Works (133)

Updated: March 18th, 2024 08:22

2023 journal article

A LGR5 reporter pig model closely resembles human intestine for improved study of stem cells in disease

FASEB JOURNAL, 37(6).

By: C. Schaaf n, K. Polkoff n, A. Carter n, A. Stewart n, B. Sheahan n, J. Freund n, J. Ginzel*, J. Snyder* ...

co-author countries: United States of America 🇺🇸
author keywords: APC mutation; colorectal cancer; intestine; Lgr5; porcine; stem cell; transgenic large animal
MeSH headings : Humans; Swine; Animals; Mice; In Situ Hybridization, Fluorescence; Intestines; Stem Cells; Ileum; Colon; Coleoptera; Green Fluorescent Proteins / genetics; Receptors, G-Protein-Coupled / genetics
Sources: Web Of Science, ORCID
Added: June 12, 2023

2023 journal article

A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs and humans

NPJ REGENERATIVE MEDICINE, 8(1).

By: W. Zhang*, X. Wang*, G. Lanzoni, E. Wauthier*, S. Simpson n, J. Ezzell*, A. Allen*, C. Suitt ...

co-author countries: China 🇨🇳 Italy 🇮🇹 United States of America 🇺🇸
Source: Web Of Science
Added: August 21, 2023

2023 article

Adrenomedullin Stimulates Proliferation, Migration and Adhesion of Porcine Trophectoderm Cells Via CALCRL-AKT-TSC2-MTORC1 Cell Signaling Pathway

Liu, B., Paudel, S., Flowers, W. L., Piedrahita, J. A., & Wang, X. (2023, May). JOURNAL OF ANIMAL SCIENCE, Vol. 101.

By: B. Liu n, S. Paudel n, W. Flowers n, J. Piedrahita n & X. Wang n

co-author countries: United States of America 🇺🇸
author keywords: adrenomedullin; peri-implantation; pig conceptus
Sources: Web Of Science, ORCID
Added: March 4, 2024

2023 article

Structure-guided AAV capsid evolution strategies for enhanced CNS gene delivery

Gonzalez, T. J., Mitchell-Dick, A., Blondel, L. O., Fanous, M. M., Hull, J. A., Oh, D. K., … Asokan, A. (2023, September 21). NATURE PROTOCOLS.

By: T. Gonzalez*, A. Mitchell-Dick*, L. Blondel*, M. Fanous*, J. Hull*, D. Oh*, S. Moller-Tank*, R. Rivera*, J. Piedrahita n, A. Asokan*

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: October 16, 2023

2023 article

Uterine histotroph and conceptus development: III. Adrenomedullin stimulates proliferation, migration and adhesion of porcine trophectoderm cells via AKT-TSC2-MTOR cell signaling pathway

Liu, B., Paudel, S., Flowers, W. L., Piedrahita, J. A., & Wang, X. (2023, April 10). AMINO ACIDS, Vol. 4.

By: B. Liu n, S. Paudel n, W. Flowers n, J. Piedrahita n & X. Wang n

co-author countries: United States of America 🇺🇸
author keywords: Adrenomedullin; Trophectoderm cells; MTOR; Pigs; Implantation
MeSH headings : Pregnancy; Female; Swine; Animals; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Adrenomedullin / pharmacology; Signal Transduction; TOR Serine-Threonine Kinases / genetics; TOR Serine-Threonine Kinases / metabolism; Cell Proliferation; Sirolimus / pharmacology
Sources: Web Of Science, ORCID
Added: April 24, 2023

2022 journal article

Age- and Sex-Specific Joint Biomechanics in Response to Partial and Complete Anterior Cruciate Ligament Injury in the Porcine Model

JOURNAL OF ATHLETIC TRAINING, 57(9-10), 978–989.

By: D. Howe n, S. Cone n, J. Piedrahita n, J. Spang* & M. Fisher n

co-author countries: United States of America 🇺🇸
author keywords: knee; transection studies; sex factors
MeSH headings : Male; Female; Humans; Animals; Swine; Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament / physiology; Biomechanical Phenomena; Joint Instability; Knee Joint; Cadaver
Source: Web Of Science
Added: March 6, 2023

2022 journal article

Allogeneic and xenogeneic lymphoid reconstitution in a RAG2(-/-)IL2RG(y/-) severe combined immunodeficient pig: A preclinical model for intrauterine hematopoietic transplantation

FRONTIERS IN VETERINARY SCIENCE, 9.

By: R. Sper n, J. Proctor n, O. Lascina n, L. Guo n, K. Polkoff n, T. Kaeser n, S. Simpson n, L. Borst n ...

co-author countries: United States of America 🇺🇸
author keywords: severe combined immunodeficiency; pig; xenotransplantation; allotransplantation; hematopoietic; RAG2; IL2RG; transgenic
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 journal article

Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing

NATURE COMMUNICATIONS, 13(1).

By: T. Gonzalez*, K. Simon*, L. Blondel*, M. Fanous*, A. Roger*, M. Maysonet, G. Devlin*, T. Smith* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Dependovirus / metabolism; Gene Editing; Genetic Therapy; Genetic Vectors / genetics; Humans; Macaca / genetics; Mice; Swine; Transduction, Genetic
Source: Web Of Science
Added: October 17, 2022

2022 article

Donor Age and Time in Culture Affect Dermal Fibroblast Contraction in an In Vitro Hydrogel Model

Detwiler, A., Polkoff, K., Gaffney, L., Freytes, D. O., & Piedrahita, J. A. (2022, August 4). TISSUE ENGINEERING PART A.

By: A. Detwiler n, K. Polkoff n, L. Gaffney n, D. Freytes n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: cell proliferation; collagen; dermis; extracellular matrix; fibroblasts; hydrogels; skin; wound healing
MeSH headings : Adult; Infant, Newborn; Humans; Swine; Animals; Hydrogels / pharmacology; Reproducibility of Results; Wound Healing; Collagen / chemistry; Fibroblasts
Source: Web Of Science
Added: August 29, 2022

2022 journal article

LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis

SCIENTIFIC REPORTS, 12(1).

By: K. Polkoff n, N. Gupta n, A. Green n, Y. Murphy n, J. Chung n, K. Gleason n, S. Simpson*, D. Walker n, B. Collins n, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified; Biomarkers / metabolism; Hair Follicle / metabolism; Humans; Morphogenesis; Receptors, G-Protein-Coupled / genetics; Receptors, G-Protein-Coupled / metabolism; Skin; Stem Cells / metabolism; Swine
Source: Web Of Science
Added: June 20, 2022

2022 article

Multiscale Anisotropic Tissue Biofabrication via Bulk Acoustic Patterning of Cells and Functional Additives in Hybrid Bioinks

Chansoria, P., Asif, S., Gupta, N., Piedrahita, J., & Shirwaiker, R. A. (2022, January 27). ADVANCED HEALTHCARE MATERIALS, Vol. 1.

By: P. Chansoria n, S. Asif n, N. Gupta n, J. Piedrahita n & R. Shirwaiker n

co-author countries: United States of America 🇺🇸
author keywords: 3D cell patterning; biofabrication; bioprinting; GelMA; hybrid bioinks; standing bulk acoustic waves; ultrasound
MeSH headings : Acoustics; Anisotropy; Bioprinting; Gelatin / chemistry; Humans; Hydrogels / chemistry; Methacrylates; Printing, Three-Dimensional; Tissue Engineering; Tissue Scaffolds / chemistry
Sources: Web Of Science, ORCID
Added: February 7, 2022

2022 journal article

Ontogeny of cellular organization and LGR5 expression in porcine cochlea revealed using tissue clearing and 3D imaging

ISCIENCE, 25(8).

By: A. Moatti n, C. Li n, S. Sivadanam n, Y. Cai n, J. Ranta n, J. Piedrahita n, A. Cheng*, F. Ligler n, A. Greenbaum n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: December 19, 2022

2022 article

The use of autologous skeletal muscle progenitor cells for adjunctive treatment of presumptive urethral sphincter mechanism incompetence in female dogs

Vaden, S. L., Mathews, K. G., Yoo, J., Williams, J. K., Harris, T., Secoura, P., … Piedrahita, J. (2022, August 5). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 8.

By: S. Vaden n, K. Mathews n, J. Yoo*, J. Williams*, T. Harris n, P. Secoura n, J. Robertson n, K. Gleason n, H. Reynolds n, J. Piedrahita n

co-author countries: United States of America 🇺🇸

Contributors: J. Robertson n

author keywords: canine; regenerative medicine; stem cell; urinary incontinence
MeSH headings : Animals; Dog Diseases / surgery; Dogs; Female; Muscle, Skeletal; Stem Cells; Urethra / surgery; Urinary Incontinence / therapy; Urinary Incontinence / veterinary
Sources: Web Of Science, ORCID
Added: August 26, 2022

2021 journal article

Characterizing the Effects of Synergistic Thermal and Photo-Cross-Linking during Biofabrication on the Structural and Functional Properties of Gelatin Methacryloyl (GeIMA) Hydrogels

ACS BIOMATERIALS SCIENCE & ENGINEERING, 7(11), 5175–5188.

By: P. Chansoria n, S. Asif n, K. Polkoff n, J. Chung n, J. Piedrahita n & R. Shirwaiker n

co-author countries: United States of America 🇺🇸
author keywords: GelMA; thermo-reversible cross-linking; photo-cross-linking; biofabrication; tissue engineering; CryoSEM; qPCR
MeSH headings : Biocompatible Materials; Gelatin; Humans; Hydrogels; Methacrylates; Tissue Engineering
Sources: Web Of Science, ORCID
Added: November 29, 2021

2021 journal article

Patch grafting, strategies for transplantation of organoids into solid organs such as liver

BIOMATERIALS, 277.

By: W. Zhang*, G. Lanzoni*, H. Hani*, D. Overi*, V. Cardinale*, S. Simpson n, W. Pitman*, A. Allen* ...

co-author countries: China 🇨🇳 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Liver; Biliary tree; Stem/progenitors; Cell therapies; Grafting; Matrix-metalloproteinases (MMPs); Hyaluronans
MeSH headings : Animals; Cell Differentiation; Hepatocytes; Liver; Organoids; Stem Cells; Swine
Source: Web Of Science
Added: October 4, 2021

2021 article

Sex-specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model

Howe, D., Cone, S. G., Piedrahita, J. A., Collins, B., Fordham, L. A., Griffith, E. H., … Fisher, M. B. (2021, November 9). JOURNAL OF ORTHOPAEDIC RESEARCH.

By: D. Howe n, S. Cone n, J. Piedrahita n, B. Collins n, L. Fordham*, E. Griffith n, J. Spang*, M. Fisher n

co-author countries: United States of America 🇺🇸
author keywords: anterior cruciate ligament; knee; porcine model; skeletal growth
MeSH headings : Adolescent; Aged; Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Biomechanical Phenomena; Child; Female; Humans; Joint Instability; Knee Joint; Male; Swine; Tibia
Source: Web Of Science
Added: November 15, 2021

2020 article

Clinical xenotransplantation of the heart: At the watershed

Platt, J. L., Piedrahita, J. A., & Cascalho, M. (2020, August). JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol. 39, pp. 758–760.

By: J. Platt*, J. Piedrahita n & M. Cascalho*

co-author countries: France 🇫🇷 United States of America 🇺🇸
MeSH headings : Animals; Heart; Heart Transplantation; Primates; Swine; Transplantation, Heterologous
Source: Web Of Science
Added: August 10, 2020

2020 journal article

In Vitro Validation of Transgene Expression in Gene-Edited Pias Using CRISPR Transcriptional Activators

CRISPR JOURNAL, 3(5), 409–418.

By: K. Polkoff n, J. Chung n, S. Simpson*, K. Gleason n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified / genetics; CRISPR-Associated Protein 9 / genetics; CRISPR-Associated Protein 9 / metabolism; Cells, Cultured; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Editing / methods; Gene Expression; Nuclear Transfer Techniques; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / metabolism; Swine; Trans-Activators / genetics; Trans-Activators / metabolism; Transgenes
Source: Web Of Science
Added: November 24, 2020

2020 journal article

Joint laxity varies in response to partial and complete anterior cruciate ligament injuries throughout skeletal growth

JOURNAL OF BIOMECHANICS, 101.

By: S. Cone n, E. Lambeth n, J. Piedrahita n, J. Spang* & M. Fisher n

co-author countries: United States of America 🇺🇸
author keywords: Anterior cruciate ligament; Pediatric; Injury; Joint mechanics; Animal model
MeSH headings : Animals; Anterior Cruciate Ligament Injuries / complications; Biomechanical Phenomena; Female; Joint Instability / complications; Joint Instability / physiopathology; Rotation; Stifle / growth & development; Stifle / physiopathology; Swine
Source: Web Of Science
Added: March 23, 2020

2020 journal article

Three-dimensional imaging of intact porcine cochlea using tissue clearing and custom-built light-sheet microscopy

BIOMEDICAL OPTICS EXPRESS, 11(11), 6181–6196.

By: A. Moatti n, Y. Cai n, C. Li n, T. Sattler n, L. Edwards n, J. Piedrahita n, F. Ligler n, A. Greenbaum n

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: December 11, 2020

2019 journal article

200 Developing exosomes as a mediator for CRISPR/Cas-9 delivery

Reproduction, Fertility and Development, 31(1), 225.

By: N. Gupta n, K. Polkoff n, L. Qiao n, K. Cheng n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 21, 2020

2019 journal article

Biomechanical Function and Size of the Anteromedial and Posterolateral Bundles of the ACL Change Differently with Skeletal Growth in the Pig Model

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 477(9), 2161–2174.

By: S. Cone, E. Lambeth, H. Ru, L. Fordham, J. Piedrahita, J. Spang, M. Fisher

MeSH headings : Aging / physiology; Animals; Anterior Cruciate Ligament / physiology; Biomechanical Phenomena; Cadaver; Models, Animal; Musculoskeletal Development / physiology; Range of Motion, Articular / physiology; Rotation; Swine; Tibia / physiology; Torque
Source: Web Of Science
Added: February 17, 2020

2019 journal article

In Situ Joint Stiffness Increases During Skeletal Growth but Decreases Following Partial and Complete Anterior Cruciate Ligament Injury

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 141(12).

By: S. Cone n, J. Piedrahita n, J. Spang* & M. Fisher n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: January 27, 2020

2019 journal article

Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth

PLOS ONE, 14(10).

By: S. Cone n, H. Piercy n, E. Lambeth n, H. Ru n, J. Piedrahita n, J. Spang*, L. Fordham*, M. Fisher n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament / growth & development; Female; Knee Joint / diagnostic imaging; Knee Joint / growth & development; Magnetic Resonance Imaging; Organ Specificity; Patellar Ligament / diagnostic imaging; Patellar Ligament / growth & development; Swine
Source: Web Of Science
Added: June 8, 2020

2018 journal article

High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism

Proceedings of the National Academy of Sciences, 115(21), 5420–5425.

By: J. Chung n, X. Zhang n, B. Collins n, R. Sper n, K. Gleason n, S. Simpson n, S. Koh n, J. Sommer n ...

co-author countries: United States of America 🇺🇸
author keywords: HMGA2; dwarfism; swine; gene editing; organ size
MeSH headings : Animals; Cryptorchidism / etiology; Cryptorchidism / pathology; Dwarfism / etiology; Dwarfism / pathology; Female; Fetal Diseases / etiology; Fetal Diseases / pathology; Genotype; HMGA2 Protein / deficiency; HMGA2 Protein / genetics; Litter Size; Male; Nuclear Transfer Techniques / veterinary; Pregnancy; Reproduction; Swine; Swine Diseases / etiology; Swine Diseases / pathology
Sources: Web Of Science, Crossref
Added: August 6, 2018

2018 article

INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges

ILAR JOURNAL, Vol. 59, pp. 209–210.

By: G. Jungersen* & J. Piedrahita n

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸
author keywords: animal models; immunology; preclinical validity
MeSH headings : Allergy and Immunology; Animals; Disease Models, Animal; Inflammation
Source: Web Of Science
Added: December 2, 2019

2018 review

Xenotransplantation: Progress Along Paths Uncertain from Models to Application

[Review of ]. ILAR JOURNAL, 59(3), 286–308.

By: J. Platt*, M. Cascalho* & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: adaptive immunity; clinical xenotransplantation; gene editing; innate immunity; molecular incompatibility; nonhuman primate; reverse xenograft; transgenic pig; xenotransplantation; zoonosis
MeSH headings : Adaptive Immunity; Animals; Gene Editing / methods; Genetic Engineering; Heterografts; Humans; Immunity, Innate / physiology; Primates; Stem Cells / metabolism; Swine
Source: Web Of Science
Added: December 2, 2019

2017 journal article

Animal Models in Tissue Engineering. Part I

Tissue Engineering Part C: Methods, 23(11), 641–642.

By: J. Piedrahita n & J. Williams*

co-author countries: United States of America 🇺🇸
author keywords: animal models; tissue engineering; regenerative medicine
MeSH headings : Animals; CRISPR-Cas Systems / genetics; Mice; Models, Animal; Rats; Sus scrofa; Tissue Engineering / methods; Translational Research, Biomedical
Sources: Web Of Science, Crossref
Added: August 6, 2018

2017 journal article

Animal Models in Tissue Engineering. Part II

Tissue Engineering Part C: Methods, 23(12), 827–828.

By: J. Piedrahita n & J. Williams*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Models, Biological; Tissue Engineering / methods; Tissue Engineering / trends
Source: Crossref
Added: July 27, 2019

2017 journal article

Generation of LIF-independent induced pluripotent stem cells from canine fetal fibroblasts

Theriogenology, 92, 75–82.

By: N. Gonçalves, F. Bressan*, K. Roballo, F. Meirelles*, P. Xavier, H. Fukumasu, C. Williams n, M. Breen n ...

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: iPSC; Canine; Stem cells; Pluripotency; Cellular reprogramming
MeSH headings : Animals; Dogs; Fetus / cytology; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / physiology; Gene Expression Regulation / physiology; Leukemia Inhibitory Factor / pharmacology; Mice; Mice, Inbred BALB C; Mice, Nude; Pluripotent Stem Cells / physiology; Polymerase Chain Reaction / veterinary
Sources: Web Of Science, Crossref
Added: August 6, 2018

2017 journal article

Generation of a Stable Transgenic Swine Model Expressing a Porcine Histone 2B-eGFP Fusion Protein for Cell Tracking and Chromosome Dynamics Studies

PLOS ONE, 12(1), e0169242.

By: R. Sper n, S. Koh*, X. Zhang n, S. Simpson n, B. Collins n, J. Sommer n, R. Petters n, I. Caballero n, J. Platt*, J. Piedrahita n

co-author countries: United States of America 🇺🇸

Ed(s): I. Polejaeva

MeSH headings : Animals; Cell Tracking / methods; Chromosomes, Mammalian / genetics; Chromosomes, Mammalian / metabolism; Female; Green Fluorescent Proteins / biosynthesis; Green Fluorescent Proteins / genetics; Histones / biosynthesis; Histones / genetics; Male; Organisms, Genetically Modified / genetics; Organisms, Genetically Modified / metabolism; Recombinant Fusion Proteins / biosynthesis; Recombinant Fusion Proteins / genetics; Swine / genetics; Swine / metabolism
Source: Crossref
Added: July 27, 2019

2017 journal article

Improved Chondrogenic Potential and Proteomic Phenotype of Porcine Chondrocytes Grown in Optimized Culture Conditions

Cellular Reprogramming, 19(4), 232–244.

By: S. Koh n, M. Purser n, R. Wysk n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: chondrocytes; serum-free culture; low oxygen; pig; proteomics
MeSH headings : Animals; Cartilage / cytology; Cartilage / metabolism; Cell Culture Techniques / methods; Chondrocytes / cytology; Chondrocytes / metabolism; Chondrogenesis; Culture Media / chemistry; Extracellular Matrix Proteins / biosynthesis; Gene Expression Regulation; Swine
Source: Crossref
Added: July 27, 2019

2017 journal article

Orientation changes in the cruciate ligaments of the knee during skeletal growth: A porcine model

Journal of Orthopaedic Research, 35(12), 2725–2732.

By: S. Cone n, S. Simpson n, J. Piedrahita n, L. Fordham*, J. Spang* & M. Fisher n

co-author countries: United States of America 🇺🇸
author keywords: anterior cruciate ligament; posterior cruciate ligament; adolescent; porcine; MRI
MeSH headings : Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament / growth & development; Female; Magnetic Resonance Imaging; Posterior Cruciate Ligament / diagnostic imaging; Posterior Cruciate Ligament / growth & development; Swine
Sources: Crossref, Web Of Science
Added: August 6, 2018

2016 journal article

1 GENERATION OF A STABLE TRANSGENIC SWINE MODEL FOR CELL TRACKING AND CHROMOSOME DYNAMIC STUDIES

Reproduction, Fertility and Development, 28(2), 130.

By: R. Sper n, S. Simpson n, X. Zhang n, B. Collins n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2016 journal article

27 AN IMPROVED LARGE ANIMAL MODEL FOR THE STUDY OF ADULT STEM CELLS

Reproduction, Fertility and Development, 28(2), 143.

By: S. Simpson n, L. Gonzalez n, J. Chung n, A. Blikslager n, S. Magness n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2016 journal article

Effect of Plant Species, Fertilizer Acidity/Basicity, and Fertilizer Concentration on pH of Soilless Root Substrate

HORTSCIENCE, 51(12), 1596–1601.

By: K. Jeong, P. Nelson, C. Niedziela & D. Dickey

author keywords: alkalinity; electrical conductivity; root media
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Cardiac regenerative potential of cardiosphere-derived cells from adult dog hearts

Journal of Cellular and Molecular Medicine, 19(8), 1805–1813.

By: M. Hensley n, J. Andrade n, B. Keene n, K. Meurs n, J. Tang n, Z. Wang*, T. Caranasos*, J. Piedrahita n ...

co-author countries: China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
author keywords: cardiosphere-derived cells; dogs; dilated cardiomyopathy; stem cell therapy
MeSH headings : Aging; Animals; Apoptosis; Cell Differentiation; Cells, Cultured; Dogs; Female; Fibrosis; Heart / physiology; Heart Function Tests; Mice, SCID; Myocardium / pathology; Myocytes, Cardiac / cytology; Neovascularization, Physiologic; Paracrine Communication; Regeneration; Spheroids, Cellular / cytology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2015 journal article

Characterization of putative haematopoietic cells from bovine yolk sac

Journal of Tissue Engineering and Regenerative Medicine, 11(4), 1132–1140.

By: V. Oliveira*, C. Mançanares*, L. Oliveira*, N. Gonçalves*, M. Miglino*, F. Perecin*, F. Meirelles*, J. Piedrahita n, C. Ambrósio*

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: yolk sac; bovine; embryos; haematopoietic cell
MeSH headings : Animals; Cattle; Cell Adhesion / drug effects; Cell Survival / drug effects; Cells, Cultured; Colony-Forming Units Assay; Embryo, Mammalian / cytology; Female; Flow Cytometry; Hematopoietic Stem Cells / cytology; Hematopoietic Stem Cells / drug effects; Hematopoietic Stem Cells / ultrastructure; Methylcellulose / pharmacology; Polymerase Chain Reaction; Pregnancy; Yolk Sac / cytology
Source: Crossref
Added: January 21, 2021

2015 chapter

Generation of Induced Pluripotent Stem Cells (iPSCs) from Adult Canine Fibroblasts

In Methods in Molecular Biology (pp. 69–78).

By: S. Koh* & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cell Culture Techniques; Cell Differentiation; Cellular Reprogramming; Dogs; Feeder Cells; Fibroblasts / cytology; Fibroblasts / metabolism; Genetic Vectors / genetics; Induced Pluripotent Stem Cells / cytology; Induced Pluripotent Stem Cells / metabolism; Kruppel-Like Factor 4; Mice; Retroviridae / genetics; Transcription Factors / genetics; Transduction, Genetic; Transgenes
Source: Crossref
Added: July 28, 2019

2015 journal article

Intravenous Cardiac Stem Cell-Derived Exosomes Ameliorate Cardiac Dysfunction in Doxorubicin Induced Dilated Cardiomyopathy

Stem Cells International, 2015, 1–8.

By: A. Vandergriff n, J. de Andrade n, J. Tang n, M. Hensley n, J. Piedrahita n, T. Caranasos*, K. Cheng n

co-author countries: China 🇨🇳 United States of America 🇺🇸
Sources: Web Of Science, Crossref
Added: August 6, 2018

2014 journal article

5 DISRUPTION OF THE HIGH MOBILITY GROUP AT-HOOK 2 (HMGA2) GENE IN SWINE REDUCES POSTNATAL GROWTH

Reproduction, Fertility and Development, 26(1), 117.

By: J. Chung n, X. Zhang n, B. Colins n, K. Howard, S. Simpson n, C. Salmon, S. Koh n, R. Sper n, C. Byrd, J. Piedrahita n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2014 review

From "ES-like" cells to induced pluripotent stem cells: A historical perspective in domestic animals

[Review of ]. THERIOGENOLOGY, 81(1), 103–111.

By: S. Koh n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: Pluripotent stem cells; Reprogramming; Large animals; Induced pluripotent stem cells
MeSH headings : Animals; Animals, Domestic / embryology; Animals, Domestic / physiology; Cattle; Dogs; Embryonic Stem Cells; Genomic Instability; Induced Pluripotent Stem Cells; Regenerative Medicine; Swine / physiology
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Stem Cells and Regenerative Medicine in Domestic and Companion Animals: A Multispecies Perspective

Reproduction in Domestic Animals, 49, 2–10.

By: N. Gonçalves, C. Ambrósio & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Adult; Animals; Animals, Domestic / embryology; Cats; Dogs; Embryonic Stem Cells; Horses; Humans; Induced Pluripotent Stem Cells; Mice; Pets / embryology; Rats; Regenerative Medicine / trends; Stem Cells
Sources: Web Of Science, Crossref
Added: August 6, 2018

2013 journal article

Alternating Current Electric Fields of Varying Frequencies: Effects on Proliferation and Differentiation of Porcine Neural Progenitor Cells

Cellular Reprogramming, 15(5), 405–412.

By: J. Lim n, S. McCullen n, J. Piedrahita n, E. Loboa n & N. Olby n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Electricity; Electrodes; Fluorescence; Glial Fibrillary Acidic Protein / metabolism; Neural Stem Cells / cytology; Swine; Swine, Miniature; Tubulin / metabolism
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2013 journal article

Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration

PLoS One, 8(6).

By: L. Gonzalez, I. Williamson, J. Piedrahita, A. Blikslager & S. Magness

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Differences in X-Chromosome Transcriptional Activity and Cholesterol Metabolism between Placentae from Swine Breeds from Asian and Western Origins

PLOS ONE, 8(1).

By: S. Bischoff n, S. Tsai n, N. Hardison n, A. Motsinger-Reif n, B. Freking*, D. Nonneman*, G. Rohrer*, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cholesterol / metabolism; Computational Biology; Female; Fertility / physiology; Gene Expression Profiling / veterinary; Gestational Age; Linear Models; Microarray Analysis / veterinary; Placenta / metabolism; Placenta / physiology; Pregnancy; RNA, Long Noncoding / genetics; Real-Time Polymerase Chain Reaction / veterinary; Reverse Transcriptase Polymerase Chain Reaction / veterinary; Species Specificity; Swine / genetics; Swine / physiology; Transcription, Genetic / physiology; X Chromosome / genetics; X Chromosome / metabolism
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas

Placenta, 34(7), 599–605.

By: L. Guo n, S. Tsai*, N. Hardison n, A. James*, A. Motsinger-Reif n, B. Thames*, E. Stone n, C. Deng*, J. Piedrahita n

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: Placenta; Preeclampsia; IUGR; MiR-194; MiR-149
MeSH headings : Down-Regulation; Female; Fetal Growth Retardation / genetics; Fetal Growth Retardation / metabolism; Humans; MicroRNAs / biosynthesis; Placenta / metabolism; Pre-Eclampsia / genetics; Pre-Eclampsia / metabolism; Pregnancy; Transcriptome
Sources: Web Of Science, Crossref
Added: August 6, 2018

2013 journal article

Expression of antisense of insulin-like growth factor-2 receptor RNA non-coding (AIRN) during early gestation in cattle

Animal Reproduction Science, 138(1-2), 64–73.

By: W. Farmer n, P. Farin n, J. Piedrahita n, S. Bischoff n & C. Farin n

co-author countries: United States of America 🇺🇸
author keywords: Bovine; IGF2R; Antisense RNA; Embryo; Fetus
MeSH headings : Animals; Cattle / embryology; Embryo, Mammalian / metabolism; Female; Fertilization in Vitro / veterinary; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Developmental / physiology; Liver / metabolism; Male; Pregnancy; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA, Untranslated / genetics; Receptor, IGF Type 2 / genetics; Receptor, IGF Type 2 / metabolism; Reverse Transcriptase Polymerase Chain Reaction / veterinary
Sources: Crossref, Web Of Science
Added: August 6, 2018

2013 journal article

Growth Requirements and Chromosomal Instability of Induced Pluripotent Stem Cells Generated from Adult Canine Fibroblasts

Stem Cells and Development, 22(6), 951–963.

By: S. Koh n, R. Thomas n, S. Tsai n, S. Bischoff n, J. Lim n, M. Breen n, N. Olby n, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Alkaline Phosphatase / metabolism; Animals; Antigens, Differentiation / genetics; Antigens, Differentiation / metabolism; Cell Differentiation; Cell Shape; Cells, Cultured; Chromosomal Instability; Coculture Techniques; Comparative Genomic Hybridization; Dogs; Fibroblasts / physiology; Gene Expression; In Situ Hybridization, Fluorescence; Induced Pluripotent Stem Cells / enzymology; Induced Pluripotent Stem Cells / pathology; Induced Pluripotent Stem Cells / transplantation; Kruppel-Like Factor 4; Mice; Mice, SCID; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Teratoma / genetics; Teratoma / pathology; Transcription Factors / biosynthesis; Transcription Factors / genetics
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2013 journal article

Su1099 A Translational Porcine Model of Intestinal Stem Cells

Gastroenterology, 144(5), S-398.

By: L. Gonzalez*, A. Blikslager*, J. Piedrahita* & S. Magness

Sources: Crossref, ORCID
Added: February 5, 2020

2012 journal article

GENERATION AND CHARACTERISATION OF INDUCED PLURIPOTENT STEM CELLS (iPSCs) FROM ADULT CANINE FIBROBLASTS

Reproduction, Fertility and Development, 24(1), 285.

By: J. Piedrahita n, S. Koh n & N. Olby n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2012 conference paper

Generation and characterization of induced pluripotent stem cells (iPS) from adult canine fibroblasts

Reproduction in Domestic Animals, 47, 418–419.

By: S. Koh, S. Tsai, S. Bischoff, R. Thomas, J. Lim, M. Breen, N. Olby, J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Isolation and characterization of neural progenitor cells from adult canine brains

American Journal of Veterinary Research, 73(12), 1963–1968.

By: J. Lim n, S. Koh*, N. Olby*, J. Piedrahita* & C. Mariani*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cell Culture Techniques / veterinary; Cell Differentiation; Cell Lineage; Dogs; Female; Hippocampus / cytology; Hippocampus / metabolism; Immunohistochemistry / veterinary; Lateral Ventricles / cytology; Lateral Ventricles / metabolism; Male; Neural Stem Cells / cytology; Neural Stem Cells / physiology; RNA / analysis; Reverse Transcriptase Polymerase Chain Reaction
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2012 journal article

Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells

EPIGENETICS, 7(5), 429–431.

By: J. Chung n, S. Tsai n, A. James*, B. Thames*, S. Shytle* & J. Piedrahita n

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
author keywords: genomic imprinting; PRIM2; pseudogene; placenta; WBC; SNP; sequencing
MeSH headings : Alleles; DNA Primase / genetics; DNA Primase / metabolism; DNA Replication; Databases, Nucleic Acid; Female; Gene Frequency; Genetic Loci; Genome, Human; Genomic Imprinting; Heterozygote; Humans; Leukocytes / cytology; Leukocytes / enzymology; Molecular Sequence Annotation; Placenta / cytology; Placenta / enzymology; Polymorphism, Single Nucleotide; Pregnancy; Pseudogenes; RNA, Messenger / genetics; RNA, Messenger / metabolism; Transcription, Genetic
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Transgenic Stra8-EYFP pigs: a model for developing male germ cell technologies

TRANSGENIC RESEARCH, 21(2), 383–392.

By: J. Sommer n, L. Jackson n, S. Simpson n, E. Collins n, J. Piedrahita n & R. Petters n

co-author countries: United States of America 🇺🇸
author keywords: Pig; Transgenic; Stra8; Spermatogonia; Marker gene
MeSH headings : Adaptor Proteins, Signal Transducing; Animals; Animals, Genetically Modified / genetics; Animals, Genetically Modified / metabolism; Blotting, Western; Cells, Cultured; Cloning, Molecular; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Gene Expression Regulation, Developmental; Genes, Reporter; Germ Cells / cytology; Germ Cells / metabolism; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Immunohistochemistry; Luminescent Proteins / genetics; Luminescent Proteins / metabolism; Male; Mice; Microscopy, Fluorescence / methods; Mitochondria / genetics; Mitochondria / metabolism; Nuclear Transfer Techniques; Plasmids / genetics; Plasmids / metabolism; Promoter Regions, Genetic; Proteins / genetics; Proteins / metabolism; Swine; Testis / cytology; Testis / metabolism; Transfection; Transgenes; Tretinoin / pharmacology
Source: Web Of Science
Added: August 6, 2018

2011 journal article

336 TRANSGENIC Stra8-EYFP PIGS: A MODEL FOR DEVELOPING MALE GERM CELL TECHNOLOGIES

Reproduction, Fertility and Development, 23(1), 264.

By: J. Sommer n, L. Jackson n, S. Simpson n, E. Collins n, J. Piedrahita n & R. Petters n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: August 28, 2020

2011 conference paper

Perspectives on transgenic livestock in agriculture and biomedicine: An update

Reproduction, Fertility and Development, 23(1), 56–63.

By: J. Piedrahita & N. Olby

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Perspectives on transgenic livestock in agriculture and biomedicine: an update

Reproduction, Fertility and Development, 23(1), 56.

By: J. Piedrahita n & N. Olby n

co-author countries: United States of America 🇺🇸
author keywords: animal models; bioreactors; somatic cell nuclear transfer; spinal cord repair; xenotransplantation
MeSH headings : Agriculture / trends; Animals; Animals, Domestic; Animals, Genetically Modified; Biomedical Technology / trends; Nuclear Transfer Techniques / trends; Nuclear Transfer Techniques / veterinary; Pluripotent Stem Cells; Stem Cell Research
Source: Crossref
Added: February 24, 2020

2011 journal article

Production of ELOVL4 transgenic pigs: a large animal model for Stargardt-like macular degeneration

British Journal of Ophthalmology, 95(12), 1749–1754.

By: J. Sommer n, J. Estrada n, E. Collins n, M. Bedell*, C. Alexander n, Z. Yang*, G. Hughes*, B. Mir n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified; Disease Models, Animal; Electroretinography; Eye Proteins / biosynthesis; Eye Proteins / genetics; Gene Deletion; Immunohistochemistry; Macular Degeneration / metabolism; Macular Degeneration / pathology; Macular Degeneration / physiopathology; Membrane Proteins / biosynthesis; Membrane Proteins / genetics; Microscopy, Fluorescence; Mutation; Retina / metabolism; Retina / pathology; Retina / physiopathology; Swine
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2011 review

The Role of Imprinted Genes in Fetal Growth Abnormalities

[Review of ]. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 91(8), 682–692.

By: J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Epigenesis, Genetic; Female; Fetal Development; Fetus / abnormalities; Gene Expression Regulation, Developmental; Genomic Imprinting / genetics; Humans; Pregnancy; Pregnancy Complications / genetics
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways

PLACENTA, 32(2), 175–182.

By: S. Tsai n, N. Hardison n, A. James*, A. Motsinger-Reif n, S. Bischoff n, B. Thames*, J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: Placenta; Preeclampsia; Maternal hypertension; Sialic acid acetylesterase
MeSH headings : Acetylesterase / biosynthesis; Antigens, CD / biosynthesis; Endoglin; Female; Genome-Wide Association Study; Humans; Infant, Newborn; Inhibins / biosynthesis; Male; Pre-Eclampsia / etiology; Pre-Eclampsia / metabolism; Pregnancy; Protein Array Analysis; Receptors, Cell Surface / biosynthesis; Trophoblasts / physiology; Up-Regulation; Vascular Endothelial Growth Factor Receptor-1 / biosynthesis
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Development of a Model of Sacrocaudal Spinal Cord Injury in Cloned Yucatan MiniPigs for Cellular Transplantation Research

CELLULAR REPROGRAMMING, 12(6), 689–697.

By: J. Lim n, J. Piedrahita n, L. Jackson n, T. Ghashghaei n & N. Olby n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Behavior, Animal; Cauda Equina / pathology; Cauda Equina / surgery; Cell Culture Techniques; Cells, Cultured; Cloning, Organism; Green Fluorescent Proteins / metabolism; Humans; Models, Animal; Nerve Regeneration / physiology; Nuclear Transfer Techniques; Recovery of Function / physiology; Sacrum; Spinal Cord / pathology; Spinal Cord / surgery; Spinal Cord Injuries / pathology; Stem Cell Transplantation / methods; Swine; Swine, Miniature / surgery
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Generation and Characterization of Neurospheres from Canine Adipose Tissue-Derived Stromal Cells

CELLULAR REPROGRAMMING, 12(4), 417–425.

By: J. Lim n, L. Boozer n, C. Mariani n, J. Piedrahita n & N. Olby n

co-author countries: United States of America 🇺🇸
MeSH headings : Adipose Tissue / metabolism; Animals; Biomarkers / metabolism; Blotting, Western; Bone and Bones / cytology; Bone and Bones / metabolism; Cell Differentiation; Cell Lineage; Cells, Cultured; Dogs; Flow Cytometry; Neurons / metabolism; Osteogenesis; Phenotype; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells / cytology; Stromal Cells / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Varying phenotypes in swine versus murine transgenic models constitutively expressing the same human Sonic hedgehog transcriptional activator, K5-HGLI2ΔN

Transgenic Research, 19(5), 869–887.

By: A. McCalla-Martin n, X. Chen*, K. Linder n, J. Estrada n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: Basal cell carcinoma; Pig; Somatic cell nuclear transfer; Gli2; Hedgehog
MeSH headings : Animals; Animals, Genetically Modified / genetics; Animals, Suckling; Epidermis / metabolism; Epidermis / pathology; Female; Fibroblasts / metabolism; Genetic Predisposition to Disease; Hair Follicle / metabolism; Humans; Keratins / metabolism; Kruppel-Like Transcription Factors / genetics; Kruppel-Like Transcription Factors / physiology; Male; Mice; Nuclear Proteins / genetics; Nuclear Proteins / physiology; Phenotype; Pyoderma / etiology; Recombinant Fusion Proteins / physiology; Skin Diseases, Infectious / etiology; Skin Diseases, Infectious / pathology; Species Specificity; Sus scrofa; Swine / metabolism; Transgenes; Zinc Finger Protein Gli2
Sources: Web Of Science, Crossref
Added: August 6, 2018

2009 journal article

Characterization of Conserved and Nonconserved Imprinted Genes in Swine

BIOLOGY OF REPRODUCTION, 81(5), 906–920.

By: S. Bischoff n, S. Tsai n, N. Hardison n, A. Motsinger-Reif n, B. Freking*, D. Nonneman*, G. Rohrer*, J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: assisted reproductive technology; comparative genomic imprinting; epigenetics; gene regulation; genomic imprinting; parthenogenesis; placenta; swine parthenote
MeSH headings : Animals; Female; Fetus / anatomy & histology; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genomic Imprinting / genetics; Oligonucleotide Array Sequence Analysis; Organ Size; Parthenogenesis / genetics; Placenta / anatomy & histology; Polymorphism, Single Nucleotide; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Staining and Labeling; Swine / genetics
Source: Web Of Science
Added: August 6, 2018

2009 journal article

EVALUATION OF THE SERRATIA MARCESCENS NUCLEASE (NucA) AS A TRANSGENIC CELL ABLATION SYSTEM IN PORCINE

ANIMAL BIOTECHNOLOGY, 20(4), 177–185.

By: I. Caballero n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: Ablation; DTA; Fibroblasts; NucA; Porcine
MeSH headings : Animals; Cell Separation / methods; Cells, Cultured; Electroporation / methods; Endodeoxyribonucleases / analysis; Endodeoxyribonucleases / genetics; Endodeoxyribonucleases / metabolism; Endoribonucleases / analysis; Endoribonucleases / genetics; Endoribonucleases / metabolism; Fibroblasts / metabolism; Gene Expression; Gene Transfer Techniques; Rabbits; Serratia / enzymology; Swine
Source: Web Of Science
Added: August 6, 2018

2008 journal article

2 DETECTION OF ANTISENSE TO Igf2r (AIR) RNA IN CATTLE

Reproduction, Fertility and Development, 20(1), 81.

By: W. Farmer, P. Farin, S. Bischoff, J. Alexander, J. Piedrahita* & C. Farin*

Source: Crossref
Added: August 28, 2020

2008 journal article

262: Molecular signatures of preeclampsia in human term placentas

American Journal of Obstetrics and Gynecology, 199(6), S84.

By: S. Tsai n, N. Hardison n, S. Bischoff n, B. Thames*, A. Jamessd*, A. Motsinger-Reif n, J. Piedrahita n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2008 journal article

A comparative study on the efficiency of two enucleation methods in pig somatic cell nuclear transfer: Effects of the squeezing and the aspiration methods

ANIMAL BIOTECHNOLOGY, 19(2), 71–79.

By: E. Lee n, J. Estrada* & J. Piedrahita*

co-author countries: Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: enucleation; in vivo viability; pig; somatic cell nuclear transfer
MeSH headings : Animals; Animals, Newborn; Biotechnology / methods; Embryo Transfer / veterinary; Female; Litter Size; Nuclear Transfer Techniques / veterinary; Oocytes; Pregnancy; Swine
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ)

ANIMAL BIOTECHNOLOGY, 19(1), 6–21.

By: G. Zaunbrecher*, B. Mir*, P. Dunne n, M. Breen n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: extra chromosomal; homologous recombination; somatic cells
MeSH headings : Acetyltransferases / genetics; Animals; Cell Physiological Phenomena; Chromosomes / genetics; DNA Primers; DNA Repair; Plasmids; Recombination, Genetic; Swine; Tumor Suppressor Protein p53 / genetics
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Identification of SNPs and INDELS in swine transcribed sequences using short oligonucleotide microarrays

BMC Genomics, 9(1), 252.

By: S. Bischoff n, S. Tsai n, N. Hardison n, A. York n, B. Freking*, D. Nonneman*, G. Rohrer*, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Base Sequence; Computational Biology; DNA / genetics; Female; Fetus / metabolism; Gene Expression Profiling; INDEL Mutation; Linear Models; Male; Oligonucleotide Array Sequence Analysis / methods; Oligonucleotide Array Sequence Analysis / statistics & numerical data; Placenta / metabolism; Polymorphism, Single Nucleotide; Pregnancy; RNA / genetics; Species Specificity; Swine / genetics
Sources: Web Of Science, Crossref
Added: August 6, 2018

2008 article

Successful cloning of the Yucatan minipig using commercial/occidental breeds as oocyte donors and embryo recipients

Estrada, J. L., Collins, B., York, A., Bischoff, S., Sommer, J., Tsai, S., … Piedrahita, J. A. (2008, June). CLONING AND STEM CELLS, Vol. 10, pp. 287–296.

By: J. Estrada n, B. Collins n, A. York n, S. Bischoff n, J. Sommer n, S. Tsai n, R. Petters n, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cell Line; Cloning, Organism / methods; Fibroblasts / cytology; Microsatellite Repeats; Nuclear Transfer Techniques; Oocytes / physiology; Sus scrofa; Swine; Swine, Miniature / embryology
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Swine generated by somatic cell nuclear transfer have increased incidence of intrauterine growth restriction (IUGR)

CLONING AND STEM CELLS, 9(2), 229–236.

By: J. Estrada n, J. Sommer n, B. Collins n, B. Mir n, A. Martin n, A. York n, R. Petters n, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Birth Weight / physiology; Fetal Growth Retardation; Insemination, Artificial; Litter Size / physiology; Nuclear Transfer Techniques; Swine
Source: Web Of Science
Added: August 6, 2018

2006 journal article

263 USE OF PORCINE PARTHENOTES AND GENE EXPRESSION PROFILING USING MICROARRAYS FOR IDENTIFICATION OF IMPRINTED GENES

Reproduction, Fertility and Development, 18(2), 239.

By: J. Piedrahita*, S. Bischoff, J. Estrada, B. Freking, D. Nonneman, A. Martin, B. Mir, G. Rohrer, S. Tsai

Source: Crossref
Added: August 28, 2020

2006 journal article

32 CRYOPRESERVATION OF DONOR CELLS FOR NUCLEAR TRANSFER: EFFECT OF CELL FREEZING METHOD ON THE EFFICIENCY OF SOMATIC CELL NUCLEAR TRANSFER IN PIGS

Reproduction, Fertility and Development, 18(2), 125.

By: J. Estrada, E. Lee & J. Piedrahita*

Source: Crossref
Added: August 28, 2020

2006 article

Annotation of the Affymetrix(1) porcine genome microarray

Tsai, S., Cassady, J. P., Freking, B. A., Nonneman, D. J., Rohrer, G. A., & Piedrahita, J. A. (2006, August). ANIMAL GENETICS, Vol. 37, pp. 423–424.

By: S. Tsai n, J. Cassady n, B. Freking*, D. Nonneman*, G. Rohrer* & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; DNA Probes; Gene Expression Profiling; Genomics; Humans; Oligonucleotide Array Sequence Analysis; Sequence Homology, Nucleic Acid; Swine / genetics
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Dermatological effects of chronic exposure to 7,12-dimethylbenz[a]anthracene (DMBA) or N-methyl-N-nitrosoguanidine (MNNG) in swine

CUTANEOUS AND OCULAR TOXICOLOGY, 25(2), 103–119.

By: N. Monteiro-Riviere n, A. Inman n, V. Hedgpeth n, B. Mosteller n & J. Piedrahita n

co-author countries: United States of America 🇺🇸

Contributors: N. Monteiro-Riviere n, A. Inman n, V. Hedgpeth n, B. Mosteller n & J. Piedrahita n

author keywords: DMBA; MNNG; skin cancer; swine
MeSH headings : 9,10-Dimethyl-1,2-benzanthracene / toxicity; Analysis of Variance; Animals; Cocarcinogenesis; Female; Methylnitronitrosoguanidine / toxicity; Neoplasms, Radiation-Induced; Skin / drug effects; Skin / radiation effects; Skin Neoplasms / chemically induced; Swine; Ultraviolet Rays
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Detection of transcriptional difference of porcine imprinted genes using different microarray platforms

BMC Genomics, 7, 328–336.

By: S. Tsai, B. Mir, A. Martin, J. Estrada, S. Bischoff, W. Hsieh, J. Cassady, B. Freking ...

Source: NC State University Libraries
Added: August 6, 2018

2006 article

Errors in development of fetuses and placentas from in vitro-produced bovine embryos

Farin, P. W., Piedrahita, J. A., & Farin, C. E. (2006, January 7). THERIOGENOLOGY, Vol. 65, pp. 178–191.

By: P. Farin n, J. Piedrahita n & C. Farin n

co-author countries: United States of America 🇺🇸
author keywords: bovine; embryo culture; nuclear transfer; fetus; placenta
MeSH headings : Animals; Breeding / methods; Cattle / embryology; Embryo Culture Techniques / methods; Embryo Culture Techniques / veterinary; Embryo Transfer / veterinary; Embryonic Development; Female; Fertilization in Vitro / veterinary; Gene Expression Regulation, Developmental; Male; Nuclear Transfer Techniques; Phenotype; Placenta / blood supply; Placenta / physiology; Placentation; Pregnancy; Pregnancy Complications / epidemiology; Pregnancy Complications / veterinary; Pregnancy Outcome / veterinary
Source: Web Of Science
Added: August 6, 2018

2005 journal article

51 PHENOTYPIC VARIATION IN CLONED SWINE IS CORRECTED IN THE F1 GENERATION

Reproduction, Fertility and Development, 17(2), 175.

By: B. Mir n, G. Zaunbrecher & J. Piedrahita n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: August 28, 2020

2005 journal article

Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies

TOXICOLOGY AND APPLIED PHARMACOLOGY, 203(1), 18–26.

By: O. Spiegelstein*, A. Gould*, B. Wlodarczyk*, M. Tsie*, X. Lu*, C. Le*, A. Troen*, J. Selhub* ...

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
author keywords: arsenic; teratogenicity; biotransformation; detoxification; Folbp1; RFC; neural tube defects
MeSH headings : Animals; Arsenates / toxicity; Biological Transport; Carrier Proteins / genetics; Carrier Proteins / metabolism; Chimera; Female; Folate Receptors, GPI-Anchored; Folic Acid / blood; Folic Acid / metabolism; Folic Acid Deficiency / embryology; Genotype; Male; Membrane Transport Proteins / deficiency; Membrane Transport Proteins / genetics; Membrane Transport Proteins / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; No-Observed-Adverse-Effect Level; Receptors, Cell Surface / deficiency; Receptors, Cell Surface / genetics; Receptors, Cell Surface / metabolism; Reduced Folate Carrier Protein; Reproduction / drug effects
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis

Cancer Research, 65(3), 887–897.

By: D. Ma, R. Finnell, L. Davidson, E. Callaway, O. Spiegelstein, J. Piedrahita, J. Salbaum, C. Kappen ...

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Progeny of somatic cell nuclear transfer (SCNT) pig clones are phenotypically similar to non-cloned pigs

CLONING AND STEM CELLS, 7(2), 119–125.

By: B. Mir n, G. Zaunbrecher*, G. Archer*, T. Friend* & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Body Weight; Cloning, Organism; Female; Litter Size; Male; Nuclear Transfer Techniques; Phenotype; Sex Ratio; Swine / genetics
Source: Web Of Science
Added: August 6, 2018

2004 journal article

343NUCLEAR LOCALIZATION SIGNAL AND CELL SYNCHRONY ENHANCES GENE TARGETING EFFICIENCY IN FETAL BOVINE FIBROBLASTS

Reproduction, Fertility and Development, 16(2), 291.

By: B. Mir & J. Piedrahita*

Source: Crossref
Added: August 28, 2020

2004 journal article

35 Analysis of epigenetic modifications and genomic imprinting in nuclear transfer derived Bos Gaurus x B. Taurus Concepti

Reproduction, Fertility and Development, 16(2), 140.

By: S. Dindot*, P. Farin, C. Farin*, J. Alexander, E. Crosier, S. Walker*, C. Long*, J. Piedrahita*

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: December 29, 2020

2004 journal article

67ORGAN WEIGHT VARIATION IN CLONED PIGS

Reproduction, Fertility and Development, 16(2), 155.

By: J. Piedrahita*, S. Walker* & G. Zaunbrecher*

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: August 28, 2020

2004 journal article

Cloning and transgenesis in mammals: Implications for xenotransplantation

AMERICAN JOURNAL OF TRANSPLANTATION, 4, 43–50.

By: J. Piedrahita n & B. Mir n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified; Cloning, Organism; Embryo, Mammalian / cytology; Graft Rejection / etiology; Graft Rejection / immunology; Graft Rejection / prevention & control; Humans; Immune Tolerance; Immunosuppression Therapy; Nuclear Transfer Techniques; Stem Cells / cytology; Swine; Transplantation, Heterologous / immunology; Transplantation, Heterologous / methods; Transplantation, Heterologous / trends
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Comparative PRNP genotyping of US cattle sires for potential association with BSE

MAMMALIAN GENOME, 15(10), 828–833.

By: C. Seabury*, J. Womack*, J. Piedrahita n & J. Derr*

co-author countries: United States of America 🇺🇸
MeSH headings : Alleles; Amyloid / genetics; Animals; Cattle / genetics; Encephalopathy, Bovine Spongiform / genetics; Genetic Variation; Genotype; Germany; Polymorphism, Single Nucleotide; Prions; Promoter Regions, Genetic / genetics; Protein Precursors / genetics; United States
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Conservation of genomic imprinting at the XIST, IGF2, and GTL2 loci in the bovine

Mammalian Genome, 15(12), 966–974.

By: S. Dindot*, K. Kent*, B. Evers*, N. Loskutoff, J. Womack* & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Alleles; Animals; Base Sequence; Cattle; DNA Methylation; Female; Gene Expression Regulation; Genomic Imprinting / genetics; Humans; Insulin-Like Growth Factor II / genetics; Male; Molecular Sequence Data; Placenta; Polymorphism, Single Nucleotide; Proteins / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics; Sequence Homology, Nucleic Acid; Sheep
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Development of fetuses from in vitro produced and cloned bovine embryos

Journal of Animal Science, 82(Supplement 13), E53–E62.

By: C. Farin n, P. Farin n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cattle / embryology; Cattle / genetics; Cattle / growth & development; Cloning, Organism / adverse effects; Cloning, Organism / veterinary; Embryo Culture Techniques / veterinary; Embryo Transfer / adverse effects; Embryo Transfer / veterinary; Embryonic Development / genetics; Embryonic Development / physiology; Female; Fertilization in Vitro / adverse effects; Fertilization in Vitro / veterinary; Fetal Development / genetics; Fetal Development / physiology; Gene Expression Regulation, Developmental / physiology; Male; Pregnancy
Source: NC State University Libraries
Added: October 29, 2021

2004 journal article

Epigenetic and genomic imprinting analysis in nuclear transfer derived Bos gaurus/Bos taurus hybrid fetuses

Biology of Reproduction, 71(2), 470–478.

By: S. Dindot n, P. Farin n, C. Farin n, J. Romano*, S. Walker*, C. Long, J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cattle; Chimera / genetics; Cloning, Organism; DNA Methylation; DNA, Satellite; Embryonic Development; Epidermis / physiology; Epigenesis, Genetic / genetics; Exons; Female; Fibroblasts / physiology; Genomic Imprinting / genetics; Genotype; Insulin-Like Growth Factor II / genetics; Keratins / genetics; Nuclear Transfer Techniques; Placenta; Pregnancy; Promoter Regions, Genetic; Proteins / genetics; RNA, Long Noncoding; RNA, Untranslated / genetics
Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Nuclear localization signal and cell synchrony enhance gene targeting efficiency in primary fetal fibroblasts

Nucleic Acids Research, 32(3), e25–e28.

By: B. Mir n & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Azaguanine / pharmacology; Base Sequence; Cattle; Cell Division / drug effects; Cell Division / physiology; Cells, Cultured; Drug Resistance; Fetus; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Gene Targeting / methods; Genetic Vectors / genetics; Hypoxanthine Phosphoribosyltransferase / genetics; Male; Molecular Sequence Data; Mutagenesis, Insertional; Nuclear Localization Signals / genetics
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Somatic cell cloning: The ultimate form of nuclear reprogramming?

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 15(5), 1140–1144.

By: J. Piedrahita*, B. Mir*, S. Dindot* & S. Walker*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cloning, Molecular / methods; Humans; Kidney Failure, Chronic / therapy; Stem Cell Transplantation / methods; Stem Cells / physiology
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Use of artificial androgen receptor coactivators to alter myoblast proliferation

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 91(3), 111–119.

By: C. Benjamin*, G. Jenster* & J. Piedrahita n

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
author keywords: androgen receptor; muscle growth; coactivators
MeSH headings : Animals; Base Sequence; Cell Division / drug effects; DNA Primers; HeLa Cells; Humans; Muscle, Skeletal / cytology; Muscle, Skeletal / drug effects; Mutagenesis, Site-Directed; Rats; Receptors, Androgen / drug effects; Receptors, Androgen / metabolism
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Behavioral variation among cloned pigs

Applied Animal Behaviour Science, 81(4), 321–331.

By: G. Archer*, T. Friend*, J. Piedrahita*, C. Nevill* & S. Walker*

co-author countries: United States of America 🇺🇸
author keywords: pig; swine; clone; behavior; variation; differences
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Behavioral variation among cloned pigs

Applied Animal Behaviour Science, 82(2), 151–161.

By: G. Archer*, T. Friend*, J. Piedrahita*, C. Nevill* & S. Walker*

co-author countries: United States of America 🇺🇸
Source: NC State University Libraries
Added: October 29, 2021

2003 journal article

Hierarchical phenotypic and epigenetic variation in cloned swine

BIOLOGY OF REPRODUCTION, 69(2), 430–436.

By: G. Archer*, S. Dindot*, T. Friend*, S. Walker*, G. Zaunbrecher*, B. Lawhorn*, J. Piedrahita*

co-author countries: United States of America 🇺🇸
author keywords: assisted reproductive technology; developmental biology; embryo; gene regulation
MeSH headings : Animals; Base Sequence; Centromere / genetics; Centromere / ultrastructure; Cloning, Molecular; Cloning, Organism / methods; CpG Islands / genetics; DNA Methylation; DNA, Satellite / genetics; Female; Genotype; Methylation; Mitochondria / metabolism; Molecular Sequence Data; Phenotype; Reference Values; Repetitive Sequences, Nucleic Acid; Reverse Transcriptase Polymerase Chain Reaction; Sulfites / pharmacology; Swine / genetics
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Kidney-specific activity of the bovine uromodulin promoter

TRANSGENIC RESEARCH, 12(2), 191–201.

By: H. Kim*, I. Song* & J. Piedrahita*

co-author countries: Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: bovine uromodulin promoter; kidney expression; transgenic mice
MeSH headings : Animals; Base Sequence; Cattle; Cloning, Molecular; DNA Primers; In Situ Hybridization; Kidney Tubules / metabolism; Mice; Mice, Transgenic; Mucoproteins / genetics; NIH 3T3 Cells; Promoter Regions, Genetic; Uromodulin
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Mutational analysis of LoxP sites for efficient Cre-mediated insertion into genomic DNA

GENESIS, 36(3), 162–167.

By: J. Thomson*, E. Rucker* & J. Piedrahita n

co-author countries: United States of America 🇺🇸
author keywords: Cre recombinase; mutant loxP; insertion; lambda integrase
MeSH headings : Base Sequence; DNA Mutational Analysis; DNA Primers; Electroporation; Integrases / genetics; Molecular Sequence Data; Mutagenesis, Insertional / methods; Mutation / genetics; Plasmids / genetics; Viral Proteins / genetics
Source: Web Of Science
Added: August 6, 2018

2003 journal article

UP1 extends life of primary porcine fetal fibroblasts in culture

CLONING AND STEM CELLS, 5(2), 143–148.

By: B. Mir n, N. Tanner*, B. Chowdhary* & J. Piedrahita n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Antioxidants / pharmacology; Cell Survival / drug effects; Cells, Cultured; Chromosome Aberrations; Culture; Electroporation; Fetus / cytology; Fibroblasts / cytology; Fibroblasts / drug effects; Glutathione / pharmacology; Heterogeneous-Nuclear Ribonucleoprotein Group A-B / genetics; Heterogeneous-Nuclear Ribonucleoprotein Group A-B / metabolism; Hydroxylamines / pharmacology; Karyotyping; Swine / embryology
Source: Web Of Science
Added: August 6, 2018

2002 journal article

A highly efficient method for porcine cloning by nuclear transfer using in vitro-matured oocytes

Cloning and Stem Cells, 2, 105–112.

By: S. Walker*, T. Shin*, G. Zaunbrecher*, J. Romano*, G. Johnson*, F. Bazer*, J. Piedrahita*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cloning, Organism / methods; Culture Techniques; Embryo Transfer; Female; Microsatellite Repeats / genetics; Nuclear Transfer Techniques; Oocytes / cytology; Pregnancy; Sex Ratio; Swine / genetics
Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Effects of follicular size of cytoplast donor on the efficiency of cloning in cattle

MOLECULAR REPRODUCTION AND DEVELOPMENT, 61(3), 317–326.

By: J. Piedrahita*, D. Wells*, A. Miller*, J. Oliver*, M. Berg*, A. Peterson*, H. Tervit*

co-author countries: New Zealand 🇳🇿 United States of America 🇺🇸
author keywords: embryo development; nuclear transfer; oocyte quality
MeSH headings : Animals; Blastocyst / cytology; Body Weight; Cattle; Cell Nucleus / physiology; Cloning, Organism / methods; Culture Techniques; Cytoplasm / physiology; Cytoplasm / transplantation; Embryo Transfer; Embryo, Mammalian / cytology; Embryo, Mammalian / embryology; Embryonic and Fetal Development; Female; Fertilization in Vitro; Microsatellite Repeats / genetics; Nuclear Transfer Techniques; Oocytes / cytology; Oocytes / growth & development; Oocytes / transplantation; Ovarian Follicle / anatomy & histology; Ovarian Follicle / cytology; Ovarian Follicle / transplantation; Pregnancy; Ultrasonography, Prenatal
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Inhibition of apoptosis in serum starved porcine embryonic fibroblasts

MOLECULAR REPRODUCTION AND DEVELOPMENT, 62(1), 106–112.

By: C. Lee* & J. Piedrahita*

co-author countries: United States of America 🇺🇸
author keywords: cell synchronization; antioxidants; G(0)/G(1)
MeSH headings : Acetylcysteine / pharmacology; Animals; Antioxidants / pharmacology; Apoptosis; Cells, Cultured; Culture Media, Serum-Free; Female; Fibroblasts / cytology; Fibroblasts / drug effects; Free Radical Scavengers / pharmacology; Protease Inhibitors / pharmacology; Swine; alpha-Macroglobulins / pharmacology
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Inactivation of the whey acidic protein (WAP) gene by site-specific recombination in mouse embryonic stem cells

Journal of Animal Science, 42(6), 941–956.

By: C. Lee & J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Stable transfection of the bovine NRAMP1 gene into murine RAW264.7 cells: effect on Brucella abortus survival

Infection and Immunity, 69(5), 3110–3119.

By: R. Barthel, J. Feng*, J. Piedrahita*, D. McMurray*, J. Templeton & L. Adams

co-author countries: United States of America 🇺🇸
MeSH headings : 3' Untranslated Regions; Animals; Base Sequence; Brucella abortus / growth & development; Carrier Proteins / genetics; Carrier Proteins / physiology; Cation Transport Proteins; Cattle; Cell Line; Interferon-gamma / pharmacology; Lipopolysaccharides / pharmacology; Macrophages / microbiology; Male; Membrane Proteins / genetics; Membrane Proteins / physiology; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nitric Oxide / physiology; Transfection; Tumor Necrosis Factor-alpha / physiology
Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

A rapid and sensitive reporter gene that uses green fluorescent protein expression to detect chemicals with estrogenic activity

TOXICOLOGICAL SCIENCES, 55(1), 69–77.

By: S. Miller*, D. Kennedy, J. Thomson, F. Han, R. Smith, N. Ing, J. Piedrahita*, D. Busbee

co-author countries: United States of America 🇺🇸
author keywords: cellular steroid receptors; endocrine disruption; xenobiotics; transfection; MCF7-ERE cells; estrogenic activity
MeSH headings : Cell Division / drug effects; Cell Line; Drug Evaluation, Preclinical; Estradiol / pharmacology; Estradiol Congeners / pharmacology; Eukaryotic Cells / drug effects; Genes, Reporter / drug effects; Genes, Reporter / genetics; Green Fluorescent Proteins; Humans; Luminescent Proteins / biosynthesis; Luminescent Proteins / genetics; Phosphoglycerate Kinase / metabolism; Plasmids / genetics; Receptors, Estrogen / drug effects; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Serum Albumin, Bovine / chemistry; Tamoxifen / analogs & derivatives; Tamoxifen / pharmacology; Transfection
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Effects of growth factors and feeder cells on porcine primordial germ cells in vitro

Cloning and Stem Cells, 2, 197–206.

By: C. Lee* & J. Piedrahita*

co-author countries: United States of America 🇺🇸
MeSH headings : Alkaline Phosphatase / metabolism; Animals; Animals, Genetically Modified; COS Cells; Cell Culture Techniques; Cell Differentiation; Cell Membrane / metabolism; Chlorocebus aethiops; Culture Media / pharmacology; Embryo Culture Techniques; Embryo, Mammalian / cytology; Fibroblast Growth Factor 2 / metabolism; Fibroblasts / metabolism; Germ Cells / cytology; Germ Cells / metabolism; Growth Substances; Interleukin-6 / metabolism; Leukemia Inhibitory Factor; Lewis X Antigen / metabolism; Stem Cell Factor / metabolism; Stem Cells / cytology; Swine
Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Effects of protease inhibitors and antioxidants on in vitro survival of porcine primordial germ cells

BIOLOGY OF REPRODUCTION, 63(3), 887–897.

By: C. Lee*, R. Weaks*, G. Johnson*, F. Bazer* & J. Piedrahita*

co-author countries: United States of America 🇺🇸
author keywords: apoptosis; conceptus; cytokines; growth factors
MeSH headings : Acetylcysteine / administration & dosage; Acetylcysteine / pharmacology; Animals; Antioxidants / pharmacology; Apoptosis / drug effects; Cell Survival / drug effects; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Fetus / cytology; Germ Cells / drug effects; Germ Cells / physiology; In Situ Nick-End Labeling; Microscopy, Electron; Protease Inhibitors / pharmacology; Swine; alpha-Macroglobulins / administration & dosage; alpha-Macroglobulins / pharmacology
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Gene targeting in domestic species: A new beginning

Transgenic Res, 9(4/5), 261–262.

By: J. Piedrahita*

MeSH headings : Animals; Animals, Domestic / genetics; Gene Targeting / methods; Gene Targeting / veterinary
Source: Web Of Science
Added: October 29, 2021

2000 journal article

Isolation and genetic transformation of primordial germ cell (PGC)-derived cells from cattle, goats, rabbits and rats

ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 13(5), 587–594.

By: C. Lee, K. Moore, N. Scales, M. Westhusin, G. Newton, K. Im, J. Piedrahita*

author keywords: primordial germ cell; embryonic germ cell; alkaline phosphatase staining; embryoid body; genetic transformation; green fluorescent protein
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Pathologic findings and association of Mycobacterium bovis infection with the bovine NRAMP1 gene in cattle from herds with naturally occurring tuberculosis

AMERICAN JOURNAL OF VETERINARY RESEARCH, 61(9), 1140–1144.

By: R. Barthel, J. Piedrahita*, D. McMurray, J. Payeur, D. Baca, F. Guemes, V. Perumaalla, T. Ficht, J. Templeton, L. Adams

MeSH headings : Alleles; Animals; Carrier Proteins / genetics; Cation Transport Proteins; Cattle / genetics; Genetic Predisposition to Disease / genetics; Genotype; Immunity, Innate / genetics; Membrane Proteins / genetics; Mycobacterium bovis / isolation & purification; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Tuberculosis, Bovine / genetics; Tuberculosis, Bovine / pathology
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Three little pigs worth the huff and puff?

Nature Biotechnology, 18(11), 1144–1145.

By: M. Westhusin & J. Piedrahita*

MeSH headings : Animals; Cell Nucleus / metabolism; Cloning, Organism; Culture Techniques / methods; Ovum / metabolism; Swine; Transplantation, Heterologous
Source: Crossref
Added: July 27, 2019

1999 journal article

Inactivation of the folate binding protein genes disrupts neural tube closure.

Nature Genetics, 23, 228–232.

By: J. Piedrahita, B. Oetama, G. Bennett, J. Waes, S. Lacey, B. Kamen, J. Richardson, R. Lark, R. Finnell

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Regulated Expression of MHC class I molecules in the porcine embryo

Biology of Reproduction, 60, 387–397.

By: J. Ramsoondar, R. Christopherson, L. Guilbert, W. Dixon, A. Ghahary, S. Ellis, T. Wegmann, J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Cellular differentiation and I-FABP protein expression modulate fatty acid uptake and diffusion

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 274(3), C633–C644.

By: B. Atshaves, W. Foxworth, A. Frolov, J. Roths, A. Kier, B. Oetama, J. Piedrahita*, F. Schroeder

author keywords: embryonic stem cells; intracellular localization; laser cytometry; fluorescence recovery after photobleaching; intestinal fatty acid binding protein
MeSH headings : 4-Chloro-7-nitrobenzofurazan / analogs & derivatives; 4-Chloro-7-nitrobenzofurazan / pharmacokinetics; Animals; Carrier Proteins / biosynthesis; Carrier Proteins / genetics; Cell Differentiation; Cells, Cultured; Clone Cells / metabolism; Diffusion; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids / metabolism; Indicators and Reagents / pharmacokinetics; Mice; Myelin P2 Protein / biosynthesis; Myelin P2 Protein / genetics; Neoplasm Proteins; Nerve Tissue Proteins; Polymerase Chain Reaction; Restriction Mapping; Stearates / pharmacokinetics; Stem Cells / metabolism; Transfection
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Factors affecting the efficiency of introducing precise genetic changes in ES cells by homologous recombination: tag-and-exchange versus the Cre-loxp system

TRANSGENIC RESEARCH, 7(3), 181–193.

By: J. Vazquez*, C. Nogues*, E. Rucker* & J. Piedrahita*

co-author countries: Mexico 🇲🇽 United States of America 🇺🇸
author keywords: gene targeting; homologous recombination; Cre-LoxP; site-specific recombination
MeSH headings : Animals; Apolipoproteins E / genetics; Cells, Cultured; Electroporation; Embryo, Mammalian / cytology; Gene Targeting; Genetic Markers; Genetic Vectors; Integrases / metabolism; Mice; Milk Proteins / genetics; Mutation; Plasmids; Recombination, Genetic; Selection, Genetic; Stem Cells; Thymidine Kinase / genetics; Viral Proteins
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Generation of transgenic porcine chimeras using primordial germ cell-derived colonies

BIOLOGY OF REPRODUCTION, 58(5), 1321–1329.

By: J. Piedrahita*, K. Moore*, B. Oetama*, C. Lee*, N. Scales*, J. Ramsoondar*, F. Bazer*, T. Ott*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Animals, Genetically Modified / genetics; Animals, Genetically Modified / physiology; Blotting, Southern; Cell Differentiation / physiology; Cells, Cultured; Chimera / genetics; Female; Germ Cells / physiology; Pregnancy; Swine; Transformation, Genetic
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Isolation, characterization, and polymorphism detection of the porcine apolipoprotein E gene

Animal Genetics, 29, 43–47.

By: J. Ramsoondar*, J. Vazques, E. Rucker*, R. Dickson, J. Lunney & J. Piedrahita*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Apolipoproteins E / chemistry; Apolipoproteins E / genetics; Apolipoproteins E / isolation & purification; Base Sequence; Chromosome Mapping / veterinary; Cloning, Molecular; DNA Primers; Disease Models, Animal; Exons / genetics; Gene Frequency; In Situ Hybridization, Fluorescence / veterinary; Introns / genetics; Microsatellite Repeats / genetics; Molecular Sequence Data; Protein Sorting Signals / genetics; Restriction Mapping / veterinary; Sequence Analysis, DNA / veterinary; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Swine / genetics
Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Cre-mediated site-directed insertions at the mouse whey acidic protein (mWAP) locus

Molecular Reproduction and Development, 48, 324–331.

By: E. Rucker* & J. Piedrahita*

co-author countries: United States of America 🇺🇸
Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Effect of LIF and culture media on the in vitro differentiation of isolated porcine inner cell masses

In Vitro Cellular & Developmental Biology. Animal, 33, 61–70.

By: K. Moore & J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Genetic characterization of the bovine leukaemia inhibitory factor (LIF) gene: Isolation and sequencing, chromosome assignment and microsatellite analysis

ANIMAL GENETICS, 28(1), 14–20.

By: J. Piedrahita*, R. Weaks*, A. Petrescu*, T. Shrode*, J. Derr* & J. Womack*

co-author countries: United States of America 🇺🇸
author keywords: bovine; chromosome 17; leukaemia inhibitory factor; LIF; mapping; microsatellite
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cattle; Chromosome Mapping; Cloning, Molecular; Genes / genetics; Growth Inhibitors / genetics; Interleukin-6; Introns / genetics; Leukemia Inhibitory Factor; Lymphokines / genetics; Microsatellite Repeats / genetics; Molecular Sequence Data; Polymorphism, Restriction Fragment Length; Regulatory Sequences, Nucleic Acid / genetics; Sequence Analysis, DNA; Sequence Homology, Amino Acid
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Isolation, characterization, and chromosome assignment of the porcine ciliary neurotrophic factor

Animal Genetics, 28, 354–357.

By: R. Weaks, J. Ramsoondar, D. Gallager, C. Nogues & J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Progress on the generation of transgenic pigs via cultured cells

Journal of Reproduction & Fertility, 52, 245–254.

By: J. Piedrahita, K. Moore, C. Lee, R. Weaks, J. Ramsoondar, B. Oetama, J. Vasquez

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Strain dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model.

American Journal of Medical Genetics. Part A, 70, 303–311.

By: R. Finnell*, B. Wlodarczyk*, J. Craig*, J. Piedrahita* & G. Bennett*

co-author countries: United States of America 🇺🇸
Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Effect of hematopoetic cytokines on in vitro differentiation of isolated porcine inner cell masses

Molecular Reproduction and Development, 45, 139–144.

By: K. Moore & J. Piedrahita

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

CHARACTERISTICS OF CLONED CEREBROVASCULAR ENDOTHELIAL-CELLS FOLLOWING INFECTION WITH THEILERS VIRUS .2. PERSISTENT INFECTION

JOURNAL OF NEUROIMMUNOLOGY, 62(2), 127–135.

By: B. Sapatino*, A. Petrescu*, B. Rosenbaum*, R. Smith*, J. Piedrahita* & C. Welsh

co-author countries: United States of America 🇺🇸
author keywords: CEREBROVASCULAR ENDOTHELIAL CELLS; THEILERS VIRUS; PERSISTENT INFECTION; MHC CLASS I; FLOW CYTOMETRY
MeSH headings : Animals; Antigens, Viral / analysis; Brain / blood supply; Brain / virology; Clone Cells; Endothelium, Vascular / immunology; Endothelium, Vascular / virology; Flow Cytometry; Histocompatibility Antigens Class I / analysis; Histocompatibility Antigens Class II / analysis; Interleukin-1 / genetics; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Poliomyelitis / immunology; Poliomyelitis / virology; Theilovirus / immunology; Theilovirus / isolation & purification
Source: Web Of Science
Added: August 6, 2018

1992 journal article

GENERATION OF MICE CARRYING A MUTANT APOLIPOPROTEIN-E GENE INACTIVATED BY GENE TARGETING IN EMBRYONIC STEM-CELLS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 89(10), 4471–4475.

By: J. Piedrahita*, S. Zhang*, . Hagaman*, P. Oliver* & N. Maeda*

co-author countries: United States of America 🇺🇸
author keywords: HOMOLOGOUS RECOMBINATION; ATHEROSCLEROSIS
MeSH headings : Animals; Apolipoproteins E / genetics; Base Sequence; Blotting, Southern; Cell Line; Chimera; DNA / genetics; DNA / isolation & purification; Embryo, Mammalian; Mice; Mice, Mutant Strains; Molecular Sequence Data; Oligodeoxyribonucleotides; Plasmids; Polymerase Chain Reaction / methods; Recombination, Genetic; Restriction Mapping; Stem Cells / physiology
Source: Web Of Science
Added: August 6, 2018

1992 journal article

PRODUCTION OF CHIMERIC HAMSTERS BY AGGREGATION OF 8-CELL EMBRYOS

BIOLOGY OF REPRODUCTION, 47(3), 347–354.

By: J. Piedrahita*, L. Gillespie* & N. Maeda*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Blastocyst / cytology; Cell Aggregation; Chimera; Cricetinae; Female; Hair Color / genetics; Infertility, Male / genetics; Infertility, Male / pathology; Male; Mesocricetus; Phenotype; Reproduction; Spermatozoa / pathology; Testis / pathology
Source: Web Of Science
Added: August 6, 2018

1992 journal article

SPONTANEOUS HYPERCHOLESTEROLEMIA AND ARTERIAL LESIONS IN MICE LACKING APOLIPOPROTEIN-E

SCIENCE, 258(5081), 468–471.

By: S. Zhang*, R. Reddick*, J. Piedrahita* & N. Maeda*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Apolipoproteins E / deficiency; Apolipoproteins E / genetics; Cholesterol / blood; Disease Models, Animal; Hypercholesterolemia / genetics; Hypercholesterolemia / pathology; Lipoproteins / metabolism; Mice; Mice, Mutant Strains; Mutagenesis, Insertional; Triglycerides / blood
Source: Web Of Science
Added: August 6, 2018

1990 journal article

INFLUENCE OF FEEDER LAYER TYPE ON THE EFFICIENCY OF ISOLATION OF PORCINE EMBRYO-DERIVED CELL-LINES

THERIOGENOLOGY, 34(5), 865–877.

By: J. Piedrahita*, G. Anderson* & R. Bondurant*

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

1990 journal article

ON THE ISOLATION OF EMBRYONIC STEM-CELLS - COMPARATIVE BEHAVIOR OF MURINE, PORCINE AND OVINE EMBRYOS

THERIOGENOLOGY, 34(5), 879–901.

By: J. Piedrahita*, G. Anderson* & R. Bondurant*

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: August 6, 2018

1989 journal article

PRODUCTION AND CHARACTERIZATION OF MONOCLONAL-ANTIBODIES AGAINST THE H-Y-ANTIGEN

JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 15(3), 195–205.

By: P. Booman, L. Kruijt, M. Tieman, J. Piedrahita*, R. Veerhuis, P. Deboer, F. Ruch*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Antibodies, Monoclonal / biosynthesis; Antibodies, Monoclonal / immunology; Cattle; Cells, Cultured; Female; H-Y Antigen / immunology; Hybridomas / immunology; Male; Mice; Rabbits; Sex Characteristics; Testis / immunology
Source: Web Of Science
Added: August 6, 2018

1985 journal article

Investigation of sperm cytotoxicity as an indicator of ability of antisera to detect male-specific antigen on preimplantation mouse embryos

Journal of Reproduction & Fertility, 74, 637–644.

By: J. Piedrahita* & G. Anderson

MeSH headings : Adenosine Triphosphate / analysis; Animals; Blastocyst / immunology; Cytotoxicity, Immunologic; Embryo Transfer; Fluorescent Antibody Technique; H-Y Antigen / analysis; H-Y Antigen / immunology; Immune Sera / immunology; Male; Mice; Mice, Inbred C57BL; Spermatozoa / immunology; Spleen / immunology
Source: NC State University Libraries
Added: August 6, 2018

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