Julien Bruno Curaba

Works (6)

Updated: April 25th, 2025 19:09

2024 article

Functional recovery following traumatic brain injury in rats is enhanced by oral supplementation with bovine thymus extract

Surzenko, N., Bastidas, J., Reid, R. W., Curaba, J., Zhang, W., Bostan, H., … El‐Khodor, B. F. (2024, February 5). The FASEB Journal, Vol. 38.

By: N. Surzenko *, J. Bastidas*, R. Reid *, J. Curaba* , W. Zhang*, H. Bostan*, M. Wilson*, A. Dominique* ...

author keywords: autoantibodies; autophagy; glandular therapy; nutrition; oral tolerance; phagocytosis; RNA-Seq
MeSH headings : Humans; Rats; Animals; Cattle; Thymus Extracts / pharmacology; Thymus Extracts / therapeutic use; Brain Injuries, Traumatic / drug therapy; Neurons; Neuroglia; Hippocampus; Disease Models, Animal
topics (OpenAlex): Traumatic Brain Injury and Neurovascular Disturbances; Vitamin C and Antioxidants Research; Mitochondrial Function and Pathology
TL;DR: The potency of a nutritional supplement containing nuclear fraction of bovine thymus in enhancing the functional recovery from TBI is demonstrated, for the first time, in enhancing the functional recovery from TBI. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 19, 2024

2023 article

Functional characterization of DcMYB11, an R2R3 MYB associated with the purple pigmentation of carrot petiole

Vincenzo, D. A., Curaba, J., Abid, M. A., Esposito, S., Cavagnaro, P., Carputo, D., & Iorizzo, M. (2023, July 24). Planta, Vol. 258.

By: D. Vincenzo *, J. Curaba n , M. Abid n, S. Esposito *, P. Cavagnaro *, D. Carputo *, M. Iorizzo n 

author keywords: Anthocyanins; Carrot petiole; Daucus carota; Regulatory sequences; Transcription factor
MeSH headings : Daucus carota; Anthocyanins; Pigmentation; Alleles; Crops, Agricultural
topics (OpenAlex): Plant Gene Expression Analysis; Plant biochemistry and biosynthesis; Phytochemicals and Antioxidant Activities
TL;DR: This study provides novel insight into the molecular mechanisms controlling anthocyanin accumulation in carrot and expanded the knowledge on the cis-regulatory sequences in plants by identifying three different alleles which may explain differences in petiole pigmentation. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 14, 2023

2023 article

Population genomics identifies genetic signatures of carrot domestication and improvement and uncovers the origin of high-carotenoid orange carrots

Coe, K., Bostan, H., Rolling, W., Turner-Hissong, S., Macko-Podgórni, A., Senalik, D., … Iorizzo, M. (2023, September 28). Nature Plants, Vol. 9.

By: K. Coe  n, H. Bostan n, W. Rolling *, S. Turner-Hissong *, A. Macko-Podgórni *, D. Senalik *, S. Liu  n, R. Seth n  ...

MeSH headings : beta Carotene / metabolism; Daucus carota / genetics; Daucus carota / metabolism; Domestication; Metagenomics; Plant Breeding; Carotenoids / metabolism
topics (OpenAlex): Antioxidant Activity and Oxidative Stress; Cholesterol and Lipid Metabolism; Plant biochemistry and biosynthesis
TL;DR: It is demonstrated that carrot was domesticated during the Early Middle Ages in the region spanning western Asia to central Asia, and orange carrot was selected during the Renaissance period, probably in western Europe, through the selection of three recessive genes that increased the provitamin A carotenoid (α- and β-carotene) content. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 16, 2023

2021 article

Improved High-Quality Genome Assembly and Annotation of Pineapple (Ananas comosus) Cultivar MD2 Revealed Extensive Haplotype Diversity and Diversified FRS/FRF Gene Family

Yow, A. G., Bostan, H., Castanera, R., Ruggieri, V., Mengist, M. F., Curaba, J., … Iorizzo, M. (2021, December 24). Genes, Vol. 13.

By: A. Yow n , H. Bostan n, R. Castanera *, V. Ruggieri, M. Mengist n, J. Curaba n , R. Young*, N. Gillitt*, M. Iorizzo n 

author keywords: pineapple MD2; Ananas comosus; improved assembly; haplotype diversity; FHY3; FAR1 genes; FRS; FRF genes
MeSH headings : Ananas / genetics; Ananas / growth & development; Chromosome Mapping; Chromosomes, Plant / genetics; Gene Expression Regulation, Plant; Genetic Variation; Genome, Plant; Genomics; Haplotypes; Molecular Sequence Annotation / methods; Plant Proteins / genetics; Sequence Analysis, DNA
topics (OpenAlex): Pineapple and bromelain studies; Banana Cultivation and Research; Plant tissue culture and regeneration
TL;DR: The new MD2 assembly will serve as a new reference for genetic and genomic studies in pineapple, and over 48% of the predicted genes harbored potential deleterious mutations, indicating that the high level of heterozygosity in this species contributes to maintaining functional alleles. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 27, 2021

2020 article

Carrot Anthocyanins Genetics and Genomics: Status and Perspectives to Improve Its Application for the Food Colorant Industry

Iorizzo, M., Curaba, J., Pottorff, M., Ferruzzi, M. G., Simon, P., & Cavagnaro, P. F. (2020, August 7). Genes, Vol. 11, p. 906.

By: M. Iorizzo n , J. Curaba n , M. Pottorff n, M. Ferruzzi n, P. Simon * & P. Cavagnaro*

author keywords: anthocyanins; carrots; natural colorant; genetics
MeSH headings : Anthocyanins / chemistry; Anthocyanins / metabolism; Biological Products / chemistry; Biological Products / metabolism; Chemical Phenomena; Daucus carota / classification; Daucus carota / genetics; Daucus carota / metabolism; Food Coloring Agents / chemistry; Food Coloring Agents / metabolism; Food Industry; Gene Expression Regulation, Plant; Genetic Association Studies; Genome, Plant; Genomics / methods; Pigmentation / genetics; Plant Proteins / genetics; Quantitative Trait, Heritable
topics (OpenAlex): Plant Gene Expression Analysis; Phytochemicals and Antioxidant Activities; Plant biochemistry and biosynthesis
TL;DR: A view of the current knowledge gaps and advancement needs as regards developing and applying innovative molecular tools to improve the yield, product performance and stability of carrot anthocyanin for use as a natural food colorant is provided. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 2, 2020

2020 article

Identification of an SCPL Gene Controlling Anthocyanin Acylation in Carrot (Daucus carota L.) Root

Curaba, J., Bostan, H., Cavagnaro, P. F., Senalik, D., Mengist, M. F., Zhao, Y., … Iorizzo, M. (2020, January 31). Frontiers in Plant Science, Vol. 10.

By: J. Curaba n , H. Bostan n, P. Cavagnaro *, D. Senalik *, M. Mengist  n, Y. Zhao n, P. Simon *, M. Iorizzo n 

Contributors: J. Curaba n , H. Bostan n, P. Cavagnaro *, D. Senalik *, M. Mengist  n, Y. Zhao n, P. Simon *, M. Iorizzo n 

author keywords: Daucus carota L; anthocyanins; acyltransferase; fine mapping; transcriptome; candidate genes
topics (OpenAlex): Plant Gene Expression Analysis; Plant biochemistry and biosynthesis; Photosynthetic Processes and Mechanisms
TL;DR: Strong linkage-mapping and functional evidences are provided for the candidacy of DcSCPL1 as a primary regulator of anthocyanin acylation in carrot storage root. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 10, 2020

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