Works (3)
Updated: July 6th, 2023 21:18
2017 journal article
Disruption of Trim9 function abrogates macrophage motility in vivo
Journal of Leukocyte Biology, 102(6), 1371–1380.
author keywords: chemotaxis; zebrafish; leukocyte; ubiquitin
MeSH headings : Animals; Cell Movement / genetics; Cell Shape; Chemotaxis; Humans; Macrophages / cytology; Macrophages / metabolism; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Tripartite Motif Proteins / genetics; Tripartite Motif Proteins / metabolism; U937 Cells; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
topics (OpenAlex): Immune cells in cancer; Neuroinflammation and Neurodegeneration Mechanisms; interferon and immune responses
TL;DR:
It is demonstrated that Trim9 mediates cellular movement and migration in Mϕs as well as neurons, and is implicated in axonal migration, and found that M ϕ chemotaxis and cellular architecture are subsequently impaired in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes
Immunogenetics, 68(4), 295–312.
author keywords: Innate immunity; Immunoglobulin domain; Haplotype; Polymorphism; Immune receptor
MeSH headings : Animals; Gene Expression Regulation, Developmental; Genes, MHC Class I / genetics; Genes, MHC Class I / immunology; Genetic Linkage; Haplotypes; Immunity, Innate; Immunoglobulins / genetics; Lipids / genetics; Receptors, Immunologic / genetics; Receptors, Immunologic / immunology; Zebrafish / genetics; Zebrafish / growth & development; Zebrafish / immunology; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
topics (OpenAlex): Immune Cell Function and Interaction; Zebrafish Biomedical Research Applications; Aquaculture disease management and microbiota
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Neutralization of Mitochondrial Superoxide by Superoxide Dismutase 2 Promotes Bacterial Clearance and Regulates Phagocyte Numbers in Zebrafish
Infection and Immunity, 83(1), 430–440.
Ed(s): B. McCormick
MeSH headings : Animals; Immunity, Innate; Leukocyte Count; Macrophages / enzymology; Macrophages / immunology; Mitochondria / enzymology; Mitochondria / metabolism; Pseudomonas aeruginosa / immunology; Superoxide Dismutase / metabolism; Superoxides / metabolism; Zebrafish
topics (OpenAlex): Neuroinflammation and Neurodegeneration Mechanisms; Neutrophil, Myeloperoxidase and Oxidative Mechanisms; Immune Response and Inflammation
TL;DR:
The roles of SOD2 and mitochondrial ROS regulation in the zebrafish innate immune response to P. aeruginosa infection are described and the use of mitochondrion-targeted ROS scavengers as potential adjuvant therapies during severe infections is supported.
(via Semantic Scholar)
open access via iai.asm.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018