Works (25)

Updated: April 12th, 2024 05:00

2024 article

Antibodies to <i>Borrelia burgdorferi</i> and <i>Bartonella</i> species in serum and synovial fluid from people with rheumatic diseases

Kim, L., Lashnits, E., Breitschwerdt, E. B., Elam, A., Grade, N., Miller, J., & Shikhman, A. R. (2024, March 14). MICROBIOLOGY SPECTRUM, Vol. 3.

By: L. Kim*, E. Lashnits*, E. Breitschwerdt n, A. Elam*, N. Grade*, J. Miller*, A. Shikhman

author keywords: antibodies; Bartonella; Borrelia burgdorferi; immunoserology; Lyme; serodiagnosis; rheumatology
Sources: Web Of Science, NC State University Libraries
Added: April 8, 2024

2023 article

Blood Supplementation Enhances Bartonella henselae Growth and Molecular Detection of Bacterial DNA in Liquid Culture

Liedig, C., Neupane, P., Lashnits, E., Breitschwerdt, E. B., & Maggi, R. G. (2023, May 25). (H. H. Mostafa, Ed.). MICROBIOLOGY SPECTRUM, Vol. 5.

By: C. Liedig n, P. Neupane*, E. Lashnits*, E. Breitschwerdt n & R. Maggi n

Ed(s): H. Mostafa

author keywords: BAPGM; Bartonella culture; Bartonella henselae; bartonellosis; blood supplementation; diagnostics
MeSH headings : Humans; Animals; Horses / genetics; Dogs; Sheep; Bartonella henselae / genetics; DNA, Bacterial / genetics; DNA, Bacterial / analysis; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella / genetics; Dietary Supplements; Mammals
TL;DR: The addition of sheep blood to liquid culture media increased the Bartonella henselae DNA concentration compared to controls, additionally improving PCR direct detection sensitivity. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 26, 2023

2023 journal article

Evaluation of SARS-CoV-2 identification methods through surveillance of companion animals in SARS-CoV-2-positive homes in North Carolina, March to December 2020

PEERJ, 11.

By: T. Gin n, E. Petzold*, D. Uthappa*, C. Neighbors*, A. Borough*, C. Gin n, E. Lashnits*, G. Sempowski* ...

author keywords: COVID-19; Coronavirus; SARS-CoV-2; Dogs; Cats; Antibody; Serology
TL;DR: Raw ELISA results scrutinized relative to known negative samples suggested that cut-off for IgG seropositivity may require adjustment relative to previously proposed values, while proposed cut-offs for IgM require more extensive validation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 27, 2023

2023 journal article

Feeding on a Bartonella henselae Infected Host Triggers Temporary Changes in the Ctenocephalides felis Microbiome

PATHOGENS, 12(3).

By: C. Moore, E. Lashnits n, P. Neupane n, B. Herrin*, M. Lappin*, M. Andre*, E. Breitschwerdt n

author keywords: Bartonella henselae; Ctenocephalides felis; flea; microbiome; wolbachia; vector microbiome
TL;DR: Using Next Generation Sequencing (NGS) on the Illumina platform, an increase in microbial diversity in C. felis microbiome when fed on B. henselae-infected cats is documented, which may be related to the mammalian, flea, or endosymbiont response. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 23, 2023

2022 journal article

Bartonella henselae Recombinant Pap31 for the Diagnosis of Canine and Human Bartonelloses

PATHOGENS, 11(2).

By: P. Neupane n, R. Maggi n, M. Basnet*, E. Lashnits*, G. Andrews* & E. Breitschwerdt n

author keywords: antigen; Bartonella henselae; serology; diagnosis; ELISA; Western blot; heme binding proteins
TL;DR: It is indicated that recombinant Pap31 and the selected fragments may not be appropriate diagnostic targets in detecting anti-Bartonella antibodies in Bartonella-infected dogs and humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 2, 2022

2022 journal article

Identification of microbial taxa present in Ctenocephalides felis (cat flea) reveals widespread co-infection and associations with vector phylogeny

PARASITES & VECTORS, 15(1).

By: C. Manvell n, H. Berman n, B. Callahan n, E. Breitschwerdt n, W. Swain n, K. Ferris n, R. Maggi n, E. Lashnits*

author keywords: Flea microbiome; Bartonella; Wolbachia; Rickettsia; Flea phylogenetics; Flea diversity; DNA barcoding; 16S NGS
MeSH headings : Animals; Cats; Bartonella / genetics; Cat Diseases / parasitology; Coinfection; Ctenocephalides / microbiology; Flea Infestations / epidemiology; Flea Infestations / veterinary; Phylogeny; Rickettsia / genetics
TL;DR: The findings confirm the widespread coinfection of fleas with multiple bacterial genera and strains, proposing three additional microbiome members and have important implications for flea-borne pathogen transmission and control. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 14, 2022

2022 article

Outcomes of esophageal and gastric bone foreign bodies in dogs

Barash, N. R., Lashnits, E., Kern, Z. T., Tolbert, M. K., & Lunn, K. F. (2022, February 14). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 2.

By: N. Barash n, E. Lashnits n, Z. Kern n, M. Tolbert n & K. Lunn n

author keywords: endoscopy; erosion; esophagus; stomach
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / surgery; Dogs; Endoscopy / veterinary; Esophageal Diseases / veterinary; Foreign Bodies / complications; Foreign Bodies / surgery; Foreign Bodies / veterinary; Retrospective Studies; Stomach
TL;DR: While all E‐bFBs were dislodged either by advancement into the stomach, endoscopic removal, or esophagotomy, the majority of gastric bone foreign bodies were left in situ for dissolution, with no reported complications. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 15, 2022

2021 article

Bartonella spp. seroepidemiology and associations with clinicopathologic findings in dogs in the United States

Lashnits, E., Thatcher, B., Carruth, A., Mestek, A., Buch, J., Beall, M., … Breitschwerdt, E. B. (2021, November 17). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 36.

By: E. Lashnits n, B. Thatcher*, A. Carruth*, A. Mestek*, J. Buch*, M. Beall*, P. Neupane n, R. Chandrashekar*, E. Breitschwerdt n

author keywords: bartonellosis; canine; seroreactivity; vector-borne; zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dogs; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Demographic and geographic findings for Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 18, 2021

2021 journal article

Comparison of Serological and Molecular Assays for Bartonella Species in Dogs with Hemangiosarcoma

PATHOGENS, 10(7).

By: E. Lashnits n, P. Neupane n, J. Bradley n, T. Richardson n, R. Maggi n & E. Breitschwerdt n

author keywords: diagnostic testing; ddPCR; PCR; serology; sensitivity; specificity; tissue biopsy; latent class analysis
TL;DR: Data indicate that Bartonella spp. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 24, 2021

2021 journal article

Demographics and travel history of imported and autochthonous cases of leishmaniosis in dogs in the United States and Canada, 2006 to 2019

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(2), 954–964.

By: T. Gin n, E. Lashnits n, J. Wilson n, E. Breitschwerdt n & B. Qurollo n

author keywords: dog; leishmania; lutzomyia
MeSH headings : Animals; Canada / epidemiology; Demography; Dog Diseases / epidemiology; Dogs; Leishmania infantum; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Leishmania surveillance should be considered for dogs that return from L. infantum‐endemic regions to monitor emergence of this zoonotic disease in the US and Canada, and several nonfoxhound breeds had no travel history. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 27, 2021

2021 journal article

Prevalence of Vector-Borne Pathogens in Reproductive and Non-Reproductive Tissue Samples from Free-Roaming Domestic Cats in the South Atlantic USA

PATHOGENS, 10(9).

By: C. Manvell n, K. Ferris n, R. Maggi n, E. Breitschwerdt n & E. Lashnits n

author keywords: Bartonella spp; hemotropic Mycoplasma spp; reproduction; cats; prevalence
TL;DR: Ear tip and reproductive tissues of FRCs from two locations in the South Atlantic United States for Anaplasma, Bartonella, Ehrlichia, hemotropic Mycoplasma, and Rickettsia species suggest that B. henselae preferentially infected cats’ reproductive tissue and reinforces the importance of investigating the potential for vertical transmission or induction of reproductive failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 22, 2021

2021 journal article

Schizophrenia and Bartonella spp. Infection: A Pilot Case-Control Study

VECTOR-BORNE AND ZOONOTIC DISEASES, 21(6), 413–421.

By: E. Lashnits n, R. Maggi n, F. Jarskog*, J. Bradley n, E. Breitschwerdt n & F. Frohlich*

author keywords: vector-borne disease; infectious disease; cat; epidemiology; ddPCR; cat scratch disease
MeSH headings : Animals; Bartonella / genetics; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Case-Control Studies; Pilot Projects; Schizophrenia
TL;DR: Preliminary evidence in support of future investigations that should examine a potential contribution of Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021

2020 journal article

A retrospective study of vector‐borne disease prevalence in dogs with proteinuria: Southeastern United States

Journal of Veterinary Internal Medicine, 1.

By: E. Purswell n, E. Lashnits n, E. Breitschwerdt n & S. Vaden n

author keywords: anaplasmosis; ehrlichiosis; flea; immune-mediated; rickettsioses; tick
MeSH headings : Animals; Cross-Sectional Studies; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Female; Male; Prevalence; Proteinuria / veterinary; Retrospective Studies; Risk Factors; Seasons; Southeastern United States / epidemiology; Vector Borne Diseases / epidemiology; Vector Borne Diseases / veterinary
TL;DR: Exposure to CVBD, particularly exposure to Rickettsia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: January 9, 2020

2020 journal article

Bartonella Associated Cutaneous Lesions (BACL) in People with Neuropsychiatric Symptoms

Pathogens, 9(12), 1023.

By: E. Breitschwerdt n, J. Bradley n, R. Maggi n, E. Lashnits n & P. Reicherter*

author keywords: infection; bacteria; psychoses; transmission; stretch marks; bartonella; neuropsychiatric; cutaneous lesions; BACL
TL;DR: It is concluded that cutaneous lesions were common among people reporting neuropsychiatric symptoms and Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: December 5, 2020

2020 journal article

Detection of Bartonella spp. in dogs after infection with Rickettsia rickettsii

Journal of Veterinary Internal Medicine, 34(1), 145–159.

By: E. Lashnits n, P. Neupane n, R. Maggi n, K. Linder n, J. Bradley n, N. Balakrishnan n, B. Southern n, G. McKeon n, R. Chandrashekar*, E. Breitschwerdt n

author keywords: PCR; recrudescence; serology; transmission
MeSH headings : Animals; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Coinfection; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Female; Housing, Animal; Laboratory Animal Science; Rickettsia rickettsii; Rocky Mountain Spotted Fever / complications; Rocky Mountain Spotted Fever / microbiology; Rocky Mountain Spotted Fever / veterinary; Serologic Tests
TL;DR: The results support the possibilities of recrudescence of chronic subclinical Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: January 1, 2020

2020 journal article

Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States

PLOS ONE.

By: E. Lashnits n, P. Neupane n, J. Bradley n, T. Richardson n, R. Thomas n, K. Linder n, M. Breen n, R. Maggi n, E. Breitschwerdt n

Ed(s): D. Thamm

MeSH headings : Animals; Babesia / genetics; Babesiosis / epidemiology; Babesiosis / parasitology; Bartonella / genetics; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Female; Hemangiosarcoma / epidemiology; Hemangiosarcoma / microbiology; Hemangiosarcoma / parasitology; Hemangiosarcoma / veterinary; Male; Mycoplasma / genetics; Mycoplasma Infections / epidemiology; Mycoplasma Infections / veterinary; Polymerase Chain Reaction; Prevalence; Retrospective Studies; United States / epidemiology
TL;DR: A high prevalence of Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: January 11, 2020

2020 journal article

Serum procalcitonin concentrations in dogs with induced endotoxemia

Journal of Veterinary Internal Medicine, 1.

By: F. Easley n, M. Holowaychuk, E. Lashnits n, S. Nordone n, H. Marr n & A. Birkenheuer n

author keywords: animal model; biomarker; lipopolysaccharide; sepsis
MeSH headings : Animals; Cross-Over Studies; Dog Diseases / blood; Dog Diseases / chemically induced; Dogs; Endotoxemia / blood; Endotoxemia / chemically induced; Endotoxemia / veterinary; Lipopolysaccharides / toxicity; Male; Procalcitonin / blood
TL;DR: Procalcitonin expression is likely to be a clinically useful biomarker for sepsis in dogs and might have an additional role in prognostication and therapeutic decision‐making. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: January 23, 2020

2019 journal article

Ecological and Socioeconomic Factors Associated with Bartonella henselae Exposure in Dogs Tested for Vector-Borne Diseases in North Carolina

Vector-Borne and Zoonotic Diseases, 19(8), 582–595.

By: E. Lashnits n, D. Dawson n, E. Breitschwerdt n & C. Lanzas n

author keywords: canine; seroreactivity; tick; flea; zoonoses; vector-borne
MeSH headings : Animals; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Ecosystem; Female; Male; North Carolina / epidemiology; Retrospective Studies; Risk Factors; Seroepidemiologic Studies; Socioeconomic Factors; Tick-Borne Diseases / epidemiology
TL;DR: Of 25 explanatory factors considered, the model combining demographic, socioeconomic, climatic, and land use variables fits best, and female intact sex and increasing percentage of the county with low-intensity development and evergreen forest were associated with higher seroreactivity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 4, 2019

2019 journal article

Evidence for vertical transmission of Mycoplasma haemocanis, but not Ehrlichia ewingii, in a dog

Journal of Veterinary Internal Medicine, 33(4), 1747–1752.

By: E. Lashnits n, S. Grant, B. Thomas n, B. Qurollo n & E. Breitschwerdt n

author keywords: bacterial species; hemotropic mycoplasma; perinatal; rickettsia; vector-borne
MeSH headings : Animals; Antibodies, Bacterial; Coinfection / veterinary; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Ehrlichia / isolation & purification; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Female; Infectious Disease Transmission, Vertical / veterinary; Male; Mycoplasma / isolation & purification; Mycoplasma Infections / transmission; Mycoplasma Infections / veterinary; Pregnancy
TL;DR: A potential role for vertical transmission in the maintenance of M. haemocanis in dogs as reservoir hosts is supported and there is no evidence that E. ewingii was transmitted transplacentally or during the perinatal period. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: May 27, 2019

2017 journal article

Bartonella Seroepidemiology in Dogs from North America, 2008-2014

Journal of Veterinary Internal Medicine, 32(1), 222–231.

By: E. Lashnits n, M. Correa n, B. Hegarty n, A. Birkenheuer n & E. Breitschwerdt n

author keywords: Canine; Seroreactivity; Zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Male; North America / epidemiology; Seroepidemiologic Studies; Spatio-Temporal Analysis
TL;DR: Male intact dogs, mixed breed dogs, and dogs exposed to other CVBD have higher seroreactivity to multiple Bartonella species, and geographic patterns supported broad distribution of exposure, and co‐exposure with otherCVBD was common. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Scleromyxoedema in a dog

Veterinary Dermatology, 28(5), 119–503.

By: A. Laprais n, P. Bizikova n, E. Lashnits n, A. Tucker* & K. Linder n

Contributors: A. Laprais n, P. Bizikova n, E. Lashnits n, A. Tucker* & K. Linder n

MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Female; Scleromyxedema / diagnosis; Scleromyxedema / pathology; Scleromyxedema / veterinary; Skin / pathology; Skin Diseases / diagnosis; Skin Diseases / pathology; Skin Diseases / veterinary
TL;DR: Systemic evaluation is important to identify evidence of internal disease and associated comorbidities, which are common, variable, and impact classification and prognosis in humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: February 12, 2019

2011 journal article

Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation

American Journal of Pathology, 178(6), 2897–2909.

By: J. Fuxe*, S. Tabruyn*, K. Colton*, H. Zaid*, A. Adams*, P. Baluk*, E. Lashnits*, T. Morisada* ...

Contributors: J. Fuxe*, S. Tabruyn*, K. Colton*, H. Zaid*, A. Adams*, P. Baluk*, E. Lashnits*, T. Morisada* ...

MeSH headings : Actins / metabolism; Angiopoietin-1 / metabolism; Animals; Aptamers, Nucleotide / pharmacology; Bradykinin / pharmacology; Cell Count; Cell Shape / drug effects; Desmin / metabolism; Inflammation / complications; Inflammation / pathology; Mice; Mice, Inbred C57BL; Microspheres; Mycoplasma Infections / complications; Mycoplasma Infections / pathology; Mycoplasma pulmonis / drug effects; Mycoplasma pulmonis / physiology; Pericytes / drug effects; Pericytes / microbiology; Pericytes / pathology; Proto-Oncogene Proteins c-sis / antagonists & inhibitors; Proto-Oncogene Proteins c-sis / metabolism; Receptor, Platelet-Derived Growth Factor beta / metabolism; Recombinant Fusion Proteins / pharmacology; Trachea / blood supply; Trachea / microbiology; Trachea / pathology
TL;DR: Pericyte contributions to endothelial stability have greater dependence on PDGF-B during the development of sustained inflammation, when pericyte dynamics accompany vascular remodeling, than under baseline conditions or in acute inflammation. (via Semantic Scholar)
Source: ORCID
Added: February 12, 2019

2010 journal article

Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation

American Journal of Pathology, 176(4), 2009–2018.

By: J. Fuxe*, E. Lashnits*, S. O’Brien*, P. Baluk*, S. Tabruyn*, F. Kuhnert*, C. Kuo*, G. Thurston*, D. McDonald*

Contributors: J. Fuxe*, E. Lashnits*, . S. O'Brien, P. Baluk*, S. Tabruyn*, F. Kuhnert*, C. Kuo*, G. Thurston*, D. McDonald*

MeSH headings : Adenoviridae / metabolism; Angiopoietin-1 / metabolism; Animals; Biological Transport; Capillaries / metabolism; Inflammation; Intercellular Adhesion Molecule-1 / biosynthesis; Leukocytes / cytology; Mice; Mice, Inbred C57BL; Mycoplasma pulmonis / metabolism; Receptor, TIE-2 / metabolism; Signal Transduction; Vascular Endothelial Growth Factor A / metabolism; Venules / metabolism
TL;DR: It is reported that the angiopoietin/Tie2 pathway is an essential driving force for capillary remodeling into venules in M. pulmonis-infected mouse airways, and blockade of the Ang/TIE2 pathway may represent a therapeutic approach in airway inflammation. (via Semantic Scholar)
Source: ORCID
Added: February 12, 2019

2010 journal article

Rapid remodeling of airway vascular architecture at birth

Developmental Dynamics, 239(9), 2354–2366.

By: A. Ni*, E. Lashnits*, L. Yao*, P. Baluk* & D. McDonald*

Contributors: A. Ni*, E. Lashnits*, L. Yao*, P. Baluk* & D. McDonald*

author keywords: respiratory tract; blood vessels; angiogenesis, vascular regression; hypoxia; VEGF
MeSH headings : Animals; Animals, Newborn; Apoptosis / physiology; Blood Vessels / anatomy & histology; Blood Vessels / embryology; Blood Vessels / growth & development; Cell Proliferation; Endothelial Cells / cytology; Endothelial Cells / physiology; Female; Hypoxia / metabolism; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Lung / blood supply; Lung / embryology; Lung / growth & development; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic / physiology; Pregnancy; Vascular Endothelial Growth Factor Receptor-2 / antagonists & inhibitors
TL;DR: Findings reveal the plasticity of airway vasculature after birth and show that these vessels can be used to elucidate factors that promote postnatal vascular remodeling and maturation. (via Semantic Scholar)
Source: ORCID
Added: February 12, 2019

2007 journal article

Functionally specialized junctions between endothelial cells of lymphatic vessels

Journal of Experimental Medicine, 204(10), 2349–2362.

By: P. Baluk*, J. Fuxe*, H. Hashizume*, T. Romano*, E. Lashnits*, S. Butz*, D. Vestweber*, M. Corada* ...

Contributors: P. Baluk*, J. Fuxe*, H. Hashizume*, T. Romano*, E. Lashnits*, S. Butz*, D. Vestweber*, M. Corada* ...

MeSH headings : Animals; Cadherins / metabolism; Cell Movement; Endothelial Cells / cytology; Endothelial Cells / immunology; Endothelial Cells / metabolism; Lymphatic Vessels / cytology; Lymphatic Vessels / immunology; Lymphatic Vessels / metabolism; Lymphocytes / cytology; Lymphocytes / immunology; Mice; Mice, Inbred C57BL; Platelet Endothelial Cell Adhesion Molecule-1 / genetics; Platelet Endothelial Cell Adhesion Molecule-1 / metabolism
TL;DR: It is suggested that fluid enters throughoutInitial lymphatics via openings between buttons, which open and close without disrupting junctional integrity, but most leukocytes enter the proximal half of initial lymphatics. (via Semantic Scholar)
Source: ORCID
Added: February 12, 2019

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