Fadia Jamal Milhem

Works (4)

Updated: December 9th, 2024 08:35

2024 journal article

Biomarkers of Metabolic Adaptation to High Dietary Fats in a Mouse Model of Obesity Resistance

METABOLITES, 14(1).

By: F. Milhem n, L. Hamilton  n, E. Skates n, M. Wilson n, S. Johanningsmeier n & S. Komarnytsky n 

author keywords: body composition; metabolic inflexibility; metabolic rate; dietary fats; skeletal muscle remodeling; glucose tolerance; microbiome
TL;DR: It is shown that NR mice developed healthier fat/lean body mass ratios compared with the obesity-prone (super-responder, SR) phenotypes by upregulating gene expression networks that promote the accumulation of type 2a, fast-twitch, oxidative muscle tissues. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 26, 2024

2024 journal article

Obesity-Resistant Mice on a High-Fat Diet Display a Distinct Phenotype Linked to Enhanced Lipid Metabolism

NUTRIENTS, 16(1).

By: F. Milhem n, E. Skates*, M. Wilson* & S. Komarnytsky n 

author keywords: dietary fats; energy substrate; body composition; metabolic rate; individual variability; personalized nutrition
TL;DR: NR mice showed an increased ability to metabolize excessive dietary fats in skeletal muscle at the expense of reduced exercise capacity that persisted for the duration of the study, underscore the need for further comprehensive investigations into the mechanisms of obesity resistance. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 22, 2024

2024 journal article

The biochemical effects of carotenoids in orange carrots on the colonic proteome in a mouse model of diet-induced obesity

FRONTIERS IN NUTRITION, 11.

By: E. Balbuena n, F. Milhem n, B. Kiremitci n, T. Williams n , L. Collins n , Q. Shu n , A. Eroglu n 

Contributors: E. Balbuena n, F. Milhem n, B. Kiremitci n, T. Williams n , L. Collins n , Q. Shu n , A. Eroglu n 

author keywords: carotenoids; quantitative proteomics; colon; intestinal barrier; diet-induced obesity
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 2, 2024

2023 review

Progression to Obesity: Variations in Patterns of Metabolic Fluxes, Fat Accumulation, and Gastrointestinal Responses

[Review of ]. METABOLITES, 13(9).

By: F. Milhem n & S. Komarnytsky n 

author keywords: dietary obesity; weight gain; high-fat diet; lipid oxidation; metabolic inflexibility; metabolic rate; obesity-prone; obesity-resistant
TL;DR: Pattern of fat accumulation with a focus on visceral and ectopic adipose tissue, microbiome composition, and the immune status of the gastrointestinal tract have emerged as the most promising targets that allow personalization of obesity and warrant further investigations into the critical issue of a wider and long-term weight control. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 27, 2023

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