Hrvoje Lusic

Works (17)

Updated: July 6th, 2023 21:22
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2013 journal article

Cellular Delivery and Photochemical Activation of Antisense Agents through a Nucleobase Caging Strategy

ACS CHEMICAL BIOLOGY, 8(10), 2272–2282.

By: J. Govan n, R. Uprety n, M. Thomas  n, H. Lusic n, M. Lively* & A. Deiters n

MeSH headings : Base Sequence; Gene Transfer Techniques; HeLa Cells; Humans; Light; Models, Biological; Molecular Structure; Oligonucleotides, Antisense / chemistry; Oligonucleotides, Antisense / genetics; Oligonucleotides, Antisense / metabolism; Polymerase Chain Reaction; tat Gene Products, Human Immunodeficiency Virus / chemistry; tat Gene Products, Human Immunodeficiency Virus / genetics
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Optochemical control of RNA interference in mammalian cells

NUCLEIC ACIDS RESEARCH, 41(22), 10518–10528.

By: J. Govan*, D. Young *, H. Lusic n, Q. Liu  n, M. Lively* & A. Deiters n

Source: Web Of Science
Added: August 6, 2018

2011 journal article

A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos

Development, 139(2), 437–442.

By: A. Morckel n, H. Lusic n, L. Farzana n, J. Yoder n , A. Deiters n & N. Nascone-Yoder n

author keywords: Small-molecule inhibitor; Rho kinase; Photocaging; Xenopus
MeSH headings : Animals; Body Patterning / drug effects; Dioxoles / metabolism; Dioxoles / pharmacology; Embryo, Nonmammalian / metabolism; Immunohistochemistry; Indoles / metabolism; Indoles / pharmacology; Mice; NIH 3T3 Cells; Pyridines / metabolism; Pyridines / pharmacology; Ultraviolet Rays; Xenopus laevis / embryology; Xenopus laevis / metabolism; rho-Associated Kinases / antagonists & inhibitors; rho-Associated Kinases / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

The Human Mitochondrial tRNA(Met): Structure/Function Relationship of a Unique Modification in the Decoding of Unconventional Codons

JOURNAL OF MOLECULAR BIOLOGY, 406(2), 257–274.

By: Y. Bilbille n, E. Gustilo n, K. Harris  n, C. Jones*, H. Lusic n, R. Kaiser*, M. Delano, L. Spremulli*, A. Deiters n, P. Agris  n

author keywords: 5-formylcytidine; NMR structure; mitochondrial translation; codon expansion; near cognate decoding
MeSH headings : Animals; Anticodon / chemistry; Anticodon / genetics; Base Pairing; Base Sequence; Cattle; Cytidine / analogs & derivatives; Cytidine / chemistry; Cytidine / genetics; Escherichia coli / genetics; Humans; Mitochondria / chemistry; Mitochondria / genetics; Molecular Sequence Data; RNA, Transfer, Met / chemistry; RNA, Transfer, Met / genetics; Ribosomes / chemistry; Ribosomes / genetics; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Generating Permissive Site-Specific Unnatural Aminoacyl-tRNA Synthetases

BIOCHEMISTRY, 49(8), 1667–1677.

By: S. Miyake-Stoner *, C. Refakis*, J. Hammill *, H. Lusic n, J. Hazen*, A. Deiters n, R. Mehl *

MeSH headings : Amino Acids / chemistry; Amino Acids / metabolism; Amino Acyl-tRNA Synthetases / chemistry; Amino Acyl-tRNA Synthetases / genetics; Amino Acyl-tRNA Synthetases / metabolism; Fluorine / chemistry; Green Fluorescent Proteins / chemistry; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Protein Engineering; Substrate Specificity
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Genetically encoded photocontrol of protein localization in mammalian cells

Journal of the American Chemical Society, 132(12), 4086-.

By: A. Gautier, D. Nguyen, H. Lusic, W. An, A. Deiters & J. Chin

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Improved Synthesis of the Two-Photon Caging Group 3-Nitro-2-Ethyldibenzofuran and Its Application to a Caged Thymidine Phosphoramidite

ORGANIC LETTERS, 12(5), 916–919.

By: H. Lusic n, R. Uprety n & A. Deiters n

MeSH headings : Benzofurans / chemical synthesis; Benzofurans / chemistry; DNA / chemical synthesis; DNA / chemistry; Organophosphorus Compounds / chemistry; Photons; Thymidine Monophosphate / analogs & derivatives; Thymidine Monophosphate / chemistry
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Photocaged Morpholino Oligomers for the Light-Regulation of Gene Function in Zebrafish and Xenopus Embryos

Journal of the American Chemical Society, 132(44), 15644–15650.

By: A. Deiters n, R. Garner n, H. Lusic n, J. Govan n, M. Dush n, N. Nascone-Yoder n, J. Yoder n 

MeSH headings : Animals; Cells, Cultured; Embryo, Nonmammalian / metabolism; Gene Expression; Morpholines / chemistry; Oligonucleotides / genetics; Oligonucleotides / metabolism; Ultraviolet Rays; Xenopus laevis / genetics; Xenopus laevis / metabolism; Zebrafish / genetics; Zebrafish / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2010 journal article

Photocleavable Polyethylene Glycol for the Light-Regulation of Protein Function

BIOCONJUGATE CHEMISTRY, 21(8), 1404–1407.

By: W. Georgianna n, H. Lusic n, A. Mclver & A. Deiters n

MeSH headings : Crystallography, X-Ray; Models, Molecular; Molecular Structure; Muramidase / chemistry; Muramidase / metabolism; Photochemical Processes; Polyethylene Glycols / chemical synthesis; Polyethylene Glycols / chemistry; Stereoisomerism; Ultraviolet Rays
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteins via a Pyrrolysyl-tRNA Synthetase/tRNA(CUA) Pair and Click Chemistry

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(25), 8720-+.

By: D. Nguyen *, H. Lusic n, H. Neumann  n, P. Kapadnis n, A. Deiters n & J. Chin  n

MeSH headings : Alkynes / chemistry; Alkynes / metabolism; Amino Acyl-tRNA Synthetases / genetics; Amino Acyl-tRNA Synthetases / metabolism; Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Azides / chemistry; Azides / metabolism; Escherichia coli / genetics; Escherichia coli Proteins / chemistry; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Lysine / chemistry; Lysine / genetics; Lysine / metabolism; Methanosarcina barkeri / enzymology; Myoglobin / chemistry; Myoglobin / genetics; Myoglobin / metabolism; Protein Engineering / methods; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization

Nucleic Acids Research, 37(8).

By: D. Young, H. Lusic, M. Lively & A. Deiters

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Gene Silencing in Mammalian Cells with Light-Activated Antisense Agents

ChemBioChem, 9(18), 2937–2940.

By: D. Young n, H. Lusic n, M. Lively*, J. Yoder n  & A. Deiters n

author keywords: Antisense agents; caged compounds; DNA; gene regulation; RNA
MeSH headings : Animals; Base Sequence; Gene Silencing; Genes, Reporter; Light; Luciferases, Renilla / chemistry; Mice; NIH 3T3 Cells; Oligonucleotides, Antisense / chemistry; Oligonucleotides, Antisense / metabolism; Oligonucleotides, Antisense / radiation effects; Phosphorothioate Oligonucleotides / chemistry; Phosphorothioate Oligonucleotides / metabolism; Transfection
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Light-activated deoxyguanosine: photochemical regulation of peroxidase activity

MOLECULAR BIOSYSTEMS, 4(6), 508–511.

By: H. Lusic n, M. Lively* & A. Deiters n

MeSH headings : Biocatalysis / radiation effects; DNA, Catalytic / chemical synthesis; DNA, Catalytic / chemistry; DNA, Catalytic / radiation effects; Deoxyguanosine / chemical synthesis; Deoxyguanosine / chemistry; Deoxyguanosine / metabolism; Enzyme Activation / radiation effects; Molecular Structure; Organophosphorus Compounds / chemical synthesis; Organophosphorus Compounds / chemistry; Organophosphorus Compounds / metabolism; Peroxidase / metabolism; Photochemistry; Time Factors; Ultraviolet Rays
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Light-triggered polymerase chain reaction

CHEMICAL COMMUNICATIONS, (4), 462–464.

By: D. Young n, W. Edwards n, H. Lusic n, M. Lively* & A. Deiters n

MeSH headings : Base Sequence; DNA / chemistry; DNA Primers; Light; Photochemistry; Polymerase Chain Reaction / methods
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNA(Met)

NUCLEIC ACIDS RESEARCH, 36(20), 6548–6557.

By: H. Lusic n, E. Gustilo n, F. Vendeix n, R. Kaiser n, M. Delaney n, W. Graham n, V. Moye n, W. Cantara n, P. Agris n, A. Deiters n

MeSH headings : Anticodon / chemistry; Base Sequence; Codon / metabolism; Cytidine / analogs & derivatives; Cytidine / chemistry; Humans; Molecular Sequence Data; Nucleic Acid Conformation; Protein Biosynthesis; RNA / chemistry; RNA, Mitochondrial; RNA, Transfer, Met / chemical synthesis; RNA, Transfer, Met / chemistry; RNA, Transfer, Met / metabolism; Thermodynamics
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Photochemical DNA activation

ORGANIC LETTERS, 9(10), 1903–1906.

By: H. Lusic n, D. Young n, M. Lively n & A. Deiters n

MeSH headings : DNA, Catalytic / chemistry; DNA, Catalytic / metabolism; Molecular Sequence Data; Molecular Structure; Photochemistry; RNA / metabolism; Substrate Specificity
Source: Web Of Science
Added: August 6, 2018

2006 journal article

A new photocaging group for aromatic N-heterocycles

SYNTHESIS-STUTTGART, (13), 2147–2150.

By: H. Lusic* & A. Deiters*

author keywords: bioorganic chemistry; heterocycles; photocaging; protecting groups
Source: Web Of Science
Added: August 6, 2018