Emily Mihalko

Krissanaprasit, A., Mihalko, E., Meinhold, K., Simpson, A., Sollinger, J., Pandit, S., … LaBean, T. H. (2024). A Functional RNA-Origami as Direct Thrombin Inhibitor with Fast-acting and Specific Single-Molecule Reversal Agents in vivo model. Molecular Therapy, 32(7), 2286–2298. https://doi.org/10.1016/j.ymthe.2024.05.002

Sheridan, A., Nellenbach, K., Pandit, S., Byrnes, E., Hardy, G., Lutz, H., … Brown, A. C. (2024, June 5). Clot-Targeted Nanogels for Dual-Delivery of AntithrombinIII and Tissue Plasminogen Activator to Mitigate Disseminated Intravascular Coagulation Complications. ACS NANO, Vol. 6. https://doi.org/10.1021/acsnano.4c00162

Nellenbach, K., Mihalko, E., Nandi, S., Koch, D. W., Shetty, J., Moretti, L., … Brown, A. C. (2024). Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma. SCIENCE TRANSLATIONAL MEDICINE, 16(742). https://doi.org/10.1126/scitranslmed.adi4490

Chee, E., Mihalko, E., Nellenbach, K., Sollinger, J., Huang, K., Hon, M., … Brown, A. (2023). Wound‐triggered shape change microgels for the development of enhanced biomimetic function platelet‐like particles. Journal of Biomedical Materials Research Part A, 112(4), 613–624. https://doi.org/10.1002/jbm.a.37625

Mihalko, E. P., Sandry, M., Mininni, N., Nellenbach, K., Deal, H., Daniele, M., … Brown, A. C. (2021). Fibrin-modulating nanogels for treatment of disseminated intravascular coagulation. Blood Advances, 5(3), 613–627. https://doi.org/10.1182/bloodadvances.2020003046

Mihalko, E. P., Nellenbach, K., Krishnakumar, M., Moiseiwitsch, N., Sollinger, J., Cooley, B. C., & Brown, A. C. (2021). Fibrin‐specific <scp>poly(N‐isopropylacrylamide)</scp> nanogels for targeted delivery of tissue‐type plasminogen activator to treat thrombotic complications are well tolerated in vivo. Bioengineering & Translational Medicine, 7(2). https://doi.org/10.1002/btm2.10277

Krissanaprasit, A., Key, C. M., Froehlich, K., Pontula, S., Mihalko, E., Dupont, D. M., … LaBean, T. H. (2021). Multivalent Aptamer‐Functionalized Single‐Strand RNA Origami as Effective, Target‐Specific Anticoagulants with Corresponding Reversal Agents. Advanced Healthcare Materials, 10(11). https://doi.org/10.1002/adhm.202001826

Todd, J., Bharadwaj, V. N., Nellenbach, K., Nandi, S., Mihalko, E., Copeland, C., … Stabenfeldt, S. E. (2021). Platelet‐like</scp> particles reduce <scp>coagulopathy‐related</scp> and neuroinflammatory pathologies <scp>post‐experimental</scp> traumatic brain injury. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 109(12), 2268–2278. https://doi.org/10.1002/jbm.b.34888

Nandi, S., Mihalko, E., Nellenbach, K., Castaneda, M., Schneible, J., Harp, M., … Brown, A. C. (2021). Synthetic Platelet Microgels Containing Fibrin Knob B Mimetic Motifs Enhance Clotting Responses. Advanced Therapeutics, 4(5). https://doi.org/10.1002/adtp.202100010

Chee, E., Nandi, S., Nellenbach, K., Mihalko, E., Snider, D. B., Morrill, L., … Brown, A. C. (2020). Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet‐like particles. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 108(6), 2599–2609. https://doi.org/10.1002/jbm.b.34592

Nandi, S., Sommerville, L., Nellenbach, K., Mihalko, E., Erb, M., Freytes, D. O., … Brown, A. C. (2020). Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects. Journal of Colloid and Interface Science, 577, 406–418. https://doi.org/10.1016/j.jcis.2020.05.088

Mihalko, E., & Brown, A. C. (2019). Clot Structure and Implications for Bleeding and Thrombosis. Seminars in Thrombosis and Hemostasis, 46(01), 096–104. https://doi.org/10.1055/s-0039-1696944

Tang, J., Su, T., Huang, K., Dinh, P.-U., Wang, Z., Vandergriff, A., … Cheng, K. (2018). Targeted repair of heart injury by stem cells fused with platelet nanovesicles. Nature Biomedical Engineering, 2(1), 17–26. https://doi.org/10.1038/s41551-017-0182-x

Mihalko, E. P., & Brown, A. C. (2017). Material Strategies for Modulating Epithelial to Mesenchymal Transitions. ACS Biomaterials Science & Engineering, 4(4), 1149–1161. https://doi.org/10.1021/acsbiomaterials.6b00751