Heath Ellis Johnson
Works (8)
Updated: August 17th, 2023 21:16
2016 journal article
Are Filopodia Privileged Signaling Structures in Migrating Cells?
BIOPHYSICAL JOURNAL, 111(9), 1827–1830.
MeSH headings : Animals; Cell Movement; Mice; NIH 3T3 Cells; Optical Imaging; Pseudopodia / metabolism; Signal Transduction
europepmc.org (repository)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Lamellipodia are crucial for haptotactic sensing and response
JOURNAL OF CELL SCIENCE, 129(12), 2329–2342.
author keywords: Haptotaxis; Arp2/3; Lamellipodia; Directed migration
MeSH headings : Actin-Related Protein 2-3 Complex / metabolism; Actins / metabolism; Animals; Chemotaxis / drug effects; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Fibronectins / pharmacology; Focal Adhesion Protein-Tyrosine Kinases / metabolism; Focal Adhesions / metabolism; Guanine Nucleotide Exchange Factors / metabolism; Integrin beta1 / metabolism; Mice; Models, Biological; Pseudopodia / metabolism; Signal Transduction / drug effects; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Wiskott-Aldrich Syndrome Protein / metabolism; Wiskott-Aldrich Syndrome Protein Family / metabolism; rac GTP-Binding Proteins / metabolism; src-Family Kinases / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling
JOURNAL OF CELL BIOLOGY, 208(4), 443–455.
MeSH headings : 3T3 Cells; Actin Cytoskeleton; Actin-Related Protein 2-3 Complex / genetics; Actin-Related Protein 2-3 Complex / metabolism; Actins / physiology; Animals; Cell Adhesion / physiology; Cell Line; Cell Shape; Chemotaxis / genetics; Chemotaxis / physiology; Fibroblasts / cytology; Fibronectins / metabolism; Focal Adhesion Protein-Tyrosine Kinases / metabolism; Mice; Microfilament Proteins / biosynthesis; Microfilament Proteins / genetics; Microscopy, Fluorescence; Molecular Sequence Data; Phosphatidylinositol 3-Kinases / metabolism; Platelet-Derived Growth Factor / metabolism; Pseudopodia / physiology; RNA Interference; RNA, Small Interfering; Receptors, Odorant / biosynthesis; Receptors, Odorant / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
GMF beta controls branched actin content and lamellipodial retraction in fibroblasts
JOURNAL OF CELL BIOLOGY, 209(6), 803–812.
MeSH headings : Actin-Related Protein 2-3 Complex / antagonists & inhibitors; Actin-Related Protein 2-3 Complex / metabolism; Actins / biosynthesis; Animals; Cell Line; Cell Movement / physiology; Enzyme Activation; Fibroblasts / physiology; Fibronectins / pharmacology; Glia Maturation Factor / physiology; Indoles / pharmacology; Mice; Protein Isoforms / biosynthesis; Pseudopodia / physiology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways
DEVELOPMENTAL CELL, 32(1), 54–67.
MeSH headings : Actin Cytoskeleton / metabolism; Actin-Related Protein 2-3 Complex / metabolism; Actins / metabolism; Animals; Female; Fetal Proteins; Fibroblasts / cytology; Formins; Image Processing, Computer-Assisted; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microscopy, Fluorescence; Nuclear Proteins; Profilins / metabolism; Signal Transduction; Stress Fibers
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Mesenchymal Chemotaxis Requires Selective Inactivation of Myosin II at the Leading Edge via a Noncanonical PLC gamma/PKC alpha Pathway
DEVELOPMENTAL CELL, 31(6), 747–760.
MeSH headings : Animals; Cell Line; Cell Movement; Chemotaxis / physiology; Diglycerides / chemistry; Green Fluorescent Proteins / metabolism; Humans; Ligands; Mesoderm / physiology; Mice; Mice, Transgenic; Myosin Type II / metabolism; Phorbol Esters; Phospholipase C gamma / metabolism; Phosphorylation; Platelet-Derived Growth Factor / metabolism; Protein Kinase C-alpha / metabolism; Signal Transduction
Sources: Web Of Science, ORCID
Added: August 6, 2018
2013 journal article
Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility
MOLECULAR BIOLOGY OF THE CELL, 24(24), 3945–3955.
MeSH headings : Actin Cytoskeleton; Actins / metabolism; Actomyosin / physiology; Animals; Cell Adhesion / physiology; Cell Adhesion Molecules / genetics; Cell Movement / physiology; Computer Simulation; Extracellular Matrix / metabolism; Focal Adhesions / physiology; Integrins / genetics; Integrins / metabolism; Integrins / physiology; Mechanotransduction, Cellular; Myosin Type II / metabolism; Pseudopodia / metabolism; Signal Transduction / genetics; rhoA GTP-Binding Protein / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism
JOURNAL OF CELL BIOLOGY, 197(1), 105–114.
MeSH headings : Animals; Cell Movement; Cells, Cultured; Fibroblasts / cytology; Fibroblasts / enzymology; Fibroblasts / metabolism; Mice; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases / metabolism; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018
