Phoebe Glazer

Havrylyuk, D., Heidary, D. K., & Glazer, E. (2024). The Impact of Inorganic Systems and Photoactive Metal Compounds on Cytochrome P450 Enzymes and Metabolism: From Induction to Inhibition. Biomolecules. https://doi.org/10.3390/biom14040441

Cole, H. D., Roque, J. A., III, Lifshits, L. M., Hodges, R., Barrett, P. C., Havrylyuk, D., … McFarland, S. A. (2021). Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity. Photochemistry and Photobiology, 98(1), 73–84. https://doi.org/10.1111/php.13395

Ryan, R. T., Havrylyuk, D., Stevens, K. C., Moore, L. H., Kim, D. Y., Blackburn, J. S., … Glazer, E. C. (2020). Avobenzone incorporation in a diverse range of Ru(<scp>ii</scp>) scaffolds produces potent potential antineoplastic agents. Dalton Transactions, 49(35), 12161–12167. https://doi.org/10.1039/d0dt02016h

Bis-tridentate N-Heterocyclic Carbene Ru(II) Complexes are Promising New Agents for Photodynamic Therapy. (2020). Inorganic Chemistry. https://doi.org/10.1021/acs.inorgchem.0c00686

Sun, Y., Heidary, D. K., Zhang, Z., Richards, C. I., & Glazer, E. C. (2018). Bacterial Cytological Profiling Reveals the Mechanism of Action of Anticancer Metal Complexes. Molecular Pharmaceutics, 15(8), 3404–3416. https://doi.org/10.1021/acs.molpharmaceut.8b00407

Geronimo, I., Denning, C. A., Heidary, D. K., Glazer, E. C., & Payne, C. M. (2018). Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450<inf>BM3</inf> Variant. Biophysical Journal, 115(7), 1251–1263. https://doi.org/10.1016/j.bpj.2018.08.026

Havrylyuk, D., Deshpande, M., Parkin, S., & Glazer, E. C. (2018). Ru(ii) complexes with diazine ligands: Electronic modulation of the coordinating group is key to the design of "dual action" photoactivated agents. Chemical Communications, 54(88), 12487–12490. https://doi.org/10.1039/c8cc05809a

Havrylyuk, D., Howerton, B. S., Nease, L., Parkin, S., Heidary, D. K., & Glazer, E. C. (2018). Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines. European Journal of Medicinal Chemistry, 156, 790–799. https://doi.org/10.1016/j.ejmech.2018.04.044

Pillar-Little, T. J., Wanninayake, N., Nease, L., Heidary, D. K., Glazer, E. C., & Kim, D. Y. (2018). Superior photodynamic effect of carbon quantum dots through both type I and type II pathways: Detailed comparison study of top-down-synthesized and bottom-up-synthesized carbon quantum dots. Carbon, 140, 616–623. https://doi.org/10.1016/j.carbon.2018.09.004

Heidary, D. K., Fox, A., Richards, C. I., & Glazer, E. C. (2017). A high-throughput screening assay using a photoconvertable protein for identifying inhibitors of transcription, translation, or proteasomal degradation. SLAS Discovery, 22(4), 399–407. https://doi.org/10.1177/2472555216684333

Wachter, E., Moyá, D., & Glazer, E. C. (2017). Combining a Ru(II) “Building Block” and Rapid Screening Approach to Identify DNA Structure-Selective “Light Switch” Compounds. ACS Combinatorial Science, 19(2), 85–95. https://doi.org/10.1021/acscombsci.6b00119

Glazer, E. C. (2017). Panchromatic Osmium Complexes for Photodynamic Therapy: Solutions to Existing Problems and New Questions. Photochemistry and Photobiology, 93(5), 1326–1328. https://doi.org/10.1111/php.12796

Havrylyuk, D., Heidary, D. K., Nease, L., Parkin, S., & Glazer, E. C. (2017). Photochemical Properties and Structure–Activity Relationships of Ru<sup>II</sup> Complexes with Pyridylbenzazole Ligands as Promising Anticancer Agents. European Journal of Inorganic Chemistry, 2017(12), 1687–1694. https://doi.org/10.1002/ejic.201601450

Kohler, L., Nease, L., Vo, P., Garofolo, J., Heidary, D. K., Thummel, R. P., & Glazer, E. C. (2017). Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands. Inorganic Chemistry, 56(20), 12214–12223. https://doi.org/10.1021/acs.inorgchem.7b01642

Zamora, A., Denning, C. A., Heidary, D. K., Wachter, E., Nease, L. A., Ruiz, J., & Glazer, E. C. (2017). Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage. Dalton Transactions, 46(7), 2165–2173. https://doi.org/10.1039/C6DT04405K

Wachter, E., Glazer, E. C., Parkin, S., & Brock, C. P. (2016). An exceptional 5:4 enantiomeric structure. Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 72(2), 223–231. https://doi.org/10.1107/S205252061600127X

Geronimo, I., Denning, C. A., Rogers, W. E., Othman, T., Huxford, T., Heidary, D. K., … Payne, C. M. (2016). Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450<inf>BM3</inf> Variants. Biochemistry, 55(25), 3594–3606. https://doi.org/10.1021/acs.biochem.6b00183

Wachter, E., Zamora, A., Heidary, D. K., Ruiz, J., & Glazer, E. C. (2016). Geometry matters: Inverse cytotoxic relationship for: Cis / trans -Ru(II) polypyridyl complexes from cis / trans -[PtCl<inf>2</inf>(NH<inf>3</inf>)<inf>2</inf>]. Chemical Communications, 52(66), 10121–10124. https://doi.org/10.1039/c6cc04813g

Dickerson, M., Howerton, B., Bae, Y., & C. Glazer, E. (2016). Light-sensitive ruthenium complex-loaded cross-linked polymeric nanoassemblies for the treatment of cancer. Journal of Materials Chemistry B, 4(3), 394–408. https://doi.org/10.1039/c5tb01613d

Wachter, E., Moyá, D., Parkin, S., & Glazer, E. C. (2016). Ruthenium Complex "Light Switches" that are Selective for Different G-Quadruplex Structures. Chemistry - A European Journal, 22(2), 550–559. https://doi.org/10.1002/chem.201503203

Magde, D., Magde, M. D., & Glazer, E. C. (2016). So-called "dual emission" for <sup>3</sup>MLCT luminescence in ruthenium complex ions: What is really happening? Coordination Chemistry Reviews, 306, 447–467. https://doi.org/10.1016/j.ccr.2015.01.003

Heidary, D. K., & Glazer, E. C. (2014). A light-activated metal complex targets both DNA and RNA in a fluorescent in vitro transcription and translation assay. ChemBioChem, 15(4), 507–511. https://doi.org/10.1002/cbic.201300681

Wachter, E., Howerton, B. S., Hall, E. C., Parkin, S., & Glazer, E. C. (2014). A new type of DNA "light-switch": A dual photochemical sensor and metalating agent for duplex and G-quadruplex DNA. Chemical Communications, 50(3), 311–313. https://doi.org/10.1039/c3cc47269h

Heidary, D. K., Howerton, B. S., & Glazer, E. C. (2014). Coordination of hydroxyquinolines to a ruthenium bis-dimethyl-phenanthroline scaffold radically improves potency for potential as antineoplastic agents. Journal of Medicinal Chemistry, 57(21), 8936–8946. https://doi.org/10.1021/jm501043s

Wachter, E., & Glazer, E. C. (2014). Mechanistic study on the photochemical "light switch" behavior of [Ru(bpy)<inf>2</inf>dmdppz]<sup>2+</sup>. Journal of Physical Chemistry A, 118(45), 10474–10486. https://doi.org/10.1021/jp504249a

Dickerson, M., Sun, Y., Howerton, B., & Glazer, E. C. (2014). Modifying charge and hydrophilicity of simple Ru(II) polypyridyl complexes radically alters biological activities: Old complexes, surprising new tricks. Inorganic Chemistry, 53(19), 10370–10377. https://doi.org/10.1021/ic5013796

Hidayatullah, A. N., Wachter, E., Heidary, D. K., Parkin, S., & Glazer, E. C. (2014). Photoactive Ru(II) complexes with dioxinophenanthroline ligands are potent cytotoxic agents. Inorganic Chemistry, 53(19), 10030–10032. https://doi.org/10.1021/ic5017164

Glazer, E. C. (2013). Light-activated metal complexes that covalently modify DNA. Israel Journal of Chemistry, 53(6-7), 391–400. https://doi.org/10.1002/ijch.201300019

Wachter, E., Heidary, D. K., Howerton, B. S., Parkin, S., & Glazer, E. C. (2012). Light-activated ruthenium complexes photobind DNA and are cytotoxic in the photodynamic therapy window. Chemical Communications, 48(77), 9649–9651. https://doi.org/10.1039/c2cc33359g

Howerton, B. S., Heidary, D. K., & Glazer, E. C. (2012). Strained ruthenium complexes are potent light-activated anticancer agents. Journal of the American Chemical Society, 134(20), 8324–8327. https://doi.org/10.1021/ja3009677

Lee, Y.-T., Glazer, E. C., Wilson, R. F., Stout, C. D., & Goodin, D. B. (2011). Three clusters of conformational states in P450cam reveal a multistep pathway for closing of the substrate access channel. Biochemistry, 50(5), 693–703. https://doi.org/10.1021/bi101726d

Glazer, E. C., Le Nguyen, Y. H., Gray, H. B., & Goodin, D. B. (2008). Probing inducible nitric oxide synthase with a pterin-ruthenium(II) sensitizer wire. Angewandte Chemie - International Edition, 47(5), 898–901. https://doi.org/10.1002/anie.200703743

Contakes, S. M., Nguyen, Y. H. L., Gray, H. B., Glazer, E. C., Hays, A.-M., & Goodin, D. B. (2007). Conjugates of heme-thiolate enzymes with photoactive metal-diimine wires. In Structure and Bonding (Vol. 123, pp. 177–203). https://doi.org/10.1007/430_2006_039

Glazer, E. C., Magde, D., & Tor, Y. (2007). Ruthenium complexes that break the rules: Structural features controlling dual emission. Journal of the American Chemical Society, 129(27), 8544–8551. https://doi.org/10.1021/ja071124f

Jouvenot, D., Glazer, E. C., & Tor, Y. (2006). Photodimerizable ditopic ligand. Organic Letters, 8(10), 1987–1990. https://doi.org/10.1021/ol060253i

Glazer, E. C., Belyea, B., & Tor, Y. (2005). A simple synthesis of isotopically pure 2,2′-dipyridyl-d<inf>8</inf>. Inorganic Chemistry Communications, 8(6), 517–519. https://doi.org/10.1016/j.inoche.2005.03.011

Glazer, E. C., Magde, D., & Tor, Y. (2005). Dual emission from a family of conjugated dinuclear Ru<sup>II</sup> complexes. Journal of the American Chemical Society, 127(12), 4190–4192. https://doi.org/10.1021/ja0440304

Udit, A. K., Belliston-Bittner, W., Glazer, E. C., Le Nguyen, Y. H., Gillan, J. M., Hill, M. G., … Gray, H. B. (2005). Redox couples of inducible nitric oxide synthase. Journal of the American Chemical Society, 127(32), 11212–11213. https://doi.org/10.1021/ja0520114

Aldrich-Wright, J., Brodie, C., Glazer, E. C., Luedtke, N. W., Elson-Schwab, L., & Tor, Y. (2004). Symmetrical dinuclear complexes with high DNA affinity based on Ru(dpq)<inf>2</inf>(phen)<sup>2+</sup>. Chemical Communications, 10(8), 1018–1019. Retrieved from http://www.scopus.com/inward/record.url?eid=2-s2.0-2442536689&partnerID=MN8TOARS

Luedtke, N. W., Hwang, J. S., Glazer, E. C., Gut, D., Kol, M., & Tor, Y. (2002). Eilatin Ru(II) complexes display anti-HIV activity and enantiomeric diversity in the binding of RNA. ChemBioChem, 3(8), 766–771. https://doi.org/10.1002/1439-7633(20020802)3:8<766::AID-CBIC766>3.0.CO;2-X

Glazer, E. C., & Tor, Y. (2002). Ru<sup>II</sup> complexes of "large-surface" ligands. Angewandte Chemie - International Edition, 41(21), 4022–4026. https://doi.org/10.1002/1521-3773(20021104)41:21<4022::AID-ANIE4022>3.0.CO;2-1

Díaz-García, M. A., Wright, D., Casperson, J. D., Smith, B., Glazer, E., Moerner, W. E., … Twieg, R. J. (2000). High speed PVK-based photorefractive polymer composites. Molecular Crystals and Liquid Crystals Science and Technology Section B: Nonlinear Optics, 25(1-4), 189–194. Retrieved from http://www.scopus.com/inward/record.url?eid=2-s2.0-0034454642&partnerID=MN8TOARS

Glazer, E. C., & Tor, Y. (1999). Chiral metal-containing polymers. American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 40(1), 513–514. Retrieved from http://www.scopus.com/inward/record.url?eid=2-s2.0-0033089595&partnerID=MN8TOARS

Díaz-García, M. A., Wright, D., Casperson, J. D., Smith, B., Glazer, E., Moerner, W. E., … Twieg, R. J. (1999). Photorefractive properties of poly(N-vinyl carbazole)-based composites for high-speed applications. Chemistry of Materials, 11(7), 1784–1791. Retrieved from http://www.scopus.com/inward/record.url?eid=2-s2.0-0001188375&partnerID=MN8TOARS

Moerner, W. E., Grunnet-Jepsen, A., Wright, D., Casperson, J., Glazer, E., DeClue, M., … Twieg, R. J. (1999). Understanding trapping in photorefractive polymer composites for optical processing applications. IQEC, International Quantum Electronics Conference Proceedings, 186–187. Retrieved from http://www.scopus.com/inward/record.url?eid=2-s2.0-0032645912&partnerID=MN8TOARS