Edward E. Large

Works (6)

Updated: July 5th, 2023 15:56

2014 journal article

Caenorhabditis elegans SWI/SNF subunits control sequential developmental stages in the somatic gonad

G3-Genes Genomes Genetics, 4(3), 471–483.

By: E. Large & L. Mathies

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

hunchback and Ikaros-like zinc finger genes control reproductive system development in Caenorhabditis elegans

Developmental Biology, 339(1), 51–64.

By: E. Large & L. Mathies

Source: NC State University Libraries
Added: August 6, 2018

2007 article

Chromatin regulation and sex determination in Caenorhabditis elegans

Large, E. E., & Mathies, L. D. (2007, April 21). Trends in Genetics.

By: E. Large n & L. Mathies n

MeSH headings : Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins / physiology; Chromatin / metabolism; Male; Models, Biological; Models, Genetic; Protein Binding; Sex Determination Processes; Sex Factors; Signal Transduction; Transcription, Genetic; Zinc Fingers
topics (OpenAlex): Genetics, Aging, and Longevity in Model Organisms; Epigenetics and DNA Methylation; Reproductive Biology and Fertility
TL;DR: This research indicates a possible conserved role for these complexes in either GLI-directed gene repression or sex determination, as recent findings implicate two conserved transcription-repressor complexes in the repression of male-specific genes. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 article

Quantification of mucin gene expression in tracheobronchial epithelium of healthy dogs and dogs with chronic bronchitis

Hawkins, E. C., Birkenheuer, A. J., Marr, H. S., Rogala, A. R., Large, E. E., & Adler, K. B. (2007, April 1). American Journal of Veterinary Research, Vol. 68, pp. 435–440.

By: E. Hawkins n , A. Birkenheuer* , H. Marr*, A. Rogala*, E. Large* & K. Adler*

MeSH headings : Animals; Bronchitis, Chronic / metabolism; Bronchitis, Chronic / veterinary; DNA Primers; Dog Diseases / metabolism; Dogs; Evaluation Studies as Topic; Mucins / metabolism; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; RNA, Messenger / metabolism
topics (OpenAlex): Glycosylation and Glycoproteins Research; Tracheal and airway disorders; Neonatal Respiratory Health Research
TL;DR: The ability to measure mucin gene expression from tracheobronchial brushing specimens collected from client-owned dogs during routine bronchoscopy should prove to be a useful tool for the study of bronchitis in dogs and expand the usefulness of airway inflammation in dogs as a model for bronchritis in humans. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2006 article

Cellular composition of bronchial brushings obtained from healthy dogs and dogs with chronic cough and cytologic composition of bronchoalveolar lavage fluid obtained from dogs with chronic cough

Hawkins, E. C., Rogala, A. R., Large, E. E., Bradley, J. M., & Grindem, C. B. (2006, January 1). American Journal of Veterinary Research, Vol. 67, pp. 160–167.

By: E. Hawkins n , A. Rogala*, E. Large*, J. Bradley* & C. Grindem*

MeSH headings : Animals; Bronchi / cytology; Bronchi / pathology; Bronchoalveolar Lavage Fluid / cytology; Bronchoscopy / veterinary; Cough / pathology; Cough / veterinary; Dog Diseases / pathology; Dogs; Goblet Cells / cytology; Leukocyte Count / veterinary; Statistics, Nonparametric
topics (OpenAlex): Respiratory and Cough-Related Research; Asthma and respiratory diseases; Inhalation and Respiratory Drug Delivery
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 article

Molecular Characterization of a Babesia Species Identified in a North American Raccoon

Birkenheuer, A. J., Whittington, J., Neel, J., Large, E., Barger, A., Levy, M. G., & Breitschwerdt, E. B. (2006, April 1). Journal of Wildlife Diseases, Vol. 42, pp. 375–380.

By: A. Birkenheuer n , J. Whittington*, J. Neel n , E. Large n, A. Barger*, M. Levy n, E. Breitschwerdt n 

Contributors: A. Birkenheuer n , J. Whittington*, J. Neel n , E. Large n, A. Barger*, M. Levy n, E. Breitschwerdt n 

author keywords: Babesia; PCR; phylogenetics; piroplasm; Procyon lotor; raccoon; taxonomy
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / parasitology; Babesiosis / transmission; Babesiosis / veterinary; Diagnosis, Differential; Disease Reservoirs / veterinary; Gene Amplification; Humans; Male; Phylogeny; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; RNA, Protozoan / analysis; RNA, Ribosomal, 18S / analysis; Raccoons / parasitology; Zoonoses
topics (OpenAlex): Vector-borne infectious diseases; Vector-Borne Animal Diseases; Viral Infections and Vectors
TL;DR: The data generated in this study can be used to design molecular diagnostic tests for detection of this Babesia sp. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

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