Eugene Eisen

Works (84)

Updated: August 15th, 2023 21:15

2010 journal article

Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 21(9), 848–855.

By: M. Ashwell n, R. Ceddia n, R. House n, J. Cassady n, E. Eisen n, T. Eling*, J. Collins*, S. Grissom*, J. Odle n 

Contributors: M. Ashwell n, R. Ceddia n, R. House n, J. Cassady n, E. Eisen n, T. Eling*, J. Collins*, S. Grissom*, J. Odle n 

author keywords: Gene expression; Mice; Liver, Conjugated linoleic acid; Obesity, Hepatic steatosis, Fatty liver
MeSH headings : Animals; Fatty Liver / genetics; Fatty Liver / metabolism; Gene Expression Profiling; Hepatocyte Nuclear Factor 4 / genetics; Linoleic Acids, Conjugated / pharmacology; Liver / metabolism; Male; Mice; Obesity / genetics; Obesity / metabolism
TL;DR: While surprisingly few genes in lipid metabolism were impacted, pathway analysis found that protein kinase A and cyclic adenosine monophosphate pathways signaling pathways were affected by CLA treatment and 98 of the 775 genes were found to be regulated by hepatocyte nuclear factor 4alpha, a transcription factor important in controlling liver metabolic status. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 article

Can we rescue an endangered species?

Eisen, E. J. (2008, February). JOURNAL OF ANIMAL BREEDING AND GENETICS, Vol. 125, pp. 1–2.

By: E. Eisen n

MeSH headings : Animals; Breeding; Genetics / education; Genetics / trends; United States; Workforce
Source: Web Of Science
Added: August 6, 2018

2007 article

Animal breeding: What does the future hold?

Eisen, E. J. (2007, March). ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, Vol. 20, pp. 453–460.

By: E. Eisen n

author keywords: animal breeding; selection; inbreeding; BLUP; quantitative trait loci; marker-assisted selection
TL;DR: Development of molecular genetic methods to search for quantitative trait loci provides the opportunity for incorporating marker-assisted selection and introgression as new tools for increasing efficiency of genetic improvement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Bayesian analyses of multiple epistatic QTL models for body weight and body composition in mice

GENETICS RESEARCH, 87(1), 45–60.

By: N. Yi *, D. Zinniel*, K. Kim *, E. Eisen n, A. Bartolucci *, D. Allison *, D. Pomp*

MeSH headings : Animals; Bayes Theorem; Body Composition / genetics; Body Weight / genetics; Epistasis, Genetic; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Models, Genetic; Quantitative Trait Loci
TL;DR: Bayesian analyses of multiple epistatic quantitative trait locus models for body weights at five ages and body composition traits in mice produced from a cross of the F1 revealed a temporally regulated network of multiple QTLs, suggesting that pleiotropy plays an important role in growth and obesity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Characterization of a line of pigs previously selected for increased litter size for RBP4 and follistatin

JOURNAL OF ANIMAL BREEDING AND GENETICS, 123(6), 389–395.

By: C. Blowe n, K. Boyette n, M. Ashwell n, E. Eisen n, O. Robison n & J. Cassady n

author keywords: follistatin; litter size; pigs; retinol-binding protein 4
MeSH headings : Animals; Female; Follistatin / genetics; Litter Size / genetics; Male; Polymerase Chain Reaction; Pregnancy; Receptors, Estrogen / genetics; Retinol-Binding Proteins / genetics; Sus scrofa / genetics; Sus scrofa / physiology
TL;DR: Responses to selection for increased litter size in pigs could not be attributed to effects at the ESR, RBP4 or FS loci. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice

EVOLUTION & DEVELOPMENT, 8(5), 468–476.

By: J. Wolf *, D. Pomp*, E. Eisen n, J. Cheverud* & L. Leamy*

MeSH headings : Animals; Body Size / genetics; Bone and Bones / anatomy & histology; Epistasis, Genetic; Extremities / anatomy & histology; Female; Genetic Variation; Inbreeding; Male; Mice; Mice, Inbred Strains; Multifactorial Inheritance; Organ Size / genetics; Quantitative Trait Loci; Regression Analysis
TL;DR: Although epistatic pleiotropy made a smaller contribution than single‐locus Pleiotropy, it clearly made a significant contribution to the genetic architecture of variation/covariation in a backcross population of mice created from the M16i and CAST/Ei strains. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Bayesian model selection for genome-wide epistatic quantitative trait loci analysis

GENETICS, 170(3), 1333–1344.

By: N. Yi *, B. Yandell *, G. Churchill *, D. Allison *, E. Eisen n & D. Pomp*

MeSH headings : Algorithms; Animals; Bayes Theorem; Chromosome Mapping / methods; Crosses, Genetic; Epistasis, Genetic; Inbreeding; Mice; Mice, Inbred Strains; Models, Genetic; Quantitative Trait Loci
TL;DR: A composite model space approach is used to develop a Bayesian model selection framework for identifying epistatic QTL for complex traits in experimental crosses from two inbred lines and a liberal constraint on the upper bound of the number of detectable QTL is placed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 review

Conjugated linoleic acid evokes de-lipidation through the regulation of genes controlling lipid metabolism in adipose and liver tissue

[Review of ]. OBESITY REVIEWS, 6(3), 247–258.

By: R. House n, J. Cassady n, E. Eisen n, M. McIntosh* & J. Odle n 

Contributors: R. House n, J. Cassady n, E. Eisen n, M. McIntosh* & J. Odle n 

author keywords: adipocyte; adipose tissue; CLA; de-lipidation; lipid metabolism; liver tissue; obesity
MeSH headings : Adipose Tissue / metabolism; Animals; Cattle; Energy Metabolism / drug effects; Gene Expression Regulation / drug effects; Humans; Linoleic Acids, Conjugated / pharmacology; Lipid Metabolism; Liver / metabolism; Mice; Obesity / genetics; Obesity / metabolism; Organ Size / drug effects; Rats
TL;DR: Recent advances and insights into conjugated linoleic acid's effects on obesity and lipid metabolism are examined, specifically focused on changes in gene expression and physiology of liver and adipose tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Fine mapping of a QTL region with large effects on growth and fatness on mouse chromosome 2

PHYSIOLOGICAL GENOMICS, 21(3), 411–422.

By: N. Jerez-Timaure *, E. Eisen n & D. Pomp*

author keywords: fine mapping; quantitative trait locus; obesity; congenic; recombinant progeny testing
MeSH headings : Animals; Body Composition / genetics; Body Weight / genetics; Chromosome Mapping; Crosses, Genetic; Female; Genotype; Growth / genetics; Male; Mice; Obesity / genetics; Phenotype; Quantitative Trait Loci; Recombination, Genetic
TL;DR: These efforts confirmed the presence of QTL with major effect on MMU2, narrowed the estimated region harboring the QTL from 38 to 12 cM, and further characterized phenotypic effects of theQTL, effectively culminating in a significantly decreased pool of positional candidate genes potentially representing these genes controlling predisposition to growth and fatness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Functional genomic characterization of delipidation elicited by trans-10, cis-12-conjugated linoleic acid (t10c12-CLA) in a polygenic obese line of mice

PHYSIOLOGICAL GENOMICS, 21(3), 351–361.

By: R. House n, J. Cassady n, E. Eisen n, T. Eling*, J. Collins*, S. Grissom*, J. Odle n 

Contributors: R. House n, J. Cassady n, E. Eisen n, T. Eling*, J. Collins*, S. Grissom*, J. Odle n 

author keywords: apoptosis; cell biology; gene expression; lipid metabolism; obesity
MeSH headings : Animals; Base Sequence; Body Weight / drug effects; DNA Primers; Gene Expression Regulation / drug effects; Genomics; Lipids / physiology; Male; Mice; Mice, Inbred ICR; Mice, Obese; Obesity / drug therapy; Obesity / genetics; Oligonucleotide Array Sequence Analysis; Organ Size / drug effects; Reverse Transcriptase Polymerase Chain Reaction; alpha-Linolenic Acid / analogs & derivatives; alpha-Linolenic Acid / therapeutic use
TL;DR: It was concluded that, in adipose tissue, CLA increased expression of uncoupling proteins (1 and 2), carnitine palmitoyltransferase system, tumor necrosis factor-alpha, and caspase-3 but decreased expression of peroxisome proliferator-activated receptor-gamma, glucose transporter-4, perilipin, caveolin-1, adiponectin, resistin, and Bcl-2. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Genomic mapping of direct and correlated responses to long-term selection for rapid growth rate in mice

Genetics, 170(4), 1863–1877.

By: M. Allan*, E. Eisen n & D. Pomp*

MeSH headings : Animals; Body Weight / genetics; Chromosome Mapping; Crosses, Genetic; Female; Genetic Markers; Genome; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Microsatellite Repeats; Quantitative Trait Loci; Quantitative Trait, Heritable; Selection, Genetic
TL;DR: Several QTL demonstrating differential regulation of regional adipose deposition and age-dependent regulation of growth and energy consumption were identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
7. Affordable and Clean Energy (OpenAlex)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: NC State University Libraries
Added: August 6, 2018

2005 book

The mouse in animal genetics and breeding research

By: E. Eisen*

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

A large-sample QTL study in mice: I. Growth

MAMMALIAN GENOME, 15(2), 83–99.

By: J. Rocha*, E. Eisen n, L. Van Vleck* & D. Pomp*

MeSH headings : Animals; Chromosome Mapping; Crosses, Genetic; Electrophoresis, Agar Gel; Mice; Mice, Inbred Strains / genetics; Mice, Inbred Strains / growth & development; Microsatellite Repeats / genetics; Models, Genetic; Multifactorial Inheritance / genetics; Phenotype; Quantitative Trait Loci / genetics
TL;DR: It is concluded that QTL analysis has reinforced classic polygenic paradigms put in place prior to molecular analysis and revealed large numbers of QTL for growth traits with an exponential distribution of magnitudes of effects and validated theoretical expectations regarding gene action. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

A large-sample QTL study in mice: II. Body composition

MAMMALIAN GENOME, 15(2), 100–113.

By: J. Rocha*, E. Eisen n, L. Van Vleck* & D. Pomp*

MeSH headings : Animals; Body Composition; Body Weights and Measures; Chromosome Mapping; Crosses, Genetic; Likelihood Functions; Male; Mice; Mice, Inbred Strains / genetics; Mice, Inbred Strains / growth & development; Mice, Inbred Strains / physiology; Multifactorial Inheritance / genetics; Quantitative Trait Loci / genetics; Regression Analysis
TL;DR: In this study, growth and body weight are interpreted in terms of organ subcomponents underlying the macro aggregate traits, and anchored on the corresponding genomic locations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

A large-sample QTL study in mice: III. Reproduction

MAMMALIAN GENOME, 15(11), 878–886.

By: J. Rocha*, E. Eisen n, F. Siewerdt n, L. Van Vleck* & D. Pomp*

MeSH headings : Animals; Chromosome Mapping; Female; Genetic Markers; Genitalia, Female / physiology; Likelihood Functions; Litter Size / genetics; Litter Size / physiology; Male; Mice; Ovulation / genetics; Ovulation / physiology; Pregnancy; Pregnancy Outcome / genetics; Quantitative Trait Loci
TL;DR: Using lines of mice having undergone long-term selection for high and low growth, a large-sample experiment was conducted to gain further understanding of the genetic architecture of complex polygenic traits, and some support for the relevance of QTL × genetic background interactions in reproduction was detected. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Ascorbic acid decreases heat shock protein 70 and plasma corticosterone response in broilers (Gallus gallus domesticus) subjected to cyclic heat stress

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 137(1), 35–42.

By: K. Mahmoud n, F. Edens n, E. Eisen n & G. Havenstein n

author keywords: hsp70; corticosterone; ascorbic acid; heat stress; broiler; oxidative stress
MeSH headings : Animals; Ascorbic Acid / blood; Ascorbic Acid / pharmacology; Chickens / blood; Chickens / physiology; Corticosterone / blood; HSP70 Heat-Shock Proteins / blood; HSP70 Heat-Shock Proteins / drug effects; Heat-Shock Response / physiology; Male; Myocardium / metabolism; Temperature
TL;DR: It was concluded that chickens experience a less severe stress response after exposure to high temperatures when they are provided dietary AA. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Characterization of QTL with major effects on fatness and growth on mouse chromosome 2

OBESITY RESEARCH, 12(9), 1408–1420.

By: N. Jerez-Timaure *, F. Kearney, E. Simpson*, E. Eisen n & D. Pomp*

author keywords: congenic line; body weight; predisposition; microarray; metabolomics
MeSH headings : Adipose Tissue; Alleles; Animals; Body Composition / genetics; Chromosome Mapping; Chromosomes, Mammalian; Diglycerides / chemistry; Eating; Fatty Acids / analysis; Female; Insulin / blood; Leptin / blood; Liver / chemistry; Male; Mice; Mice, Inbred C57BL; Phenotype; Quantitative Trait Loci / genetics; Triglycerides / chemistry; Weight Gain / genetics
TL;DR: Results confirm the presence and large effects of mouse chromosome 2 quantitative trait loci and further define their phenotypic consequences related to energy balance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

The M16 mouse: An outbred animal model of early onset polygenic obesity and diabesity

OBESITY RESEARCH, 12(9), 1397–1407.

By: M. Allan*, E. Eisen n & D. Pomp*

author keywords: adiposity; body weight; predisposition; insulin; glucose
MeSH headings : Animals; Blood Glucose / analysis; Body Composition; Body Temperature Regulation; Body Weight; Breeding; Diabetes Complications / genetics; Disease Models, Animal; Drinking; Eating; Female; Hyperphagia / genetics; Insulin / blood; Leptin / blood; Male; Mice; Mice, Inbred ICR; Obesity / complications; Obesity / genetics; Selection, Genetic
TL;DR: Phenotypes prevalent in the M16 model, with obesity and diabesity exhibited at a young age, closely mirror current trends in human populations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

The effect of dietary phosphorus on heat shock protein mRNAs during acute heat stress in male broiler chickens (Gallus gallus)

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 137(1), 11–18.

By: K. Mahmoud n, F. Edens n, E. Eisen n & G. Havenstein n

author keywords: heat shock protein; mRNA; phosphorus; broiler chicken; heat stress
MeSH headings : Animal Feed; Animals; Brain / metabolism; Chickens / metabolism; HSP70 Heat-Shock Proteins / biosynthesis; HSP70 Heat-Shock Proteins / genetics; HSP90 Heat-Shock Proteins / biosynthesis; HSP90 Heat-Shock Proteins / genetics; Heat Stress Disorders / metabolism; Liver / metabolism; Male; Myocardium / metabolism; Organ Specificity; Phosphorus, Dietary / pharmacology; RNA, Messenger / biosynthesis; Random Allocation; Spleen / metabolism; Temperature; Transcription, Genetic / drug effects
TL;DR: Although Pi+ did not show any significant increases in the expression of hSP mRNAs, there were consistently larger HSP mRNA values in liver and spleen tissues, which could be due to the involvement of hsp90 in steroid hormone receptors or the high metabolic activity of neurons in the central nervous system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Ionophores have limited effects on jejunal glucose absorption and energy metabolism in mice

Journal of Animal Science, 81(8), 2072–2079.

By: Y. Fan *, J. Croom n, E. Eisen n, H. Spires & L. Daniel n

MeSH headings : Animals; Biological Transport / drug effects; Dose-Response Relationship, Drug; Energy Metabolism / drug effects; Energy Metabolism / physiology; Glucose / pharmacokinetics; In Vitro Techniques; Intestinal Absorption / drug effects; Ionophores / pharmacology; Jejunum / drug effects; Jejunum / metabolism; Male; Mice; Monensin / analogs & derivatives; Monensin / pharmacology; Organ Size / drug effects; Oxygen Consumption / drug effects; Random Allocation
TL;DR: It is suggested that changes in the energetic requirements of animals treated with ionophores are not an issue in animal production and the efficiency of intestinal glucose absorption was not changed due to treatment in either trial. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Pleiotropy of quantitative trait loci for organ weights and limb bone lengths in mice

Physiological Genomics, 10(1), 21–29.

By: L. Leamy, D. Pomp, E. Eisen & J. Cheverud

MeSH headings : Animals; Bone and Bones / anatomy & histology; Chromosome Mapping; Crosses, Genetic; Extremities / anatomy & histology; Female; Genetic Markers / genetics; Genotype; Heart / anatomy & histology; Kidney / anatomy & histology; Liver / anatomy & histology; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Microsatellite Repeats / genetics; Organ Size / genetics; Phenotype; Quantitative Trait, Heritable; Spleen / anatomy & histology
Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

In ovo peptide YY administration improves body weight at hatch and day 3 in turkey poults

JOURNAL OF APPLIED POULTRY RESEARCH, 10(4), 380–384.

By: B. Coles n, J. Croom n, L. Daniel n, V. Christensen n & E. Eisen n

author keywords: peptide YY; in ovo; poult; body weight; feed conversion ratio
TL;DR: It is suggested that PYY enhances poult weight and may attenuate differences in BW caused by gender during early post-hatch life and in ovo administration of peptide YY at Day 18 of incubation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Inbred lines of mice derived from long-term growth selected lines: unique resources for mapping growth genes

MAMMALIAN GENOME, 12(9), 678–686.

By: L. Bunger*, A. Laidlaw*, G. Bulfield*, E. Eisen n, J. Medrano*, G. Bradford*, F. Pirchner*, U. Renne*, W. Schlote*, W. Hill*

MeSH headings : Animals; Body Weight; Chromosome Mapping; Crosses, Genetic; Eating; Female; Genetic Linkage; Growth / genetics; Male; Mice; Mice, Inbred Strains / growth & development; Quantitative Trait, Heritable; Selection, Genetic
TL;DR: Inbred extreme selected lines of mice selected for many generations for high or low growth in several laboratories around the world have been collected, and from these, inbred lines are being developed by recurrent full-sib mating in Edinburgh. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Segregation ratios and growth rate in inactive ovine metallothionein 1a-ovine growth hormone transgenic mice

Journal of Animal Science, 79(7), 1734–1741.

By: E. Eisen n & J. Murray*

MeSH headings : Animals; Female; Growth Hormone / blood; Growth Hormone / genetics; Homozygote; Least-Squares Analysis; Male; Metallothionein / genetics; Mice; Mice, Transgenic / growth & development; Sheep; Transgenes; Zinc / pharmacology
TL;DR: Reduced growth of oMt1a-oGH transgenic mice when the transgene is switched off suggests a subtle developmental abnormality, which may contribute to a reduction in fitness. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Correlated changes in fertility and fitness traits in lines of oMt1a-oGH transgenic mice selected for increased 8-week body weight

JOURNAL OF ANIMAL BREEDING AND GENETICS-ZEITSCHRIFT FUR TIERZUCHTUNG UND ZUCHTUNGSBIOLOGIE, 117(2), 83–95.

By: F. Siewerdt n, E. Eisen n & J. Murray*

TL;DR: The comparison of specific mating groups involving transgenic and nontransgenic mates revealed that the only consistent disadvantage in having a transgenic parent was the increase in the length of the cohabitation to littering interval. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Correlated responses to selection for large body size in oMt1a-oGH mice: growth, feed efficiency and body composition

JOURNAL OF ANIMAL BREEDING AND GENETICS, 117(6), 385–405.

By: K. Parks n, E. Eisen n & J. Murray*

TL;DR: Correlated responses were determined for growth, feed consumption, feed efficiency and body composition following short-term selection for large 8-week body weight in transgenic and nontransgenic mice to determine the utility of a transgene in improving a quantitative trait. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Correlated responses to selection for large body size in oMt1a-oGH transgenic mice: organ traits

GENETICS AND MOLECULAR BIOLOGY, 23(4), 771–780.

By: K. Parks n, E. Eisen n & J. Murray

TL;DR: Correlated responses of absolute weights of all organs in nontransgenic lines indicated moderately high genetic correlations of organ weights with body weight, but on a percentage of body weight basis, the correlated responses were much lower. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Correlated responses to selection for large body size in oMt1a-oGH transgenic mice: reproductive traits

GENETICAL RESEARCH, 75(2), 199–208.

By: K. Parks n, E. Eisen n, I. Parker n, L. Hester n & J. Murray*

MeSH headings : Animals; Body Weight; Female; Growth Hormone / genetics; Growth Hormone / physiology; Infertility, Female; Metallothionein / genetics; Metallothionein / physiology; Mice; Mice, Transgenic; Ovulation; Reproduction / physiology; Sheep
TL;DR: The low frequency of the transgene in the high-growth background TM line was associated with reduced fitness and a lower additive effect for 8-week body weight compared with the control background TC line, and the NC non-transgenic line did not exhibit reduced reproductive performance for these traits. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Peptide YY administration decreases brain aluminum in the Ts65Dn Down syndrome mouse model

Growth, Development, & Aging, 64(1-2), 3–19.

By: B. Berg, J. Croom, J. Fernandez, J. Spears, E. Eisen, I. Taylor, L. Daniel, B. Coles, F. Boeheim, P. Mannon

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Quantitative trait loci for directional but not fluctuating asymmetry of mandible characters in mice

GENETICAL RESEARCH, 76(1), 27–40.

By: L. Leamy*, D. Pomp*, E. Eisen n & J. Cheverud*

MeSH headings : Analysis of Variance; Animals; Genetic Variation; Lod Score; Mandible / embryology; Mandible / physiology; Mice; Mice, Inbred Strains; Microsatellite Repeats; Phenotype; Polymorphism, Restriction Fragment Length; Quantitative Trait, Heritable
TL;DR: Non-directional variation in right minus left differences in bilateral characters, referred to as fluctuating asymmetry (FA), often has been assumed to be largely or entirely environmental in origin, but three QTLs significantly affected DA in several characters, confirming both assumptions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Response to 13 generations of selection for increased 8-week body weight in lines of mice carrying a sheep growth hormone-based transgene

Journal of Animal Science, 78(4), 832–845.

By: F. Siewerdt n, E. Eisen n, J. Murray* & I. Parker n

MeSH headings : Animals; Female; Growth Hormone / genetics; Inbreeding; Least-Squares Analysis; Male; Mice; Mice, Transgenic / genetics; Sheep / genetics; Weight Gain / genetics
TL;DR: Evaluated selection in lines of transgenic mice suggest that constructs similar to the oMt1a-oGH, which allow tight regulation, may be successfully incorporated into commercial livestock and should have larger effects in populations that have not been subject to selection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

1999 chapter

Direct and correlated responses to short-term selection for 8-week body weight in lines of transgenic (oMt1a-oGH) mice

In G. B. A. J. D. Murray, A. M. Oberbauer, & M. M. McGloughlin (Eds.), Transgenic animals in agriculture. New York: CABI Publishing.

By: F. Siewerdt, E. Eisen & J. Murray

Ed(s): G. J. D. Murray, . A. M. Oberbauer & M. McGloughlin

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Factors influencing maternal behavior in the hubb/hubb mutant mouse

PHYSIOLOGY & BEHAVIOR, 68(1-2), 3–8.

By: B. Alston-Mills n, A. Parker n, E. Eisen n, R. Wilson n & S. Fletcher n

author keywords: dopamine; maternal behavior; mice; hubb/hubb; tyrosine hydroxylase
MeSH headings : 3,4-Dihydroxyphenylacetic Acid / metabolism; Animals; Brain Mapping; Cannibalism; Dopamine / physiology; Female; Lactation / physiology; Maternal Behavior / physiology; Median Eminence / anatomy & histology; Median Eminence / physiology; Mice; Mice, Inbred ICR; Mice, Neurologic Mutants; Pregnancy; Prolactin / metabolism; Tyrosine 3-Monooxygenase / physiology
TL;DR: Dopamine was similar in both strains at all stages, but DOPAC was significantly higher at early lactation in the mutants, and it is likely that the increase in DopAC in the mutant reflects a decrease in prolactin, which could contribute to the diminished maternal care in the mutations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Apparent energetic efficiency of jejunal glucose uptake in young adult turkeys selected for rapid growth

CANADIAN JOURNAL OF ANIMAL SCIENCE, 78(3), 301–306.

By: Y. Fan*, W. Croom*, V. Christensen*, A. Bird, L. Daniel*, B. McBride, E. Eisen*

author keywords: genetic selection; small intestine; glucose uptake; respiration; turkey
TL;DR: The data suggest selection for rapid growth in turkeys does not result in more efficient glucose uptake from the jejunum, and apparent energetic efficiency of glucose uptake is no difference between the lines. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice

METABOLISM-CLINICAL AND EXPERIMENTAL, 47(11), 1354–1359.

By: B. Black n, J. Croom n, E. Eisen n, A. Petro n, C. Edwards  n & R. Surwit n

MeSH headings : Animals; Body Composition; Dietary Fats / administration & dosage; Dietary Sucrose / administration & dosage; Intestines / enzymology; Male; Mice; Mice, Inbred C57BL; Species Specificity; Sucrase / metabolism; Weight Gain; alpha-Glucosidases / metabolism
TL;DR: The B6 mouse exhibits disproportionate weight gain and altered body composition on a high-fat diet, which coupled with the reduced body weight and increased body protein on a low-fat, high-sucrose diet suggests that factors-relative to fat metabolism rather than sucrose metabolism are responsible for obesity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Effects of zinc ion concentration on growth, fat content and reproduction in oMT1a-oGH transgenic mice

Growth, Development, & Aging, 62(4), 173–186.

By: E. Eisen, C. Peterson, I. Parker & J. Murray

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Gene action of the oMt1a-oGH transgene in two lines of mice with distinct selection backgrounds

JOURNAL OF ANIMAL BREEDING AND GENETICS-ZEITSCHRIFT FUR TIERZUCHTUNG UND ZUCHTUNGSBIOLOGIE, 115(3), 211–226.

By: F. Siewerdt n, E. Eisen n, J. Conrad-Brink & J. Murray*

TL;DR: Results indicate that incorporation of the oMt1a-oGH in populations of mice should be successful, and the transgene insert showed dominance effects on body, fat pads and organs weights. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Jejunal function and plasma amino acid concentrations in the segmental trisomic Ts65Dn mouse

Growth, Development, & Aging, 62(1-2), 47–59.

By: J. Cefalu, W. Croom, E. Eisen, E. Jones, L. Daniel & I. Taylor

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Effects of canola oil based high fat diets on growth, fat deposition and serum triglyceride and cholesterol levels in lines of mice selected for high and low fat percentage

Revista Brasileira De Genetica, 20(2), 203–213.

By: L. Benyon n, E. Eisen* & E. Jones*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Jejunal glucose uptake and oxygen consumption in turkey poults selected for rapid growth

POULTRY SCIENCE, 76(12), 1738–1745.

By: Y. Fan n, J. Croom n, V. Christensen n, B. Black n, A. Bird n, L. Daniel n, B. McBride n, E. Eisen n

author keywords: turkey; small intestine; glucose active transport; respiration; genetic selection
MeSH headings : Aging / metabolism; Aging / physiology; Animals; DNA / analysis; DNA / metabolism; Eating / physiology; Glucose / metabolism; Glucose / pharmacokinetics; Intestinal Absorption / physiology; Jejunum / metabolism; Jejunum / physiology; Oxygen Consumption / physiology; Random Allocation; Selection, Genetic; Time Factors; Turkeys / genetics; Turkeys / growth & development; Turkeys / physiology; Weight Gain / physiology
TL;DR: The data suggest that selection of turkeys for rapid growth at 16 wk of age did not increase efficiency of jejunal glucose uptake in 14-d-old turkey poults. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1996 journal article

Effect of trimethylamine-carbomethoxyborane on growth traits and lipid metabolism in lines of mice selected for high and low fat content

Growth (Menasha, Wis.), 60(1), 7.

By: E. Eisen, E. Jones, K. Rajendran & I. Hall

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

An ovine-growth-hormone transgene model suitable for selection experiments for growth in mice

JOURNAL OF ANIMAL BREEDING AND GENETICS, 112(5-6), 401–413.

By: E. Eisen n, J. Murray* & T. Schmitt n

TL;DR: When transgene expression is stimulated by exogenous zinc, growth rate is increased and there is no negative effect on female reproductive fitness when zinc supplement is discontinued, which makes this transgenic model suitable for selection studies involving growth. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1995 journal article

LONG-TERM RESTRICTED INDEX SELECTION IN MICE DESIGNED TO CHANGE FAT-CONTENT WITHOUT CHANGING BODY-SIZE

THEORETICAL AND APPLIED GENETICS, 91(2), 340–345.

By: E. Eisen n, L. Benyon n & J. Douglas n

author keywords: SELECTION INDEX; RESTRICTED INDEX; FAT; MICE
TL;DR: Low secondary selection differentials, caused by selecting within full-sib families, may have accounted for the failure of an intended restricted selection index to reduce epididymal fat pad weight (EF) without changing body weight (BW) in mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1993 journal article

EFFECT OF GENETIC BACKGROUND ON GROWTH OF MICE HEMIZYGOTIC FOR WILD-TYPE OR DWARF MUTATED BOVINE GROWTH-HORMONE TRANSGENES

THEORETICAL AND APPLIED GENETICS, 87(1-2), 161–169.

By: E. Eisen n, M. Fortman n, W. Chen* & J. Kopchick *

author keywords: GROWTH HORMONE; MICE; TRANSGENE; GROWTH
TL;DR: Results indicate that the effect of a GH transgene on growth can be affected both by a high-growth genetic background and the gender of progeny. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1993 journal article

MULTITRAIT RESTRICTED AND DESIRED GAINS SELECTION INDEXES DESIGNED TO CHANGE GROWTH AND BODY-COMPOSITION IN MICE

JOURNAL OF ANIMAL BREEDING AND GENETICS-ZEITSCHRIFT FUR TIERZUCHTUNG UND ZUCHTUNGSBIOLOGIE, 110(1), 13–29.

By: E. Eisen n

TL;DR: Effectiveness of restricted and desired gains index selection to change growth and body composition was tested in mice and correlated responses in component traits of the indices did not agree closely with expectation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1992 journal article

RESTRICTED SELECTION INDEX IN MICE DESIGNED TO CHANGE BODY-FAT WITHOUT CHANGING BODY-WEIGHT - CORRELATED RESPONSES

THEORETICAL AND APPLIED GENETICS, 84(3-4), 307–312.

By: E. Eisen n

author keywords: SELECTION INDEX; CORRELATED RESPONSES; FAT; FITNESS; MICE
TL;DR: Correlated responses to restricted index selection generally agreed with expectation when responses in component traits of the index were considered. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1992 journal article

Restricted index selection in mice designed to change body fat without changing body weight: direct responses

THEORETICAL AND APPLIED GENETICS, 83(8), 973–980.

By: E. Eisen n

author keywords: Mice; Fat; Selection index; Heritability; Genetic correlation
TL;DR: Replicated within full-sib family restricted index selection was conducted for eight generations in mice for high or low epididymal fat pad weight (EF) holding body weight (BW) constant, and the realized responses in component traits were decidedly asymmetric. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1990 journal article

Correlated responses in body composition based on selection for different indicator traits in mice

Journal of Animal Science, 68(11), 3557.

By: E. Eisen n & M. Coffey n

MeSH headings : Adipose Tissue / anatomy & histology; Animals; Body Composition / genetics; Body Weight / genetics; Breeding; Least-Squares Analysis; Male; Mice / genetics; Models, Biological; Phenotype
TL;DR: The results indicate that, although there are high positive genetic correlations between fat depots in mice, local control of lipogenesis and lipolysis exists at different sites of fat deposition, and the lack of correlated responses in fat-free percentage of protein (and percentage of ash) suggests that additive genetic variances are low for these traits and the genetic correlations with the selection criteria are low. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Replicate differences in lines of mice selected for body composition

Genome, 33(2), 294.

By: E. Eisen* & D. Pomp

MeSH headings : Adipose Tissue / anatomy & histology; Animals; Body Composition; Body Weight; Crosses, Genetic; Gene Frequency; Genetic Variation; Hybrid Vigor; Mice; Multivariate Analysis; Phenotype; Selection, Genetic; Statistics as Topic
TL;DR: Multivariate discriminant function and Mahalanobis distance analysis of selected traits showed that divergence between replicates within selection treatments was much less than among selection treatments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

1989 article

A RECESSIVE MUTATION CAUSING IMPERFORATE VAGINA IN MICE

JOURNAL OF HEREDITY, Vol. 80, pp. 478–482.

By: E. Eisen*, M. Hauser*, D. Pomp*, S. Anderson*, R. Newbold n & G. Mccormick

MeSH headings : Animals; Crosses, Genetic; Female; Genes, Recessive; Male; Mice; Mice, Mutant Strains / genetics; Phenotype; Random Allocation; Vaginal Diseases / genetics; Vaginal Diseases / pathology; Vaginal Diseases / veterinary
TL;DR: A recessive mutation (ipv) causing imperforate vagina was discovered in a line of mice selected for low lean tissue mass as a proportion of body weight, and two full sisters were found to have marked swelling of the perineum and complete closure of the vagina. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1989 journal article

Genetic models to predict crossbred performance: A review

Revista Brasileira De Genetica, 12(3), 13.

By: E. Eisen

Source: NC State University Libraries
Added: August 6, 2018

1989 review

SELECTION EXPERIMENTS FOR BODY-COMPOSITION IN MICE AND RATS - A REVIEW

[Review of ]. LIVESTOCK PRODUCTION SCIENCE, 23(1-2), 17–32.

By: E. Eisen n

TL;DR: Use of transgenic animals carrying genes coding for growth-promoting hormones, combined with artificial selection, offer additional strategies for changing body composition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1988 journal article

Estimates of genetic parameters and predicted selection responses for growth, fat and lean traits in mice

Journal of Animal Science, 66(5), 1153.

By: E. Eisen n & H. Prasetyo n

MeSH headings : Adipose Tissue / metabolism; Animals; Body Weight; Crosses, Genetic; Epididymis; Female; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains / growth & development; Phenotype; Selection, Genetic
TL;DR: Modified selection indexes were compared where responses in individual traits rather than the aggregate breeding value were of major importance and expected correlated responses in component traits were not influenced greatly over a widerange of ratios of economic weights, but in other cases the component traits changed sharply over a narrow range of ratios. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

Prenatal and postnatal correlated responses in maternal traits of mice assessed by crossfostering

Genetics, Selection, Evolution, 18(2), 145.

By: E. Eisen n & T. Bandy n

TL;DR: A crossfostering design was used to estimate correlated responses in prenatal genetic and postnatal maternal effects for maternal traits of mice, and selection for litter size at birth and 6-wk body weight resulted in large correlation responses in maternal traits. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1984 journal article

EFFECTS OF CONCURRENT LACTATION AND POSTPARTUM MATING ON REPRODUCTIVE-PERFORMANCE IN MICE SELECTED FOR LARGE LITTER SIZE

JOURNAL OF ANIMAL SCIENCE, 59(5), 1224–1238.

By: E. Eisen n & A. Saxton n

MeSH headings : Animals; Female; Lactation; Litter Size; Mice; Mice, Inbred Strains / genetics; Mice, Inbred Strains / physiology; Mortality; Pregnancy; Reproduction; Selection, Genetic; Sexual Behavior, Animal; Weaning
TL;DR: If the differences in the first two litters reflect subsequent parities, lifetime reproductive performance in the PP environment would be reduced in the high fecundity line, which appears to depend upon the environment of selection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1984 journal article

ESTIMATING BODY-COMPOSITION IN MICE BY NEAR-INFRARED SPECTROPHOTOMETRY

JOURNAL OF ANIMAL SCIENCE, 58(5), 1181–1190.

By: E. Eisen n, T. Bandy n, W. Mcclure n & G. Horstgenschwark n

UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1984 journal article

POSTPARTUM PERFORMANCE IN A DIALLEL CROSS AMONG LINES OF MICE SELECTED FOR LITTER SIZE AND BODY-WEIGHT

JOURNAL OF ANIMAL SCIENCE, 58(4), 863–877.

By: E. Eisen n, G. Horstgenschwark n, T. Bandy n & A. Saxton n

MeSH headings : Animals; Body Weight; Crosses, Genetic; Female; Hybrid Vigor; Lactation; Litter Size; Male; Mice / genetics; Mice / physiology; Models, Genetic; Pregnancy; Selection, Genetic
TL;DR: Postpartum dam performance was studied in a complete diallel design involving five lines of mice, indicating important pleiotropic effects in average direct genetic and average maternal genetic effects for dam body weight and litter size at parturition persisted throughout lactation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1983 journal article

GENETIC INTERPRETATION AND ANALYSIS OF DIALLEL CROSSES WITH ANIMALS

THEORETICAL AND APPLIED GENETICS, 65(1), 17–23.

By: E. Eisen n, G. Horstgenschwark n, A. Saxton  n & T. Bandy n

TL;DR: A genetic framework was developed for the interpretation of statistical parameters estimated from a diallel experiment among a fixed set of lines, based on direct and maternal additive and dominance genetic effects as would be expected in animal species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1983 journal article

GENOTYPE BY ENVIRONMENT INTERACTIONS AND GENETIC CORRELATIONS INVOLVING 2 ENVIRONMENTAL-FACTORS

THEORETICAL AND APPLIED GENETICS, 67(1), 75–86.

By: E. Eisen n & A. Saxton  n

TL;DR: Paternal half-sib and factorial mating designs were used to obtain the various genetic correlations and Correction factors for the interaction variances were also derived. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1981 journal article

Correlated responses in male reproductive traits in mice selected for litter size and body weight

Genetics, 99(3), 513.

By: E. Eisen & B. Johnson

Source: NC State University Libraries
Added: August 6, 2018

1981 journal article

Predicting selection response for total litter weight

Journal of Animal Breeding and Genetics, 98(1), 54.

By: E. Eisen n

Source: NC State University Libraries
Added: August 6, 2018

1980 journal article

Conclusions from long-term selection experiments with mice

Journal of Animal Breeding and Genetics, 97(4), 305.

By: E. Eisen n

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

1980 journal article

EFFECT OF LITTER SIZE AT BIRTH ON LACTATION IN MICE

JOURNAL OF ANIMAL SCIENCE, 50(4), 680–688.

By: E. Eisen n, J. Nagai n, H. Bakker n & J. Hayes n

MeSH headings : Animals; Animals, Newborn / growth & development; Body Weight; Female; Lactation; Litter Size; Mice / growth & development; Pregnancy
TL;DR: The data provide no evidence to support the hypothesis that increased fetal number or mass results in a greater lactational output by the dam, and multiple regression analyses indicated that dam body weight at parturition consistently accounted for more of the variation in 12-day litter weight than litter size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1980 journal article

EFFECTS OF MATERNAL ENVIRONMENT AND SELECTION FOR LITTER SIZE AND BODY-WEIGHT ON BIOMASS AND FEED-EFFICIENCY IN MICE

JOURNAL OF ANIMAL SCIENCE, 50(4), 664–679.

By: E. Eisen n & B. Durrant  n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1980 journal article

Effects of parity on reproductive performance in lines of mice selected for litter size or body weight

Revista Brasileira De Genetica, 3(1), 1.

By: E. Eisen & B. Durrant

Source: NC State University Libraries
Added: August 6, 2018

1980 journal article

GENETIC AND MATERNAL ENVIRONMENTAL-FACTORS INFLUENCING LITTER SIZE AND REPRODUCTIVE EFFICIENCY IN MICE

JOURNAL OF ANIMAL SCIENCE, 50(3), 428–441.

By: E. Eisen n & B. Durrant  n

MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Body Weight; Female; Litter Size; Male; Mice / genetics; Mice / growth & development; Mice / physiology; Postnatal Care / veterinary; Pregnancy; Reproduction
TL;DR: The established genetic differences in litter size among lines due to selection were considerably larger than the maternal environmental effect due to postnatal litter size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1980 journal article

INFLUENCE OF EARLY-PREGNANCY ON REPRODUCTIVE RATE IN LINES OF MICE SELECTED FOR LITTER SIZE

THEORETICAL AND APPLIED GENETICS, 57(5), 209–220.

By: E. Eisen n

TL;DR: The influence of male-induced early puberty on female reproductive rate was determined in three lines of mice differing in litter size and body weight, suggesting that the physiological state of the very young female was not optimum for normal pregnancy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1979 journal article

EFFECTS OF PREGNANCY AND MATING AGE ON PROTEIN AND FAT DEPOSITION IN POLYGENIC OBESE MICE

JOURNAL OF ANIMAL SCIENCE, 48(4), 810–822.

By: E. Eisen n & J. Leatherwood n

MeSH headings : Adipose Tissue / metabolism; Age Factors; Animals; Body Composition; Body Weight; Female; Mice; Obesity / metabolism; Pregnancy; Pregnancy, Animal; Proteins / metabolism
TL;DR: Effects of pregnancy and mating age on rate (gain/day) and efficiency ( gain/feed) ofLean and fat deposition were determined in the M 16 line of mice selected for rapid postweaning weight gain and related responses in M16 mice included increased lean and fat gain and efficiency. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1978 journal article

Cellular characteristics of gonadal fat pads, livers and kidneys in two strains of mice selected for rapid growth

Growth (Menasha, Wis.), 42(1), 7.

By: E. Eisen, J. Hayes, C. Allen, H. Bakker & J. Nagai

Source: NC State University Libraries
Added: August 6, 2018

1978 journal article

Single-trait and antagonistic index selection for litter size and body weight in mice

Genetics, 88(4), 781.

By: E. Eisen

Source: NC State University Libraries
Added: August 6, 2018

1977 journal article

BODY-COMPOSITION AND ENERGETIC EFFICIENCY IN 2 LINES OF MICE SELECTED FOR RAPID GROWTH-RATE AND THEIR F1 CROSSES

THEORETICAL AND APPLIED GENETICS, 49(1), 21–34.

By: E. Eisen n, H. Bakker n & J. Nagai n

TL;DR: Partitioning of correlated response differences between M16 and H6 into average direct and average maternal genetic effects indicated that average direct genetic effects, favoring M16, were responsible for the major difference between the selected populations. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1977 journal article

CORRELATED RESPONSES IN GROWTH AND BODY-COMPOSITION OF REPLICATED SINGLE-TRAIT AND INDEX SELECTED LINES OF MICE

THEORETICAL AND APPLIED GENETICS, 49(3), 133–144.

By: E. Eisen n & T. Bandy n

TL;DR: In agreement with theory, antagonistic index selection generally yielded smaller genetic responses than single trait selection in lines of mice selected in the following ways: W+Tio, increased six-week body weight (WT6); W ° Ti+, increasedSix-week tail length (TL6); W+Ti−, increased WT6 and decreased TL6; W−Ti+, decreased WT7; M16, increased three-to six- weeks postweaning gain (PWG); and (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1977 journal article

Effects of early pregnancy on postnatal maternal performance of mice

Animal Production, 25(1), 1.

By: E. Eisen n, W. Williams n & J. Hayes n

Source: NC State University Libraries
Added: August 6, 2018

1977 journal article

Effects of early pregnancy on reproduction, growth and feed efficiency of polygenic obese mice

Growth (Menasha, Wis.), 41(4), 263.

By: E. Eisen

Source: NC State University Libraries
Added: August 6, 2018

1977 journal article

RESTRICTED SELECTION INDEX - APPROACH TO SELECTING FOR FEED-EFFICIENCY

JOURNAL OF ANIMAL SCIENCE, 44(6), 958–972.

By: E. Eisen n

Source: Web Of Science
Added: August 6, 2018

1976 journal article

EFFECTS OF EARLY-PREGNANCY IN GROWTH, BODY COMPOSITION AND EFFICIENCY IN MICE

JOURNAL OF ANIMAL SCIENCE, 42(1), 52–62.

By: E. Eisen n & J. Leatherwood n

MeSH headings : Age Factors; Animal Feed; Animals; Body Composition; Female; Labor, Obstetric; Lipids / analysis; Mice / growth & development; Mice / metabolism; Mice / physiology; Minerals / analysis; Pregnancy; Pregnancy, Animal; Proteins / analysis
Source: Web Of Science
Added: August 6, 2018

1976 journal article

Results of growth curve analyses in mice and rats

Journal of Animal Science, 42(4), 1008.

By: E. Eisen n

MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Female; Food Deprivation; Genetic Variation; Genotype; Hyperplasia; Hypertrophy; Lactation; Male; Mice / growth & development; Muscle Development; Pregnancy; Rats / growth & development; Selection, Genetic; Weaning
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

1975 journal article

INFLUENCE OF MALES PRESENCE ON SEXUAL-MATURATION, GROWTH AND FEED EFFICIENCY OF FEMALE MICE

JOURNAL OF ANIMAL SCIENCE, 40(5), 816–825.

By: E. Eisen n

Source: Web Of Science
Added: August 6, 2018

1975 journal article

Population size and selection intensity effects on long-term selection response in mice

Genetics, 79(2), 305.

By: E. Eisen

Source: NC State University Libraries
Added: August 6, 2018

1974 journal article

GENETIC DRIFT AND INBREEDING DEPRESSION MEASURED FROM CONTROL POPULATIONS OF MICE

CANADIAN JOURNAL OF GENETICS AND CYTOLOGY, 16(1), 91–104.

By: E. Eisen* & J. Hanrahan

MeSH headings : Animals; Animals, Newborn; Birth Weight; Body Weight; Environment; Extrachromosomal Inheritance; Female; Fertility; Gene Frequency; Genetic Variation; Inbreeding; Male; Mice; Mice, Inbred ICR; Pedigree; Phenotype; Selection, Genetic
TL;DR: Analysis of generation trends in the WK6 variance components of the ICR stock showed no significant changes in heritability, total maternal effects or env... (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1973 journal article

Direct and maternal genetic responses resulting from selection for 12-day litter weight in mice

Canadian Journal of Genetics and Cytology, 15(3), 483.

By: E. Eisen

MeSH headings : Age Factors; Analysis of Variance; Animals; Body Weight; Crosses, Genetic; Female; Growth; Hybrid Vigor; Hybridization, Genetic; Lactation; Male; Mice; Models, Biological; Pregnancy; Pregnancy, Animal; Selection, Genetic; Sex Factors
TL;DR: Response to selection for 12-day litter weight in mice was evaluated in terms of average direct and average maternal genetic responses, with respect to selected and control parental responses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

1973 journal article

Effects of population size and selection intensity on correlated responses to selection for postweaning gain in mice

Genetics, 74(1), 157.

By: E. Eisen, J. Hanrahan & J. Legates

Source: NC State University Libraries
Added: August 6, 2018

1973 journal article

GENETIC AND PHENOTYPIC FACTORS INFLUENCING SEXUAL MATURATION OF FEMALE MICE

JOURNAL OF ANIMAL SCIENCE, 37(5), 1104–1111.

By: E. Eisen n

MeSH headings : Age Factors; Animals; Birth Weight; Body Weight; Female; Housing, Animal; Male; Maternal Behavior; Mice / physiology; Phenotype; Reproduction; Sex Factors; Vagina / physiology; Weaning
Source: Web Of Science
Added: August 6, 2018

1973 journal article

Genetic drift and inbreeding depression in quantitative traits of mice

Genetics, 74(2), 70.

By: E. Eisen & J. Hanrahan

Source: NC State University Libraries
Added: August 6, 2018

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