Works (2)

Updated: July 5th, 2023 14:52

2022 article

Inhibition of experimental autoimmune uveitis by intravitreal AAV-Equine-IL10 gene therapy

Crabtree, E., Uribe, K., Smith, S. M., Roberts, D., Salmon, J. H., Bower, J. J., … Gilger, B. C. (2022, August 18). (A. W. Taylor, Ed.). PLoS ONE, Vol. 17.

Ed(s): A. Taylor

MeSH headings : Animals; Autoimmune Diseases; Dependovirus / genetics; Genetic Therapy; Horses / genetics; Humans; Interleukin-10 / genetics; Interleukin-10 / therapeutic use; Rats; Uveitis
topics (OpenAlex): Virus-based gene therapy research; Herpesvirus Infections and Treatments
TL;DR: Safety and efficacy of AAV8-Equine-IL10 to prevent EAU are demonstrated and support continued exploration of A AV gene therapy for the treatment of equine and perhaps human recurrent uveitis. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 19, 2022

2019 journal article

AAV-mediated expression of HLA-G1/5 reduces severity of experimental autoimmune uveitis

Scientific Reports, 9(1), 19864.

MeSH headings : Animals; Antibodies, Neutralizing / metabolism; Dependovirus / genetics; Female; Genetic Therapy; HLA-G Antigens / genetics; HLA-G Antigens / metabolism; HLA-G Antigens / physiology; Intravitreal Injections; Rats; Uveitis / genetics; Uveitis / metabolism; Uveitis / pathology; Uveitis / therapy
topics (OpenAlex): Immunotherapy and Immune Responses; Herpesvirus Infections and Treatments; Reproductive System and Pregnancy
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 10, 2020

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