Jacob Coleman Perry

Works (2)

Updated: April 5th, 2024 17:07

2023 journal article

Comparison of Aptamer Signaling Mechanisms Reveals Disparities in Sensor Response and Strategies to Eliminate False Signals

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 145(22), 12407–12422.

By: O. Alkhamis n, J. Canoura n, C. Willis n, L. Wang n, J. Perry n & Y. Xiao n 

MeSH headings : Aptamers, Nucleotide / chemistry; DNA; DNA, Complementary; Sensitivity and Specificity; SELEX Aptamer Technique / methods; Biosensing Techniques / methods
TL;DR: This work has developed a series of sensors using aptamers for the small-molecule drugs flunixin, fentanyl, and furanyl fentanyl and compares their performance, focusing on their specificity, and demonstrates strategies for improving the sensitivity and specificity of aptamer sensors with the development of a "hybrid beacon". (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: July 19, 2023

2023 article

Suite of Aptamer-Based Sensors for the Detection of Fentanyl and Its Analogues

Canoura, J., Liu, Y., Perry, J., Willis, C., & Xiao, Y. (2023, April 25). ACS SENSORS, Vol. 4.

By: J. Canoura n, Y. Liu n, J. Perry n, C. Willis n & Y. Xiao n 

author keywords: aptamers; fentanyl; analogue; electrochemistry; colorimetry; fluorescence; bioanalytical; sensors
MeSH headings : Humans; United States; Fentanyl; Analgesics, Opioid; Illicit Drugs; Drug Overdose; Immunoassay
TL;DR: A series of new aptamer-based assays and sensors that can detect fentanyl as well as several of its analogues in a reliable, accurate, rapid, and economic manner are developed and foresee the potential for routine use by medical and law enforcement personnel aswell as the general public to aid in rapid and accurate fentanyl identification. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023

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