@article{kamleh_khosa_dewey_verbrugghe_stone_2021, title={Ontario Veterinary College First-Year Veterinary Students' Perceptions of Companion Animal Nutrition and Their Own Nutrition: Implications for a Veterinary Nutrition Curriculum}, volume={48}, ISSN={["1943-7218"]}, DOI={10.3138/jvme.0918-113r1}, abstractNote={ Extant research shows veterinarians face increasing challenges in discussing nutrition with clients despite receiving professional nutrition education in the veterinary medical curriculum. This article’s aim is to elicit student veterinarians’ baseline nutrition-related perceptions and nutrition information-seeking behaviors at the time of entering veterinary school. Participants were newly enrolled veterinary students at the Ontario Veterinary College ( n = 120). Focus group discussions ( n = 19) informed the design of an online questionnaire capturing students’ demographics and perceptions of their own and their pets’ nutrition. Students reported being influenced by individual factors (e.g., time), social networks (e.g., family), and surrounding environment (e.g., cost, contradictory media messages). Overall, 58% of students considered themselves knowledgeable about pet nutrition when commencing veterinary school, with 71% prioritizing their pets’ diets as much as their own. Students’ confidence in finding pet nutrition information was correlated with perceived accessibility ( r = .76, p = .001) and perceived quantity of information available on pet nutrition ( r = .83, p = .001), but not quality of information ( r = .13, p = .03). In general, students relied on and trusted veterinarians for nutrition advice. However, 94% of students mistrusted pet food companies’ motivations. Our data support that students entering veterinary school have their own perceptions on pet nutrition that impact nutrition education, suggesting this as an important consideration in the design and delivery of a veterinary nutrition curriculum. Veterinary medical faculty should be encouraged to discuss baseline nutrition information and address any misconceptions to prepare students for future consultations with clients. }, number={1}, journal={JOURNAL OF VETERINARY MEDICAL EDUCATION}, author={Kamleh, May K. and Khosa, Deep K. and Dewey, Cate E. and Verbrugghe, Adronie and Stone, Elizabeth A.}, year={2021}, month={Feb}, pages={71–83} } @article{nielson_kamleh_conlon_mcwhirter_stone_khosa_2021, title={Understanding Incoming Canadian and US Veterinary Students' Attitudes and Perceptions of Their Dietary Habits and Levels of Physical Activity}, volume={48}, ISSN={["1943-7218"]}, DOI={10.3138/jvme-2020-0065}, abstractNote={ As critical components of individual well-being, nutrition and physical activity have important physical and psychological implications. Veterinary students face demanding schedules and potentially high rates of psychological distress. Though veterinary students’ strategies for healthy eating have been explored, factors influencing their ability to achieve a healthy diet are less understood. This study assesses incoming veterinary students’ perceived attitudes to their dietary habits and physical activity levels. Incoming students ( n = 322) at five Canadian and five randomly selected US veterinary schools completed a questionnaire inquiring about demographic information, dietary attitudes and habits, and activity levels. More than half (58%) of students perceived their diet to be moderately healthy. A desire to feel better and have more energy was the most reported (79%) motivating factor to modifying personal eating habits and was significantly associated with improved odds of having a perceived healthy diet ( OR = 2.22, p < .024). A busy lifestyle was perceived as a barrier to changing current eating habits by 92% of respondents. Students reporting a desire to maintain their health ( OR = 3.42, p < .001) and moderate ( OR = 2.81, p < .003) or high ( OR = 2.30, p < .044) routine physical activity levels were also more likely to perceive their diet as healthy. Findings show that incoming veterinary students’ perceptions may influence their goals of achieving a healthy lifestyle. An understanding of incoming veterinary students’ barriers and motivators could be applied in future research to assist students in achieving personalized goals. }, number={6}, journal={JOURNAL OF VETERINARY MEDICAL EDUCATION}, author={Nielson, Shelby A. and Kamleh, May K. and Conlon, Peter D. and McWhirter, Jennifer E. and Stone, Elizabeth A. and Khosa, Deep K.}, year={2021}, month={Dec}, pages={747–755} } @article{kamleh_khosa_verbrugghe_dewey_stone_2020, title={A cross-sectional study of pet owners' attitudes and intentions towards nutritional guidance received from veterinarians}, volume={187}, ISSN={["2042-7670"]}, DOI={10.1136/vr.105604}, abstractNote={Background Beliefs of pet owners strongly influence their decision-making surrounding their pets’ diet. Thus, nutritional guidance is an essential component of veterinary practice and integral to managing rising rates of pet obesity. This study examined pet owners’ trust of, perceived effectiveness of, and intentions to follow nutritional guidance received from their veterinarian in managing their pets’ diet. Methods A cross-sectional study of 1402 dog and cat owners in the USA and Canada was conducted using an online questionnaire tool. Data were analysed using descriptive statistics and logistic regression modelling. Results Clients are concerned about the effectiveness of veterinary nutrition recommendations. Cat owners were more likely than dog owners to consider the nutritional guidance they receive from veterinarians effective for their pets’ diet (1.75, P=0.04). Length of pet ownership, feeding dry diets and frequency of veterinary visits were all positively associated with owners considering veterinary nutritional guidance to be effective in managing pets’ diet. Conclusion Identifying these perspectives can aid in developing strategies to provide nutrition support to pet owners to improve their perceptions of, self-efficacy with, and compliance with veterinary nutrition recommendations.}, number={12}, journal={VETERINARY RECORD}, author={Kamleh, May and Khosa, Deep K. and Verbrugghe, Adronie and Dewey, Cate E. and Stone, Elizabeth}, year={2020}, month={Dec} } @article{stone_reimann_greenhill_dewey_2018, title={Milestone Educational Planning Initiatives in Veterinary Medical Education: Progress and Pitfalls}, volume={45}, ISSN={["1943-7218"]}, DOI={10.3138/jvme.1116-181r1}, abstractNote={ Three milestone educational planning initiatives engaged the veterinary medical profession in the United States and Canada between 1987 and 2011, namely the Pew National Veterinary Education Program, the Foresight Project, and the North American Veterinary Medical Education Consortium. In a quantitative study, we investigated the impact of these initiatives on veterinary medical education through a survey of academic leaders (deans, previous deans, and associate deans for academics from veterinary medical schools that are members of the Association of American Veterinary Medical Colleges) to assess their perspectives on the initiatives and eight recommendations that were common to all three initiatives. Two of the recommendations have in effect been implemented: enable students to elect in-depth instruction and experience within a practice theme or discipline area (tracking), and increase the number of graduating veterinarians. For three of the recommendations, awareness of the issues has increased but substantial progress has not been made: promote diversity in the veterinary profession, develop a plan to reduce student debt, and develop a North American strategic plan. Lastly, three recommendations have not been accomplished: emphasize use of information more than fact recall, share educational resources to enable a cost-effective education, and standardize core admissions requirements. The educational planning initiatives did provide collaborative opportunities to discuss and determine what needs to change within veterinary medical education. Future initiatives should explore how to avoid and overcome obstacles to successful implementation. }, number={3}, journal={JOURNAL OF VETERINARY MEDICAL EDUCATION}, author={Stone, Elizabeth A. and Reimann, Jessica and Greenhill, Lisa M. and Dewey, Cate E.}, year={2018}, pages={388–404} } @article{morozova_ayroles_jordan_duncan_carbone_lyman_stone_govindaraju_ellison_mackay_et al._2009, title={Alcohol Sensitivity in Drosophila: Translational Potential of Systems Genetics}, volume={183}, ISSN={["1943-2631"]}, DOI={10.1534/genetics.109.107490}, abstractNote={AbstractIdentification of risk alleles for human behavioral disorders through genomewide association studies (GWAS) has been hampered by a daunting multiple testing problem. This problem can be circumvented for some phenotypes by combining genomewide studies in model organisms with subsequent candidate gene association analyses in human populations. Here, we characterized genetic networks that underlie the response to ethanol exposure in Drosophila melanogaster by measuring ethanol knockdown time in 40 wild-derived inbred Drosophila lines. We associated phenotypic variation in ethanol responses with genomewide variation in gene expression and identified modules of correlated transcripts associated with a first and second exposure to ethanol vapors as well as the induction of tolerance. We validated the computational networks and assessed their robustness by transposon-mediated disruption of focal genes within modules in a laboratory inbred strain, followed by measurements of transcript abundance of connected genes within the module. Many genes within the modules have human orthologs, which provides a stepping stone for the identification of candidate genes associated with alcohol drinking behavior in human populations. We demonstrated the potential of this translational approach by identifying seven intronic single nucleotide polymorphisms of the Malic Enzyme 1 (ME1) gene that are associated with cocktail drinking in 1687 individuals of the Framingham Offspring cohort, implicating that variation in levels of cytoplasmic malic enzyme may contribute to variation in alcohol consumption.}, number={2}, journal={GENETICS}, author={Morozova, Tatiana V. and Ayroles, Julien F. and Jordan, Katherine W. and Duncan, Laura H. and Carbone, Mary Anna and Lyman, Richard E. and Stone, Eric A. and Govindaraju, Diddahally R. and Ellison, R. Curtis and Mackay, Trudy F. C. and et al.}, year={2009}, month={Oct}, pages={733–745} } @article{harbison_carbone_ayroles_stone_lyman_mackay_2009, title={Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep}, volume={41}, ISSN={["1546-1718"]}, DOI={10.1038/ng.330}, abstractNote={Trudy Mackay and colleagues measure sleep phenotypes in 40 wild-derived Drosophila lines, and report candidate genes and transcriptional networks associated with sleep regulation. Sleep disorders are common in humans, and sleep loss increases the risk of obesity and diabetes1. Studies in Drosophila2,3 have revealed molecular pathways4,5,6,7 and neural tissues8,9,10 regulating sleep; however, genes that maintain genetic variation for sleep in natural populations are unknown. Here, we characterized sleep in 40 wild-derived Drosophila lines and observed abundant genetic variation in sleep architecture. We associated sleep with genome-wide variation in gene expression11 to identify candidate genes. We independently confirmed that molecular polymorphisms in Catsup (Catecholamines up) are associated with variation in sleep and that P-element mutations in four candidate genes affect sleep and gene expression. Transcripts associated with sleep grouped into biologically plausible genetically correlated transcriptional modules. We confirmed co-regulated gene expression using P-element mutants. Quantitative genetic analysis of natural phenotypic variation is an efficient method for revealing candidate genes and pathways.}, number={3}, journal={NATURE GENETICS}, author={Harbison, Susan T. and Carbone, Mary Anna and Ayroles, Julien F. and Stone, Eric A. and Lyman, Richard F. and Mackay, Trudy F. C.}, year={2009}, month={Mar}, pages={371–375} } @article{ayroles_carbone_stone_jordan_lyman_magwire_rollmann_duncan_lawrence_anholt_et al._2009, title={Systems genetics of complex traits in Drosophila melanogaster}, volume={41}, ISSN={["1546-1718"]}, DOI={10.1038/ng.332}, abstractNote={Trudy Mackay and colleagues present a resource of 40 Drosophila melanogaster wild-derived inbred lines. The authors quantify genome-wide variation in transcript abundance for six ecologically relevant traits, characterize the transcriptome and identify transcriptional modules. Determining the genetic architecture of complex traits is challenging because phenotypic variation arises from interactions between multiple, environmentally sensitive alleles. We quantified genome-wide transcript abundance and phenotypes for six ecologically relevant traits in D. melanogaster wild-derived inbred lines. We observed 10,096 genetically variable transcripts and high heritabilities for all organismal phenotypes. The transcriptome is highly genetically intercorrelated, forming 241 transcriptional modules. Modules are enriched for transcripts in common pathways, gene ontology categories, tissue-specific expression and transcription factor binding sites. The high degree of transcriptional connectivity allows us to infer genetic networks and the function of predicted genes from annotations of other genes in the network. Regressions of organismal phenotypes on transcript abundance implicate several hundred candidate genes that form modules of biologically meaningful correlated transcripts affecting each phenotype. Overlapping transcripts in modules associated with different traits provide insight into the molecular basis of pleiotropy between complex traits.}, number={3}, journal={NATURE GENETICS}, author={Ayroles, Julien F. and Carbone, Mary Anna and Stone, Eric A. and Jordan, Katherine W. and Lyman, Richard F. and Magwire, Michael M. and Rollmann, Stephanie M. and Duncan, Laura H. and Lawrence, Faye and Anholt, Robert R. H. and et al.}, year={2009}, month={Mar}, pages={299–307} } @article{kyles_hardie_wooden_adin_stone_gregory_mathews_cowgill_vaden_nyland_et al._2005, title={Clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in cats with ureteral calculi: 163 cases (1984-2002)}, volume={226}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2005.226.932}, abstractNote={AbstractObjective—To determine clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in cats with ureteral calculi.Design—Retrospective study.Animals—163 client-owned cats.Procedure—Medical records were reviewed, and information on signalment, history, clinical signs, and results of clinicopathologic testing and diagnostic imaging was obtained.Results—The number of cats in which ureterolithiasis was diagnosed each year increased progressively during the study period. Clinical signs tended to be nonspecific and included inappetence, vomiting, lethargy, and weight loss. A combination of survey radiography and abdominal ultrasonography revealed ureteral calculi in 66 of 73 (90%) cats in which the diagnosis was confirmed at surgery or necropsy. Ultrasonography revealed that ureteral calculi were causing ureteral obstruction in 143 of 155 (92%) cats. One hundred thirty-four of 162 (83%) cats had azotemia, 84 of 156 (54%) had hyperphosphatemia, and 22 of 152 (14%) had hypercalcemia. Urinary tract infection was documented in 10 of 119 (8%). Fifty-eight of 76 (76%) cats with unilateral ureterolithiasis had azotemia and 33 (43%) had hyperphosphatemia, indicating impairment of renal function in the contralateral kidney or prerenal azotemia. Ultrasonographic imaging of the contralateral kidney in cats with unilateral ureteral calculi suggested that preexisting renal parenchymal disease was common in cats with ureterolithiasis. Ninety-one of 93 (98%) ureteral calculi contained calcium oxalate.Conclusions and Clinical Relevance—Results suggest that abdominal imaging should be performed in all cats with chronic nonspecific signs or with acute or chronic renal failure to rule out ureterolithiasis. Preexisting renal disease may be common in cats with ureteral calculi. (J Am Vet Med Assoc2005;226: 932–936)}, number={6}, journal={JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Kyles, AE and Hardie, EM and Wooden, BG and Adin, CA and Stone, EA and Gregory, CR and Mathews, KG and Cowgill, LD and Vaden, S and Nyland, TG and et al.}, year={2005}, month={Mar}, pages={932–936} } @article{kyles_hardie_wooden_adin_stone_gregory_mathews_cowgill_vaden_nyland_et al._2005, title={Management and outcome of cats with ureteral calculi: 153 cases (1984-2002)}, volume={226}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2005.226.937}, abstractNote={AbstractObjective—To determine outcome of medical and surgical treatment in cats with ureteral calculi.Design—Retrospective study.Animals—153 cats.Procedure—Medical records were reviewed. Owners and referring veterinarians were contacted for follow-up information.Results—All cats were initially treated medically before a decision was made to perform surgery. Medical treatment included parenteral administration of fluids and diuretics to promote urine production and passage of the ureteral calculus and supportive treatment for renal failure. Ureteral calculi in the proximal portion of the ureter were typically removed by ureterotomy, whereas ureteral calculi in the distal portion of the ureter were more likely to be removed by partial ureterectomy and ureteroneocystostomy. Ureterotomy could be performed without placement of a nephrostomy tube for postoperative urine diversion. Postoperative complication rate and perioperative mortality rate were 31% and 18%, respectively. The most common postoperative complications were urine leakage and persistent ureteral obstruction after surgery. Chronic renal failure was common at the time of diagnosis and continued after treatment, with serum creatinine concentration remaining greater than the upper reference limit in approximately half the cats. Twelve-month survival rates after medical and surgical treatment were 66% and 91%, respectively, with a number of cats dying of causes related to urinary tract disorders, including ureteral calculus recurrence and worsening of chronic renal failure.Conclusions and Clinical Relevance—Results suggest that medical and surgical management of ureteral calculi in cats are associated with high morbidity and mortality rates. Treatment can stabilize renal function, although many surviving cats will continue to have impaired renal function. (J Am Vet Med Assoc2005;226:937–944)}, number={6}, journal={JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Kyles, AE and Hardie, EM and Wooden, BG and Adin, CA and Stone, EA and Gregory, CR and Mathews, KG and Cowgill, LD and Vaden, S and Nyland, TG and et al.}, year={2005}, month={Mar}, pages={937–944} } @article{stone_weisert_2004, title={Introducing a course in veterinary medicine and literature into a veterinary curriculum}, volume={224}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2004.224.1249}, number={8}, journal={JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Stone, EA and Weisert, HA}, year={2004}, month={Apr}, pages={1249–1253} } @article{seguin_vaden_altier_stone_levine_2003, title={Persistent urinary tract infections and reinfections in 100 dogs (1989-1999)}, volume={17}, ISSN={["0891-6640"]}, DOI={10.1892/0891-6640(2003)017<0622:PUTIAR>2.3.CO;2}, number={5}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Seguin, MA and Vaden, SL and Altier, C and Stone, E and Levine, JF}, year={2003}, pages={622–631} } @article{stone_robertson_metcalf_2002, title={The effect of nephrotomy on renal function and morphology in dogs}, volume={31}, ISSN={["0161-3499"]}, DOI={10.1053/jvet.2002.33595}, abstractNote={Objective— To determine whether bisection or intersegmental nephrotomy adversely affects glomerular filtration rate (GFR) and whether bisection nephrotomy has less adverse effect than intersegmental nephrotomy.Study design— Dogs assigned to 5 groups of 3 dogs each, depending on time of euthanasia at postoperative day 1, 4, 8, 15, or 29.Animals— Fifteen healthy adult intact female dogs.Methods— Within 4 days of total and single kidney GFR measurements using technetium Tc 99m‐DTPA, left intersegmental nephrotomy and right bisection nephrotomy were performed. The GFR measurements were repeated the day before dogs were killed except for the day 1 group. Histologic examination was performed on kidneys harvested from day 1, 4, 8, and 29 groups. Severity of lesions was scored on a 0 to 4 scale. Single kidney GFR was compared in each kidney before and after nephrotomy. Histologic and GFR changes were compared between bisection and intersegmental nephrotomy kidneys for each time period.Results and Conclusions— Three days after surgery, total GFR was increased from baseline by 176%, with no difference in percent change in single kidney GFR between intersegmental and bisection nephrotomy. By day 7, total and single kidney GFR were not different than baseline. Bisection nephrotomy caused more intrarenal hemorrhage and cortical infarction and inflammation than intersegmental nephrotomy. By 4 weeks, no significant histologic differences were observed between the 2 techniques.Clinical relevance— Neither intersegmental nor bisection nephrotomy adversely affected GFR. As intersegmental nephrotomy requires additional surgical manipulation and time, bisection nephrotomy is the technique of choice for nephrotomy in dogs.}, number={4}, journal={VETERINARY SURGERY}, author={Stone, EA and Robertson, JL and Metcalf, MR}, year={2002}, pages={391–397} } @inbook{stone_kyles_2000, title={Diagnosis and management of ureteral obstruction}, ISBN={0721655238}, booktitle={Kirk's current veterinary therapy : small animal practice (13th Ed.)}, publisher={Philadelphia, PA : W.B. Saunders}, author={Stone, E. A. and Kyles, A. E.}, year={2000}, pages={868} } @inbook{stone_gookin_2000, title={Indications for nephrectomy and nephrotomy}, ISBN={0721655238}, booktitle={Kirk's current veterinary therapy : small animal practice (13th Ed.)}, publisher={Philadelphia, PA : W.B. Saunders}, author={Stone, E. A. and Gookin, J.}, year={2000}, pages={866} } @article{gookin_stone_sharp_2000, title={Urinary incontinence on dogs and cats. I. Measurement of urethral pressure. A review / L'incontinenza urinaria nel cane e nel gatto. Parte I -- profilometria della pressione uretrale}, volume={14}, ISBN={0394-3151}, number={2}, journal={Veterinaria}, author={Gookin, J. L. and Stone, E. A. and Sharp, N. J.}, year={2000}, pages={33} } @article{gookin_stone_sharp_2000, title={Urinary incontinence on dogs and cats. II. Diagnosis and treatment. A review / L'incontinenza urinaria nel cane e nel gatto. Parte II -- diagnosi e trattamento}, volume={14}, ISBN={0394-3151}, number={2}, journal={Veterinaria}, author={Gookin, J. L. and Stone, E. A. and Sharp, N. J.}, year={2000}, pages={43} } @article{nwadike_wilson_stone_2000, title={Use of bilateral temporary nephrostomy catheters for emergency treatment of bilateral ureter transection in a cat}, volume={217}, ISSN={["0003-1488"]}, DOI={10.2460/javma.2000.217.1862}, abstractNote={A 2-year-old Himalayan cat was examined because of 4 days of vomiting, lethargy; and anorexia. The cat had undergone hysterectomy and removal of left ovarian remnants 5 days earlier. Results of laboratory testing and excretory urography were consistent with uremia and bilateral ureteral obstruction. Nephrostomy catheters were placed to drain urine and allow time for physiologic diuresis prior to definitive repair. During the next 2 days, the cat's physiologic status improved greatly. The cat underwent exploratory surgery, and both ureters were found to be ligated. The healthy proximal portions of the ureters were implanted into the bladder. Six months after surgery, the cat was doing well, and excretory urography demonstrated that both ureters were patent. Bilateral obstruction of the ureters is a life-threatening condition that can be difficult to correct in cats. Placement of nephrostomy catheters allows time for improvement in the cat's physiologic status prior to the protracted anesthesia time needed for surgical repair of the ureters.}, number={12}, journal={JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION}, author={Nwadike, BS and Wilson, LP and Stone, EA}, year={2000}, month={Dec}, pages={1862-+} } @article{kyles_stone_gookin_spaulding_clary_wylie_spodnick_1998, title={Diagnosis and surgical management of obstructive ureteral calculi in cats: 11 cases (1993-1996)}, volume={213}, number={8}, journal={Journal of the American Veterinary Medical Association}, author={Kyles, A. E. and Stone, E. A. and Gookin, J. and Spaulding, K. and Clary, E. M. and Wylie, K. and Spodnick, G.}, year={1998}, pages={1150–1156} } @article{hawthorne_dehaan_goring_randall_kennedy_stone_zimmerman_mcabee_1998, title={Recurrent urethral obstruction secondary to idiopathic renal hematuria in a puppy}, volume={34}, ISSN={["0587-2871"]}, DOI={10.5326/15473317-34-6-511}, abstractNote={A seven-month-old, neutered male Catahoula leopard dog cross was presented for recurrent urethral obstruction and intermittent hematuria. After exploratory laparotomy and ventral cystotomy, unilateral idiopathic renal hematuria was diagnosed based on gross observation of hematuria from the left ureteral catheter. The hematuria resolved after nephrectomy of the left kidney. The histopathological diagnosis was multifocal, acute congestion and intratubular hemorrhage. Although idiopathic renal hematuria has been described previously, this puppy was unique because the hematuria caused recurrent, complete urethral obstruction.}, number={6}, journal={JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION}, author={Hawthorne, JC and deHaan, JJ and Goring, RL and Randall, SR and Kennedy, FS and Stone, E and Zimmerman, KM and McAbee, SW}, year={1998}, pages={511–514} } @article{stone_1997, title={Surgical management of urinary tract disease: ureteral calculi in cats and urinary bladder neoplasia in dogs}, volume={19}, number={3, suppl.}, journal={Compendium on Continuing Education for the Practicing Veterinarian}, author={Stone, E. A.}, year={1997}, pages={62–68} } @article{stone_george_gilson_page_1996, title={Partial cystectomy for urinary bladder neoplasia: Surgical technique and outcome in 11 dogs}, volume={37}, ISSN={["0022-4510"]}, DOI={10.1111/j.1748-5827.1996.tb01745.x}, abstractNote={ABSTRACTPartial cystectomy was performed in 11 dogs with bladder neoplasia (10 with transitional cell carcinoma and one with rhabdomyosarcoma). Between 40 and 70 per cent of the bladder was excised during the partial cystectomies. In eight dogs, all the grossly visible tumour was excised but on histopathological examination of the excised tissue, neoplastic tissue was found to extend to the surgical margins in four of these dogs. A ureteral stoma was excised with the tumour in four dogs necessitating ureteral reimplantation; one dog had both ureteral stomas excised and bilateral ureteral reimplantation. The bladder incision dehisced in two dogs, necessitating a second surgery. Six dogs were polla‐kiuric after surgery. Pollakiuria resolved within two months in four dogs and persisted in two dogs. None was incontinent. Local tumour recurrence was suspected in nine dogs based on imaging studies and confirmed in five dogs during post mortem examination. Five dogs were euthanased two to seven months after surgery. Six dogs survived at least one year, two of these dogs remain alive at 17 and 27 months after surgery. It is concluded that partial cystectomy may provide local control of bladder neoplasia.}, number={10}, journal={JOURNAL OF SMALL ANIMAL PRACTICE}, author={Stone, EA and George, TF and Gilson, SD and Page, RL}, year={1996}, month={Oct}, pages={480-&} } @article{stone_1995, title={BIOPSY - PRINCIPLES, TECHNICAL CONSIDERATIONS, AND PITFALLS}, volume={25}, ISSN={["0195-5616"]}, DOI={10.1016/S0195-5616(95)50003-8}, abstractNote={Biopsy is an essential part of the diagnostic workup for cancer patients. Percutaneous, endoscopic, catheter, incisional, and excisional biopsies have different indications, accuracy, and efficacy. Careful attention to biopsy technique will minimize complications and increase the accuracy and efficacy of the biopsy procedure. Intraoperative biopsy and microscopy can be used in selected instances to modify the surgical plan.}, number={1}, journal={VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE}, author={STONE, EA}, year={1995}, month={Jan}, pages={33–45} } @article{schiller_stone_gupta_1993, title={INVITRO LOSS OF TENSILE-STRENGTH AND ELASTICITY OF 5 ABSORBABLE SUTURE MATERIALS IN STERILE AND INFECTED CANINE URINE}, volume={22}, ISSN={["0161-3499"]}, DOI={10.1111/j.1532-950X.1993.tb00383.x}, abstractNote={The loss of breaking strength and elasticity of five absorbable suture materials (polydioxanone [PDS‐II], polyglycolic acid [PGA], polyglactin 910 [PG‐910], polyglyconate [GTMC], and chromic gut) after in vitro incubation in sterile, Escherichia coli‐ and Proteus mirab/tfs‐inoculated canine urine was studied. Biomechanical testing, in a controlled environment, was performed during the 28‐day study period. Polydioxanone and chromic gut retained greater than 90% of their original strengths after 28 days of incubation in sterile urine and 87% of original strengths in E. co//‐inoculated urine. Polyglyconate retained 24% and 18% of original strength, respectively, after incubation in sterile and E. co/i‐inoculated urine for 28 days. Polyglycolic acid and PG‐910 retained less than 30% of original strength in sterile urine and only 7% in E. co/i‐inoculated urine after 21 days of incubation. In P. m/rabi/is‐inoculated urine, loss of tensile strength and elongation was significant for all suture materials. Polyglycolic acid and PG‐910 lost all strength after 24 hours of incubation. Polydioxanone lost all strength after 7 days of incubation, whereas GTMC retained 19% at day 7. Chromic gut retained 78% at day 7 and 16% after 21 days of incubation, however, the absence of normal phagocytic destruction of chromic gut in this in vitro study may have artificially elevated these values. In sterile urine with chemically modified pH, loss of strength and elongation was greater in alkaline urine than in neutral or acidic urine for all types of suture materials.}, number={3}, journal={VETERINARY SURGERY}, author={SCHILLER, TD and STONE, EA and GUPTA, BS}, year={1993}, pages={208–212} } @article{stone_mason_1990, title={Surgery of ectopic ureters: Types, method of correction, and postoperative results}, volume={26}, number={1}, journal={Journal of the American Animal Hospital Association}, author={Stone, E. A. and Mason, L. K.}, year={1990}, pages={81} } @article{edwards_ayroles_stone_carbone_lyman_mackay, title={A transcriptional network associated with natural variation in Drosophila aggressive behavior}, volume={10}, number={7}, journal={Genome Biology}, author={Edwards, A. C. and Ayroles, J. F. and Stone, E. A. and Carbone, M. A. and Lyman, R. F. and Mackay, T. F. C.} } @misc{mackay_stone_ayroles, title={The genetics of quantitative traits: Challenges and prospects}, volume={10}, number={8}, journal={Nature Reviews. Genetics}, author={Mackay, T. F. C. and Stone, E. A. and Ayroles, J. F.}, pages={565–577} }