@article{large_mathies_2014, title={Caenorhabditis elegans SWI/SNF subunits control sequential developmental stages in the somatic gonad}, volume={4}, number={3}, journal={G3-Genes Genomes Genetics}, author={Large, E. E. and Mathies, L. D.}, year={2014}, pages={471–483} } @article{large_mathies_2010, title={hunchback and Ikaros-like zinc finger genes control reproductive system development in Caenorhabditis elegans}, volume={339}, number={1}, journal={Developmental Biology}, author={Large, E. E. and Mathies, L. D.}, year={2010}, pages={51–64} } @article{large_mathies_2007, title={Chromatin regulation and sex determination in Caenorhabditis elegans}, volume={23}, ISSN={["1362-4555"]}, DOI={10.1016/j.tig.2007.04.002}, abstractNote={Glioma-associated oncogene (GLI) transcription factors function downstream of the hedgehog signal transduction pathway to regulate the development of many animals. Although the nematode Caenorhabditis elegans lacks a hedgehog pathway, it does have a GLI protein that represses male development in favor of hermaphrodite development. As we discuss here, recent findings implicate two conserved transcription-repressor complexes in the repression of male-specific genes. This research indicates a possible conserved role for these complexes in either GLI-directed gene repression or sex determination.}, number={7}, journal={TRENDS IN GENETICS}, author={Large, Edward E. and Mathies, Laura D.}, year={2007}, month={Jul}, pages={314–317} } @article{hawkins_birkenheuer_marr_rogala_large_adler_2007, title={Quantification of mucin gene expression in tracheobronchial epithelium of healthy dogs and dogs with chronic bronchitis}, volume={68}, ISSN={["1943-5681"]}, DOI={10.2460/ajvr.68.4.435}, abstractNote={Abstract}, number={4}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Hawkins, Eleanor C. and Birkenheuer, Adam J. and Marr, Henry S. and Rogala, Allison R. and Large, Edward E. and Adler, Kenneth B.}, year={2007}, month={Apr}, pages={435–440} } @article{hawkins_rogala_large_bradley_grindem_2006, title={Cellular composition of bronchial brushings obtained from healthy dogs and dogs with chronic cough and cytologic composition of bronchoalveolar lavage fluid obtained from dogs with chronic cough}, volume={67}, ISSN={["1943-5681"]}, DOI={10.2460/ajvr.67.1.160}, abstractNote={Abstract}, number={1}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Hawkins, EC and Rogala, AR and Large, EE and Bradley, JM and Grindem, CB}, year={2006}, month={Jan}, pages={160–167} } @article{birkenheuer_whittington_neel_large_barger_levy_breitschwerdt_2006, title={Molecular characterization of a Babesia species identified in a North American raccoon}, volume={42}, ISSN={["1943-3700"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-33748280658&partnerID=MN8TOARS}, DOI={10.7589/0090-3558-42.2.375}, abstractNote={Piroplasmosis was first described in raccoons (Procyon lotor) in 1926, and the official description of a small piroplasm as Babesia lotori was done in 1981. Babesia microti-like gene sequences have been characterized in raccoons in both North American and Japan. It is well documented that the microscopic appearance of piroplasms does not always accurately predict the genotype and phylogenetic classification. Discrepancies using phenotype to predict genotype have been reported most frequently when evaluating small piroplasms. We amplified and sequenced the full-length 18S rRNA gene from a small piroplasm identified in a raccoon and used this sequence for phylogenetic analyses. Based on these analyses, the organism was placed in the Babesia sensu stricto clade, confirming that it is a true Babesia sp. This documents that at least two Babesia spp. can infect raccoons. The data generated in this study can be used to design molecular diagnostic tests for detection of this Babesia sp., which will be useful for epidemiologic and comparative phylogenetic studies. As piroplasmosis has been documented with increased frequency in humans in recent years, the results of this study will aid in the recognition of zoonotic babesiosis.}, number={2}, journal={JOURNAL OF WILDLIFE DISEASES}, author={Birkenheuer, Adam J. and Whittington, Julia and Neel, Jennifer and Large, Edward and Barger, Anne and Levy, Michael G. and Breitschwerdt, Edward B.}, year={2006}, month={Apr}, pages={375–380} }