Elizabeth S. Hecht

Works (8)

Updated: July 6th, 2023 21:17
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2019 journal article

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods

Molecular & Cellular Proteomics, 19(1), 11–30.

By: M. De Leoz *, D. Duewer *, A. Fung, L. Liu, H. Yau, O. Potter*, G. Staples *, K. Furuki* ...

author keywords: Glycomics; mass spectrometry; fluorescence; glycosylation; glycoproteins; glycan; glycopeptide; interlaboratory study; NISTmAb; reference antibody
MeSH headings : Antibodies, Monoclonal / chemistry; Antibodies, Monoclonal / metabolism; Biological Products; Biopharmaceutics / methods; Glycomics / methods; Glycopeptides / metabolism; Glycosylation; Humans; Laboratories; Polysaccharides / metabolism; Protein Processing, Post-Translational; Proteomics / methods
Sources: Crossref, ORCID
Added: May 11, 2020

2017 journal article

DRILL: An Electrospray Ionization-Mass Spectrometry Interface for Improved Sensitivity via Inertial Droplet Sorting and Electrohydrodynamic Focusing in a Swirling Flow

ANALYTICAL CHEMISTRY, 89(17), 8981–8987.

By: P. Kottke *, J. Lee *, A. Jonke*, C. Seneviratne  n, E. Hecht n, D. Muddiman n , M. Torres *, A. Fedorov *

MeSH headings : Angiotensin I / analysis; Angiotensin I / metabolism; Angiotensin II / analysis; Angiotensin II / metabolism; Chromatography, High Pressure Liquid; Humans; Isotope Labeling; Limit of Detection; Peptides / analysis; Peptides / chemistry; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

N-linked glycosite profiling and use of Skyline as a platform for characterization and relative quantification of glycans in differentiating xylem of Populus trichocarpa

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409(2), 487–497.

By: P. Loziuk n, E. Hecht n & D. Muddiman n 

author keywords: N-linked glycosite; Skyline; Populus trichocarpa; Monolignol; N-linked glycans
MeSH headings : Computational Biology / standards; Computational Biology / trends; Polysaccharides / analysis; Populus / chemistry; Xylem / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Xylose Migration During Tandem Mass Spectrometry of N-Linked Glycans

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 28(4), 729–732.

By: E. Hecht n, P. Loziuk n & D. Muddiman n 

author keywords: Xylose migration; MS/MS; Glycomics; N-linked glycans; Plants
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

A quantitative glycomics and proteomics combined purification strategy

Jove-Journal of Visualized Experiments, (109).

By: E. Hecht, J. McCord & D. Muddiman 

Source: NC State University Libraries
Added: August 6, 2018

2016 review

Optimizing Mass Spectrometry Analyses: A Tailored Review on the Utility of Design of Experiments

[Review of ]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 27(5), 767–785.

By: E. Hecht n, A. Oberg * & D. Muddiman n 

author keywords: Design of experiments; Mass spectrometry; Tutorial; Optimization; Modeling
MeSH headings : Mass Spectrometry; Models, Statistical; Research Design
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Definitive Screening Design Optimization of Mass Spectrometry Parameters for Sensitive Comparison of Filter and Solid Phase Extraction Purified, INLIGHT Plasma N-Glycans

ANALYTICAL CHEMISTRY, 87(14), 7305–7312.

By: E. Hecht n, J. McCord n & D. Muddiman n 

MeSH headings : Animals; Chickens; Equipment Design; Mass Spectrometry / instrumentation; Polysaccharides / blood; Polysaccharides / isolation & purification; Solid Phase Extraction / instrumentation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Relative Quantification and Higher-Order Modeling of the Plasma Glycan Cancer Burden Ratio in Ovarian Cancer Case-Control Samples

JOURNAL OF PROTEOME RESEARCH, 14(10), 4394–4401.

By: E. Hecht*, E. Scholl*, S. Walker*, A. Taylor, W. Cliby *, A. Motsinger-Reif*, D. Muddiman* 

author keywords: N-linked glycosylation; INLIGHT; ovarian cancer; relative quantification; cancer biomarker; human plasma
MeSH headings : Biomarkers, Tumor / blood; Carbohydrate Sequence; Case-Control Studies; Chromatography, Liquid / methods; Female; Fucose / blood; Glycosylation; Humans; Hydrazines / chemistry; Molecular Sequence Data; Neoplasm Staging; Ovarian Neoplasms / blood; Ovarian Neoplasms / diagnosis; Ovarian Neoplasms / pathology; Polysaccharides / blood; Sialic Acids / blood; Staining and Labeling / methods; Tandem Mass Spectrometry / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018