Works (24)

Updated: July 25th, 2023 05:06

2023 article

Microtubule competition and cell growth recenter the nucleus after anaphase in fission yeast

Bellingham-Johnstun, K., Thorn, A., Belmonte, J., & Laplante, C. (2023, February 1).

Source: ORCID
Added: February 2, 2023

2023 journal article

β-heavy-spectrin stabilizes the constricting contractile ring during cytokinesis

Journal of Cell Biology.

MeSH headings : Actin Cytoskeleton; Actins; Actomyosin; Animals; Caenorhabditis elegans / cytology; Caenorhabditis elegans Proteins / metabolism; Cytokinesis; Formins; Membrane Glycoproteins / metabolism; Membrane Proteins / metabolism; Microfilament Proteins / metabolism; Spectrin / metabolism
Source: ORCID
Added: September 21, 2022

2021 journal article

A mechanical model of early somite segmentation

ISCIENCE, 24(4).

Sources: ORCID, Web Of Science
Added: March 19, 2021

2021 journal article

Mechanical competition alters the cellular interpretation of an endogenous genetic program

JOURNAL OF CELL BIOLOGY, 220(11).

MeSH headings : Actin Cytoskeleton / genetics; Actins / genetics; Actomyosin / genetics; Animals; Cell Shape / genetics; Cytoskeleton / genetics; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Gastrulation / genetics; Mesoderm / physiology
Sources: ORCID, Web Of Science
Added: October 26, 2021

2021 journal article

Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis

CURRENT BIOLOGY, 31(24), 5415-+.

MeSH headings : Actins / metabolism; Actomyosin / metabolism; Animals; Caenorhabditis elegans / metabolism; Cytokinesis; Membrane Glycoproteins; Microfilament Proteins; Spectrin / genetics
Sources: ORCID, Web Of Science
Added: October 19, 2021

2020 article

Cellular mechanisms of chick limb bud morphogenesis

Lesnicar-Pucko, G., Belmonte, J. M., Musy, M., Glazier, J. A., & Sharpe, J. (2020, September 11). (Vol. 9). Vol. 9.

Source: ORCID
Added: September 13, 2020

2020 journal article

CompuCell3D Simulations Reproduce Mesenchymal Cell Migration on Flat Substrates

BIOPHYSICAL JOURNAL, 118(11), 2801–2815.

MeSH headings : Cell Movement; Computer Simulation; Diffusion; Models, Biological; Motion
Sources: ORCID, Web Of Science
Added: June 22, 2020

2020 article

Mechanical competition alters the cellular interpretation of an endogenous genetic programme

Bhide, S., Gombalova, D., Mönke, G., Stegmaier, J., Zinchenko, V., Kreshuk, A., … Leptin, M. (2020, October 15). (Vol. 10). Vol. 10.

Source: ORCID
Added: October 16, 2020

2020 journal article

Parameterizing cell movement when the instantaneous cell migration velocity is ill-defined

Physica A: Statistical Mechanics and Its Applications.

author keywords: Cell migration; Furth equation
Source: ORCID
Added: May 4, 2020

2019 article

A Mechanical Model of Early Somite Segmentation

(2019, October 13).

Source: ORCID
Added: March 1, 2022

2019 journal article

Polarity sorting drives remodeling of actin-myosin networks

Journal of Cell Science.

author keywords: Actin cytoskeleton; Actin-myosin contraction; Active gel; Cell cortex; Myosin end-dwelling; Polarity sorting
MeSH headings : Actin Cytoskeleton / chemistry; Actins / physiology; Actomyosin / physiology; Cell Movement / physiology; Computer Simulation; Cytoskeletal Proteins / physiology; Cytoskeleton / physiology; Models, Biological; Muscle Contraction / physiology; Myosins / physiology
Source: ORCID
Added: February 7, 2019

2018 journal article

A disassembly-driven mechanism explains F-actin-mediated chromosome transport in starfish oocytes

ELife, 7.

MeSH headings : Actins / metabolism; Animals; Biological Transport; Chromosomes / metabolism; Computer Simulation; Meiosis; Models, Biological; Oocytes / physiology; Starfish
Source: ORCID
Added: February 7, 2019

2018 journal article

Fibroblast state switching orchestrates dermal maturation and wound healing

Molecular Systems Biology, 14(8).

By: E. Rognoni*, A. Pisco*, T. Hiratsuka*, K. Sipilä*, J. Belmonte*, S. Mobasseri*, C. Philippeos*, R. Dilão, F. Watt*

author keywords: dermis development; fibroblast states; mathematical modelling; tissue architecture; wound healing
MeSH headings : Animals; Cell Lineage / genetics; Cell Movement / genetics; Cell Proliferation / genetics; Cells, Cultured; Dermis / growth & development; Dermis / metabolism; Extracellular Matrix / genetics; Fibroblasts / cytology; Fibroblasts / metabolism; Humans; Mice; Skin / growth & development; Skin / metabolism; Wound Healing / genetics
Source: ORCID
Added: July 29, 2021

2017 journal article

A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal

Molecular Systems Biology, 13(4), 927.

By: K. Chen*, T. Srinivasan*, K. Tung*, J. Belmonte*, L. Wang*, P. Murthy*, J. Choi*, N. Rakhilin* ...

author keywords: gene editing; intestine stem cell; Notch signaling; organoid; positive feedback
MeSH headings : Animals; Binding Sites; Cell Self Renewal; Feedback, Physiological; Humans; Intestinal Mucosa / metabolism; Intestines / cytology; Mice; Mutation; Organoids / metabolism; Receptor, Notch1 / chemistry; Receptor, Notch1 / genetics; Receptors, G-Protein-Coupled / metabolism; Signal Transduction; Stem Cell Niche; Stochastic Processes; Systems Biology / methods
Source: ORCID
Added: February 7, 2019

2017 journal article

A theory that predicts behaviors of disordered cytoskeletal networks

Molecular Systems Biology, 13(9), 941.

author keywords: actin; active gel; cell cortex; contractility; morphogenesis
MeSH headings : Actomyosin / chemistry; Algorithms; Animals; Cytoskeleton / chemistry; Cytoskeleton / metabolism; Models, Biological; Systems Biology / methods
Source: ORCID
Added: February 7, 2019

2016 journal article

A Liver-Centric Multiscale Modeling Framework for Xenobiotics

PLOS ONE, 11(9), e0162428.

Ed(s): E. Schmidt

MeSH headings : Acetaminophen / pharmacology; Liver / drug effects; Liver / metabolism; Models, Theoretical; Programming Languages; Xenobiotics
Source: ORCID
Added: February 7, 2019

2016 journal article

Filopodial-Tension Model of Convergent-Extension of Tissues

PLOS Computational Biology, 12(6), e1004952.

Ed(s): T. Tusscher

MeSH headings : Animals; Cell Adhesion / physiology; Cell Polarity / physiology; Computer Simulation; Elastic Modulus / physiology; Embryonic Development / physiology; Feedback, Physiological / physiology; Humans; Mechanotransduction, Cellular / physiology; Models, Biological; Pseudopodia / physiology; Stress, Mechanical; Tensile Strength / physiology
Source: ORCID
Added: February 7, 2019

2016 journal article

Large-scale microtubule networks contract quite well

Elife, 5.

MeSH headings : Actins; Dyneins; Microtubules
Source: ORCID
Added: February 7, 2019

2016 journal article

Virtual-tissue computer simulations define the roles of cell adhesion and proliferation in the onset of kidney cystic disease

Molecular Biology of the Cell, 27(22), 3673–3685.

By: J. Belmonte*, S. Clendenon*, G. Oliveira*, M. Swat*, E. Greene*, S. Jeyaraman*, J. Glazier*, R. Bacallao*

MeSH headings : Animals; Cadherins / metabolism; Cell Adhesion / physiology; Cell Culture Techniques; Cell Proliferation / physiology; Computer Simulation / statistics & numerical data; Cysts / metabolism; Humans; Kidney / metabolism; Mutation; Polycystic Kidney, Autosomal Dominant / metabolism; Signal Transduction
Source: ORCID
Added: February 7, 2019

2015 journal article

3D simulations of wet foam coarsening evidence a self similar growth regime

Colloids and Surfaces a-Physicochemical and Engineering Aspects, 473, 109–114.

author keywords: Liquid foams; Foam coarsening; Potts model simulations
Source: ORCID
Added: February 7, 2019

2014 journal article

Somites Without a Clock

Science, 343(6172), 791–795.

MeSH headings : Animals; Bone Morphogenetic Proteins / antagonists & inhibitors; CLOCK Proteins / genetics; Carrier Proteins / pharmacology; Cell Communication; Circadian Clocks / drug effects; Circadian Clocks / genetics; Circadian Clocks / physiology; Gene Expression Regulation, Developmental; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Metabolic Networks and Pathways; Quail; Receptors, Notch / metabolism; Somites / cytology; Somites / drug effects; Somites / growth & development
Source: ORCID
Added: February 7, 2019

2012 journal article

Multi-Scale Modeling of Tissues Using CompuCell3D

Computational Methods in Cell Biology, 110, 325–366.

By: M. Swat*, G. Thomas*, J. Belmonte*, A. Shirinifard*, D. Hmeljak*, J. Glazier*, A. Asthagiri, A. Arkin

MeSH headings : Algorithms; Cell Adhesion; Cell Death; Cell Movement; Cell Proliferation; Chemotaxis; Computer Simulation; Human Umbilical Vein Endothelial Cells / cytology; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Models, Biological; Monte Carlo Method; Neoplasms, Vascular Tissue / blood supply; Neoplasms, Vascular Tissue / pathology; Neovascularization, Pathologic; Software; Thermodynamics; Tissue Engineering; Vascular Endothelial Growth Factor A / metabolism
Source: ORCID
Added: February 7, 2019

2011 journal article

A Multi-cell, Multi-scale Model of Vertebrate Segmentation and Somite Formation

Plos Computational Biology, 7(10).

MeSH headings : Animals; Biological Clocks; Body Patterning; Cell Adhesion; Cell Adhesion Molecules / genetics; Cell Adhesion Molecules / metabolism; Cell Division; Cell Movement; Computational Biology; Fibroblast Growth Factor 8 / genetics; Fibroblast Growth Factor 8 / metabolism; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins / genetics; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / genetics; Membrane Proteins / metabolism; Mesoderm / cytology; Mesoderm / embryology; Mesoderm / metabolism; Models, Biological; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptors, Notch / genetics; Receptors, Notch / metabolism; Signal Transduction; Somites / cytology; Somites / embryology; Somites / metabolism; Wnt3A Protein / genetics; Wnt3A Protein / metabolism
Source: ORCID
Added: February 7, 2019

2008 journal article

Self-propelled particle model for cell-sorting phenomena

Physical Review Letters, 100(24).

MeSH headings : Animals; Cell Adhesion / physiology; Cell Movement / physiology; Hydra / cytology; Hydra / physiology; Models, Biological; Regeneration / physiology
Source: ORCID
Added: February 7, 2019

Employment

Updated: October 13th, 2019 17:06

2018 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Physics

2014 - 2018

European Molecular Biology Laboratory Heidelberg, Baden-Württemberg, DE
Postdoc

Education

Updated: January 4th, 2016 04:22

Indiana University Bloomington Bloomington, IN, US
PhD Physics

Universidade Federal do Rio Grande do Sul Porto Alegre, RS, BR
Master Physics

Universidade Federal do Rio Grande do Sul Porto Alegre, RS, BR
Bachelor Physics

Funding History

Funding history based on the linked ORCID record. Updated: January 4th, 2016 04:30

salary-award January 1, 2015
Embryo-scale characterization and modeling of tissue dynamics during Drosophila gastrulation
EMBL Interdisciplinary Postdoc (EIPOD) Fellowship