Ismaeel Muhamed

Works (2)

Updated: July 5th, 2023 15:31

2021 journal article

Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses

Colloids and Surfaces B: Biointerfaces, 204, 111805.

By: C. Roosa n, I. Muhamed n, A. Young n, K. Nellenbach n, M. Daniele n , F. Ligler n, A. Brown n 

author keywords: Fibrin; Nanoparticles; Wound healing; Regenerative medicine; Fibrin sealant
MeSH headings : Fibrin; Fibrin Tissue Adhesive; Nanoparticles; Polymerization; Wound Healing
TL;DR: It is shown that SFBNs may be a promising wound healing therapy that can be easily produced and delivered in a flowable formulation and support cell migration in an in vitro angiogenic sprouting assay, relevant for wound healing. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: July 19, 2021

2019 journal article

Fibrin Nanoparticles Coupled with Keratinocyte Growth Factor Enhance the Dermal Wound-Healing Rate

ACS Applied Materials & Interfaces, 11(4), 3771–3780.

By: I. Muhamed n, E. Sproul n, F. Ligler n & A. Brown n 

author keywords: fibrin nanoparticles; tissue regeneration; cell migration; microfluidics; wound healing; biomaterials; cell migration; in vitro 3D wound model and in vivo dermal wound model
MeSH headings : Animals; Biocompatible Materials / chemistry; Cell Movement / drug effects; Fibrin / chemistry; Fibroblast Growth Factor 7 / chemistry; Fibroblast Growth Factor 7 / therapeutic use; Mice; Microfluidics; Nanoparticles / chemistry; Wound Healing / drug effects
TL;DR: FBNs described here are constructed from physiologically relevant fibrin concentrations that support new tissue and dermal wound scaffold formation when coupled with growth factors and can be potentially administered with other tissue-healing factors and inflammatory mediators to improve wound- healing outcomes. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 18, 2019

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