Works (4)

Updated: July 5th, 2023 15:52

2022 journal article

Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy


By: H. Li*, Z. Wang*, E. Archibong, Q. Wu*, G. Chen*, Q. Hu n, T. Ci*, Z. Chen* ...

author keywords: drug delivery; CAR T therapy; microneedle patch; solid tumor treatment; cell delivery
TL;DR: A porous microneedle patch is implemented that accommodates CAR T cells and allows in situ penetration-mediated seeding ofCAR T cells when implanted in the tumor bed or in the post-surgical resection cavity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: March 28, 2022

2021 article

Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets

Hu, Q., Li, H., Archibong, E., Chen, Q., Ruan, H., Ahn, S., … Gu, Z. (2021, April 26). NATURE BIOMEDICAL ENGINEERING.

By: Q. Hu*, H. Li*, E. Archibong n, Q. Chen*, H. Ruan*, S. Ahn*, E. Dukhovlinova*, Y. Kang* ...

MeSH headings : Animals; Antibodies, Monoclonal, Humanized; Blood Platelets; Cell-Derived Microparticles; Hydrogels; Immunotherapy, Adoptive; Mice; Neoplasm Recurrence, Local / prevention & control; T-Lymphocytes; Tumor Microenvironment
TL;DR: A hydrogel implanted into the cavity of a resected tumour and releasing CAR-T cells and platelets conjugated with a checkpoint inhibitor inhibits local tumour recurrence and the growth of distant tumours in mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021

2017 journal article

Synthetic beta cells for fusion-mediated dynamic insulin secretion

Nature Chemical Biology, 14(1), 86–93.

By: Z. Chen n, J. Wang n, W. Sun n, E. Archibong n, A. Kahkoska*, X. Zhang n, Y. Lu n, F. Ligler n, J. Buse*, Z. Gu n

MeSH headings : Animals; Artificial Cells; Biomimetic Materials / chemistry; Blood Glucose / analysis; Cell Engineering / methods; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Hydrogen-Ion Concentration; Insulin / blood; Insulin / metabolism; Insulin Secretion; Insulin-Secreting Cells / metabolism; Male; Membrane Fusion; Mice, Inbred C57BL
TL;DR: The construction of artificial beta cells with a multicompartmental 'vesicles-in-vesicle' superstructure equipped with a glucose-metabolism system and membrane-fusion machinery is described, which can effectively distinguish between high and normal glucose levels. (via Semantic Scholar)
Sources: Web Of Science, Crossref
Added: August 6, 2018

1989 journal article


BIOLOGY OF REPRODUCTION, 41(6), 1076–1083.

By: A. Archibong n, R. Petters n & B. Johnson n

MeSH headings : Animals; Blastocyst / physiology; Body Fluids / physiology; Culture Media; Culture Techniques; Embryo, Mammalian / physiology; Fallopian Tubes / physiology; Female; Luteal Phase / physiology; Swine / embryology
TL;DR: Investigation of in vitro development of 1-cell and 2-cell porcine embryos in a modified Kreb's Ringer bicarbonate medium found development to blastocyst stage was lowest among embryos cultured in OVF and highest among those cultured in CM-OVF. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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