Gisele C. Passador-Gurgel

Works (2)

Updated: July 5th, 2023 15:55

2007 journal article

Mixture modeling of transcript abundance classes in natural populations


By: W. Hsieh n, G. Passador-Gurgel n, E. Stone n & G. Gibson n

MeSH headings : Animals; California; Cell Line, Tumor; Drosophila melanogaster / genetics; Female; Gene Expression Profiling; Genetics, Population; Humans; Male; North Carolina; Transcription, Genetic
TL;DR: Population surveys of gene expression may complement genetical genomics as a general approach to quantifying sources of transcriptional variation by exploring the distributions of cis-acting and trans-acting factors and their relative contributions to expression of transcripts that exhibit two or more classes of abundance within populations. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Quantitative trait transcripts for nicotine resistance in Drosophila melanogaster

NATURE GENETICS, 39(2), 264–268.

By: G. Passador-Gurgel n, W. Hsieh*, P. Hunt n, N. Deighton n & G. Gibson n

MeSH headings : Animals; California; Drosophila melanogaster / drug effects; Drosophila melanogaster / genetics; Drug Resistance; Female; Genetic Linkage; Genetic Variation; Glutamate Decarboxylase / metabolism; Isoenzymes / metabolism; Longevity; Mice; Nicotine / pharmacology; North Carolina; Ornithine-Oxo-Acid Transaminase / metabolism; Quantitative Trait Loci; gamma-Aminobutyric Acid / metabolism
TL;DR: A complex role for ornithine and GABA levels in modification of survival time upon chronic nicotine exposure is confirmed and differences between populations from North Carolina and California suggest that the resistance mechanism may be an evolved response to environmental exposure. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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