Beth Overman

Works (3)

Updated: July 5th, 2023 15:45

2013 article

Early Weaning Stress in Pigs Impairs Innate Mucosal Immune Responses to Enterotoxigenic E. coli Challenge and Exacerbates Intestinal Injury and Clinical Disease

McLamb, B. L., Gibson, A. J., Overman, E. L., Stahl, C., & Moeser, A. J. (2013, April 24). PLoS ONE.

By: B. McLamb n, A. Gibson n, E. Overman n, C. Stahl  n & A. Moeser n

MeSH headings : Animals; Animals, Newborn; Cytokines / immunology; Cytokines / metabolism; Dextrans / metabolism; Enterotoxigenic Escherichia coli / immunology; Enterotoxigenic Escherichia coli / pathogenicity; Escherichia coli Infections / veterinary; Ileum / immunology; Ileum / metabolism; Ileum / microbiology; Ileum / pathology; Immunity, Innate; Immunity, Mucosal; Inflammation Mediators / immunology; Inflammation Mediators / metabolism; Intestinal Mucosa / immunology; Intestinal Mucosa / microbiology; Intestinal Mucosa / pathology; Mast Cells / immunology; Mast Cells / pathology; Neutrophils / immunology; Neutrophils / pathology; Permeability; Stress, Physiological / immunology; Swine; Swine Diseases / immunology; Weaning
topics (OpenAlex): Gut microbiota and health; Viral gastroenteritis research and epidemiology; Stress Responses and Cortisol
TL;DR: The early weaning stress can profoundly alter subsequent immune and physiology responses and clinical outcomes to subsequent infectious pathogen challenge, as demonstrated in pigs weaned from their dam. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 article

Infection with feline immunodeficiency virus alters intestinal epithelial transport and mucosal immune responses to probiotics

Stoeker, L. L., Overman, E. L., Nordone, S. K., Moeser, A. J., Simões, R. D., & Dean, G. A. (2013, February 8). Veterinary Immunology and Immunopathology.

By: L. Stoeker n, E. Overman n, S. Nordone n, A. Moeser n, R. Simões n & G. Dean *

author keywords: HIV; FIV; Lactobacillus; Mucosal immune system
MeSH headings : Animals; Biological Transport; Cats; Electric Impedance; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / metabolism; Immunity, Mucosal / drug effects; Intestinal Mucosa / metabolism; Probiotics / pharmacology
topics (OpenAlex): HIV Research and Treatment; Gut microbiota and health; HIV/AIDS oral health manifestations
TL;DR: A novel role for FIV in upregulating transcellular transport across the gastrointestinal epithelial barrier is suggested and the potential therapeutic use of probiotic bacteria to restore intestinal homeostasis is demonstrated. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 article

CRF Induces Intestinal Epithelial Barrier Injury via the Release of Mast Cell Proteases and TNF-α

Overman, E. L., Rivier, J. E., & Moeser, A. J. (2012, June 29). PLoS ONE.

By: E. Overman n, J. Rivier* & A. Moeser n

MeSH headings : Animals; Cell Degranulation / drug effects; Corticotropin-Releasing Hormone / pharmacology; Dextrans; Enteric Nervous System / drug effects; Enteric Nervous System / pathology; Fluorescein-5-isothiocyanate / analogs & derivatives; Ileum / drug effects; Ileum / pathology; Ileum / physiopathology; In Vitro Techniques; Intestinal Mucosa / drug effects; Intestinal Mucosa / injuries; Intestinal Mucosa / pathology; Intestinal Mucosa / physiopathology; Mast Cells / drug effects; Mast Cells / enzymology; Mast Cells / physiology; Molecular Weight; Neutralization Tests; Occludin / metabolism; Peptide Fragments / pharmacology; Peptide Hydrolases / metabolism; Permeability / drug effects; Protease Inhibitors / pharmacology; Protein Transport / drug effects; Rats; Sus scrofa; Tumor Necrosis Factor-alpha / antagonists & inhibitors; Tumor Necrosis Factor-alpha / metabolism
topics (OpenAlex): Gastrointestinal motility and disorders; Dermatology and Skin Diseases; Acupuncture Treatment Research Studies
TL;DR: Investigating the mechanisms by which CRF mediates intestinal epithelial barrier disturbances demonstrated that CRF triggers increases in intestinal paracellular permeability via mast cell dependent release of TNF-α and proteases, hallmarks of IBS and IBD. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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