Works (5)

Updated: April 3rd, 2024 17:01

2024 journal article

Myeloid cell MHC I expression drives CD8<SUP>+</SUP> T cell activation in nonalcoholic steatohepatitis

FRONTIERS IN IMMUNOLOGY, 14.

By: V. Adams n, L. Collins n, T. Williams n, J. Holmes n, P. Hess n, H. Atkins n, G. Scheidemantle n, X. Liu n ...

Contributors: T. Williams n, V. Adams n, L. Collins n, J. Holmes n, P. Hess n, H. Atkins n, G. Scheidemantle n, X. Liu n ...

Ed(s): T. Williams n, L. Collins n & A. Kennedy n

author keywords: liver; NASH; fibrosis; H2Kb; CD8(+) T cells; immunopeptidome
TL;DR: Activated hepatic CD8+ T cells are dependent on myeloid cell MHC class I expression in diet induced NASH to promote inflammation and fibrosis and a role of NADPH oxidase in the production of Ncf2 peptide generation is suggested. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 28, 2024

2023 journal article

High-dose paclitaxel and its combination with CSF1R inhibitor in polymeric micelles for chemoimmunotherapy of triple negative breast cancer

NANO TODAY, 51.

By: C. Lim*, D. Hwang*, M. Yazdimamaghani*, H. Atkins n, H. Hyun*, Y. Shin*, J. Ramsey*, P. Raedler ...

author keywords: High -dose therapy; Polymeric micelle; Chemoimmunotherapy; TNBC model
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: July 10, 2023

2023 journal article

Role of the protease-activated receptor-2 (PAR2) in the exacerbation of house dust mite-induced murine allergic lung disease by multi-walled carbon nanotubes

PARTICLE AND FIBRE TOXICOLOGY, 20(1).

By: H. Lee n, D. You n, A. Taylor-Just n, L. Tisch n, R. Bartone n, H. Atkins n, L. Ralph*, S. Antoniak*, J. Bonner n

author keywords: Carbon nanotubes; Allergens; Protease-activated receptor 2; Lung; Inflammation; Fibrosis
TL;DR: This study indicates that protease-activated receptor 2 (PAR2) mediates airway fibrosis but not eosinophilic lung inflammation induced by co-exposure to MWCNTs and HDM allergens. (via Semantic Scholar)
Source: Web Of Science
Added: August 28, 2023

2023 journal article

Unique Presentations of Burkholderia gladioli Infections in Several Strains of Immunocompromised Mice

COMPARATIVE MEDICINE, 73(5), 391–397.

By: A. Osborne*, S. Clark*, T. Whitcomb*, P. Devlin*, M. Lanza* & H. Atkins n

TL;DR: After completing systematic testing of the environment, failure of the water autoclavecycle was suspected as the cause of the outbreak and individually ventilated racks were sanitized and new breeders were purchased; these actions dramatically reduced B. gladioli infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: February 12, 2024

2022 article

Pulmonary exposure of mice to ammonium perfluoro(2-methyl-3-oxahexanoate) (GenX) suppresses the innate immune response to carbon black nanoparticles and stimulates lung cell proliferation

Lee, H. Y., You, D. J., Taylor-Just, A. J., Linder, K. E., Atkins, H. M., Ralph, L. M., … Bonner, J. C. (2022, June 14). INHALATION TOXICOLOGY.

By: H. Lee n, D. You n, A. Taylor-Just n, K. Linder n, H. Atkins n, L. Ralph*, G. Cruz*, J. Bonner n

author keywords: Carbon black; nanoparticles; PFAS; lung; immunity
MeSH headings : Ammonium Compounds / toxicity; Animals; Bronchoalveolar Lavage Fluid / chemistry; Cell Proliferation; Cytokines / metabolism; Fluorocarbons / toxicity; Immunity, Innate; Ki-67 Antigen / metabolism; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B / metabolism; Nanoparticles / toxicity; Soot / toxicity
TL;DR: Pulmonary exposure to GenX suppressed CBNP-induced innate immune response in the lungs of mice yet promoted the proliferation of macrophages and lung epithelial cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 27, 2022

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