Giuseppe Valacchi

Rizzo, R., Caccuri, F., Valacchi, G., & Zauli, G. (2023, February 1). Editorial: Cell cycle control as a new therapeutic approach for SARS-CoV-2 infection. FRONTIERS IN PHARMACOLOGY, Vol. 14. https://doi.org/10.3389/fphar.2023.1136277

Sarkar, P., Pecorelli, A., Woodby, B., Pambianchi, E., Ferrara, F., Duary, R. K., & Valacchi, G. (2023). Evaluation of Anti-Oxinflammatory and ACE-Inhibitory Properties of Protein Hydrolysates Obtained from Edible Non-Mulberry Silkworm Pupae (Antheraea assama and Philosomia ricinii). NUTRIENTS, 15(4). https://doi.org/10.3390/nu15041035

Pecorelli, A., Francesca, F., Cordone, V., Guiotto, A., Cervellati, C., Hayek, J., & Valacchi, G. (2022, February 20). Aberrant Mitochondrial Bioenergetics Fuels Inflammasome Machinery in Autism Spectrum Disorder. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 180, pp. 97–98. https://doi.org/10.1016/j.freeradbiomed.2021.12.227

Costa, S., Tedeschi, P., Ferraro, L., Beggiato, S., Grandini, A., Manfredini, S., … Valacchi, G. (2022). Biological activity of new bioactive steroids deriving from biotransformation of cortisone. MICROBIAL CELL FACTORIES, 21(1). https://doi.org/10.1186/s12934-022-01967-2

Astolfi, M., Rispoli, G., Benedusi, M., Zonta, G., Landini, N., Valacchi, G., & Malagu, C. (2022). Chemoresistive Sensors for Cellular Type Discrimination Based on Their Exhalations. NANOMATERIALS, 12(7). https://doi.org/10.3390/nano12071111

Ferrara, F., Benedusi, M., Cervellati, F., Sguizzato, M., Montesi, L., Bondi, A., … Esposito, E. (2022). Dimethyl Fumarate-Loaded Transethosomes: A Formulative Study and Preliminary Ex Vivo and In Vivo Evaluation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(15). https://doi.org/10.3390/ijms23158756

Trabalzini, L., Tundis, R., Valacchi, G., Evelson, P. A., & Finetti, F. (2022, May 30). Editorial: Angiogenesis and Nutraceuticals. FRONTIERS IN PHARMACOLOGY, Vol. 13. https://doi.org/10.3389/fphar.2022.943158

Ferrara, F., Benedusi, M., Sguizzato, M., Cortesi, R., Baldisserotto, A., Buzzi, R., … Esposito, E. (2022). Ethosomes and Transethosomes as Cutaneous Delivery Systems for Quercetin: A Preliminary Study on Melanoma Cells. PHARMACEUTICS, 14(5). https://doi.org/10.3390/pharmaceutics14051038

Pozzetti, L., Ferrara, F., Marotta, L., Gemma, S., Butini, S., Benedusi, M., … Campiani, G. (2022). Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals. ANTIOXIDANTS, 11(3). https://doi.org/10.3390/antiox11030437

Prieux, R., Ferrara, F., Cervellati, F., Guiotto, A., Benedusi, M., & Valacchi, G. (2022, April 15). Inflammasome involvement in CS-induced damage in HaCaT keratinocytes. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, Vol. 4. https://doi.org/10.1007/s11626-022-00658-x

Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Cervellati, C., Hayek, J., … Pecorelli, A. (2022, November 1). Involvement Of Ferroptosis In Rett Syndrome. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192. https://doi.org/10.1016/j.freeradbiomed.2022.10.054

Pecorelli, A., Ferrara, F., Guiotto, A., Vallese, A., Cordone, V., Belmonte, G., … Valacchi, G. (2022, November 1). Loss of Scavenger Receptor B1 (SR-B1) in Brain of a Rett Syndrome Mouse Model. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192. https://doi.org/10.1016/j.freeradbiomed.2022.10.159

Valacchi, G., Pambianchi, E., Coco, S., Pulliero, A., & Izzotti, A. (2022). MicroRNA Alterations Induced in Human Skin by Diesel Fumes, Ozone, and UV Radiation. JOURNAL OF PERSONALIZED MEDICINE, 12(2). https://doi.org/10.3390/jpm12020176

Pasqui, A., Cicaloni, V., Tinti, L., Mori, A., Bruttini, M., Pecorelli, A., … Valacchi, G. (2022, November 1). Mutations Specific Redox Regulation Pathway In Rett Syndrome By The Use Of Transcriptomics And Proteomics Approaches. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192. https://doi.org/10.1016/j.freeradbiomed.2022.10.062

Pecorelli, A., & Valacchi, G. (2022). [Review of Oxidative-Stress-Sensitive microRNAs in UV-Promoted Development of Melanoma]. CANCERS, 14(13). https://doi.org/10.3390/cancers14133224

Cordone, V., Ferrara, F., Pecorelli, A., Guiotto, A., Vitale, A., Amicarelli, F., … Valacchi, G. (2022). The constitutive activation of TLR4-IRAK1-NF kappa B axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients. FREE RADICAL BIOLOGY AND MEDICINE, 181, 1–13. https://doi.org/10.1016/j.freeradbiomed.2022.01.017

Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., … Valacchi, G. (2022). Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation. REDOX BIOLOGY, 56. https://doi.org/10.1016/j.redox.2022.102440

Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., … Valacchi, G. (2022, November 1). Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192. https://doi.org/10.1016/j.freeradbiomed.2022.10.033

Farris, P. K., & Valacchi, G. (2022). [Review of Ultraviolet Light Protection: Is It Really Enough?]. ANTIOXIDANTS, 11(8). https://doi.org/10.3390/antiox11081484

Sguizzato, M., Ferrara, F., Mariani, P., Pepe, A., Cortesi, R., Huang, N., … Esposito, E. (2021). "Plurethosome" as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation. PHARMACEUTICS, 13(8). https://doi.org/10.3390/pharmaceutics13081124

Pambianchi, E., Hagenberg, Z., Pecorelli, A., Grace, M., Therrien, J.-P., Lila, M. A., & Valacchi, G. (2021). Alaskan Bog Blueberry (Vaccinium uliginosum) Extract as an Innovative Topical Approach to Prevent UV-Induced Skin Damage. COSMETICS, 8(4). https://doi.org/10.3390/cosmetics8040112

Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, March). Alteration of cellular defensive response and a possible involvement of ferroptosis cell death in Rett syndrome disorder. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165. https://doi.org/10.1016/j.freeradbiomed.2020.12.403

Garces, M., Magnani, N. D., Pecorelli, A., Calabro, V., Marchini, T., Caceres, L., … Evelson, P. (2021). Alterations in oxygen metabolism are associated to lung toxicity triggered by silver nanoparticles exposure. FREE RADICAL BIOLOGY AND MEDICINE, 166, 324–336. https://doi.org/10.1016/j.freeradbiomed.2021.02.008

Pecorelli, A., Cordone, V., Schiavone, M. L., Caffarelli, C., Cervellati, C., Cerbone, G., … Valacchi, G. (2021). [Review of Altered Bone Status in Rett Syndrome]. LIFE-BASEL, 11(6). https://doi.org/10.3390/life11060521

Cervellati, C., Valacchi, G., & Zuliani, G. (2021, December). BACE1 role in Alzheimer's disease and other dementias: from the theory to the practice. NEURAL REGENERATION RESEARCH, Vol. 16, pp. 2407–2408. https://doi.org/10.4103/1673-5374.313041

Petracca, B., Rothen-Rutishauser, B., Valacchi, G., & Eeman, M. (2021). [Review of Bench approaches to study the detrimental cutaneous impact of tropospheric ozone]. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 31(1), 137–148. https://doi.org/10.1038/s41370-020-00275-4

Benedusi, M., Frigato, E., Bertolucci, C., & Valacchi, G. (2021). Circadian Deregulation as Possible New Player in Pollution-Induced Tissue Damage. ATMOSPHERE, 12(1). https://doi.org/10.3390/atmos12010116

Zimetti, F., Adorni, M. P., Marsillach, J., Marchi, C., Trentini, A., Valacchi, G., & Cervellati, C. (2021). [Review of Connection between the Altered HDL Antioxidant and Anti-Inflammatory Properties and the Risk to Develop Alzheimer's Disease: A Narrative Review]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021. https://doi.org/10.1155/2021/6695796

Dijkhoff, I. M., Petracca, B., Prieux, R., Valacchi, G., Rothen-Rutishauser, B., & Eeman, M. (2021). Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 5(171). https://doi.org/10.3791/61802

Pambianchi, E., Ferrara, F., Pecorelli, A., Benedusi, M., Choudhary, H., Therrien, J.-P., & Valacchi, G. (2021). Deferoxamine Treatment Improves Antioxidant Cosmeceutical Formulation Protection against Cutaneous Diesel Engine Exhaust Exposure. ANTIOXIDANTS, 10(12). https://doi.org/10.3390/antiox10121928

Cordone, V., Pecorelli, A., Falone, S., Hayek, J., Amicarelli, F., & Valacchi, G. (2021, December). Deregulated inflammasome response in Rett syndrome. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177. https://doi.org/10.1016/j.freeradbiomed.2021.08.158

Sguizzato, M., Ferrara, F., Hallan, S. S., Baldisserotto, A., Drechsler, M., Malatesta, M., … Esposito, E. (2021). Ethosomes and Transethosomes for Mangiferin Transdermal Delivery. ANTIOXIDANTS, 10(5). https://doi.org/10.3390/antiox10050768

Costanzo, M., Esposito, E., Sguizzato, M., Lacavalla, M. A., Drechsler, M., Valacchi, G., … Malatesta, M. (2021). Formulative Study and Intracellular Fate Evaluation of Ethosomes and Transethosomes for Vitamin D3 Delivery. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(10). https://doi.org/10.3390/ijms22105341

Crivellari, I., Pecorelli, A., Cordone, V., Marchi, S., Pinton, P., Hayek, J., … Valacchi, G. (2021). Impaired mitochondrial quality control in Rett Syndrome. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 700. https://doi.org/10.1016/j.abb.2021.108790

Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, December). Improper enzymatic defensive responses in Rett syndrome disorder. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177. https://doi.org/10.1016/j.freeradbiomed.2021.08.165

Ferrara, F., Prieux, R., Woodby, B., & Valacchi, G. (2021). Inflammasome Activation in Pollution-Induced Skin Conditions. PLASTIC AND RECONSTRUCTIVE SURGERY, 147(1S-2), 15S–24S. https://doi.org/10.1097/PRS.0000000000007617

Pecorelli, A., Guiotto, A., Cordone, V., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, December). Mitochondrial dynamics and quality control pathways impairment in Rett Syndrome and Autism Spectrum Disorder. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177, pp. S17–S18. https://doi.org/10.1016/j.freeradbiomed.2021.08.070

Pecorelli, A., Cordone, V., Guiotto, A., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, March). Mitochondrial dysfunction fuels inflammasome machinery in Autism Spectrum Disorder. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165. https://doi.org/10.1016/j.freeradbiomed.2020.12.410

Prieux, R., Benedusi, M., Ferrara, F., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). NALP1 involvement in cigarette smoke induces cutaneous inflammation. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165. https://doi.org/10.1016/j.freeradbiomed.2020.12.370

Hoskin, R., Pambianchi, E., Pecorelli, A., Grace, M., Therrien, J.-P., Valacchi, G., & Lila, M. A. (2021). Novel Spray Dried Algae-Rosemary Particles Attenuate Pollution-Induced Skin Damage. MOLECULES, 26(13). https://doi.org/10.3390/molecules26133781

Garces, M., Marchini, T., Caceres, L., Calabro, V., Mebert, A. M., Victoria Tuttolomondo, M., … Evelson, P. A. (2021). Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice. TOXICOLOGY, 464. https://doi.org/10.1016/j.tox.2021.153020

Sarkar, P., Valacchi, G., & Duary, R. K. (2021, October 28). Proteome composition and profiling of bioactive peptides of edible Antheraea assamensis pupae by sequential enzymatic digestion and kinetic modeling of in vitro gastrointestinal digestion. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, Vol. 10. https://doi.org/10.1007/s00217-021-03882-z

Woodby, B., Arnold, M. M., & Valacchi, G. (2021). [Review of SARS-CoV-2 infection, COVID-19 pathogenesis, and exposure to air pollution: What is the connection?]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1486(1), 15–38. https://doi.org/10.1111/nyas.14512

Grillo, A., Fezza, F., Chemi, G., Colangeli, R., Brogi, S., Fazio, D., … Di Giovanni, G. (2021). Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents. ACS CHEMICAL NEUROSCIENCE, 12(9), 1716–1736. https://doi.org/10.1021/acschemneuro.1c00192

Canella, R., Benedusi, M., Martini, M., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, May 7). The role of pulmonary ORCC and CLC-2 channels in the response to oxidative stress. MOLECULAR & CELLULAR TOXICOLOGY, Vol. 5. https://doi.org/10.1007/s13273-021-00137-6

Ferrara, F., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165. https://doi.org/10.1016/j.freeradbiomed.2020.12.303

Cicaloni, V., Pecorelli, A., Cordone, V., Tinti, L., Rossi, M., Hayek, J., … Valacchi, G. (2020). A proteomics approach to further highlight the altered inflammatory condition in Rett syndrome. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 696. https://doi.org/10.1016/j.abb.2020.108660

Pecorelli, A., Ferrara, F., Messano, N., Cordone, V., Schiavone, M. L., Cervellati, F., … Valacchi, G. (2020). Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder. FASEB JOURNAL, 34(5), 6521–6538. https://doi.org/10.1096/fj.201902677R

Pecorelli, A., Cordone, V., Messano, N., Zhang, C., Falone, S., Amicarelli, F., … Valacchi, G. (2020). Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation. REDOX BIOLOGY, 28. https://doi.org/10.1016/j.redox.2019.101334

Frigato, E., Benedusi, M., Guiotto, A., Bertolucci, C., & Valacchi, G. (2020). Circadian Clock and OxInflammation: Functional Crosstalk in Cutaneous Homeostasis. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2020. https://doi.org/10.1155/2020/2309437

Sbardella, D., Tundo, G. R., Cunsolo, V., Grasso, G., Cascella, R., Caputo, V., … Marini, S. (2020). Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1866(7). https://doi.org/10.1016/j.bbadis.2020.165793

Sguizzato, M., Mariani, P., Spinozzi, F., Benedusi, M., Cervellati, F., Cortesi, R., … Esposito, E. (2020). Ethosomes for Coenzyme Q10 Cutaneous Administration: From Design to 3D Skin Tissue Evaluation. ANTIOXIDANTS, 9(6). https://doi.org/10.3390/antiox9060485

Sguizzato, M., Valacchi, G., Pecorelli, A., Boldrini, P., Simeliere, F., Huang, N., … Esposito, E. (2020). Gallic acid loaded poloxamer gel as new adjuvant strategy for melanoma: A preliminary study. COLLOIDS AND SURFACES B-BIOINTERFACES, 185. https://doi.org/10.1016/j.colsurfb.2019.110613

Dijkhoff, I. M., Drasler, B., Karakocak, B. B., Petri-Fink, A., Valacchi, G., Eeman, M., & Rothen-Rutishauser, B. (2020). [Review of Impact of airborne particulate matter on skin: a systematic review from epidemiology to in vitro studies]. PARTICLE AND FIBRE TOXICOLOGY, 17(1). https://doi.org/10.1186/s12989-020-00366-y

Zuliani, G., Trentini, A., Rosta, V., Guerrini, R., Pacifico, S., Bonazzi, S., … Cervellati, C. (2020). Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease. SCIENTIFIC REPORTS, 10(1). https://doi.org/10.1038/s41598-020-72168-3

Cervellati, C., Trentini, A., Pecorelli, A., & Valacchi, G. (2020). Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery. ANTIOXIDANTS & REDOX SIGNALING, 33(3), 191–210. https://doi.org/10.1089/ars.2020.8076

Ercoli, J., Finetti, F., Woodby, B., Belmonte, G., Miracco, C., Valacchi, G., & Trabalzini, L. (2020). KRIT1 as a possible new player in melanoma aggressiveness. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 691. https://doi.org/10.1016/j.abb.2020.108483

Schiavone, M. L., Pecorelli, A., Woodby, B., Ferrara, F., Pambianchi, E., Santucci, A., & Valacchi, G. (2020). Mechanisms involved in the unbalanced redox homeostasis in osteoblastic cellular model of Alkaptonuria. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 690. https://doi.org/10.1016/j.abb.2020.108416

Prieux, R., Eeman, M., Rothen-Rutishauser, B., & Valacchi, G. (2020). [Review of Mimicking cigarette smoke exposure to assess cutaneous toxicity]. TOXICOLOGY IN VITRO, 62. https://doi.org/10.1016/j.tiv.2019.104664

Nieman, D. C., Valacchi, G., Wentz, L. M., Ferrara, F., Pecorelli, A., Woodby, B., … Simonson, A. (2020). Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(2), 112–119. https://doi.org/10.1123/ijsnem.2019-0171

Caceres, L., Paz, M. L., Garces, M., Calabro, V., Magnani, N. D., Martinefski, M., … Evelson, P. (2020). NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxinflammatory response of macrophages exposed to airborne particulate matter. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 205. https://doi.org/10.1016/j.ecoenv.2020.111186

Sguizzato, M., Mariani, P., Ferrara, F., Drechsler, M., Hallan, S. S., Huang, N., … Esposito, E. (2020). Nanoparticulate Gels for Cutaneous Administration of Caffeic Acid. NANOMATERIALS, 10(5). https://doi.org/10.3390/nano10050961

Valacchi, G., Magnani, N., Woodby, B., Maria Ferreira, S., & Evelson, P. (2020). Particulate Matter Induces Tissue OxInflammation: From Mechanism to Damage. ANTIOXIDANTS & REDOX SIGNALING, 33(4), 308–326. https://doi.org/10.1089/ars.2019.8015

Nieman, D. C., Ferrara, F., Pecorelli, A., Woodby, B., Hoyle, A. T., Simonson, A., & Valacchi, G. (2020). Postexercise Inflammasome Activation and IL-1 beta Production Mitigated by Flavonoid Supplementation in Cyclists. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(6), 396–404. https://doi.org/10.1123/ijsnem.2020-0084

Cicaloni, V., Pecorelli, A., Tinti, L., Rossi, M., Benedusi, M., Cervellati, C., … Valacchi, G. (2020). Proteomic pro fi ling reveals mitochondrial alterations in Rett syndrome. FREE RADICAL BIOLOGY AND MEDICINE, 155, 37–48. https://doi.org/10.1016/j.freeradbiomed.2020.05.014

Ferrara, F., Pambianchi, E., Pecorelli, A., Woodby, B., Messano, N., Therrien, J.-P., … Valacchi, G. (2020). Redox regulation of cutaneous inflammasome by ozone exposure. FREE RADICAL BIOLOGY AND MEDICINE, 152, 561–570. https://doi.org/10.1016/j.freeradbiomed.2019.11.031

Cervellati, C., Trentini, A., Rosta, V., Passaro, A., Bosi, C., Sanz, J. M., … Zuliani, G. (2020). Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer's disease. GEROSCIENCE, 42(1), 159–167. https://doi.org/10.1007/s11357-019-00127-6

Woodby, B., Penta, K., Pecorelli, A., Lila, M. A., & Valacchi, G. (2020). Skin Health from the Inside Out. ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 235–254. https://doi.org/10.1146/annurev-food-032519-051722

Woodby, B., Sticozzi, C., Pambianchi, E., Villetti, G., Civelli, M., Valacchi, G., & Facchinetti, F. (2020). The PDE4 inhibitor CHF6001 affects keratinocyte proliferation via cellular redox pathways. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 685. https://doi.org/10.1016/j.abb.2020.108355

Pecorelli, A., Cervellati, C., Cordone, V., Amicarelli, F., Hayek, J., & Valacchi, G. (2019). 13-HODE, 9-HODE and ALOX15 as potential players in Rett syndrome OxInflammation. FREE RADICAL BIOLOGY AND MEDICINE, 134, 598–603. https://doi.org/10.1016/j.freeradbiomed.2019.02.007

Cordone, V., Pecorelli, A., Benedusi, M., Santini, S., Jr., Falone, S., Hayek, J., … Valacchi, G. (2019). Antiglycative Activity and RAGE Expression in Rett Syndrome. CELLS, 8(2). https://doi.org/10.3390/cells8020161

Pambianchi, E., Francesca, F., Pecorelli, A., Woodby, B., Lila, M., & Valacchi, G. (2019, December). Blueberries Topical Application Prevents Ozone Induced Cutaneous Inflammasome Activation. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S148–S148. https://doi.org/10.1016/j.freeradbiomed.2019.10.393

Caffarelli, C., Francolini, V., Hayek, J., Valacchi, G., Giannotti, S., Nuti, R., & Gonnelli, S. (2019). Bone status in relation to ambulatory performance in girls with Rett syndrome: a 10-year longitudinal study. PEDIATRIC RESEARCH, 85(5), 639–643. https://doi.org/10.1038/s41390-018-0111-z

Prieux, R., Valacchi, G., Benedusi, M., & Cervellati, F. (2019, December). Comparing Skin Aging in Vitro Induced by External and Internal Cigarette Smoke Exposure. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S137–S137. https://doi.org/10.1016/j.freeradbiomed.2019.10.365

Bortolotti, D., Trapella, C., Bragonzi, A., Marchetti, P., Zanirato, V., Alogna, A., … Rizzo, R. (2019). Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains. JOURNAL OF CHEMISTRY, 2019. https://doi.org/10.1155/2019/8143739

Grillo, A., Chemi, G., Brogi, S., Brindisi, M., Relitti, N., Fezza, F., … Gemma, S. (2019). Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 183. https://doi.org/10.1016/j.ejmech.2019.111674

Cervellati, C., Valacchi, G., Tisato, V., Zuliani, G., & Marsillach, J. (2019). [Review of Evaluating the link between Paraoxonase-1 levels and Alzheimer's disease development]. MINERVA MEDICA, 110(3), 238–250. https://doi.org/10.23736/S0026-4806.18.05875-5

Schiavone, M. L., Pecorelli, A., Woodby, B., Ferrara, F., Santucci, A., & Valacchi, G. (2019, December). HGA Induces Oxidative Damage in an Ostcoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms HGA Induces Oxidative Damage in an Osteoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S37–S38. https://doi.org/10.1016/j.freeradbiomed.2019.10.095

Pecorelli, A., Woodby, B., Prieux, R., & Valacchi, G. (2019). [Review of Involvement of 4-hydroxy-2-nonenal in pollution-induced skin damage]. BIOFACTORS, 45(4), 536–547. https://doi.org/10.1002/biof.1513

Muresan, X. M., Narzt, M.-S., Woodby, B., Ferrara, F., Gruber, F., & Valacchi, G. (2019). Involvement of cutaneous SR-B1 in skin lipid homeostasis. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 666, 1–7. https://doi.org/10.1016/j.abb.2019.03.005

Canella, R., Martini, M., Cavicchio, C., Cervellati, F., Benedusi, M., & Valacchi, G. (2019). Involvement of the TREK-1 channel in human alveolar cell membrane potential and its regulation by inhibitors of the chloride current. JOURNAL OF CELLULAR PHYSIOLOGY, 234(10), 17704–17713. https://doi.org/10.1002/jcp.28396

Esposito, E., Sguizzato, M., Drechsler, M., Mariani, P., Carducci, F., Nastruzzi, C., … Cortesi, R. (2019). Lipid nanostructures for antioxidant delivery: a comparative preformulation study. BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 10, 1789–1801. https://doi.org/10.3762/bjnano.10.174

Ietta, F., Valacchi, G., Benincasa, L., Pecorelli, A., Cresti, L., & Maioli, E. (2019). Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells. BIOFACTORS, 45(6), 920–929. https://doi.org/10.1002/biof.1551

Pecorelli, A., Valacchi, G., Cordone, V., & Hayek, J. (2019, December). OxInflammation as a Aossible new Player in Rett Syndrome Pathophysiology. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S149–S149. https://doi.org/10.1016/j.freeradbiomed.2019.10.396

Lim, Y., Lee, H., Woodby, B., & Valacchi, G. (2019). [Review of Ozonated Oils and Cutaneous Wound Healing]. CURRENT PHARMACEUTICAL DESIGN, 25(20), 2264–2278. https://doi.org/10.2174/1381612825666190702100504

Ferrara, F., Pecorelli, A., Woodby, B., Pambianchi, E., Messano, N., Therrien, J. P., & Valacchi, G. (2019, December). Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23. https://doi.org/10.1016/j.freeradbiomed.2019.10.055

Ferrara, F., Pecorelli, A., Woodby, B., Pambianchi, E., Messano, N., Therrien, J. P., & Valacchi, G. (2019). Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23. https://doi.org/10.1016./j.freeradbiomed.2019.10.055

Woodby, B., Pambianchi, E., Francesca, F., Messano, N., Pecorelli, A., Therrien, J. P., & Valacchii, G. (2019, December). Redox-Regulation of Antimicrobial Peptides. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S54–S55. https://doi.org/10.1016/j.freeradbiomed.2019.10.142

Fuks, K. B., Woodby, B., & Valacchi, G. (2019). Skin damage by tropospheric ozone. HAUTARZT, 70(3), 163–168. https://doi.org/10.1007/s00105-019-4361-4

Allavena, G., Del Bello, B., Tini, P., Volpi, N., Valacchi, G., Miracco, C., … Maellaro, E. (2019). Trehalose inhibits cell proliferation and amplifies long-term temozolomide- and radiation-induced cytotoxicity in melanoma cells: A role for autophagy and premature senescence. JOURNAL OF CELLULAR PHYSIOLOGY, 234(7), 11708–11721. https://doi.org/10.1002/jcp.27838

Valacchi, G., Pecorelli, A., Pambianchi, E., Ferrara, F., & Lila, M. (2018, September). AtmO(3)spheric skin damage: The oxInflammation phenomena. JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B15–B15. https://doi.org/10.1016/j.jid.2018.06.089

Benedusi, M., Frigato, E., Beltramello, M., Bertolucci, C., & Valacchi, G. (2018). Circadian clock as possible protective mechanism to pollution induced keratinocytes damage. Mechanisms of Ageing and Development, 172, 13–20. https://doi.org/10.1016/J.MAD.2017.08.017

Brindisi, M., Borrelli, G., Brogi, S., Grillo, A., Maramai, S., Paolino, M., … Gemma, S. (2018). Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain. ChemMedChem, 13(19), 2090–2103. https://doi.org/10.1002/CMDC.201800397

Pecorelli, A., Cordone, V., Falone, S., Romani, A., Benedusi, M., Hayek, J., … Valacchi, G. (2018, November 20). Inflammasome involvement in Rett syndrome subclinical inflammation. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 128, pp. S108–S109. https://doi.org/10.1016/j.freeradbiomed.2018.10.262

Romani, A., Cervellati, C., Muresan, X. M., Belmonte, G., Pecorelli, A., Cervellati, F., … Valacchi, G. (2018). Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure. MECHANISMS OF AGEING AND DEVELOPMENT, 172, 86–95. https://doi.org/10.1016/j.mad.2017.11.007

Foscolou, A., Magriplis, E., Tyrovolas, S., Soulis, G., Bountziouka, V., Mariolis, A., … Panagiotakos, D. (2018). Lifestyle determinants of healthy ageing in a Mediterranean population: The multinational MEDIS study. Experimental Gerontology, 110, 35–41. https://doi.org/10.1016/J.EXGER.2018.05.008

Cervellati, C., Trentini, A., Bosi, C., Valacchi, G., Morieri, M. L., Zurlo, A., … Zuliani, G. (2018). Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia. GeroScience, 40(1), 61–69. https://doi.org/10.1007/S11357-018-0010-6

Masana, M. F., Haro, J. M., Mariolis, A., Piscopo, S., Valacchi, G., Bountziouka, V., … Panagiotakos, D. B. (2018). Mediterranean diet and depression among older individuals: The multinational MEDIS study. Experimental Gerontology, 110, 67–72. https://doi.org/10.1016/J.EXGER.2018.05.012

Muresan, X. M., Sticozzi, C., Belmonte, G., Savelli, V., Evelson, P., & Valacchi, G. (2018). Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs “in vitro” wound closure. Mechanisms of Ageing and Development, 172, 78–85. https://doi.org/10.1016/J.MAD.2017.11.006

Maioli, E., Daveri, E., Maellaro, E., Ietta, F., Cresti, L., & Valacchi, G. (2018). Non-conventional rottlerin anticancer properties. Archives of Biochemistry and Biophysics, 645, 50–53. https://doi.org/10.1016/J.ABB.2018.03.009

Valacchi, G., Pecorelli, A., & Cervellati, C. (2018). OXINFLAMMATION IN RETT SYNDROME. Pathophysiology, 25(3), 189. https://doi.org/10.1016/J.PATHOPHYS.2018.07.069

Valacchi, G., Virgili, F., Cervellati, C., & Pecorelli, A. (2018). [Review of OxInflammation: From Subclinical Condition to Pathological Biomarker]. FRONTIERS IN PHYSIOLOGY, 9. https://doi.org/10.3389/fphys.2018.00858

Canella, R., Benedusi, M., Martini, M., Cervellati, F., Cavicchio, C., & Valacchi, G. (2018). Role of Nrf2 in preventing oxidative stress induced chloride current alteration in human lung cells. Journal of Cellular Physiology, 233(8), 6018–6027. https://doi.org/10.1002/JCP.26416

Muresan, X. M., Sticozzi, C., Belmonte, G., Cervellati, F., Ferrara, F., Lila, M. A., & Valacchi, G. (2018). SR-B1 involvement in keratinocytes in vitro wound closure. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 658, 1–6. https://doi.org/10.1016/j.abb.2018.09.014

Valacchi, G., Muresan, X., Belmonte, G., Pecorelli, A., & Gruber, F. (2018, September). Scavenger receptor B1 as a possible new player in cutaneous tissue proliferation and differentiation. JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B25–B25. https://doi.org/10.1016/j.jid.2018.06.155

Sticozzi, C., Pecorelli, A., Romani, A., Belmonte, G., Cervellati, F., Maioli, E., … Valacchi, G. (2018). Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells. FREE RADICAL BIOLOGY AND MEDICINE, 126, 287–295. https://doi.org/10.1016/j.freeradbiomed.2018.07.007

Valacchi, G., Pecorelli, A., Cervellati, C., & Hayek, J. (2017). [Review of 4-hydroxynonenal protein adducts: Key mediator in Rett syndrome oxinflammation]. FREE RADICAL BIOLOGY AND MEDICINE, 111, 270–280. https://doi.org/10.1016/j.freeradbiomed.2016.12.045

Brogi, S., Ramunno, A., Savi, L., Chemi, G., Alfano, G., Pecorelli, A., … Brindisi, M. (2017). First dual AK/GSK-3 beta inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 138, 438–457. https://doi.org/10.1016/j.ejmech.2017.06.017

Tyrovolas, S., Polychronopoulos, E., Morena, M., Mariolis, A., Piscopo, S., Valacchi, G., … Panagiotakos, D. (2017). Is car use related with successful aging of older adults? Results from the multinational Mediterranean islands study. Annals of Epidemiology, 27(3), 225–229. https://doi.org/10.1016/J.ANNEPIDEM.2016.12.006

Georgousopoulou, E. N., Mellor, D. D., Naumovski, N., Polychronopoulos, E., Tyrovolas, S., Piscopo, S., … Matalas, A. L. (2017). Mediterranean lifestyle and cardiovascular disease prevention. Cardiovascular Diagnosis and Therapy, 7, S39–47.

Canella, R., Martini, M., Borriello, R., Cavicchio, C., Muresan, X. M., Benedusi, M., … Valacchi, G. (2017). Modulation of Chloride Currents in Human Lung Epithelial Cells Exposed to Exogenous Oxidative Stress. JOURNAL OF CELLULAR PHYSIOLOGY, 232(7), 1817–1825. https://doi.org/10.1002/jcp.25705

Cortesi, R., Cappellozza, E., Drechsler, M., Contado, C., Baldisserotto, A., Mariani, P., … Valacchi, G. (2017). Monoolein aqueous dispersions as a delivery system for quercetin. Biomedical Microdevices, 19(2). https://doi.org/10.1007/S10544-017-0185-0

Cortesi, R., Valacchi, G., Muresan, X. M., Drechsler, M., Contado, C., Esposito, E., … Sacchetti, G. (2017). Nanostructured lipid carriers (NLC) for the delivery of natural molecules with antimicrobial activity: production, characterisation and in vitro studies. Journal of Microencapsulation, 34(1), 63–72. https://doi.org/10.1080/02652048.2017.1284276

Rosseto, H. C., Toledo, L. de A. S. de, Francisco, L. M. B. de, Esposito, E., Lim, Y., Valacchi, G., … Bruschi, M. L. (2017). Nanostructured lipid systems modified with waste material of propolis for wound healing: Design, in vitro and in vivo evaluation. Colloids and Surfaces B: Biointerfaces, 158, 441–452. https://doi.org/10.1016/J.COLSURFB.2017.07.029

Fallacara, A., Vertuani, S., Panozzo, G., Pecorelli, A., Valacchi, G., & Manfredini, S. (2017). Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study. MOLECULES, 22(12). https://doi.org/10.3390/molecules22122104

Cervellati, C., Bonaccorsi, G., Trentini, A., Valacchi, G., Sanz, J. M., Squerzanti, M., … Ricci, G. (2017). Paraoxonase, arylesterase and lactonase activities of paraoxonase-1 (PON1) in obese and severely obese women. Scandinavian Journal of Clinical and Laboratory Investigation, 78(1-2), 18–24. https://doi.org/10.1080/00365513.2017.1405274

Cavicchio, C., Benedusi, M., Pambianchi, E., Pecorelli, A., Cervellati, F., Savelli, V., … Valacchi, G. (2017). Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017. https://doi.org/10.1155/2017/4256519

Valacchi, G., Pecorelli, A., Belmonte, G., Pambianchi, E., Cervellati, F., Lynch, S., … Oresajo, C. (2017). Protective Effects of Topical Vitamin C Compound Mixtures against Ozone-Induced Damage in Human Skin. Journal of Investigative Dermatology, 137(6), 1373–1375. https://doi.org/10.1016/J.JID.2017.01.034

Chedea, V. S., Vicaş, S. I., Sticozzi, C., Pessina, F., Frosini, M., Maioli, E., & Valacchi, G. (2017). Resveratrol: from diet to topical usage. Food & Function, 8(11), 3879–3892. https://doi.org/10.1039/C7FO01086A

Sbardella, D., Tundo, G. R., Campagnolo, L., Valacchi, G., Orlandi, A., Curatolo, P., … Marini, S. (2017). Retention of mitochondria in mature human red blood cells as the result of autophagy impairment in Rett syndrome. Scientific Reports, 7. https://doi.org/10.1038/s41598-017-12069-0

Crivellari, I., Cervellati, C., Dalla Sega, F. V., Valacchi, G., Trentini, A., Passaro, A., … Rizzo, P. (2017, July). Serum from patients affected by Alzheimer disease shows a paraoxonase-dependent pro-apoptotic effect on endothelial cells. FREE RADICAL BIOLOGY AND MEDICINE, Vol. 108, pp. S93–S93. https://doi.org/10.1016/j.freeradbiomed.2017.04.304

Cortelazzo, A., De Felice, C., Guerranti, R., Signorini, C., Leoncini, S., Pecorelli, A., … Hayek, J. (2016). Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome. Neuroscience Research, 105, 28–34. https://doi.org/10.1016/J.NEURES.2015.10.002

Georgousopoulou, E. N., Naumovski, N., Mellor, D. D., Tyrovolas, S., Piscopo, S., Valacchi, G., … Panagiotakos, D. B. (2016). Association between siesta (daytime sleep), dietary patterns and the presence of metabolic syndrome in elderly living in Mediterranean area (MEDIS study): The moderating effect of gender. The Journal of Nutrition, Health & Aging, 21(10), 1118–1124. https://doi.org/10.1007/S12603-016-0865-0

Pecorelli, A., Cervellati, F., Belmonte, G., Montagner, G., Waldon, P. A., Hayek, J., … Valacchi, G. (2016). Cytokines profile and peripheral blood mononuclear cells morphology in Rett and autistic patients. Cytokine, 77, 180–188. https://doi.org/10.1016/J.CYTO.2015.10.002

Castellazzi, M., Trentini, A., Romani, A., Valacchi, G., Bellini, T., Bonaccorsi, G., … Cervellati, C. (2016). Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases. The International Journal of Biochemistry & Cell Biology, 81, 356–363. https://doi.org/10.1016/J.BIOCEL.2016.06.008

Aiello, F., Badolato, M., Pessina, F., Sticozzi, C., Maestrini, V., Aldinucci, C., … Brizzi, A. (2016). Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. ACS Chemical Neuroscience, 7(6), 737–748. https://doi.org/10.1021/ACSCHEMNEURO.5B00333

Daveri, E., Maellaro, E., Valacchi, G., Ietta, F., Muscettola, M., & Maioli, E. (2016). Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing. Cancer Letters, 380(1), 106–113. https://doi.org/10.1016/J.CANLET.2016.06.018

Pecorelli, A., Cervellati, C., Hayek, J., & Valacchi, G. (2016). OxInflammation in Rett syndrome. The International Journal of Biochemistry & Cell Biology, 81, 246–253. https://doi.org/10.1016/J.BIOCEL.2016.07.015

Valacchi, G., Sticozzi, C., Zanardi, I., Belmonte, G., Cervellati, F., Bocci, V., & Travagli, V. (2016). Ozone mediators effect on “in vitro” scratch wound closure. Free Radical Research, 50(9), 1022–1031. https://doi.org/10.1080/10715762.2016.1219731

Valacchi, G., Muresan, X. M., Sticozzi, C., Belmonte, G., Pecorelli, A., Cervellati, F., … Oresajo, C. (2016). Ozone-induced damage in 3D-Skin Model is prevented by topical vitamin C and vitamin E compound mixtures application. Journal of Dermatological Science, 82(3), 209–212. https://doi.org/10.1016/J.JDERMSCI.2016.02.007

Pecorelli, A., Cervellati, C., Cortelazzo, A., Cervellati, F., Sticozzi, C., Mirasole, C., … Valacchi, G. (2016). Proteomic analysis of 4-hydroxynonenal and nitrotyrosine modified proteins in RTT fibroblasts. The International Journal of Biochemistry & Cell Biology, 81, 236–245. https://doi.org/10.1016/J.BIOCEL.2016.08.001

Valacchi, G., Cervellati, C., Evelson, P., & Rahman, I. (2016). Redox regulation of inflammatory processes. The International Journal of Biochemistry & Cell Biology, 81, 234–235. https://doi.org/10.1016/J.BIOCEL.2016.11.002

Tyrovolas, S., Haro, J.-M., Mariolis, A., Piscopo, S., Valacchi, G., Bountziouka, V., … Panagiotakos, D. (2016). Skeletal muscle mass and body fat in relation to successful ageing of older adults: The multi-national MEDIS study. Archives of Gerontology and Geriatrics, 66, 95–101. https://doi.org/10.1016/J.ARCHGER.2016.04.017

Di Capua, A., Sticozzi, C., Brogi, S., Brindisi, M., Cappelli, A., Sautebin, L., … Anzini, M. (2016). Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity. European Journal of Medicinal Chemistry, 109, 99–106. https://doi.org/10.1016/J.EJMECH.2015.12.044

Wood, P. L., Locke, V. A., Herling, P., Passaro, A., Vigna, G. B., Volpato, S., … Zuliani, G. (2016). Targeted lipidomics distinguishes patient subgroups in mild cognitive impairment (MCI) and late onset Alzheimer's disease (LOAD). BBA Clinical, 5, 25–28. https://doi.org/10.1016/J.BBACLI.2015.11.004

Cheleschi, S., Pascarelli, N. A., Valacchi, G., Di Capua, A., Biava, M., Belmonte, G., … Fioravanti, A. (2015). Chondroprotective effect of three different classes of anti-inflammatory agents on human osteoarthritic chondrocytes exposed to IL-1β. International Immunopharmacology, 28(1), 794–801. https://doi.org/10.1016/J.INTIMP.2015.07.003

Valacchi, G., Grisci, G., Sticozzi, C., Lim, Y., Paolino, M., Giuliani, G., … Rovati, L. (2015). Correction: Wound healing properties of hyaluronan derivatives bearing ferulate residues. Journal of Materials Chemistry B, 3(36), 7307–7307. https://doi.org/10.1039/C5TB90126J

Cervellati, C., Sticozzi, C., Romani, A., Belmonte, G., De Rasmo, D., Signorile, A., … Valacchi, G. (2015). Impaired enzymatic defensive activity, mitochondrial dysfunction and proteasome activation are involved in RTT cell oxidative damage. Biochimica Et Biophysica Acta (BBA) - Molecular Basis of Disease, 1852(10), 2066–2074. https://doi.org/10.1016/J.BBADIS.2015.07.014

Pecorelli, A., Natrella, F., Belmonte, G., Miracco, C., Cervellati, F., Ciccoli, L., … Valacchi, G. (2015). NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy. Biochimica Et Biophysica Acta (BBA) - Molecular Basis of Disease, 1852(3), 507–519. https://doi.org/10.1016/J.BBADIS.2014.11.016

Torricelli, C., Daveri, E., Salvadori, S., Valacchi, G., Ietta, F., Muscettola, M., … Maioli, E. (2015). Phosphorylation-independent mTORC1 inhibition by the autophagy inducer Rottlerin. Cancer Letters, 360(1), 17–27. https://doi.org/10.1016/J.CANLET.2015.01.040

Pessina, F., Capasso, R., Borrelli, F., Aveta, T., Buono, L., Valacchi, G., … Izzo, A. A. (2015). Protective Effect of Palmitoylethanolamide in a Rat Model of Cystitis. Journal of Urology, 193(4), 1401–1408. https://doi.org/10.1016/J.JURO.2014.11.083

Kousha, T., & Valacchi, G. (2015). The Air Quality Health Index and Emergency Department Visits for Urticaria in Windsor, Canada. Journal of Toxicology and Environmental Health, Part A, 78(8), 524–533. https://doi.org/10.1080/15287394.2014.991053

Cheleschi, S., Valacchi, G., Pascarelli, N. A., Di Capua, A., Belmonte, G., Giordani, A., … Sticozzi, C. (2015). The effects of three different classes of anti-inflammatory agents on in vitro human osteoarthritic chondrocytes exposed to IL-1β. Osteoarthritis and Cartilage, 23, A159–A160. https://doi.org/10.1016/J.JOCA.2015.02.917

Valacchi, G., Grisci, G., Sticozzi, C., Lim, Y., Paolino, M., Giuliani, G., … Rovati, L. (2015). Wound healing properties of hyaluronan derivatives bearing ferulate residues. Journal of Materials Chemistry B, 3(35), 7037–7045. https://doi.org/10.1039/C5TB00661A

Signorini, C., De Felice, C., Leoncini, S., Durand, T., Galano, J.-M., Cortelazzo, A., … Hayek, J. (2014). Altered erythrocyte membrane fatty acid profile in typical Rett syndrome: Effects of omega-3 polyunsaturated fatty acid supplementation. Prostaglandins, Leukotrienes and Essential Fatty Acids, 91(5), 183–193. https://doi.org/10.1016/J.PLEFA.2014.08.002

Cervellati, F., Muresan, X. M., Sticozzi, C., Gambari, R., Montagner, G., Forman, H. J., … Valacchi, G. (2014). Comparative effects between electronic and cigarette smoke in human keratinocytes and epithelial lung cells. Toxicology in Vitro, 28(5), 999–1005. https://doi.org/10.1016/J.TIV.2014.04.012

Esposito, E., Ravani, L., Mariani, P., Huang, N., Boldrini, P., Drechsler, M., … Puglia, C. (2014). Effect of nanostructured lipid vehicles on percutaneous absorption of curcumin. European Journal of Pharmaceutics and Biopharmaceutics, 86(2), 121–132. https://doi.org/10.1016/J.EJPB.2013.12.011

De Felice, C., Della Ragione, F., Signorini, C., Leoncini, S., Pecorelli, A., Ciccoli, L., … D'Esposito, M. (2014). Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome. Neurobiology of Disease, 68, 66–77. https://doi.org/10.1016/J.NBD.2014.04.006

Cortelazzo, A., Lampariello, R. L., Sticozzi, C., Guerranti, R., Mirasole, C., Zolla, L., … Valacchi, G. (2014). Proteomic profiling and post-translational modifications in human keratinocytes treated with Mucuna pruriens leaf extract. Journal of Ethnopharmacology, 151(2), 873–881. https://doi.org/10.1016/J.JEP.2013.11.053

Sticozzi, C., Cervellati, F., Muresan, X. M., Cervellati, C., & Valacchi, G. (2014). Resveratrol prevents cigarette smoke-induced keratinocytes damage. Food & Function, 5(9), 2348. https://doi.org/10.1039/C4FO00407H

Tyrovolas, S., Haro, J. M., Mariolis, A., Piscopo, S., Valacchi, G., Tsakountakis, N., … Panagiotakos, D. (2014). Successful aging, dietary habits and health status of elderly individuals: A k-dimensional approach within the multi-national MEDIS study. Experimental Gerontology, 60, 57–63. https://doi.org/10.1016/J.EXGER.2014.09.010

Sticozzi, C., Belmonte, G., Cervellati, F., Di Capua, A., Maioli, E., Cappelli, A., … Valacchi, G. (2013). Antiproliferative effect of two novel COX-2 inhibitors on human keratinocytes. European Journal of Pharmaceutical Sciences, 49(2), 133–141. https://doi.org/10.1016/J.EJPS.2013.02.009

Durand, T., De Felice, C., Signorini, C., Oger, C., Bultel-Poncé, V., Guy, A., … Hayek, J. (2013). F2-Dihomo-isoprostanes and brain white matter damage in stage 1 Rett syndrome. Biochimie, 95(1), 86–90. https://doi.org/10.1016/j.biochi.2012.09.017

Scalia, S., Trotta, V., Traini, D., Young, P. M., Sticozzi, C., Cervellati, F., & Valacchi, G. (2013). Incorporation of quercetin in respirable lipid microparticles: Effect on stability and cellular uptake on A549 pulmonary alveolar epithelial cells. Colloids and Surfaces B: Biointerfaces, 112, 322–329. https://doi.org/10.1016/J.COLSURFB.2013.07.067

Pecorelli, A., Bocci, V., Acquaviva, A., Belmonte, G., Gardi, C., Virgili, F., … Valacchi, G. (2013). NRF2 activation is involved in ozonated human serum upregulation of HO-1 in endothelial cells. Toxicology and Applied Pharmacology, 267(1), 30–40. https://doi.org/10.1016/j.taap.2012.12.001

Pecorelli, A., Leoncini, S., De Felice, C., Signorini, C., Cerrone, C., Valacchi, G., … Hayek, J. (2013). Non-protein-bound iron and 4-hydroxynonenal protein adducts in classic autism. Brain and Development, 35(2), 146–154. https://doi.org/10.1016/j.braindev.2012.03.011

Valacchi, G., Zanardi, I., Lim, Y., Belmonte, G., Miracco, C., Sticozzi, C., … Travagli, V. (2013). Ozonated oils as functional dermatological matrices: Effects on the wound healing process using SKH1 mice. International Journal of Pharmaceutics, 458(1), 65–73. https://doi.org/10.1016/J.IJPHARM.2013.09.039

Sticozzi, C., Belmonte, G., Pecorelli, A., Cervellati, F., Leoncini, S., Signorini, C., … Valacchi, G. (2013). Scavenger receptor B1 post-translational modifications in Rett syndrome. FEBS Letters, 587(14), 2199–2204. https://doi.org/10.1016/J.FEBSLET.2013.05.042

Sticozzi, C., Pecorelli, A., Lim, Y., Maioli, E., Pagnin, E., Davis, P. A., & Valacchi, G. (2012). Modulation of skin oxidative stress and inflammatory markers by environmental stressors. Differences between young and old. Journal of Dermatological Science, 65(3), 226–228. https://doi.org/10.1016/j.jdermsci.2011.11.004

Ciccoli, L., De Felice, C., Paccagnini, E., Leoncini, S., Pecorelli, A., Signorini, C., … Hayek, J. (2012). Morphological changes and oxidative damage in Rett Syndrome erythrocytes. Biochimica Et Biophysica Acta (BBA) - General Subjects, 1820(4), 511–520. https://doi.org/10.1016/j.bbagen.2011.12.002

De Felice, C., Signorini, C., Durand, T., Ciccoli, L., Leoncini, S., D’Esposito, M., … Hayek, J. (2012). Partial rescue of Rett syndrome by ω-3 polyunsaturated fatty acids (PUFAs) oil. Genes & Nutrition, 7(3), 447–458. https://doi.org/10.1007/S12263-012-0285-7

Lampariello, L. R., Cortelazzo, A., Guerranti, R., Sticozzi, C., & Valacchi, G. (2012). The Magic Velvet Bean of Mucuna pruriens. Journal of Traditional and Complementary Medicine, 2(4), 331–339. https://doi.org/10.1016/S2225-4110(16)30119-5

Valacchi, G., Davis, P. A., Khan, E. M., Lanir, R., Maioli, E., Pecorelli, A., … Goldkorn, T. (2011). Cigarette smoke exposure causes changes in Scavenger Receptor B1 level and distribution in lung cells. The International Journal of Biochemistry & Cell Biology, 43(7), 1065–1070. https://doi.org/10.1016/j.biocel.2009.05.014

Signorini, C., De Felice, C., Leoncini, S., Giardini, A., D'Esposito, M., Filosa, S., … Hayek, J. (2011). F4-neuroprostanes mediate neurological severity in Rett syndrome. Clinica Chimica Acta, 412(15-16), 1399–1406. https://doi.org/10.1016/j.cca.2011.04.016

Pecorelli, A., Ciccoli, L., Signorini, C., Leoncini, S., Giardini, A., D'Esposito, M., … Valacchi, G. (2011). Increased levels of 4HNE-protein plasma adducts in Rett syndrome. Clinical Biochemistry, 44(5-6), 368–371. https://doi.org/10.1016/j.clinbiochem.2011.01.007

Jang, S., Lim, Y., Valacchi, G., Sorn, S., Park, H., Park, N.-Y., & Lee, M. (2011). Preventive effects of protopanaxadiol and protopanaxatriol ginsenosides on liver inflammation and apoptosis in hyperlipidemic apoE KO mice. Genes & Nutrition, 7(2), 319–329. https://doi.org/10.1007/S12263-011-0245-7

De Luca, C., Scordo, M. G., Cesareo, E., Pastore, S., Mariani, S., Maiani, G., … Korkina, L. G. (2010). Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes. Toxicology and Applied Pharmacology, 248(3), 285–292. https://doi.org/10.1016/j.taap.2010.04.017

Torricelli, C., Valacchi, G., & Maioli, E. (2010). Novel PKCs activate ERK through PKD1 in MCF-7 cells. In Vitro Cellular & Developmental Biology - Animal, 47(1), 73–81. https://doi.org/10.1007/S11626-010-9355-6

Aldinucci, C., Maiorca, S. M., De Rosa, P., Palmi, M., Sticozzi, C., Ciccoli, L., … Pessina, G. P. (2010). The Physiological Behaviour of IMR-32 Neuroblastoma Cells is Affected by a 12-h Hypoxia/24-h Reoxygenation Period. Neurochemical Research, 35(11), 1691–1699. https://doi.org/10.1007/S11064-010-0231-2

Mencarelli, M., Pecorelli, A., Carbotti, P., Valacchi, G., Grasso, G., & Muscettola, M. (2009). Endothelin receptor A expression in human inflammatory cells. Regulatory Peptides, 158(1-3), 1–5. https://doi.org/10.1016/j.regpep.2009.06.004

Castagna, R., Davis, P. A., Vasu, V. T., Soucek, K., Cross, C. E., Greci, L., & Valacchi, G. (2009). Nitroxide radical TEMPO reduces ozone-induced chemokine IL-8 production in lung epithelial cells. Toxicology in Vitro, 23(3), 365–370. https://doi.org/10.1016/j.tiv.2008.12.016

Fortino, V., Torricelli, C., Capurro, E., Sacchi, G., Valacchi, G., & Maioli, E. (2008). Antiproliferative and Survival Properties of PMA in MCF-7 Breast Cancer Cell. Cancer Investigation, 26(1), 13–21. https://doi.org/10.1080/07357900701637949

Aung, H. H., Vasu, V. T., Valacchi, G., Corbacho, A. M., Kota, R. S., Lim, Y., … Gohil, K. (2008). Effects of dietary carotenoids on mouse lung genomic profiles and their modulatory effects on short-term cigarette smoke exposures. Genes & Nutrition, 4(1). https://doi.org/10.1007/S12263-008-0108-Z

Torricelli, C., Fortino, V., Capurro, E., Valacchi, G., Pacini, A., Muscettola, M., … Maioli, E. (2008). Rottlerin inhibits the nuclear factor κB/Cyclin-D1 cascade in MCF-7 breast cancer cells. Life Sciences, 82(11-12), 638–643. https://doi.org/10.1016/j.lfs.2007.12.020

Lim, Y., Vasu, V. T., Valacchi, G., Leonard, S., Hnin Aung, H., Schock, B. C., … Cross, C. E. (2008). Severe Vitamin E deficiency modulates airway allergic inflammatory responses in the murine asthma model. Free Radical Research, 42(4), 387–396. https://doi.org/10.1080/10715760801976600

Fortino, V., Maioli, E., Torricelli, C., Davis, P., & Valacchi, G. (2007). Cutaneous MMPs are differently modulated by environmental stressors in old and young mice. Toxicology Letters, 173(2), 73–79. https://doi.org/10.1016/j.toxlet.2007.06.004

Valacchi, G., Vasu, V., Yokohama, W., Corbacho, A., Phung, A., Lim, Y., … Davis, P. (2007). Lung vitamin E transport processes are affected by both age and environmental oxidants in mice☆. Toxicology and Applied Pharmacology, 222(2), 227–234. https://doi.org/10.1016/j.taap.2007.04.010

Lim, Y., Phung, A. D., Corbacho, A. M., Aung, H. H., Maioli, E., Reznick, A. Z., … Valacchi, G. (2006). Modulation of cutaneous wound healing by ozone: Differences between young and aged mice. Toxicology Letters, 160(2), 127–134. https://doi.org/10.1016/j.toxlet.2005.06.013

Schock, B. C., Van der Vliet, A., Corbacho, A. M., Leonard, S. W., Finkelstein, E., Valacchi, G., … Traber, M. G. (2004). Enhanced inflammatory responses in α-tocopherol transfer protein null mice. Archives of Biochemistry and Biophysics, 423(1), 162–169. https://doi.org/10.1016/j.abb.2003.12.009