Hong Qian

Works (3)

Updated: July 5th, 2023 15:50

2010 journal article

Polymeric macroinitiators for signal amplification in AGET ATRP-based DNA detection

SENSORS AND ACTUATORS B-CHEMICAL, 150(2), 594–600.

By: H. Qian n & L. He n

author keywords: Polylysine (PLL); Macroinitiator; Activators generated by electron transfer for atom transfer radical polymerization; (AGET ATRP); DNA detection; Signal amplification
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; Polymer Surface Interaction Studies; DNA and Nucleic Acid Chemistry
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Source: Web Of Science
Added: August 6, 2018

2009 journal article

Detection of Protein Binding Using Activator Generated by Electron Transfer for Atom Transfer Radical Polymerization

ANALYTICAL CHEMISTRY, 81(23), 9824–9827.

By: H. Qian n & L. He n

MeSH headings : Animals; Cattle; Electron Transport; Immobilized Proteins / chemistry; Immobilized Proteins / metabolism; Polymers / chemistry; Protein Binding
topics (OpenAlex): Analytical Chemistry and Sensors; Conducting polymers and applications; Biosensors and Analytical Detection
TL;DR: A purge-free controlled living polymerization method, activator generated by electron transfer for atom transfer radical polymerization (AGET ATRP), is used to amplify the occurrence of protein binding events and detection of ovalbumin is demonstrated where binding of femtomole protein is differentiable from the background using ellipsometry. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Surface-Initiated Activators Generated by Electron Transfer for Atom Transfer Radical Polymerization in Detection of DNA Point Mutation

ANALYTICAL CHEMISTRY, 81(11), 4536–4542.

By: H. Qian n & L. He n

MeSH headings : Ascorbic Acid; Base Sequence; Biosensing Techniques / economics; Biosensing Techniques / methods; Catalysis; DNA / analysis; DNA / genetics; Nucleic Acid Hybridization / methods; Oxidation-Reduction; Point Mutation; Sensitivity and Specificity; Time Factors
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; Advanced Polymer Synthesis and Characterization; DNA and Nucleic Acid Chemistry
TL;DR: The employment of a purge-free controlled/"living" polymerization reaction, activators generated by electron transfer for atom transfer radical polymerization (AGET ATRP), to achieve signal amplification upon DNA hybridization substantiates the feasibility of using Amplification-by-Polymerization for high throughput or portable screening of genetic mutations. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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