2022 journal article

Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure


By: G. Cheng n, D. Zhu n, K. Huang n & T. Caranasos*

MeSH headings : Animals; Exosomes; Heart Failure; Hydrogels / therapeutic use; Myocardial Infarction / drug therapy; Myocardium; Rats; Swine
TL;DR: An injectable ExoGel was created and tested by embedding mesenchymal stem cell (MSC) -derived exosomes into hyaluronic acid (HA) hydrogel and injected into the pericardial cavity of rats with transverse aortic constriction induced heart failure, which reduced LV chamber size and preserved wall thickness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 31, 2022

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