Phoebe Glazer

The Impact of Inorganic Systems and Photoactive Metal Compounds on Cytochrome P450 Enzymes and Metabolism: From Induction to Inhibition

Havrylyuk, D., Heidary, D. K., & Glazer, E. C. (2024, April 4). Biomolecules, Vol. 14.

Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity

Photochemistry and Photobiology, 98(1), 73–84.

Avobenzone incorporation in a diverse range of Ru(ii) scaffolds produces potent potential antineoplastic agents

Dalton Transactions, 49(35), 12161–12167.

Bis-tridentate N-Heterocyclic Carbene Ru(II) Complexes are Promising New Agents for Photodynamic Therapy

Ryan, R. T., Stevens, K. C., Calabro, R., Parkin, S., Mahmoud, J., Kim, D. Y., … Selegue, J. P. (2020, June 12). Inorganic Chemistry.

Bacterial Cytological Profiling Reveals the Mechanism of Action of Anticancer Metal Complexes

Sun, Y., Heidary, D. K., Zhang, Z., Richards, C. I., & Glazer, E. C. (2018, June 4). Molecular Pharmaceutics, Vol. 15, pp. 3404–3416.

Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450BM3 Variant

Geronimo, I., Denning, C. A., Heidary, D. K., Glazer, E. C., & Payne, C. M. (2018, August 27). Biophysical Journal, Vol. 115, pp. 1251–1263.

Ru(ii) complexes with diazine ligands: electronic modulation of the coordinating group is key to the design of “dual action” photoactivated agents

Havrylyuk, D., Deshpande, M., Parkin, S., & Glazer, E. C. (2018, January 1). Chemical Communications, Vol. 54, pp. 12487–12490.

Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines

European Journal of Medicinal Chemistry, 156, 790–799.

Superior photodynamic effect of carbon quantum dots through both type I and type II pathways: Detailed comparison study of top-down-synthesized and bottom-up-synthesized carbon quantum dots

Pillar-Little, T. J., Wanninayake, N., Nease, L., Heidary, D. K., Glazer, E. C., & Kim, D. Y. (2018, September 1). Carbon, Vol. 140, pp. 616–623.

A High-Throughput Screening Assay Using a Photoconvertable Protein for Identifying Inhibitors of Transcription, Translation, or Proteasomal Degradation

Heidary, D. K., Fox, A., Richards, C. I., & Glazer, E. C. (2017, January 7). SLAS DISCOVERY, Vol. 22, pp. 399–407.

Panchromatic Osmium Complexes for Photodynamic Therapy: Solutions to Existing Problems and New Questions

Glazer, E. C. (2017, May 24). Photochemistry and Photobiology, Vol. 93, pp. 1326–1328.

Photochemical Properties and Structure–Activity Relationships of Ru^II Complexes with Pyridylbenzazole Ligands as Promising Anticancer Agents

Havrylyuk, D., Heidary, D. K., Nease, L., Parkin, S., & Glazer, E. C. (2017, January 30). European Journal of Inorganic Chemistry, Vol. 2017, pp. 1687–1694.

Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands

Kohler, L., Nease, L., Vo, P., Garofolo, J., Heidary, D. K., Thummel, R. P., & Glazer, E. C. (2017, September 26). Inorganic Chemistry, Vol. 56, pp. 12214–12223.

Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage

Zamora, A., Denning, C. A., Heidary, D. K., Wachter, E., Nease, L. A., Ruiz, J., & Glazer, E. C. (2017, January 1). Dalton Transactions, Vol. 46, pp. 2165–2173.

An exceptional 5:4 enantiomeric structure

Wachter, E., Glazer, E. C., Parkin, S., & Brock, C. P. (2016, April 1). Acta Crystallographica Section B Structural Science Crystal Engineering and Materials, Vol. 72, pp. 223–231.

Combining a Ru(II) “Building Block” and Rapid Screening Approach to Identify DNA Structure-Selective “Light Switch” Compounds

Wachter, E., Moyá, D., & Glazer, E. C. (2016, November 28). ACS Combinatorial Science, Vol. 19, pp. 85–95.

Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450_BM3 Variants

Geronimo, I., Denning, C. A., Rogers, W. E., Othman, T., Huxford, T., Heidary, D. K., … Payne, C. M. (2016, June 6). Biochemistry, Vol. 55, pp. 3594–3606.

Geometry matters: inverse cytotoxic relationship for cis/trans-Ru(ii) polypyridyl complexes from cis/trans-[PtCl₂(NH₃)₂]

Wachter, E., Zamora, A., Heidary, D. K., Ruiz, J., & Glazer, E. C. (2016, January 1). Chemical Communications, Vol. 52, pp. 10121–10124.

Light-sensitive ruthenium complex-loaded cross-linked polymeric nanoassemblies for the treatment of cancer

Dickerson, M., Howerton, B., Bae, Y., & Glazer, E. C. (2015, December 1). Journal of Materials Chemistry B, Vol. 4, pp. 394–408.

Ruthenium Complex “Light Switches” that are Selective for Different G‐Quadruplex Structures

Wachter, E., Moyá, D., Parkin, S., & Glazer, E. C. (2015, November 12). Chemistry - A European Journal, Vol. 22, pp. 550–559.

So-called “dual emission” for 3MLCT luminescence in ruthenium complex ions: What is really happening?

Magde, D., Magde, M. D., & Glazer, E. C. (2015, January 19). Coordination Chemistry Reviews, Vol. 306, pp. 447–467.

A Light‐Activated Metal Complex Targets both DNA and RNA in a Fluorescent in Vitro Transcription and Translation Assay

Heidary, D. K., & Glazer, E. C. (2014, January 31). ChemBioChem, Vol. 15, pp. 507–511.

Coordination of Hydroxyquinolines to a Ruthenium Bis-dimethyl-phenanthroline Scaffold Radically Improves Potency for Potential as Antineoplastic Agents

Heidary, D. K., Howerton, B. S., & Glazer, E. C. (2014, October 14). Journal of Medicinal Chemistry, Vol. 57, pp. 8936–8946.

Mechanistic Study on the Photochemical “Light Switch” Behavior of [Ru(bpy)₂dmdppz]²⁺

Wachter, E., & Glazer, E. C. (2014, July 15). The Journal of Physical Chemistry A, Vol. 118, pp. 10474–10486.

Modifying Charge and Hydrophilicity of Simple Ru(II) Polypyridyl Complexes Radically Alters Biological Activities: Old Complexes, Surprising New Tricks

Dickerson, M., Sun, Y., Howerton, B., & Glazer, E. C. (2014, September 24). Inorganic Chemistry, Vol. 53, pp. 10370–10377.

Photoactive Ru(II) Complexes With Dioxinophenanthroline Ligands Are Potent Cytotoxic Agents

Hidayatullah, A. N., Wachter, E., Heidary, D. K., Parkin, S., & Glazer, E. C. (2014, September 8). Inorganic Chemistry, Vol. 53, pp. 10030–10032.

A new type of DNA “light-switch”: a dual photochemical sensor and metalating agent for duplex and G-quadruplex DNA

Wachter, E., Howerton, B. S., Hall, E. C., Parkin, S., & Glazer, E. C. (2013, November 5). Chemical Communications, Vol. 50, pp. 311–313.

Light‐Activated Metal Complexes that Covalently Modify DNA

Glazer, E. C. (2013, June 1). Israel Journal of Chemistry, Vol. 53, pp. 391–400.

Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window

Wachter, E., Heidary, D. K., Howerton, B. S., Parkin, S., & Glazer, E. C. (2012, January 1). Chemical Communications, Vol. 48, pp. 9649–9651.

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

Howerton, B. S., Heidary, D. K., & Glazer, E. C. (2012, May 3). Journal of the American Chemical Society, Vol. 134, pp. 8324–8327.

Three Clusters of Conformational States in P450cam Reveal a Multistep Pathway for Closing of the Substrate Access Channel,

Lee, Y.-T., Glazer, E. C., Wilson, R. F., Stout, C. D., & Goodin, D. B. (2010, December 20). Biochemistry, Vol. 50, pp. 693–703.

Probing Inducible Nitric Oxide Synthase with a Pterin–Ruthenium(II) Sensitizer Wire

Glazer, E. C., Nguyen, Y. H. L., Gray, H. B., & Goodin, D. B. (2007, December 17). Angewandte Chemie International Edition, Vol. 47, pp. 898–901.

Ruthenium Complexes That Break the Rules:  Structural Features Controlling Dual Emission

Glazer, E. C., Magde, D., & Tor, Y. (2007, June 16). Journal of the American Chemical Society, Vol. 129, pp. 8544–8551.

Conjugates of Heme-Thiolate Enzymes with Photoactive Metal-Diimine Wires

Contakes, S. M., Nguyen, Y. H. L., Gray, H. B., Glazer, E. C., Hays, A.-M., & Goodin, D. B. (2006, January 1). Structure and Bonding, Vol. 123, pp. 177–203.

Photodimerizable Ditopic Ligand

Jouvenot, D., Glazer, E. C., & Tor, Y. (2006, April 21). Organic Letters, Vol. 8, pp. 1987–1990.

A simple synthesis of isotopically pure 2,2′-dipyridyl-d8

Glazer, E. C., Belyea, B., & Tor, Y. (2005, April 20). Inorganic Chemistry Communications, Vol. 8, pp. 517–519.

Dual Emission from a Family of Conjugated Dinuclear Ru^II Complexes

Glazer, E. C., Magde, D., & Tor, Y. (2005, March 1). Journal of the American Chemical Society, Vol. 127, pp. 4190–4192.

Redox Couples of Inducible Nitric Oxide Synthase

Udit, A. K., Belliston-Bittner, W., Glazer, E. C., Nguyen, Y. H. L., Gillan, J. M., Hill, M. G., … Gray, H. B. (2005, July 20). Journal of the American Chemical Society, Vol. 127, pp. 11212–11213.

Symmetrical dinuclear complexes with high DNA affinity based on Ru(dpq)2(phen)²⁺

Chemical Communications, 10(8), 1018–1019. http://www.scopus.com/inward/record.url?eid=2-s2.0-2442536689&partnerID=MN8TOARS

Eilatin Ru(II) Complexes Display Anti-HIV Activity and Enantiomeric Diversity in the Binding of RNA

Luedtke, N. W., Hwang, J. S., Glazer, E. C., Gut, D., Kol, M., & Tor, Y. (2002, August 2). ChemBioChem, Vol. 3, pp. 766–771.

RuII Complexes of “Large-Surface” Ligands

Glazer, E. C., & Tor, Y. (2002, October 31). Angewandte Chemie International Edition, Vol. 41, pp. 4022–4026.

High speed PVK-based photorefractive polymer composites

Molecular Crystals and Liquid Crystals Science and Technology Section B: Nonlinear Optics, 25(1-4), 189–194. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034454642&partnerID=MN8TOARS

Chiral metal-containing polymers

American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 40(1), 513–514. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033089595&partnerID=MN8TOARS

Photorefractive properties of poly(N-vinyl carbazole)-based composites for high-speed applications

Chemistry of Materials, 11(7), 1784–1791. http://www.scopus.com/inward/record.url?eid=2-s2.0-0001188375&partnerID=MN8TOARS

Understanding trapping in photorefractive polymer composites for optical processing applications

IQEC, International Quantum Electronics Conference Proceedings, 186–187. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032645912&partnerID=MN8TOARS