Jhon Cores
Works (20)
Updated: July 7th, 2023 21:21
2021 journal article
Exosome-eluting stents for vascular healing after ischaemic injury
NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Drug-Eluting Stents; Endothelial Cells; Endothelium, Vascular; Exosomes; Ischemia; Rats; Stents
Sources: Web Of Science, ORCID
Added: April 6, 2021
2021 journal article
Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair
ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: extrusion; nanovesicles; extracellular vesicles; mesenchymal stem cell; ischemia reperfusion injury
MeSH headings : Animals; Disease Models, Animal; Endothelial Cells / drug effects; Endothelial Cells / pathology; Extracellular Vesicles / chemistry; Fibroblasts / drug effects; Fibroblasts / pathology; Mesenchymal Stem Cells / chemistry; Mesenchymal Stem Cells / cytology; Mice; Myocardial Infarction / drug therapy; Myocardial Infarction / pathology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Nanoparticles / chemistry; Particle Size; Surface Properties
Sources: Web Of Science, ORCID
Added: February 21, 2022
2021 journal article
Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury
NANO TODAY, 39.
co-author countries:
United States of America 🇺🇸
author keywords: Exosomes; Targeting; Myocardial infarction; Platelet membrane; Stem cells
Sources: Web Of Science, ORCID
Added: September 7, 2021
2020 journal article
Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs
ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(11), 6309–6320.
co-author countries:
United States of America 🇺🇸
author keywords: microfluidics; cardiac patch; cardiac stromal cells; myocardial infarction; porcine model
MeSH headings : Animals; Microvessels; Myocardial Infarction / therapy; Myocytes, Cardiac; Neovascularization, Physiologic; Rats; Stromal Cells; Swine
Sources: Web Of Science, ORCID
Added: December 11, 2020
2020 journal article
Dermal exosomes containing miR-218-5p promote hair regeneration by regulating beta-catenin signaling
SCIENCE ADVANCES, 6(30).
co-author countries:
United States of America 🇺🇸
MeSH headings : Cells, Cultured; Exosomes; Hair; Hair Follicle; MicroRNAs / genetics; Regeneration; beta Catenin / genetics
advances.sciencemag.org (publisher PDF)
Sources: Web Of Science, ORCID
Added: August 10, 2020
2020 journal article
Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
NATURE COMMUNICATIONS, 11(1).
co-author countries:
United States of America 🇺🇸
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
Sources: Web Of Science, ORCID
Added: March 23, 2020
2020 journal article
Targeted anti-IL-1 beta platelet microparticles for cardiac detoxing and repair
SCIENCE ADVANCES, 6(6).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Apoptosis; Blood Platelets / metabolism; Cell-Derived Microparticles / metabolism; Cytokines / metabolism; Disease Models, Animal; Humans; Immunohistochemistry; Inflammation Mediators / metabolism; Interleukin-1beta / antagonists & inhibitors; Mice; Models, Biological; Myocardial Infarction / etiology; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocytes, Cardiac / metabolism; Protein Binding; Ventricular Remodeling
Sources: Web Of Science, ORCID
Added: March 2, 2020
2020 journal article
Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs
THERANOSTICS, 10(8), 3474–3487.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: exosome; homing; integrin; doxorubicin; cancer therapy
MeSH headings : Animals; Antibiotics, Antineoplastic / administration & dosage; Antineoplastic Agents / administration & dosage; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / analogs & derivatives; Drug Delivery Systems; Exosomes / metabolism; HeLa Cells; Humans; Mice; Mice, Nude; Polyethylene Glycols / administration & dosage
Sources: Web Of Science, ORCID
Added: March 30, 2020
2019 journal article
Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging
ACS NANO, 13(10), 11273–11282.
co-author countries:
United States of America 🇺🇸
author keywords: needle free injection; dermal fibroblasts; spheroids; exosomes; skin aging; microRNA
MeSH headings : Animals; Biopolymers / metabolism; Cell Proliferation / radiation effects; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Exosomes / metabolism; Fibroblasts / metabolism; Humans; Mice; Mice, Nude; Skin / cytology; Skin / radiation effects; Skin Aging / radiation effects; Spheroids, Cellular / cytology; Spheroids, Cellular / radiation effects; Tissue Inhibitor of Metalloproteinase-1 / metabolism; Transforming Growth Factor beta / metabolism; Tumor Necrosis Factor-alpha / metabolism; Ultraviolet Rays; Wound Healing / radiation effects
Sources: Web Of Science, ORCID
Added: November 11, 2019
2019 journal article
Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury
ADVANCED FUNCTIONAL MATERIALS, 29(4).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
Sources: Web Of Science, ORCID
Added: February 4, 2019
2019 journal article
The role of cellular contact and TGF-beta signaling in the activation of the epithelial mesenchymal transition (EMT)
CELL ADHESION & MIGRATION, 13(1), 63–75.
co-author countries:
United States of America 🇺🇸
author keywords: EMT; TGF-; cellular adhesion; epithelial; mesenchymal; breast carcinoma; colon carcinoma
MeSH headings : Adenocarcinoma / metabolism; Adenocarcinoma / pathology; Breast Neoplasms / metabolism; Breast Neoplasms / pathology; Cell Adhesion; Cell Movement; Colorectal Neoplasms / metabolism; Colorectal Neoplasms / pathology; Epithelial-Mesenchymal Transition / drug effects; Female; Humans; Signal Transduction; Transforming Growth Factor beta / pharmacology; Tumor Cells, Cultured
Sources: Web Of Science, ORCID
Added: June 24, 2019
2019 journal article
microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential
JOURNAL OF CLINICAL INVESTIGATION, 129(6), 2237–2250.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Exosomes / genetics; Exosomes / metabolism; Exosomes / pathology; Female; Heart / physiology; Heart Failure / genetics; Heart Failure / metabolism; Heart Failure / pathology; Human Umbilical Vein Endothelial Cells / metabolism; Human Umbilical Vein Endothelial Cells / pathology; Humans; Male; Mice; MicroRNAs / genetics; MicroRNAs / metabolism; Myocardium / metabolism; Myocardium / pathology; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Neovascularization, Physiologic; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Regeneration; Signal Transduction; Stromal Cells / metabolism; Stromal Cells / pathology
Sources: Web Of Science, ORCID
Added: June 24, 2019
2018 journal article
Concise Review: Is Cardiac Cell Therapy Dead? Embarrassing Trial Outcomes and New Directions for the Future
Stem Cells Translational Medicine, 7(4), 354–359.
co-author countries:
China 🇨🇳 Japan 🇯🇵 New Zealand 🇳🇿 United States of America 🇺🇸
author keywords: Myocardial injury; Stem cell therapy; Synthetic stem cells; Biomaterials
MeSH headings : Animals; Cell- and Tissue-Based Therapy / methods; Heart / physiology; Heart Diseases / therapy; Humans; Regeneration / physiology; Stem Cell Transplantation / methods; Stem Cells / cytology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2018 journal article
Targeted repair of heart injury by stem cells fused with platelet nanovesicles
NATURE BIOMEDICAL ENGINEERING, 2(1), 17–26.
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
A Regenerative Cardiac Patch Formed by Spray Painting of Biomaterials onto the Heart
Tissue Engineering Part C: Methods, 23(3), 146–155.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cardiac patch; platelet fibrin gel; myocardial infarction; regeneration
MeSH headings : Animals; Biocompatible Materials / chemistry; Blood Platelets / metabolism; Fibrin / metabolism; Heart / physiology; Male; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Paintings; Rats; Rats, Sprague-Dawley; Regeneration / physiology
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis
STEM CELLS Translational Medicine, 6(10), 1905–1916.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Fibrosis; Pulmonary; Syngeneic; Allogeneic; Stem cells
MeSH headings : Animals; Bleomycin / toxicity; Cells, Cultured; Female; Lung / cytology; Pulmonary Fibrosis / etiology; Pulmonary Fibrosis / therapy; Rats; Rats, Wistar; Spheroids, Cellular / transplantation; Stem Cell Transplantation / adverse effects; Stem Cell Transplantation / methods; Transplantation, Homologous / adverse effects; Transplantation, Homologous / methods
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
Nature Communications, 8(1).
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / metabolism; Biomimetic Materials / pharmacology; Cell Fractionation; Cell Membrane / chemistry; Cell Membrane / metabolism; Cell Membrane / transplantation; Cell-Derived Microparticles / chemistry; Cell-Derived Microparticles / metabolism; Cell-Derived Microparticles / transplantation; Culture Media, Conditioned / chemistry; Culture Media, Conditioned / isolation & purification; Disease Models, Animal; Gene Expression; Hepatocyte Growth Factor / genetics; Hepatocyte Growth Factor / metabolism; Humans; Injections, Intralesional; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Intercellular Signaling Peptides and Proteins / pharmacology; Male; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / metabolism; Myocardium / pathology; Paracrine Communication; Recovery of Function / drug effects; Stem Cells / cytology; Stem Cells / metabolism; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 journal article
Angiopellosis as an Alternative Mechanism of Cell Extravasation
STEM CELLS, 35(1), 170–180.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2015 journal article
Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis
STEM CELLS TRANSLATIONAL MEDICINE, 4(11), 1265–1274.
co-author countries:
United States of America 🇺🇸
author keywords: Adult lung stem cells; Mesenchymal stem cells; Pulmonary fibrosis; Spheroid cell culture
MeSH headings : Adult; Animals; Antibiotics, Antineoplastic / adverse effects; Antibiotics, Antineoplastic / pharmacology; Bleomycin / adverse effects; Bleomycin / pharmacology; Female; Heterografts; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Mice; Mice, SCID; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / therapy; Regeneration; Spheroids, Cellular / metabolism; Spheroids, Cellular / transplantation
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips
PLOS ONE, 10(11).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Coronary Vessels / surgery; Disease Models, Animal; Ligation; Mice; Myocardial Infarction / etiology; Myocardial Infarction / mortality; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Surgical Instruments; Suture Techniques; Vascular Surgical Procedures
Source: Web Of Science
Added: August 6, 2018
