Fadia Jamal Milhem
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Works (3)
Updated: April 5th, 2024 18:16
2024 journal article
Biomarkers of Metabolic Adaptation to High Dietary Fats in a Mouse Model of Obesity Resistance
METABOLITES, 14(1).
author keywords: body composition; metabolic inflexibility; metabolic rate; dietary fats; skeletal muscle remodeling; glucose tolerance; microbiome
TL;DR:
It is shown that NR mice developed healthier fat/lean body mass ratios compared with the obesity-prone (super-responder, SR) phenotypes by upregulating gene expression networks that promote the accumulation of type 2a, fast-twitch, oxidative muscle tissues.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 26, 2024
2024 journal article
Obesity-Resistant Mice on a High-Fat Diet Display a Distinct Phenotype Linked to Enhanced Lipid Metabolism
NUTRIENTS, 16(1).
author keywords: dietary fats; energy substrate; body composition; metabolic rate; individual variability; personalized nutrition
TL;DR:
NR mice showed an increased ability to metabolize excessive dietary fats in skeletal muscle at the expense of reduced exercise capacity that persisted for the duration of the study, underscore the need for further comprehensive investigations into the mechanisms of obesity resistance.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 22, 2024
2023 review
Progression to Obesity: Variations in Patterns of Metabolic Fluxes, Fat Accumulation, and Gastrointestinal Responses
[Review of ]. METABOLITES, 13(9).
author keywords: dietary obesity; weight gain; high-fat diet; lipid oxidation; metabolic inflexibility; metabolic rate; obesity-prone; obesity-resistant
TL;DR:
Pattern of fat accumulation with a focus on visceral and ectopic adipose tissue, microbiome composition, and the immune status of the gastrointestinal tract have emerged as the most promising targets that allow personalization of obesity and warrant further investigations into the critical issue of a wider and long-term weight control.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 27, 2023
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