Works (45)
Updated: April 16th, 2024 05:00
2024 journal article
The Impact of Inorganic Systems and Photoactive Metal Compounds on Cytochrome P450 Enzymes and Metabolism: From Induction to Inhibition
Biomolecules.
www.mdpi.com (publisher PDF)
Source: ORCID
Added: April 8, 2024
2021 journal article
Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity
Photochemistry and Photobiology, 98(1), 73–84.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Coordination Complexes / chemistry; Coordination Complexes / pharmacology; Ligands; Ruthenium / chemistry; Ruthenium / pharmacology; Singlet Oxygen / chemistry
TL;DR:
The results here are consistent with the earlier findings in that seemingly minor structural modifications on the non‐strained ligand can dramatically modulate the normoxic and hypoxic activity of these strained compounds and that these changes appear to exert a greater influence on photocytotoxicity than singlet oxygen sensitization or rates of photosubstitution in cell‐free conditions would suggest.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: January 28, 2023
2020 journal article
Avobenzone incorporation in a diverse range of Ru(<scp>ii</scp>) scaffolds produces potent potential antineoplastic agents
Dalton Transactions, 49(35), 12161–12167.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Line, Tumor; Coordination Complexes / chemistry; Coordination Complexes / pharmacology; Humans; Ligands; Photochemotherapy; Propiophenones / chemistry; Ruthenium / chemistry; Structure-Activity Relationship
TL;DR:
Four structurally distinct classes of polypyridyl ruthenium complexes containing avobenzone exhibited low micromolar and submicromolar potencies in cancer cells, and were up to 273-fold more active than the parent ligand.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: January 28, 2023
2020 journal article
Bis-tridentate N-Heterocyclic Carbene Ru(II) Complexes are Promising New Agents for Photodynamic Therapy.
Inorganic Chemistry.
TL;DR:
A proof-of-concept approach to make bis-tridentate Ru(II) complexes useful for PDT applications by altering their photophysical properties through the inclusion of N-heterocyclic carbene (NHC) ligands is reported.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2018 journal article
Bacterial Cytological Profiling Reveals the Mechanism of Action of Anticancer Metal Complexes
Molecular Pharmaceutics, 15(8), 3404–3416.
Contributors: Y. Sun *, D. Heidary *, Z. Zhang *, C. Richards * & E. Glazer *
TL;DR:
This study demonstrates E. coli can be used to rapidly distinguish between compounds with disparate mechanisms of action and also for more subtle distinctions within in studies in mammalian cells.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2018 journal article
Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450<inf>BM3</inf> Variant
Biophysical Journal, 115(7), 1251–1263.
Contributors: I. Geronimo *, C. Denning*, D. Heidary *, E. Glazer * & C. Payne *
TL;DR:
Investigation of the binding of drug molecules with different size, charge, polar surface area, and human P450 affinity on the promiscuous R47L/F87V/L188Q/E267V/F81I pentuple mutant of P450BM3 found it stably binds a broad range of substrate and inhibitor types.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2018 journal article
Ru(ii) complexes with diazine ligands: Electronic modulation of the coordinating group is key to the design of "dual action" photoactivated agents
Chemical Communications, 54(88), 12487–12490.
Contributors: D. Havrylyuk* , M. Deshpande*, S. Parkin * & E. Glazer *
TL;DR:
This effect is general, as it is effective with different Ru(ii) structures, and demonstrates that diazine-based drugs are the preferred choice for the development of light-activated dual action Ru(II) agents.
(via Semantic Scholar)
Source: ORCID
Added: January 23, 2023
2018 journal article
Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines
European Journal of Medicinal Chemistry, 156, 790–799.
Contributors: D. Havrylyuk* , B. Howerton*, L. Nease*, S. Parkin *, D. Heidary * & E. Glazer *
author keywords: Cytotoxic; Ruthenium; Cancer; Coordination chemistry; Translation
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Line, Tumor; Coordination Complexes / chemistry; Coordination Complexes / pharmacology; Humans; Hydroxyquinolines / chemistry; Hydroxyquinolines / pharmacology; Ligands; Models, Molecular; Neoplasms / drug therapy; Neoplasms / genetics; Protein Biosynthesis / drug effects; Ruthenium / chemistry; Ruthenium / pharmacology; Structure-Activity Relationship; Transcription, Genetic / drug effects
TL;DR:
The effects were seen at 2-15-fold higher concentrations than those required to observe cytotoxicity, suggesting that prevention of protein synthesis may be a primary, but not the exclusive mechanism for the observed cytotoxic activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: January 29, 2023
2018 journal article
Superior photodynamic effect of carbon quantum dots through both type I and type II pathways: Detailed comparison study of top-down-synthesized and bottom-up-synthesized carbon quantum dots
Carbon, 140, 616–623.
Contributors: T. Pillar-Little*, N. Wanninayake *, L. Nease*, D. Heidary *, E. Glazer * & D. Kim *
TL;DR:
It was concluded that both structural defects in sp2-carbon domains and oxygen-containing chemical groups have a crucial role in the excellent photodynamic performance.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2017 journal article
A high-throughput screening assay using a photoconvertable protein for identifying inhibitors of transcription, translation, or proteasomal degradation
SLAS Discovery, 22(4), 399–407.
Contributors: D. Heidary *, A. Fox*, C. Richards * & E. Glazer *
TL;DR:
The photoconvertable protein Dendra2 is used in the development of in-cell assays of protein production and degradation that are optimized and validated for high-throughput screening.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2017 journal article
Combining a Ru(II) “Building Block” and Rapid Screening Approach to Identify DNA Structure-Selective “Light Switch” Compounds
ACS Combinatorial Science, 19(2), 85–95.
Contributors: E. Wachter*, D. Moyá* & E. Glazer *
TL;DR:
A chemically reactive Ru(II) "building block", able to undergo condensation reactions with substituted diamines, was utilized to create a small library of luminescent "light switch" dipyrido-[3,2-a:2',3'-c] phenazine (dppz) complexes.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2017 journal article
Panchromatic Osmium Complexes for Photodynamic Therapy: Solutions to Existing Problems and New Questions
Photochemistry and Photobiology, 93(5), 1326–1328.
Contributors: E. Glazer *
TL;DR:
Findings in the study raise hopes for the development of novel photosensitizers that overcome the limitations of current commercially available systems for PDT, but also raise questions regarding the most efficacious biological mechanisms of action for this treatment modality.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2017 journal article
Photochemical Properties and Structure–Activity Relationships of Ru<sup>II</sup> Complexes with Pyridylbenzazole Ligands as Promising Anticancer Agents
European Journal of Inorganic Chemistry, 2017(12), 1687–1694.
Contributors: D. Havrylyuk* , D. Heidary *, L. Nease*, S. Parkin * & E. Glazer *
author keywords: Synthesis; Photochemistry; Cytotoxicity; DNA damage; Ruthenium
TL;DR:
The structure-activity relationship was focused on the benzazole core bioisosterism and replacement of coligands in Ru(II) complexes, which were non-toxic in the absence of light, induced cytotoxicity at nanomolar concentrations after light irradiation, and are capable of light-induced DNA damage.
(via Semantic Scholar)
Source: ORCID
Added: January 23, 2023
2017 journal article
Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands
Inorganic Chemistry, 56(20), 12214–12223.
Contributors: L. Kohler*, L. Nease*, P. Vo*, J. Garofolo*, D. Heidary *, R. Thummel *, E. Glazer *
TL;DR:
Light-activated compounds are powerful tools and potential agents for medical applications, as biological effects can be controlled in space and time and specific methylation patterns were associated with improved activation with red light, and photolabile complexes were generally more potent cytotoxic agents than the photostable 1O2-generating compounds.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2017 journal article
Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage
Dalton Transactions, 46(7), 2165–2173.
Contributors: A. Zamora*, C. Denning*, D. Heidary *, E. Wachter*, L. Nease*, J. Ruiz *, E. Glazer *
TL;DR:
Ruthenium complexes containing P450 inhibitors as ligands were synthesized in order to develop pro-drugs that can be triggered to release the inhibitors in a spatially and temporally controlled fashion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2016 journal article
An exceptional 5:4 enantiomeric structure
Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 72(2), 223–231.
Contributors: E. Wachter*, E. Glazer *, S. Parkin * & C. Brock *
TL;DR:
The ca 80:20 inversion twinning found indicates that enantiomeric preference is transmitted less perfectly across the anion/solvent layer than within the cation layer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2016 journal article
Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450<inf>BM3</inf> Variants
Biochemistry, 55(25), 3594–3606.
Contributors: I. Geronimo *, C. Denning*, W. Rogers *, T. Othman*, T. Huxford *, D. Heidary *, E. Glazer *, C. Payne *
TL;DR:
It is demonstrated that the heme domain R47L/F87V/L188Q/E267V/F81I pentuple mutant (PM) is destabilized because of the disruption of hydrophobic contacts and salt bridge interactions, and the lid domain, β-sheet 1, and Cys ligand loop are the most labile regions and, thus, potential sites for stabilizing mutations.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2016 journal article
Geometry matters: Inverse cytotoxic relationship for: Cis / trans -Ru(II) polypyridyl complexes from cis / trans -[PtCl<inf>2</inf>(NH<inf>3</inf>)<inf>2</inf>]
Chemical Communications, 52(66), 10121–10124.
Contributors: E. Wachter*, A. Zamora*, D. Heidary *, J. Ruiz * & E. Glazer *
TL;DR:
In contrast to the geometry requirements for cisplatin, trans-Ru(qpy)Cl2 was 7.1-9.5× more cytotoxic than cis-Ru (bpy)2Cl2, which could open up a new area of metal-based chemotherapeutic research.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2016 journal article
Light-sensitive ruthenium complex-loaded cross-linked polymeric nanoassemblies for the treatment of cancer
Journal of Materials Chemistry B, 4(3), 394–408.
Contributors: M. Dickerson *, B. Howerton*, Y. Bae * & E. C. Glazer *
TL;DR:
The cell cytotoxicity of CNA formulations was similar to free Ru complexes despite reduced or eliminated DNA interactions, and among other possibilities, accelerated release in a cell culture environment may be responsible.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2016 journal article
Ruthenium Complex "Light Switches" that are Selective for Different G-Quadruplex Structures
Chemistry - A European Journal, 22(2), 550–559.
Contributors: E. Wachter*, D. Moyá*, S. Parkin * & E. Glazer *
TL;DR:
These complexes demonstrate that subtle chemical modifications of Ru(II) complexes can alter G- quadruplex selectivity, and could be useful for the rational design of in vivo G-quadruplex probes.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2016 journal article
So-called "dual emission" for <sup>3</sup>MLCT luminescence in ruthenium complex ions: What is really happening?
Coordination Chemistry Reviews, 306, 447–467.
Contributors: D. Magde*, M. Magde* & E. Glazer *
TL;DR:
This mechanism accounts for the fact that highly asymmetric substitutions at the 4-position of the phen ligand that most affects charge transfer always show dual emission and offer the most exaggerated differences between the two emissions.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2014 journal article
A light-activated metal complex targets both DNA and RNA in a fluorescent in vitro transcription and translation assay
ChemBioChem, 15(4), 507–511.
Contributors: D. Heidary * & E. Glazer *
TL;DR:
A coupled in vitro transcription and translation (IVTT) assay that uses GFP as a fluorescent reporter allowed the potency of a light‐activated cytotoxic ruthenium agent to be quantified.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2014 journal article
A new type of DNA "light-switch": A dual photochemical sensor and metalating agent for duplex and G-quadruplex DNA
Chemical Communications, 50(3), 311–313.
Contributors: E. Wachter*, B. Howerton*, E. Hall*, S. Parkin * & E. Glazer *
TL;DR:
Ru(bpy)2dppz, a well studied "light-switch" metal complex, transforms into a photochemical " light- switch" and DNA damaging agent by incorporating structural strain.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2014 journal article
Coordination of hydroxyquinolines to a ruthenium bis-dimethyl-phenanthroline scaffold radically improves potency for potential as antineoplastic agents
Journal of Medicinal Chemistry, 57(21), 8936–8946.
Contributors: D. Heidary *, B. Howerton* & E. Glazer *
TL;DR:
A series of ruthenium coordination complexes containing hydroxyquinoline ligands were synthesized that exhibited radically improved potencies up to 86-fold greater than clioquinol, a known cytotoxic compound.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2014 journal article
Mechanistic study on the photochemical "light switch" behavior of [Ru(bpy)<inf>2</inf>dmdppz]<sup>2+</sup>
Journal of Physical Chemistry A, 118(45), 10474–10486.
Contributors: E. Wachter* & E. Glazer *
TL;DR:
Results from these studies indicate that the mechanism of substitution is associative or interchange associative, in contrast with the dissociative mechanism of other photolabile Ru(II) polypyridyl complexes.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2014 journal article
Modifying charge and hydrophilicity of simple Ru(II) polypyridyl complexes radically alters biological activities: Old complexes, surprising new tricks
Inorganic Chemistry, 53(19), 10370–10377.
Contributors: M. Dickerson *, Y. Sun *, B. Howerton* & E. Glazer *
TL;DR:
The incorporation of negative charged ligands provides a simple chemical approach to modify the biological properties of light-activated Ru(II) cytotoxic agents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2014 journal article
Photoactive Ru(II) complexes with dioxinophenanthroline ligands are potent cytotoxic agents
Inorganic Chemistry, 53(19), 10030–10032.
Contributors: A. Hidayatullah*, E. Wachter*, D. Heidary *, S. Parkin * & E. Glazer *
TL;DR:
The best compound exhibited a 1880-fold increase in cytotoxicity in human cancer cells upon light-activation and was 19-fold more potent than the well-known chemotherapeutic, cisplatin.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2013 journal article
Light-activated metal complexes that covalently modify DNA
Israel Journal of Chemistry, 53(6-7), 391–400.
Contributors: E. Glazer *
TL;DR:
This review highlights the advances that demonstrate the potential of light-activated metal complexes as therapeutics and research tools for biomedical applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2012 journal article
Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window
Chemical Communications, 48(77), 9649–9651.
Contributors: E. Wachter*, D. Heidary *, B. Howerton*, S. Parkin * & E. Glazer *
TL;DR:
Structural analysis shows that distortion facilitates the photochemistry, and gel shift and cytotoxicity studies prove the compounds act as anti-cancer photodynamic therapy (PDT) agents in the tissue penetrant region.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2012 journal article
Strained ruthenium complexes are potent light-activated anticancer agents
Journal of the American Chemical Society, 134(20), 8324–8327.
Contributors: B. Howerton*, D. Heidary * & E. Glazer *
TL;DR:
The use of intramolecular strain may be applied as a general paradigm to develop light-activated ruthenium complexes for PDT applications to display potencies superior to cisplatin against 3D tumor spheroids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2011 journal article
Three clusters of conformational states in P450cam reveal a multistep pathway for closing of the substrate access channel
Biochemistry, 50(5), 693–703.
Contributors: Y. Lee*, E. Glazer *, R. Wilson*, C. Stout* & D. Goodin*
TL;DR:
The observed clustering of protein conformations over a wide range of ligand variants suggests a multistep closure of the enzyme around the substrate that begins by conformational selection from an ensemble of open conformations and proceeds through a well-defined intermediate, P450cam-I, before full closure to the P 450cam-C state in the presence of small substrates.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2008 journal article
Probing inducible nitric oxide synthase with a pterin-ruthenium(II) sensitizer wire
Angewandte Chemie - International Edition, 47(5), 898–901.
Contributors: E. Glazer *, Y. Le Nguyen, H. Gray * & D. Goodin*
TL;DR:
The pterin has been shown to serve both structural and catalytic roles in the enzyme by affecting the monomer to dimer transition, promoting protein stability, and forming a radical cation during catalytic turnover.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2007 book
Conjugates of heme-thiolate enzymes with photoactive metal-diimine wires
In Structure and Bonding (Vol. 123, pp. 177–203).
Contributors: S. Contakes*, Y. Nguyen *, H. Gray *, E. Glazer *, A. Hays* & D. Goodin*
TL;DR:
Wires that feature a photoactive head group tethered to an active-site ligand bind P450CAM and induciblenitric oxide synthase (iNOS) primarily by hydrophobic interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2007 journal article
Ruthenium complexes that break the rules: Structural features controlling dual emission
Journal of the American Chemical Society, 129(27), 8544–8551.
Contributors: E. Glazer *, D. Magde* & Y. Tor *
TL;DR:
A family of heteroleptic RuII coordination complexes containing substituted 1,10-phenanthroline (phen) ligands with extended conjugation was found to exhibit two simultaneously emissive excited states at room temperature in fluid solution, demonstrating a breakdown of the standard nonradiative decay pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2006 journal article
Photodimerizable ditopic ligand
Organic Letters, 8(10), 1987–1990.
Contributors: D. Jouvenot *, E. Glazer * & Y. Tor *
TL;DR:
The synthesis, photophysical properties, and structural characterization of a photodimerizable ditopic ligand are described, which can be dissociated back to 1 using higher energy irradiation (254 nm).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2005 journal article
A simple synthesis of isotopically pure 2,2′-dipyridyl-d<inf>8</inf>
Inorganic Chemistry Communications, 8(6), 517–519.
Contributors: E. Glazer *, B. Belyea* & Y. Tor *
Source: ORCID
Added: November 30, 2023
2005 journal article
Dual emission from a family of conjugated dinuclear Ru<sup>II</sup> complexes
Journal of the American Chemical Society, 127(12), 4190–4192.
Contributors: E. Glazer *, D. Magde* & Y. Tor *
TL;DR:
Dual emission is observed from a family of simple acetylene-linked dinuclear RuII complexes, where two MLCT excited states coexist at room temperature and in fluid solution, attributed to a specific substitution pattern on the bridging ligand.
(via Semantic Scholar)
Source: ORCID
Added: November 30, 2023
2005 journal article
Redox couples of inducible nitric oxide synthase
Journal of the American Chemical Society, 127(32), 11212–11213.
Contributors: A. Udit*, W. Belliston-Bittner*, E. Glazer *, Y. Le Nguyen, J. Gillan*, M. Hill *, M. Marletta *, D. Goodin*, H. Gray *
TL;DR:
Digital simulation of the experimental data implicates water dissociation from the heme as a gating mechanism for ET in iNOS and Voltammetry at higher scan rates reveals that the FeIII/II cathodic peak can be resolved into two components, which are attributable to Fe III/II couples of five- and six-coordinate hemes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2004 journal article
Symmetrical dinuclear complexes with high DNA affinity based on Ru(dpq)<inf>2</inf>(phen)<sup>2+</sup>
Chemical Communications, 10(8), 1018–1019. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442536689&partnerID=MN8TOARS
Contributors: J. Aldrich-Wright, C. Brodie, E. Glazer, N. Luedtke, L. Elson-Schwab & Y. Tor
Source: ORCID
Added: November 30, 2023
2002 journal article
Eilatin Ru(II) complexes display anti-HIV activity and enantiomeric diversity in the binding of RNA
ChemBioChem, 3(8), 766–771.
Contributors: N. Luedtke *, J. Hwang*, E. Glazer *, D. Gut*, M. Kol * & Y. Tor *
TL;DR:
Eilatin‐containing octahedral ruthenium complexes inhibit HIV‐1 replication in CD4+ HeLa cells and in human peripheral blood monocytes with IC50 values of approximately 1 μM, which indicates that the extended planar surface presented by eilatin is important for both activities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 30, 2023
2002 journal article
Ru<sup>II</sup> complexes of "large-surface" ligands
Angewandte Chemie - International Edition, 41(21), 4022–4026.
Contributors: E. Glazer * & Y. Tor *
Source: ORCID
Added: November 30, 2023
2000 journal article
High speed PVK-based photorefractive polymer composites
Molecular Crystals and Liquid Crystals Science and Technology Section B: Nonlinear Optics, 25(1-4), 189–194. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034454642&partnerID=MN8TOARS
Contributors: M. Díaz-García, D. Wright, J. Casperson, B. Smith, E. Glazer, W. Moerner, L. Sukhomlinova, R. Twieg
Source: ORCID
Added: November 30, 2023
1999 conference paper
Chiral metal-containing polymers
American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 40(1), 513–514. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033089595&partnerID=MN8TOARS
Contributors: E. Glazer & Y. Tor
Source: ORCID
Added: November 30, 2023
1999 journal article
Photorefractive properties of poly(N-vinyl carbazole)-based composites for high-speed applications
Chemistry of Materials, 11(7), 1784–1791. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001188375&partnerID=MN8TOARS
Contributors: M. Díaz-García, D. Wright, J. Casperson, B. Smith, E. Glazer, W. Moerner, L. Sukhomlinova, R. Twieg
Source: ORCID
Added: November 30, 2023
1999 conference paper
Understanding trapping in photorefractive polymer composites for optical processing applications
IQEC, International Quantum Electronics Conference Proceedings, 186–187. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032645912&partnerID=MN8TOARS
Contributors: W. Moerner, A. Grunnet-Jepsen, D. Wright, J. Casperson, E. Glazer, M. DeClue, J. Siegel, R. Twieg
Source: ORCID
Added: November 30, 2023
Employment
Updated: February 17th, 2023 13:18
2023 - present
North Carolina State University Raleigh, North Carolina, US
Professor
Chemistry
Education
Updated: September 14th, 2021 12:07
University of California, San Diego San Diego, California, US
PhD
Chemistry and Biochemistry
Williams College Williamstown, MA, US
BA
Chemistry
Funding History
Funding history based on the linked ORCID record. Updated: September 14th, 2021 12:05
grant
September 1, 2020 - June 30, 2024
Role of small molecule interactions and multiprotein assemblies in CYP1B1 disease-associated function and dysfunction
National Institute of General Medical Sciences
grant
August 15, 2020 - July 31, 2023
Inorganic-aptamer hybrids for live cell imaging
Directorate for Mathematical & Physical Sciences
grant
March 24, 2018 - March 23, 2019
2018 Metals in Medicine Gordon Research Conference
National Center for Advancing Translational Sciences
grant
August 15, 2016 - July 31, 2019
MRI: Acquisition of a Single-Crystal Diffractometer for Chemistry and Materials Research
Directorate for Mathematical & Physical Sciences
grant
August 1, 2014 - July 31, 2020
Light-responsive ruthenium compounds for applications in disease
National Institute of General Medical Sciences
grant
January 1, 2006 - June 30, 2007
Ru(II)-Containing Wires for ET Studies in Metalloenzymes
National Institute of General Medical Sciences
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