Works (33)

Updated: July 25th, 2023 05:04

2023 article

CADMIUM EXPOSURE AFFECTS THE PROGRESSION OF HUMAN METASTATIC MELANOMA BY INDUCING A DEREGULATION OF ANTIOXIDANT CELL RESPONSE

Casoni, A., Benedusi, M., Cervellati, F., Pecorelli, A., Ferrara, F., Vallese, A., & Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 42–43.

By: A. Casoni*, M. Benedusi*, F. Cervellati*, A. Pecorelli*, F. Ferrara*, A. Vallese*, G. Valacchi n

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

CONSTITUTIVE ACTIVATION OF NLRP3 INFLAMMASOME MACHINERY IN EX-VIVO MODELS OF RETT SYNDROME: FROM PATHOGENETIC ROLE TO NEW POTENTIAL THERAPEUTIC TARGET

Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 12–12.

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

Caffeic acid-loaded lipid nanoparticles as a tool to protect skin against oxidative stress: formulation and evaluation on human skin explants

Sguizzato, M., Ferrara, F., Valacchi, G., Cortesi, R., & Esposito, E. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S19–S19.

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

Deregulated NLRP3 inflammasome response due to a constitutive activation of NF-kappa B p65 pro-inflammatory pathway in lymphomonocytes of Rett syndrome patients

Cordone, V., Vallese, A., Pecorelli, A., Guiotto, A., Ferrara, F., Benedusi, M., … Valacchi, G. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S21–S22.

By: V. Cordone*, A. Vallese*, A. Pecorelli n, A. Guiotto*, F. Ferrara*, M. Benedusi*, F. Cervellati*, J. Hayek*, G. Valacchi n

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 journal article

Evaluation of Anti-Oxinflammatory and ACE-Inhibitory Properties of Protein Hydrolysates Obtained from Edible Non-Mulberry Silkworm Pupae (Antheraea assama and Philosomia ricinii)

NUTRIENTS, 15(4).

author keywords: non-mulberry silkworm pupae; angiotensin converting enzyme-inhibitory peptides; antioxidative peptides; ultrafiltration; anti-inflammatory peptides
MeSH headings : Animals; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Antioxidants / pharmacology; Protein Hydrolysates / pharmacology; Bombyx; Pupa; Endothelial Cells; Lipopolysaccharides; Peptides / pharmacology; Hypertension; Hydrolysis
Sources: Web Of Science, ORCID
Added: March 20, 2023

2023 article

INFLAMMASOMES REGULATION BY ENVIRONMENTAL POLLUTANTS IN HUMAN SKIN

Ferrara, F., Pecorelli, A., Guiotto, A., Vallese, A., Cordone, V., Benedusi, M., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 38–39.

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

MITOCHONDRIAL DYSFUNCTION AND NLRP3 INFLAMMASOME ACTIVATION IN AUTISM SPECTRUM DISORDER

Vallese, A., Pecorelli, A., Cordone, V., Ferrara, F., Benedusi, M., Cervellati, F., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 20–20.

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

THE POSSIBLE MODULATION OF NRF2 AND NF-KB CROSSTALK BY SULFORAPHANE IN THE PROGRESSION OF HUMAN MELANOMA

Benedusi, M., Canella, R., Vallese, A., Casoni, A., Guerra, M., Rispoli, G., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 57–57.

By: M. Benedusi*, R. Canella*, A. Vallese*, A. Casoni*, M. Guerra*, G. Rispoli*, F. Ferrara*, F. Cervellati*, G. Valacchi n

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

THE PROTECTIVE ROLE OF ENDOTHELIAL alpha 1AMPK IN AIRCRAFT NOISE-INDUCED VASCULAR DYSFUNCTION AND OXIDATIVE STRESS IS MEDIATED BY FASTING, EXERCISE AND PHARMACOLOGICAL TREATMENT

Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 11–12.

By: V. Cordone, A. Pecorelli, F. Ferrara, A. Guiotto, J. Hayek, C. Cervellati, F. Amicarelli, G. Valacchi

Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 journal article

Topical Application of M89PF Containing Vichy Mineralising Water and Probiotic Fractions Prevents Cutaneous Damage Induced by Exposure to UV and O3

CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY, 16, 1769–1776.

By: M. Benedusi, D. Kerob, A. Guiotto*, F. Cervellati, F. Ferrara* & E. Pambianchi*

author keywords: ultraviolet radiation; ozone; skin barrier; oxidative stress; inflammation
Source: Web Of Science
Added: July 24, 2023

2022 journal article

Ethosomes and Transethosomes as Cutaneous Delivery Systems for Quercetin: A Preliminary Study on Melanoma Cells

PHARMACEUTICS, 14(5).

author keywords: quercetin; ethosome; transethosome; in vitro release test; in vitro permeation test; Franz cell; wound healing; migration assay
Sources: Web Of Science, ORCID
Added: June 13, 2022

2022 journal article

Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals

ANTIOXIDANTS, 11(3).

By: L. Pozzetti*, F. Ferrara*, L. Marotta*, S. Gemma*, S. Butini*, M. Benedusi*, F. Fusi*, A. Ahmed* ...

author keywords: olive oil; traceability quality; food origin; luteolin; oleuropein; CaCo-2 cells; Nrf2; NF-kappa B
Sources: Web Of Science, ORCID
Added: April 18, 2022

2022 article

Loss of Scavenger Receptor B1 (SR-B1) in Brain of a Rett Syndrome Mouse Model

Pecorelli, A., Ferrara, F., Guiotto, A., Vallese, A., Cordone, V., Belmonte, G., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.

By: A. Pecorelli*, F. Ferrara*, A. Guiotto, A. Vallese*, V. Cordone, G. Belmonte, J. Hayek, C. Cervellati, G. Valacchi*

Sources: Web Of Science, ORCID
Added: March 6, 2023

2022 journal article

The constitutive activation of TLR4-IRAK1-NF kappa B axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients

FREE RADICAL BIOLOGY AND MEDICINE, 181, 1–13.

author keywords: MeCP2; p65; Oxinflammation; Interleukin-18; Interleukin-1 beta
MeSH headings : Humans; Inflammasomes / genetics; Inflammasomes / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; Leukocytes, Mononuclear / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Toll-Like Receptor 4 / genetics
Sources: Web Of Science, ORCID
Added: March 14, 2022

2022 journal article

Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation

REDOX BIOLOGY, 56.

author keywords: Inflammasomes; OxInflammation; Proteasome; UBR2; N-end rule pathway
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Air Pollutants; Apoptosis Regulatory Proteins / genetics; Catalase / metabolism; Cytokines / metabolism; Environmental Pollutants; Humans; Hydrogen Peroxide / metabolism; Inflammasomes / metabolism; NLR Proteins / metabolism; Oxidation-Reduction; Ozone / metabolism; Particulate Matter; Reactive Oxygen Species / metabolism; Ubiquitin-Protein Ligases / metabolism; Ubiquitination
Sources: Web Of Science, ORCID
Added: September 12, 2022

2022 article

Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation

Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.

By: F. Ferrara*, V. Cordone*, A. Pecorelli n, M. Benedusi*, E. Pambianchi n, A. Guiotto*, A. Vallese*, F. Cervellati*, G. Valacchi n

Sources: Web Of Science, ORCID
Added: March 6, 2023

2021 journal article

"Plurethosome" as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation

PHARMACEUTICS, 13(8).

By: M. Sguizzato*, F. Ferrara*, P. Mariani*, A. Pepe*, R. Cortesi*, N. Huang*, F. Simeliere*, P. Boldrini* ...

author keywords: phosphatidylcholine; poloxamer; mangiferin; in vitro diffusion; antioxidant
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Deferoxamine Treatment Improves Antioxidant Cosmeceutical Formulation Protection against Cutaneous Diesel Engine Exhaust Exposure

ANTIOXIDANTS, 10(12).

By: E. Pambianchi n, F. Ferrara*, A. Pecorelli n, M. Benedusi*, H. Choudhary*, J. Therrien*, G. Valacchi n

author keywords: cosmeceuticals; pollution; iron-chelator
Sources: Web Of Science, ORCID
Added: January 24, 2022

2021 journal article

Inflammasome Activation in Pollution-Induced Skin Conditions

PLASTIC AND RECONSTRUCTIVE SURGERY, 147(1S-2), 15S–24S.

By: F. Ferrara n, R. Prieux n, B. Woodby n & G. Valacchi n

MeSH headings : Air Pollutants / adverse effects; Air Pollution / adverse effects; Animals; Dermatitis / immunology; Dermatitis / pathology; Dermatitis / prevention & control; Disease Models, Animal; Environmental Exposure / adverse effects; Furans; Heterocyclic Compounds, 4 or More Rings / pharmacology; Heterocyclic Compounds, 4 or More Rings / therapeutic use; Humans; Indenes; Inflammasomes / antagonists & inhibitors; Inflammasomes / immunology; Inflammasomes / metabolism; Interleukin-18 / metabolism; Interleukin-1beta / metabolism; Mice; NLR Family, Pyrin Domain-Containing 3 Protein / antagonists & inhibitors; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Nitriles / pharmacology; Nitriles / therapeutic use; Skin / drug effects; Skin / immunology; Skin / pathology; Skin Aging / immunology; Sulfonamides; Sulfones / pharmacology; Sulfones / therapeutic use
Sources: Web Of Science, ORCID
Added: July 6, 2021

2021 article

NALP1 involvement in cigarette smoke induces cutaneous inflammation

Prieux, R., Benedusi, M., Ferrara, F., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

By: R. Prieux, M. Benedusi, F. Ferrara, A. Guiotto, F. Cervellati & G. Valacchi

Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 article

Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation

Ferrara, F., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

By: F. Ferrara, A. Pecorelli, M. Benedusi, E. Pambianchi, A. Guiotto, F. Cervellati, G. Valacchi

Sources: Web Of Science, ORCID
Added: April 5, 2021

2020 journal article

Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder

FASEB JOURNAL, 34(5), 6521–6538.

author keywords: 4-hydroxynonenal; fission; fusion; mitophagy; nuclear factor erythroid 2-related factor 2
MeSH headings : Adolescent; Adult; Autism Spectrum Disorder / metabolism; Autism Spectrum Disorder / pathology; Case-Control Studies; Child; Energy Metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; Humans; Male; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Dynamics; Mitochondrial Proteins / metabolism; Oxidative Stress; Young Adult
Sources: Web Of Science, ORCID
Added: April 20, 2020

2020 journal article

Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents Implications for oxidative UV damage

REDOX BIOLOGY, 37.

By: C. Kremslehner*, A. Miller*, R. Nica, I. Nagelreiter*, M. Narzt*, B. Golabi*, V. Vorstandlechner*, M. Mildner* ...

MeSH headings : Adult; Cell Differentiation; Cells, Cultured; Humans; Keratinocytes; Oxidative Stress; Pharmaceutical Preparations / metabolism; Skin / metabolism; Ultraviolet Rays / adverse effects
Source: Web Of Science
Added: January 25, 2021

2020 journal article

Mechanisms involved in the unbalanced redox homeostasis in osteoblastic cellular model of Alkaptonuria

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 690.

author keywords: Alkaptonuria; Osteoblast; Oxidative stress; Nrf2; Mitochondria; NADPH oxidase
MeSH headings : Alkaptonuria / metabolism; Cell Line; DNA-Binding Proteins / metabolism; Homeostasis / physiology; Homogentisic Acid / metabolism; Humans; Hydrogen Peroxide / metabolism; Mitochondria / metabolism; Mitochondria / ultrastructure; NADPH Oxidases / metabolism; NF-E2-Related Factor 2 / metabolism; Osteoblasts / cytology; Oxidation-Reduction; Oxidative Stress / physiology; Signal Transduction; Superoxide Dismutase / metabolism; Thioredoxins / metabolism
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(2), 112–119.

By: D. Nieman*, G. Valacchi*, L. Wentz*, F. Ferrara*, A. Pecorelli n, B. Woodby n, C. Sakaguchi*, A. Simonson*

author keywords: inflammation exercise; oxidative stress; peripheral blood mononuclear cells
Sources: Web Of Science, ORCID
Added: July 6, 2020

2020 journal article

Nanoparticulate Gels for Cutaneous Administration of Caffeic Acid

NANOMATERIALS, 10(5).

By: M. Sguizzato*, P. Mariani*, F. Ferrara*, M. Drechsler*, S. Hallan*, N. Huang*, F. Simeliere*, N. Khunti* ...

author keywords: solid lipid nanoparticles; caffeic acid; poloxamer; small angle X-ray scattering; cigarette smoke
Sources: Web Of Science, ORCID
Added: July 13, 2020

2020 journal article

Postexercise Inflammasome Activation and IL-1 beta Production Mitigated by Flavonoid Supplementation in Cyclists

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(6), 396–404.

By: D. Nieman*, F. Ferrara*, A. Pecorelli*, B. Woodby*, A. Hoyle*, A. Simonson*, G. Valacchi*

author keywords: cytokines; gasdermin D; IL-18; inflammation
Sources: Web Of Science, ORCID
Added: November 9, 2020

2020 journal article

Redox regulation of cutaneous inflammasome by ozone exposure

FREE RADICAL BIOLOGY AND MEDICINE, 152, 561–570.

By: F. Ferrara*, E. Pambianchi*, A. Pecorelli*, B. Woodby*, N. Messano*, J. Therrien, M. Lila*, G. Valacchi*

MeSH headings : Caspase 1 / metabolism; Humans; Hydrogen Peroxide; Inflammasomes / metabolism; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Oxidation-Reduction; Ozone / toxicity; Reactive Oxygen Species
Sources: Web Of Science, ORCID
Added: July 13, 2020

2019 article

HGA Induces Oxidative Damage in an Ostcoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms HGA Induces Oxidative Damage in an Osteoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms

Schiavone, M. L., Pecorelli, A., Woodby, B., Ferrara, F., Santucci, A., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S37–S38.

By: M. Schiavone, A. Pecorelli, B. Woodby, F. Ferrara, A. Santucci & G. Valacchi

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 journal article

Involvement of cutaneous SR-B1 in skin lipid homeostasis

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 666, 1–7.

By: X. Muresan*, M. Narzt*, B. Woodby n, F. Ferrara n, F. Gruber* & G. Valacchi n

author keywords: Scavenger receptor; Skin; Keratinocytes; Lipids; Ceramides; Cholesterol; Differentiation
MeSH headings : Cell Differentiation / physiology; Cells, Cultured; Filaggrin Proteins; Gene Expression Regulation; Homeostasis; Humans; Keratinocytes / cytology; Lipid Metabolism / genetics; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / physiology; Skin / cytology; Skin / metabolism
Sources: Web Of Science, ORCID
Added: June 17, 2019

2019 article

Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure

Ferrara, F., Pecorelli, A., Woodby, B., Pambianchi, E., Messano, N., Therrien, J. P., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23.

By: F. Ferrara, A. Pecorelli, B. Woodby, E. Pambianchi, N. Messano, J. Therrien, G. Valacchi

Sources: Web Of Science, ORCID
Added: December 2, 2019

2018 article

AtmO(3)spheric skin damage: The oxInflammation phenomena

Valacchi, G., Pecorelli, A., Pambianchi, E., Ferrara, F., & Lila, M. (2018, September). JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B15–B15.

By: G. Valacchi n, A. Pecorelli*, E. Pambianchi*, F. Ferrara n & M. Lila*

Sources: Web Of Science, ORCID
Added: October 19, 2018

2018 journal article

SR-B1 involvement in keratinocytes in vitro wound closure

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 658, 1–6.

By: X. Muresan*, C. Sticozzi*, G. Belmonte*, F. Cervellati*, F. Ferrara*, M. Lila n, G. Valacchi n

author keywords: Wound healing; Skin; Proliferation; Migration
MeSH headings : Cell Line, Transformed; Cell Movement / physiology; Cell Proliferation / physiology; Cyclin D1 / metabolism; Gene Knockout Techniques; Humans; Keratinocytes / cytology; Keratinocytes / physiology; Matrix Metalloproteinase 9 / metabolism; NF-kappa B p50 Subunit / metabolism; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / physiology; Skin / metabolism; Wound Healing / physiology
Sources: Web Of Science, ORCID
Added: November 26, 2018