Works (28)

Updated: August 18th, 2023 05:01

2023 journal article

Protective Effects of Polyphenol-Rich Extracts against Neurotoxicity Elicited by Paraquat or Rotenone in Cellular Models of Parkinson's Disease

ANTIOXIDANTS, 12(7).

By: M. Tambe*, A. Jacquet*, K. Strathearn*, J. Hensel*, B. Colon*, A. Chandran*, G. Yousef n, M. Grace n ...

author keywords: anthocyanin; Nrf2; paraquat; Parkinson's disease; polyphenols; rotenone
TL;DR: It is suggested that extracts enriched with certain combinations of ANC, PAC, stilbenes, and other polyphenols could potentially slow neurodegeneration in the brains of individuals exposed to PQ or rotenone by activating cellular antioxidant mechanisms and/or alleviating mitochondrial dysfunction. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 25, 2023

2019 journal article

Variation in anthocyanin profiles of 27 genotypes of red cabbage over two growing seasons

FOOD CHEMISTRY, 301.

By: R. Strauch n, M. Mengist n, K. Pan n, G. Yousef n, M. Iorizzo n, A. Brown n, M. Lila n

author keywords: Red cabbage; Acylated anthocyanin; Breeding population; HPLC-DAD-MSE
MeSH headings : Acylation; Anthocyanins / analysis; Anthocyanins / chemistry; Brassica / chemistry; Brassica / genetics; Brassica / metabolism; Chromatography, High Pressure Liquid; Genotype; Mass Spectrometry; Plant Breeding; Polymorphism, Genetic; Seasons
TL;DR: PCA analysis identified anthocyanin accumulation traits and genotypes with high diversity which can be utilized in future investigations into the genetic and molecular basis for anthochenin production, acylation, and diversity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 23, 2019

2017 journal article

Development, and genetic and metabolic characterization of new tomato mutants with enhanced and deficient carotenoid content

JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY, 92(5), 475–483.

By: Y. Dan*, G. Yousef n, F. Campbell*, D. Phelps*, C. Burnett*, A. Kekkonen*, A. Shockley*, M. Lila n

author keywords: Carotenoid; lycopene; -carotene; Solanum lycopersicum; mutagenesis
TL;DR: Genetic and metabolic analyses showed that new mutants with enhanced and deficient carotenoid content in a single genetic background of tomato cv. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Inter- and intra-seasonal changes in anthocyanin accumulation and global metabolite profiling of six blueberry genotypes

JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 59, 105–110.

By: M. Timmers n, M. Grace n, G. Yousef n & M. Lila n

Contributors: M. Timmers n, M. Grace n, G. Yousef n & M. Lila n

author keywords: Anthocyanin; HPLC; PCA; Blueberry; Metabolite profile; Genotype and seasonal variations; Food analysis; Food composition
TL;DR: Genotypes were easily distinguished from one another across each harvest season, indicating that each genotype had distinctly different metabolite profile, whereas each of the rabbiteye genotypes overlapped on the scores plot, indicating commonalities in metabolite profiles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Chemical composition, antioxidant and anti-inflammatory properties of pistachio hull extracts

Food Chemistry, 210, 85–95.

By: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

Contributors: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

author keywords: Anacardic acids; Triterpene acids; Carotenoids; Tocopherols; Polyphenols; Anti-inflammatory
MeSH headings : Animals; Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / isolation & purification; Anti-Inflammatory Agents / pharmacology; Antioxidants / chemistry; Antioxidants / isolation & purification; Antioxidants / pharmacology; Cell Line; Dose-Response Relationship, Drug; Macrophages / drug effects; Macrophages / metabolism; Mice; Pistacia; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Plant Extracts / pharmacology; Reactive Oxygen Species / antagonists & inhibitors; Reactive Oxygen Species / metabolism
TL;DR: The P extract significantly decreased the non-mitochondrial oxidative burst associated with inflammatory response in macrophages and significantly inhibited the release of nitric oxide and reactive oxygen species in lipopolysaccharide-stimulated RAW 264.7 macrophage cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

In vitro lipolytic, antioxidant and anti-inflammatory activities of roasted pistachio kernel and skin constituents

Food & Function, 7(10), 4285–4298.

By: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

Contributors: M. Grace n, D. Esposito n, M. Timmers n, J. Xiong n, G. Yousef n, S. Komarnytsky n, M. Lila n

MeSH headings : Animals; Antioxidants; Cell Survival / drug effects; Cooking; Macrophages / drug effects; Macrophages / metabolism; Mice; Phytochemicals; Pistacia / chemistry; RAW 264.7 Cells; Reactive Oxygen Species; Respiratory Burst; Seeds / chemistry
TL;DR: The SNP had the strongest effect in decreasing non-mitochondrial oxidative burst associated with inflammatory response in macrophages, and was the most potent to inhibit the expression of COX2. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

A high-throughput, simultaneous analysis of carotenoids, chlorophylls and tocopherol using sub two micron core shell technology columns

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1001, 41–48.

By: K. Chebrolu, G. Yousef, R. Park, Y. Tanimura & A. Brown

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Anthocyanin, carotenoid, tocopherol, and ellagitannin content of red raspberry cultivars grown under field or high tunnel cultivation in the Southeastern United States

Journal of the American Society for Horticultural Science, 140(2), 163–171.

By: C. Bradish, G. Yousef, G. Ma, P. Perkins-Veazie & G. Fernandez

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Genetic analysis of glucosinolate variability in broccoli florets using genome-anchored single nucleotide polymorphisms

Theoretical and Applied Genetics, 128(7), 1431–1447.

By: A. Brown, G. Yousef, R. Reid, K. Chebrolu, A. Thomas, C. Krueger, E. Jeffery, E. Jackson, J. Juvik

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Anthocyanin profiling of wild maqui berries (Aristotelia chilensis [Mol.] Stuntz) from different geographical regions in Chile

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 94(13), 2639–2648.

By: C. Fredes*, G. Yousef n, P. Robert*, M. Grace n, M. Lila n, M. Gomez*, M. Gebauer*, G. Montenegro*

Contributors: C. Fredes*, G. Yousef n, P. Robert*, M. Grace n, M. Lila n, M. Gómez*, M. Gebauer*, G. Montenegro*

author keywords: delphinidin-3; 5-diglucoside; delphinidin-3-glucoside; genetic diversity; maqui genotypes; ISSR-PCR
MeSH headings : Altitude; Anthocyanins / analysis; Anthocyanins / metabolism; Antioxidants / analysis; Antioxidants / metabolism; Chile; Chromatography, High Pressure Liquid; Climate; Elaeocarpaceae / chemistry; Elaeocarpaceae / genetics; Elaeocarpaceae / growth & development; Elaeocarpaceae / metabolism; Fruit / chemistry; Fruit / genetics; Fruit / growth & development; Fruit / metabolism; Genetic Markers; Genetic Variation; Limit of Detection; Phenols / analysis; Phenols / metabolism; Phylogeny; Spatio-Temporal Analysis; Species Specificity; Spectrometry, Mass, Electrospray Ionization; Wilderness
TL;DR: Three maqui genotypes exhibited significantly higher anthocyanin content than the others, as measured by pH differential method and high-performance liquid chromatography-mass spectrometry and significant genetic diversity was noted within each ecological population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Bioactive Capacity, Sensory Properties, and Nutritional Analysis of a Shelf Stable Protein-rich Functional Ingredient with Concentrated Fruit and Vegetable Phytoactives

PLANT FOODS FOR HUMAN NUTRITION, 69(4), 372–378.

By: M. Grace n, G. Yousef n, D. Esposito n, I. Raskin* & M. Lila n

Contributors: M. Grace n, G. Yousef n, D. Esposito n, I. Raskin* & M. Lila n

author keywords: Muscadine; Kale; Protein isolate; Inflammatory biomarkers
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use; Brassica / chemistry; Cannabis; Carotenoids / pharmacology; Carotenoids / therapeutic use; Chemokine CCL2 / metabolism; Diet; Dietary Proteins / analysis; Fruit / chemistry; Functional Food / analysis; Glucosinolates / pharmacokinetics; Glucosinolates / pharmacology; Humans; Inflammation / drug therapy; Inflammation / metabolism; Interleukin-6 / metabolism; Mice; Nutritive Value; Plant Preparations / pharmacology; Plant Preparations / therapeutic use; Polyphenols / pharmacology; Polyphenols / therapeutic use; Soybean Proteins; Taste; Vegetables / chemistry; Vitis / chemistry
TL;DR: Proximate analyses determined that fortification of the soy protein isolate with muscadine or kale bioactives resulted in elevated dietary fibers, total carbohydrates, and free sugars, but did not increase calories/100 g dry matrix compared to unfortified SPI. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Concentrating Immunoprotective Phytoactive Compounds from Fruits and Vegetables into Shelf-stable Protein-rich Ingredients

PLANT FOODS FOR HUMAN NUTRITION, 69(4), 317–324.

By: G. Yousef n, M. Grace n, J. Medina n, S. Neff n, I. Guzman n, A. Brown n, I. Raskin*, M. Lila n

Contributors: G. Yousef n, M. Grace n, J. Medina n, S. Neff n, I. Guzman n, A. Brown n, I. Raskin*, M. Lila n

author keywords: Muscadine; Kale; Polyphenolics; Carotenoids; Glucosinolates; Protein isolate
MeSH headings : Brassica / chemistry; Carotenoids / analysis; Diet; Dietary Proteins; Food Handling; Fruit / chemistry; Functional Food; Glucosinolates / analysis; Humans; Immunologic Factors; Plant Extracts / chemistry; Polyphenols / analysis; Vegetables / chemistry; Vitis / chemistry
TL;DR: Neither total phenolics nor glucosinolates were significantly diminished even after long term storage at 4, 20, or 37 °C, whereas carotenoids degraded over time, particularly at higher temperatures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

High-density single nucleotide polymorphism (SNP) array mapping in Brassica oleracea: identification of QTL associated with carotenoid variation in broccoli florets

Theoretical and Applied Genetics, 127(9), 2051–2064.

By: A. Brown, G. Yousef, K. Chebrolu, R. Byrd, K. Everhart, A. Thomas, R. Reid, I. Parkin ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Impact of interspecific introgression on anthocyanin profiles of Southern Highbush blueberry

Journal of the American Society for Horticultural Science, 139(2), 99–112.

By: G. Yousef, M. Lila, I. Guzman, J. Ballington & A. Brown

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease

Brain Research, 1555, 60–77.

By: K. Strathearn*, G. Yousef n, M. Grace n, S. Roy*, M. Tambe*, M. Ferruzzi*, Q. Wu*, J. Simon* ...

Contributors: K. Strathearn*, G. Yousef n, M. Grace n, S. Roy*, M. Tambe*, M. Ferruzzi*, Q. Wu*, J. Simon*, M. Lila n, J. Rochet*

author keywords: Anthocyanin; Microglial activation; Mitochondria; Parkinson's disease; Proanthocyanidin; Rotenone
MeSH headings : Animals; Anthocyanins / therapeutic use; Cells, Cultured; Dopaminergic Neurons / drug effects; Dopaminergic Neurons / metabolism; Mice; Microglia / drug effects; Mitochondria / drug effects; Mitochondria / metabolism; Neuroprotective Agents / therapeutic use; Parkinson Disease / drug therapy; Parkinson Disease / metabolism; Phytotherapy; Plant Extracts / therapeutic use; Proanthocyanidins / therapeutic use; Rotenone / toxicity; Tyrosine 3-Monooxygenase / metabolism
TL;DR: It is suggested that anthocyanin- and proanthocyanidin-rich botanical extracts may alleviate neurodegeneration in PD via enhancement of mitochondrial function. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Novel strategies for capturing health-protective mango phytochemicals in shelf stable food matrices

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, 66(2), 175–185.

By: I. Guzman n, M. Grace n, G. Yousef n, I. Raskin* & M. Lila n

Contributors: I. Guzman n, M. Grace n, G. Yousef n, I. Raskin* & M. Lila n

author keywords: Carotenoids; fortified foods; polyphenols; protein-rich flour; vitamin A
MeSH headings : Africa; Arachis; Carbohydrates / analysis; Carotenoids / administration & dosage; Carotenoids / analysis; Diet; Dietary Proteins; Flour / analysis; Food Handling / methods; Food Preservation; Fruit / chemistry; Health; Helianthus; Humans; Malnutrition / prevention & control; Mangifera / chemistry; Phytochemicals / analysis; Plant Oils; Polyphenols / administration & dosage; Polyphenols / analysis; Rural Population; Soybeans; Sunflower Oil
TL;DR: Cost-effective methods for concentration and stabilization of otherwise perishable mango fruit phytoactives into shelf stable high protein ingredients were developed to combat stunting (malnutrition) in rural Africa and capture the benefits of Otherwise perishable seasonal resources by complexing healthful proteins together with phy toactive compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2014 article

Stressed for Success: How the Berry's Wild Origins Result in Multifaceted Health Protections

X INTERNATIONAL SYMPOSIUM ON VACCINIUM AND OTHER SUPERFRUITS, Vol. 1017, pp. 23–43.

By: M. Lila*, J. Kellogg*, M. Grace*, G. Yousef*, T. Kraft & R. Rogers

author keywords: elicitation; anthocyanins; proanthocyanidins; inflammation; metabolic syndrome
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Variation of carotenoids and polyphenolics in peach and implications on breeding for modified phytochemical profiles

Journal of the American Society for Horticultural Science, 139(6), 676–686.

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Anthocyanins and proanthocyanidins from blueberry-blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate-utilizing enzymes in vitro

MOLECULAR NUTRITION & FOOD RESEARCH, 57(7), 1182–1197.

By: M. Johnson*, E. Mejia*, J. Fan*, M. Lila n & G. Yousef n

author keywords: Anthocyanin; Berry; Diabetes; Hydrolysable tannins; Inflammation; Proanthocyanidin
MeSH headings : Animals; Anthocyanins / analysis; Anthocyanins / pharmacology; Antioxidants / pharmacology; Beverages; Blueberry Plants / chemistry; Cell Line, Tumor; Cell Proliferation / drug effects; Fermentation; Fruit / chemistry; Glucosides / analysis; Inflammation / prevention & control; Lipopolysaccharides / adverse effects; Macrophages / drug effects; Macrophages / metabolism; Mice; NF-kappa B / genetics; NF-kappa B / metabolism; Plant Extracts / pharmacology; Polyphenols / pharmacology; Proanthocyanidins / pharmacology; Wine / analysis; alpha-Amylases / metabolism; alpha-Glucosidases / metabolism
TL;DR: ANCs demonstrated that delphinidin-3-arabinoside effectively inactivated dipeptidyl peptidase-IV by binding with the lowest interaction energy (-3228 kcal/mol). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Berry and citrus phenolic compounds inhibit dipeptidyl peptidase IV: Implications in diabetes management

Evidence-Based Complementary and Alternative Medicine.

By: J. Fan, M. Johnson, M. Lila, G. Yousef & E. Mejia

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Efficient Quantification of the Health-Relevant Anthocyanin and Phenolic Acid Profiles in Commercial Cultivars and Breeding Selections of Blueberries (Vaccinium spp.)

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61(20), 4806–4815.

Contributors: G. Yousef n, A. Brown n, Y. Funakoshi n, F. Mbeunkui n, M. Grace n, J. Ballington n, A. Loraine*, M. Lila n

author keywords: anthocyanins; chlorogenic acid; blueberry; HPLC-DAD-MS; Vaccinium spp.; freeze-drying; health benefits
MeSH headings : Anthocyanins / analysis; Blueberry Plants / chemistry; Breeding; Chromatography, High Pressure Liquid / methods; Food, Preserved / analysis; Frozen Foods / analysis; Fruit / chemistry; Genotype; Glucosides / analysis; Health Promotion; Humans; Hydroxybenzoates / analysis; Plant Extracts / chemistry; Species Specificity; Tandem Mass Spectrometry / methods
TL;DR: An improved protocol was developed for the accurate, efficient, and rapid comparative screening for large blueberry sample sets and different genotypes frequently had comparable overall levels of total anthocyanins and phenolic acids, but differed dramatically in individual profiles of compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Phytochemical changes in phenolics, anthocyanins, ascorbic acid, and carotenoids associated with sweetpotato storage and impacts on bioactive properties

FOOD CHEMISTRY, 145, 717–724.

By: M. Grace n, G. Yousef n, S. Gustafson n, V. Truong n, G. Yencho n & M. Lila n

Contributors: M. Grace n, G. Yousef n, S. Gustafson n, V. Truong n, G. Yencho n & M. Lila n

author keywords: Sweetpotato; Phenolics; Carotenoids; Antioxidant activity; Storage; Postharvest
MeSH headings : Anthocyanins / analysis; Anthocyanins / isolation & purification; Anti-Inflammatory Agents / chemistry; Anti-Inflammatory Agents / isolation & purification; Antioxidants / chemistry; Antioxidants / isolation & purification; Ascorbic Acid / analysis; Ascorbic Acid / isolation & purification; Carotenoids / analysis; Carotenoids / isolation & purification; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Food Storage; Genotype; Humans; Ipomoea batatas / chemistry; Ipomoea batatas / genetics; Ipomoea batatas / metabolism; Lipopolysaccharides; Phenols / analysis; Phenols / isolation & purification; Plant Extracts / chemistry; Reactive Oxygen Species / metabolism; Temperature; Time Factors
TL;DR: Gradual changes in sweetpotato phytochemical content and antioxidant and anti-inflammatory capacity were noted during normal long-term storage, but the specific effects were genotype-dependent. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Comparison of Health-Relevant Flavonoids in Commonly Consumed Cranberry Products

JOURNAL OF FOOD SCIENCE, 77(8), H176–H183.

By: M. Grace n, A. Massey n, F. Mbeunkui n, G. Yousef n & M. Lila n

Contributors: M. Grace n, A. Massey n, F. Mbeunkui n, G. Yousef n & M. Lila n

author keywords: anthocyanins; cranberry; flavonoids; proanthocyanidins; processing
MeSH headings : Anthocyanins / analysis; Beverages; Biflavonoids / analysis; Catechin / analysis; Chromatography, High Pressure Liquid; Flavonoids / analysis; Food Handling / methods; Freeze Drying; Fruit / chemistry; Plant Extracts / analysis; Proanthocyanidins / analysis; Vaccinium macrocarpon / chemistry
TL;DR: As cranberry juices and other products are increasingly consumed for their recognized health benefits (including prophylaxis against urinary tract infection), it is relevant to consider how various degrees of commercial and home processing can alter innate levels of the biologically active flavonoids characteristic to the intact fruits. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Isolation and characterization of flavonols from blackcurrant by high-performance counter-current chromatography and electrospray ionization tandem mass spectrometry

JOURNAL OF SEPARATION SCIENCE, 35(13), 1682–1689.

By: F. Mbeunkui*, M. Grace*, G. Yousef* & M. Lila n

Contributors: F. Mbeunkui*, M. Grace*, G. Yousef* & M. Ann Lila n

author keywords: Blackcurrant (Ribes nigrum); Flavonols; High-performance counter-current chromatography; Liquid chromatography with tandem mass spectrometry
MeSH headings : Countercurrent Distribution / methods; Flavonols / chemistry; Flavonols / isolation & purification; Plant Extracts / chemistry; Plant Extracts / isolation & purification; Ribes / chemistry; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: The results of these experiments demonstrated that high-performance counter-current chromatography along with ESI-MS(n) is a sensitive, selective, and effective technology for isolation and characterization of minor constituents from a complex mixture. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Simultaneous extraction and quantitation of carotenoids, chlorophylls, and tocopherols in brassica vegetables

Journal of Agricultural and Food Chemistry, 60(29), 7238–7244.

By: I. Guzman, G. Yousef & A. Brown

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Complementary Approaches To Gauge the Bioavailability and Distribution of Ingested Berry Polyphenolics

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 60(23), 5763–5771.

By: M. Lila n, D. Ribnicky*, L. Rojo*, P. Rojas-Silva*, A. Oren*, R. Havenaar*, E. Janle*, I. Raskin* ...

Contributors: M. Lila n, D. Ribnicky*, L. Rojo*, P. Rojas-Silva*, A. Oren*, R. Havenaar*, E. Janle*, I. Raskin*, G. Yousef n, M. Grace n

author keywords: bioavailability; bioaccessibility; radiolabeling; artificial gastrointestinal tract
MeSH headings : Absorption; Animals; Anthocyanins / analysis; Anthocyanins / pharmacokinetics; Biological Availability; Blueberry Plants / chemistry; Carbon Isotopes / analysis; Carbon Isotopes / pharmacokinetics; Cell Line; Computer Simulation; Fruit / chemistry; Gastrointestinal Tract / drug effects; Gastrointestinal Tract / metabolism; Humans; Models, Biological; Phytochemicals / analysis; Phytochemicals / pharmacokinetics; Polyphenols / analysis; Polyphenols / pharmacokinetics; Rats; Vitis / chemistry
TL;DR: Two different strategies for investigating the likely fate, after ingestion, of natural, bioactive berry constituents (anthocyanins and other non-nutritive flavonoids) are compared. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Characterization of Anthocyanins and Proanthocyanidins in Wild and Domesticated Mexican Blackberries (Rubus spp.)

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 58(12), 7458–7464.

By: E. Cuevas-Rodriguez*, G. Yousef n, P. Garcia-Saucedo*, J. Lopez-Medina, O. Paredes-Lopez* & M. Lila n

author keywords: Anthocyanin; proanthocyanidin; ellagitannins; Rubus; HPLC-ESI-MS
MeSH headings : Anthocyanins / analysis; Fruit / chemistry; Fruit / genetics; Genotype; Mexico; Plant Extracts / analysis; Proanthocyanidins / analysis; Rosaceae / chemistry; Rosaceae / genetics
TL;DR: Recommendations for dietary intake of blackberries for human health benefits need to take into account the source, because of the wide inherent variation in bioactive polyphenolic content in different blackberry genotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Inhibition of Pro-inflammatory Responses and Antioxidant Capacity of Mexican Blackberry (Rubus spp.) Extracts

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 58(17), 9542–9548.

By: E. Cuevas-Rodriguez*, V. Dia*, G. Yousef n, P. Garcia-Saucedo*, J. Lopez-Medina, O. Paredes-Lopez*, E. Gonzalez De Mejia*, M. Ann Lila n

author keywords: Inflammation; wild blackberries; polyphenolic-rich fractions (PAE); antioxidant capacity; anthocyanins (ANC); proanthocyanidins (PAC); Rubus
MeSH headings : Animals; Antioxidants / pharmacology; Cell Line; Inflammation Mediators / pharmacology; Mice; Plant Extracts / pharmacology; Rosaceae / chemistry
TL;DR: Wild genotypes of Mexican blackberries, as rich sources of polyphenolics that have both antioxidant and anti-inflammatory properties, showed particular promise for inclusion in plant improvement programs designed to develop new varieties with nutraceutical potential. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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