu, D., Liu, Y., … Chen, X. (2019). Delivery of MSCs with a Hybrid β-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy. SSRN. https://doi.org/10.2139/ssrn.3485132

Qi, H., Li, Y., Yun, H., Zhang, T., Huang, Y., Zhou, J., … Yang, R. (2019). Lactobacillus maintains healthy gut mucosa by producing L-Ornithine. Communications Biology, 2(1). https://doi.org/10.1038/s42003-019-0424-4

Li, X., Liu, Q., Zhu, D., Che, Y., & Feng, X. (2019). Preparation of levodopa-loaded crystalsomes through thermally induced crystallization reverses functional deficits in Parkinsonian mice. Biomaterials Science, 7(4), 1623–1631. https://doi.org/10.1039/c8bm01098f

Liu, Q., Zhu, D., Jiang, P., Tang, X., Lang, Q., Yu, Q., … Feng, X. (2019). Resveratrol synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson disease in mice. Behavioural Brain Research, 367, 10–18. https://doi.org/10.1016/j.bbr.2019.03.043

Hou, J., Pan, Y., Zhu, D., Fan, Y., Feng, G., Wei, Y., … Zhao, Q. (2019). Targeted delivery of nitric oxide via a ‘bump-and-hole’-based enzyme–prodrug pair. Nature Chemical Biology, 15(2), 151–160. https://doi.org/10.1038/s41589-018-0190-5

Feng, G., Li, H., Zhu, D., Zhang, Y., Song, G., Zhang, Z., … Yao, X. (2018). Expression and clinical significance of CXC-chemokine ligand 5 in renal cell carcinoma. Chinese Journal of Clinical Oncology, 45(16), 838–843. https://doi.org/10.3969/j.issn.1000-8179.2018.16.636

Shafiq, M., Zhang, Y., Zhu, D., Zhao, Z., Kim, D.-H., Kim, S. H., & Kong, D. (2018). In situ cardiac regeneration by using neuropeptide substance P and IGF-1C peptide eluting heart patches. Regenerative Biomaterials, 5(5), 303–316. https://doi.org/10.1093/rb/rby021

Zhang, S., Liu, Y., Zhang, X., Zhu, D., Qi, X., Cao, X., … Li, Z. (2018). Prostaglandin E<sub>2</sub> hydrogel improves cutaneous wound healing via M2 macrophages polarization. Theranostics, 8(19), 5348–5361. https://doi.org/10.7150/thno.27385

Li, J., Wei, Y., Li, X., Zhu, D., Nie, B., Zhou, J., … Chai, L. (2017). Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis mice. BMC Complementary and Alternative Medicine, 17(1). https://doi.org/10.1186/s12906-016-1526-x

Li, X., Sun, D., Li, X., Zhu, D., Jia, Z., Jiao, J., … Feng, X. (2017). PEGylation corannulene enhances response of stress through promoting neurogenesis. Biomaterials Science, 5(4), 849–859. https://doi.org/10.1039/c7bm00068e

Li, X. Y., Ma, J., Xu, J., Zhu, D. S., Li, A., Che, Y. Z., … Feng, X. Z. (2017). Puerarin and Amlodipine Improvement of d-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression. Neurochemical Research, 42(11), 3268–3278. https://doi.org/10.1007/s11064-017-2366-x

Jia, Z., Yang, C., Jiao, J., Li, X., Zhu, D., Yang, Y., … Feng, X. (2017). Rhein and polydimethylsiloxane functionalized carbon/carbon composites as prosthetic implants for bone repair applications. Biomedical Materials (Bristol), 12(4). https://doi.org/10.1088/1748-605X/aa6e27

Feng, G., Zhang, J., Li, Y., Nie, Y., Zhu, D., Wang, R., … Li, Z. (2016). IGF-1 C domain-modified hydrogel enhances cell therapy for AKI. Journal of the American Society of Nephrology, 27(8), 2357–2369. https://doi.org/10.1681/ASN.2015050578