Jennifer Lynn Davis

2025 article

Pharmacokinetics of Orally Administered Phenazopyridine in Goats With Obstructive Urolithiasis

Mitman, S. L., Mzyk, D. A., Camacho, B. E., Council-Troche, R. M. A., Davis, J., Foster, D. M., & Halleran, J. (2025, June 26). Journal of Veterinary Internal Medicine, Vol. 39.

By: S. Mitmanⁿ, D. Mzykⁿ , B. Camachoⁿ , R. Council-Troche ^*, J. Davisⁿ, D. Fosterⁿ , J. Halleran

author keywords: analgesia; caprine; pharmacology; urolithiasis

MeSH headings : Animals; Goats; Male; Urolithiasis / veterinary; Urolithiasis / drug therapy; Urolithiasis / surgery; Administration, Oral; Prospective Studies; Phenazopyridine / pharmacokinetics; Phenazopyridine / administration & dosage; Phenazopyridine / therapeutic use; Phenazopyridine / blood; Phenazopyridine / urine; Goat Diseases / drug therapy; Half-Life; Area Under Curve

topics (OpenAlex): Anesthesia and Pain Management; Nausea and vomiting management; Urinary Bladder and Prostate Research

10.1111/jvim.70167

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open access via onlinelibrary.wiley.com (publisher PDF)

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UN Sustainable Development Goals Color Wheel

UN Sustainable Development Goal Categories

3. Good Health and Well-being (OpenAlex)

Sources: Web Of Science, ORCID, NC State University Libraries

Added: June 26, 2025

2024 article

Development of a physiologically based pharmacokinetic model for flunixin in cattle and swine following dermal exposure

Wu, X., Chen, Q., Chou, W.-C., Maunsell, F. P., Tell, L. A., Baynes, R. E., … Lin, Z. (2024, October 30). Toxicological Sciences, Vol. 11.

By: X. Wu ^*, Q. Chen ^*, W. Chou ^*, F. Maunsell ^*, L. Tell ^*, R. Baynesⁿ , J. Davis^*, M. Jaberi-Douraki ^*, J. Riviereⁿ, Z. Lin ^*

author keywords: flunixin meglumine; cattle; swine; physiologically based pharmacokinetic (PBPK) modeling; food safety; risk assessment; computational toxicology

MeSH headings : Animals; Clonixin / analogs & derivatives; Clonixin / pharmacokinetics; Cattle; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Administration, Cutaneous; Swine; Models, Biological; Monte Carlo Method; Skin / metabolism; Skin / drug effects; Liver / metabolism; Drug Residues / pharmacokinetics; Skin Absorption; Tissue Distribution

topics (OpenAlex): Animal testing and alternatives; Antibiotics Pharmacokinetics and Efficacy; Veterinary Pharmacology and Anesthesia

10.1093/toxsci/kfae139

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: December 2, 2024

2024 article

Hemadsorption extracorporeal therapy removes cytokines ex vivo in horses

Hobbs, K. J., Davis, J. L., Cooper, B. L., Ueda, Y., Burke, M. J., & Sheats, M. K. (2024, March 14). American Journal of Veterinary Research, Vol. 85.

By: K. Hobbsⁿ , J. Davis^*, B. Cooperⁿ, Y. Uedaⁿ , M. Burkeⁿ & M. Sheatsⁿ

author keywords: extracorporeal; equine; hemadsorption; cytokines; dialysis

MeSH headings : Animals; Horses; Cytokines / metabolism; Cytokines / blood; Lipopolysaccharides; Horse Diseases / therapy; Sepsis / veterinary; Sepsis / therapy; Adsorption; Male; Female; Anti-Bacterial Agents

topics (OpenAlex): Animal health and immunology; Veterinary Equine Medical Research; Mechanical Circulatory Support Devices

10.2460/ajvr.24.01.0022

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open access via avmajournals.avma.org (publisher PDF)

PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: June 17, 2024

2023 article

Development and application of an interactive generic physiologically based pharmacokinetic (igPBPK) model for adult beef cattle and lactating dairy cows to estimate tissue distribution and edible tissue and milk withdrawal intervals for per- and polyfluoroalkyl substances (PFAS)

Chou, W.-C., Tell, L. A., Baynes, R. E., Davis, J. L., Cheng, Y.-H., Maunsell, F. P., … Lin, Z. (2023, September 26). Food and Chemical Toxicology, Vol. 181.

By: W. Chou ^*, L. Tell ^*, R. Baynesⁿ , J. Davis^*, Y. Cheng ^*, F. Maunsell ^*, J. Riviereⁿ, Z. Lin ^*

author keywords: Per-and polyfluoroalkyl substances (PFAS); Chemical residue; Interactive generic physiologically based pharmacokinetic (igPBPK) modeling; Withdrawal interval; Food safety; Risk assessment

MeSH headings : Adult; Humans; Female; Cattle; Animals; Milk / chemistry; Tissue Distribution; Lactation; Fluorocarbons / analysis; Environmental Exposure; Alkanesulfonic Acids / pharmacokinetics; Environmental Pollutants / analysis

topics (OpenAlex): Per- and polyfluoroalkyl substances research; Air Quality and Health Impacts; Toxic Organic Pollutants Impact

10.1016/j.fct.2023.114062

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open access via doi.org (publisher)

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

6. Clean Water and Sanitation (Web of Science)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: November 20, 2023

2023 article

Development of machine learning algorithms to estimate maximum residue limits for veterinary medicines

Zad, N., Tell, L. A., Ramachandran, R. A., Xu, X., Riviere, J. E., Baynes, R., … Jaberi-Douraki, M. (2023, July 27). Food and Chemical Toxicology, Vol. 179.

By: N. Zad ^*, L. Tell ^*, R. Ramachandran ^*, X. Xu ^*, J. Riviereⁿ, R. Baynesⁿ , Z. Lin ^*, F. Maunsell ^*, J. Davis^*, M. Jaberi-Douraki ^*

author keywords: Unestablished MRL; Veterinary drugs; Machine learning; International market and trade; Published commodity (animal organ); Data resampling techniques

MeSH headings : Animals; Humans; Algorithms; Neural Networks, Computer; Machine Learning; Food; Veterinary Drugs; Support Vector Machine

topics (OpenAlex): Computational Drug Discovery Methods; Pesticide Residue Analysis and Safety; Pharmaceutical Quality and Counterfeiting

TL;DR: This study demonstrates unestablished MRLs can be reliably predicted for under-represented food commodity groups using machine learning (ML) and provides the first study to apply ML algorithms in regulatory food animal medicine. (via Semantic Scholar)

10.1016/j.fct.2023.113920

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open access via doi.org (publisher)

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: September 25, 2023

2022 article

A web-based interactive physiologically based pharmacokinetic (iPBPK) model for meloxicam in broiler chickens and laying hens

Yuan, L., Chou, W.-C., Richards, E. D., Tell, L. A., Baynes, R. E., Davis, J. L., … Lin, Z. (2022, August 5). Food and Chemical Toxicology, Vol. 168.

By: L. Yuan^*, W. Chou ^*, E. Richards^*, L. Tell ^*, R. Baynesⁿ , J. Davis^*, J. Riviereⁿ, Z. Lin ^*

author keywords: Meloxicam; Food Animal Residue Avoidance Databank (FARAD); Physiologically based pharmacokinetic (PBPK) modeling; Broiler chicken; Laying hen; Food safety

MeSH headings : Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chickens; Eggs; Female; Internet; Meloxicam

topics (OpenAlex): Analytical Chemistry and Chromatography; Pesticide Residue Analysis and Safety; Antibiotics Pharmacokinetics and Efficacy

TL;DR: The model provides a useful and flexible tool for risk assessment and management of residues for meat and eggs from chickens treated with meloxicam and will serve as a basis for extrapolation to other NSAID drugs and other poultry species to aid animal-derived food safety assessment. (via Semantic Scholar)

10.1016/j.fct.2022.113332

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: December 12, 2022

2022 article

An Interactive Generic Physiologically Based Pharmacokinetic (igPBPK) Modeling Platform to Predict Drug Withdrawal Intervals in Cattle and Swine: A Case Study on Flunixin, Florfenicol, and Penicillin G

Chou, W.-C., Tell, L. A., Baynes, R. E., Davis, J. L., Maunsell, F. P., Riviere, J. E., & Lin, Z. (2022, June 1). Toxicological Sciences, Vol. 6.

By: W. Chou ^*, L. Tell ^*, R. Baynesⁿ , J. Davis^*, F. Maunsell ^*, J. Riviereⁿ, Z. Lin ^*

author keywords: drug residue; Food Animal Residue Avoidance Databank (FARAD); food safety; interactive generic physiologically based pharmacokinetic (igPBPK) model; withdrawal interval (WDI)

MeSH headings : Animals; Cattle; Clonixin / analogs & derivatives; Drug Residues / analysis; Drugs, Generic; Models, Biological; Penicillin G / pharmacokinetics; Swine; Thiamphenicol / analogs & derivatives

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Analytical Chemistry and Chromatography; Pesticide Residue Analysis and Safety

TL;DR: A user-friendly generic PBPK platform that can predict tissue residues and estimate WDIs for multiple drugs including flunixin, florfenicol, and penicillin G in cattle and swine is developed and provides a basis for extrapolating to other drugs and species. (via Semantic Scholar)

10.1093/toxsci/kfac056

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open access via academic.oup.com (publisher PDF)

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: June 20, 2022

2021 journal article

Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine

Journal of the American Veterinary Medical Association, 260(1), 50–55.

By: J. Halleranⁿ, M. Papichⁿ , M. Li ^*, Z. Lin ^*, J. Davis^*, F. Maunsell ^*, J. Riviereⁿ, R. Baynesⁿ , D. Fosterⁿ

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cattle; Drug Residues; Penicillin G Procaine / therapeutic use; Swine

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Pesticide Residue Analysis and Safety; Analytical Methods in Pharmaceuticals

10.2460/javma.21.05.0268

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: February 7, 2022

2020 article

Physiological parameter values for physiologically based pharmacokinetic models in food‐producing animals. Part I: Cattle and swine

Lin, Z., Li, M., Wang, Y. S., Tell, L. A., Baynes, R. E., Davis, J. L., … Riviere, J. E. (2020, April 8). Journal of Veterinary Pharmacology and Therapeutics, Vol. 43, pp. 385–420.

By: Z. Lin ^*, M. Li ^*, Y. Wang ^*, L. Tell ^*, R. Baynesⁿ , J. Davis^*, T. Vickroy^*, J. Riviereⁿ

author keywords: blood flow; food safety; organ weight; physiologically based pharmacokinetic model; withdrawal interval

MeSH headings : Animals; Cattle / physiology; Drug Residues; Models, Biological; Pharmaceutical Preparations / metabolism; Pharmacokinetics; Swine / physiology

topics (OpenAlex): Animal Nutrition and Physiology; Pesticide Residue Analysis and Safety; Animal Behavior and Welfare Studies

TL;DR: These compiled data provide a comprehensive physiological parameter database for developing PBPK models of chemicals in cattle and swine to support animal‐derived food safety assessment and provide a basis to compile data in other food animal species, including goats, sheep, chickens, and turkeys. (via Semantic Scholar)

10.1111/jvp.12861

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PubMed

UN Sustainable Development Goal Categories

13. Climate Action (Web of Science)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: August 31, 2020

2019 article

Comparison of analytical techniques to explain variability in stored drinking water quality and microbial hand contamination of female caregivers in Tanzania

Harris, A. R., Pickering, A. J., Boehm, A. B., Mrisho, M., & Davis, J. (2019, January 1). Environmental Science Processes & Impacts, Vol. 21, pp. 893–903.

By: A. Harrisⁿ , A. Pickering ^*, A. Boehm ^*, M. Mrisho ^* & J. Davis^*

MeSH headings : Caregivers; Colony Count, Microbial; Drinking Water / microbiology; Drinking Water / standards; Escherichia coli / isolation & purification; Female; Hand / microbiology; Housing / standards; Humans; Hygiene / standards; Logistic Models; Models, Statistical; Public Health; Specimen Handling / methods; Specimen Handling / statistics & numerical data; Surveys and Questionnaires; Tanzania; Water Microbiology / standards; Water Quality / standards

topics (OpenAlex): Child Nutrition and Water Access; Fecal contamination and water quality; Food Security and Health in Diverse Populations; Global Maternal and Child Health

TL;DR: This investigation compares the explanatory variables identified in the three different modeling methods to explain hand and water contamination: ordinary least squares regression, logistic regression, and classification tree and suggests there are benefits to using multiple analysis methods to assess relationships in complex systems. (via Semantic Scholar)

10.1039/c8em00460a

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open access via pubs.rsc.org (publisher PDF)

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

6. Clean Water and Sanitation (Web of Science; OpenAlex)

11. Sustainable Cities and Communities (Web of Science)

14. Life Below Water (Web of Science)

Sources: Web Of Science, ORCID, NC State University Libraries

Added: June 17, 2019

2019 article

Impact of bovine respiratory disease on the pharmacokinetics of danofloxacin and tulathromycin in different ages of calves

Mzyk, D. A., Bublitz, C. M., Martinez, M. N., Davis, J. L., Baynes, R. E., & Smith, G. W. (2019, June 24). (D. Gladue, Ed.). PLoS ONE, Vol. 14, p. e0218864.

By: D. Mzykⁿ , C. Bublitzⁿ, M. Martinez ^*, J. Davis^*, R. Baynesⁿ & G. Smithⁿ

Ed(s): D. Gladue

MeSH headings : Age Factors; Animals; Area Under Curve; Bronchoalveolar Lavage Fluid / chemistry; Cattle; Cattle Diseases / drug therapy; Disaccharides / administration & dosage; Disaccharides / pharmacokinetics; Extracellular Fluid / chemistry; Female; Fluoroquinolones / administration & dosage; Fluoroquinolones / pharmacokinetics; Heterocyclic Compounds / administration & dosage; Heterocyclic Compounds / pharmacokinetics; Pasteurella Infections / drug therapy; Pasteurella Infections / veterinary; Pasteurella multocida / pathogenicity; Respiration Disorders / drug therapy; Respiration Disorders / veterinary

topics (OpenAlex): Microbial infections and disease research; Antibiotics Pharmacokinetics and Efficacy; Pneumonia and Respiratory Infections

TL;DR: Age was determined to be a significant covariate for calves administered danofloxacin and tulathromycin for plasma PK parameters and potential reasons for age-related differences on plasma concentration–time profiles and the impact of disease on the partitioning of the drug from the blood to the lungs and ISF as a function of age are explored. (via Semantic Scholar)

10.1371/journal.pone.0218864

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open access via journals.plos.org (publisher PDF)

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: September 30, 2019

2019 journal article

Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration

Archives of Toxicology, 93(7), 1865–1880.

By: M. Li ^*, Y. Cheng ^*, J. Chittendenⁿ, R. Baynesⁿ , L. Tell ^*, J. Davis^*, T. Vickroy^*, J. Riviereⁿ, Z. Lin ^*

author keywords: Flunixin; Interactive physiologically based pharmacokinetic (iPBPK) model; Food safety; Drug residues; Withdrawal intervals (WDIs); Food Animal Residue Avoidance Databank (FARAD)

MeSH headings : Animals; Animals, Domestic / metabolism; Clonixin / administration & dosage; Clonixin / analogs & derivatives; Clonixin / pharmacokinetics; Databases, Factual; Drug Residues / pharmacokinetics; Food Contamination / analysis; Food Contamination / prevention & control; Food Safety / methods; Models, Biological; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics

topics (OpenAlex): Pesticide Residue Analysis and Safety; Antibiotics Pharmacokinetics and Efficacy; Pharmaceutical and Antibiotic Environmental Impacts

TL;DR: A new PBPK model for both cattle and swine after administration of flunixin meglumine was developed and it can be applied to develop new models for other drugs in other food animal species, thereby facilitating the application of P BPK modeling in WDI estimation and food safety assessment. (via Semantic Scholar)

10.1007/s00204-019-02464-z

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 12, 2019

2018 article

Effect of age on plasma protein binding of several veterinary drugs in dairy calves 2

Mzyk, D. A., Bublitz, C. M., Hobgood, G. D., Martinez, M. N., Davis, J. L., Smith, G. W., & Baynes, R. E. (2018, October 13). Research in Veterinary Science, Vol. 121, pp. 59–64.

By: D. Mzykⁿ , C. Bublitzⁿ, G. Hobgoodⁿ, M. Martinez ^*, J. Davis^*, G. Smithⁿ , R. Baynesⁿ

author keywords: Protein binding; Calves; Alpha-1-acid glycoprotein; Albumin

MeSH headings : Age Factors; Animals; Blood Proteins / metabolism; Cattle / metabolism; Protein Binding; Veterinary Drugs / metabolism

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Animal health and immunology

TL;DR: Findings from these calves suggest that age is not an important factor in the binding of these drugs to plasma proteins, and statistically significant age-effects on plasma protein binding were not observed for any of the drugs evaluated. (via Semantic Scholar)

10.1016/j.rvsc.2018.09.004

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: December 17, 2018

2018 article

Extralabel drug use in small ruminants

Martin, K. L., Clapham, M. O., Davis, J. L., Baynes, R. E., Lin, Z., Vickroy, T. W., … Tell, L. A. (2018, October 1). Journal of the American Veterinary Medical Association, Vol. 253, pp. 1001–1009.

By: K. Martin^*, M. Clapham ^*, J. Davis^*, R. Baynesⁿ , Z. Lin ^*, T. Vickroy^*, J. Riviereⁿ, L. Tell

MeSH headings : Animals; Drug Residues; Goat Diseases / drug therapy; Goats; Legislation, Drug; Off-Label Use; Sheep; Sheep Diseases / drug therapy; United States; United States Food and Drug Administration; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics

topics (OpenAlex): Milk Quality and Mastitis in Dairy Cows; Microbial infections and disease research; Animal Diversity and Health Studies

TL;DR: The purpose of this digest is to update a previous FARAD Digest2 concerning small ruminants and provide veterinarians with summary information regarding ELDU in smallRuminants. (via Semantic Scholar)

10.2460/javma.253.8.1001

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: October 16, 2018

2018 article

Oral reserpine administration in horses results in low plasma concentrations that alter platelet biology

Gilbertie, J. M., Davis, J. L., Davidson, G. S., McDonald, A. M., Schirmer, J. M., & Schnabel, L. V. (2018, November 22). Equine Veterinary Journal, Vol. 51, pp. 537–543.

By: J. Gilbertie ⁿ, J. Davis^*, G. Davidsonⁿ, A. McDonaldⁿ, J. Schirmerⁿ & L. Schnabelⁿ

author keywords: horse; reserpine; pharmacokinetics; tranquilisation; platelets; hypercoagulability

MeSH headings : Administration, Oral; Adrenergic Uptake Inhibitors / administration & dosage; Adrenergic Uptake Inhibitors / blood; Adrenergic Uptake Inhibitors / pharmacokinetics; Adrenergic Uptake Inhibitors / pharmacology; Animals; Area Under Curve; Blood Platelets / drug effects; Female; Half-Life; Horses / blood; Male; Reserpine / administration & dosage; Reserpine / blood; Reserpine / pharmacokinetics; Reserpine / pharmacology

topics (OpenAlex): Veterinary Equine Medical Research; Pharmacology and Obesity Treatment; Pain Mechanisms and Treatments

TL;DR: Oral reserpine demonstrates low plasma concentrations and a prolonged half-life in horses and is likely due to serotonin release and re-uptake which primes platelets for activation and thromboxane B2 release. (via Semantic Scholar)

10.1111/evj.13048

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, ORCID, NC State University Libraries

Added: July 22, 2019

2018 article

Pharmacokinetics of Intrarectal Altrenogest in Horses

Ellis, K. E., Dollen, K. A. V., Beachler, T. M., Bailey, C. S., Davis, J. L., & Lyle, S. K. (2018, October 10). Journal of Equine Veterinary Science.

By: K. Ellisⁿ, K. Dollenⁿ, T. Beachlerⁿ, C. Baileyⁿ, J. Davis^* & S. Lyle

author keywords: Horse; Altrenogest; Pharmacokinetics; Intrarectal administration

MeSH headings : Administration, Rectal; Animals; Cross-Over Studies; Female; Horses / metabolism; Pregnancy; Pregnancy Maintenance / drug effects; Trenbolone Acetate / analogs & derivatives; Trenbolone Acetate / pharmacokinetics

topics (OpenAlex): Reproductive Physiology in Livestock; Veterinary Equine Medical Research; Preterm Birth and Chorioamnionitis

TL;DR: Altrenogest is rapidly absorbed following PR administration in the horse and reaches therapeutic concentrations, making this a viable method of treatment in NPO mares, and the decreased bioavailability and shorter detection time suggest 0.088 mg/kg PR q 4–8 hours would be necessary to maintain therapeutic concentrations over a 24‐hour period. (via Semantic Scholar)

10.1016/j.jevs.2018.10.001

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: January 7, 2019

2018 journal article

Photo-triggered release of 5-fluorouracil from a MOF drug delivery vehicle

Chemical Communications, 54(55), 7617–7620.

By: K. Roth Stefaniak ^*, C. Epley^*, J. Novak ^*, M. McAndrew^*, H. Cornell ^*, J. Zhu ^*, D. McDaniel ^*, J. Davis^* ...

MeSH headings : Adsorption; Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Azo Compounds / chemistry; Azo Compounds / radiation effects; Azo Compounds / toxicity; Blood Proteins / chemistry; Cattle; Drug Carriers / chemistry; Drug Carriers / radiation effects; Drug Carriers / toxicity; Fluorouracil / chemistry; Fluorouracil / pharmacology; Humans; MCF-7 Cells; Metal-Organic Frameworks / chemistry; Metal-Organic Frameworks / radiation effects; Metal-Organic Frameworks / toxicity; Mice; Nanoparticles / chemistry; Nanoparticles / radiation effects; Nanoparticles / toxicity; Particle Size; Polyethylene Glycols / chemistry; Polyethylene Glycols / toxicity; Porosity; Ultraviolet Rays

topics (OpenAlex): Metal-Organic Frameworks: Synthesis and Applications; Nanoplatforms for cancer theranostics; Nanoparticle-Based Drug Delivery

TL;DR: A nano metal-organic-framework (nanoMOF) was employed as a first-of-its kind drug delivery vehicle (DDV) for the photo-controlled release of therapeutics with simultaneous breakdown of the carrier into small molecules. (via Semantic Scholar)

10.1039/C8CC01601A

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (OpenAlex)

Source: Crossref

Added: November 24, 2020

2018 article

Treatment of carprofen overdose with therapeutic plasma exchange in a dog

Kjaergaard, A. B., Davis, J. L., & Acierno, M. J. (2018, June 13). Journal of Veterinary Emergency and Critical Care.

By: A. Kjaergaard^*, J. Davisⁿ & M. Acierno ^*

author keywords: canine; kidney injury; NSAID toxicity; plasmapheresis

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / poisoning; Carbazoles / poisoning; Diagnosis, Differential; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Drug Overdose / diagnosis; Drug Overdose / therapy; Drug Overdose / veterinary; Female; Plasma Exchange / veterinary

topics (OpenAlex): Veterinary Pharmacology and Anesthesia; Inflammatory mediators and NSAID effects; Antibiotics Pharmacokinetics and Efficacy

TL;DR: Although recent studies suggest that this particular dog may not have received a toxic dose, a 51% reduction of plasma carprofen concentration was achieved over 180 minutes, and TPE may be beneficial for treatment of dogs that have ingested higher doses. (via Semantic Scholar)

10.1111/vec.12729

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2017 journal article

Feasibility and safety of lumbosacral epiduroscopy in the standing horse

Pferdeheilkunde, 33(4), 401–402.

By: B. Shrauner, A. Bilkslager, J. Davis, N. Campbell, M. Law, M. Lustgarten, T. Prange

Source: NC State University Libraries

Added: August 6, 2018

2017 journal article

Nonsteroidal anti-inflammatory drug associated right dorsal colitis in the horse

Pferdeheilkunde, 33(4), 403–405.

By: J. Davis

Source: NC State University Libraries

Added: August 6, 2018

2017 article

Treatment of ibuprofen intoxication in a dog via therapeutic plasma exchange

Walton, S., Ryan, K. A., Davis, J. L., & Acierno, M. (2017, May 8). Journal of Veterinary Emergency and Critical Care.

By: S. Walton ^*, K. Ryan^*, J. Davisⁿ & M. Acierno ^*

author keywords: NSAID; plasmapheresis; toxicity

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / poisoning; Dog Diseases / chemically induced; Dog Diseases / therapy; Dogs; Drug Overdose / therapy; Drug Overdose / veterinary; Humans; Ibuprofen / poisoning; Male; Plasma Exchange / veterinary

topics (OpenAlex): Inflammatory mediators and NSAID effects; Antibiotics Pharmacokinetics and Efficacy; Veterinary Pharmacology and Anesthesia

TL;DR: An 85% reduction in plasma ib uprofen concentration occurred and recovery from a potentially lethal ingestion of ibuprofen was achieved with TPE and supportive care and the use of TPE should be considered when presented with acute ibUprofen intoxication due to the rapid and efficacious nature of therapy. (via Semantic Scholar)

10.1111/vec.12608

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2017 article

Treatment of meloxicam overdose in a dog via therapeutic plasma exchange

Walton, S., Ryan, K. A., Davis, J. L., & Acierno, M. (2017, May 8). Journal of Veterinary Emergency and Critical Care.

By: S. Walton ^*, K. Ryan^*, J. Davisⁿ & M. Acierno ^*

author keywords: NSAID; overdose; plasmapharesis

MeSH headings : Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / poisoning; Dog Diseases / chemically induced; Dog Diseases / therapy; Dogs; Drug Overdose / therapy; Drug Overdose / veterinary; Female; Injections, Intravenous / veterinary; Meloxicam; Ovariectomy; Plasma Exchange; Plasmapheresis / veterinary; Thiazines / administration & dosage; Thiazines / poisoning; Thiazoles / administration & dosage; Thiazoles / poisoning

topics (OpenAlex): Inflammatory mediators and NSAID effects; Antibiotics Pharmacokinetics and Efficacy; Veterinary Pharmacology and Anesthesia

TL;DR: This report describes the successful use of TPE adjunctively following an acute meloxicam overdose in a dog with therapeutic plasma exchange (TPE). (via Semantic Scholar)

10.1111/vec.12607

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2016 article

Feasibility and safety of lumbosacral epiduroscopy in the standing horse

Shrauner, B., Blikslager, A., Davis, J., Campbell, N., Law, M., Lustgarten, M., & Prange, T. (2016, May 14). Equine Veterinary Journal, Vol. 49, pp. 322–328.

By: B. Shraunerⁿ, A. Blikslagerⁿ , J. Davisⁿ, N. Campbellⁿ, M. Law ⁿ, M. Lustgartenⁿ, T. Prangeⁿ

Contributors: B. Shraunerⁿ, A. Blikslagerⁿ , J. Davisⁿ, N. Campbellⁿ, M. Law ⁿ, M. Lustgartenⁿ, T. Prangeⁿ

author keywords: horse; back pain; hindlimb lameness; spinal nerve; epiduroscopy; endoscopy

MeSH headings : Animals; Endoscopy / methods; Endoscopy / veterinary; Epidural Space / surgery; Female; Horse Diseases / surgery; Horses; Lumbosacral Region / surgery; Male

topics (OpenAlex): Veterinary Equine Medical Research; Spine and Intervertebral Disc Pathology; Musculoskeletal pain and rehabilitation; Veterinary Orthopedics and Neurology

TL;DR: Lumbosacral epiduroscopy can be performed safely in sedated standing horses and may become a valuable diagnostic tool in horses with caudal back or hindlimb pain of unknown origin. (via Semantic Scholar)

10.1111/evj.12591

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, ORCID, NC State University Libraries

Added: August 6, 2018

2016 journal article

Health concerns and management of select veterinary drug residues

Food and Chemical Toxicology, 88, 112–122.

By: R. Baynesⁿ , K. Dedonder ^*, L. Kissell ⁿ, D. Mzykⁿ , T. Marmulak^*, G. Smithⁿ , L. Tell ^*, R. Gehring ^*, J. Davisⁿ, J. Riviere^*

author keywords: Drug; Veterinary; Residue; Adverse; Livestock

MeSH headings : Animals; Carcinogens; Drug Residues / adverse effects; Humans; Veterinary Drugs / chemistry; Veterinary Drugs / metabolism; Veterinary Drugs / pharmacokinetics

topics (OpenAlex): Pharmacological Effects and Assays; Inflammatory mediators and NSAID effects; Pharmaceutical and Antibiotic Environmental Impacts

TL;DR: The aim of this manuscript is to review the potential adverse health effects in humans if exposed to residues of selected veterinary drugs used in food-producing animals and how regulatory and independent organizations manage the risk of these veterinary drugs based on data from human health risk assessments. (via Semantic Scholar)

10.1016/J.FCT.2015.12.020

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open access via manuscript.elsevier.com (publisher PDF)

PubMed

Sources: Crossref, ORCID, NC State University Libraries

Added: February 24, 2020

2016 journal article

Pharmacokinetics of ceftiofur crystalline-free acid in clinically healthy dogs (Canis lupus familiaris)

Journal of the American Association for Laboratory Animal Science, 55(2), 224–229.

By: S. Hooper, S. Korte, S. Giguere, W. Fales, J. Davis & L. Dixon

Source: NC State University Libraries

Added: August 6, 2018

2015 article

Nonsteroidal anti‐inflammatory drug associated right dorsal colitis in the horse

Davis, J. L. (2015, September 8). Equine Veterinary Education.

By: J. Davisⁿ

author keywords: horse; right dorsal colon; adverse drug reaction; protein losing enteropathy; nonsteroidal anti-inflammatory drug

topics (OpenAlex): Veterinary Equine Medical Research; Inflammatory mediators and NSAID effects; Veterinary medicine and infectious diseases

TL;DR: Right dorsal colitis in horses is a disease characterised by mucosal ulceration and oedema that is localised to the right dorsal colon that is considered one of the more severe adverse effects associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly phenylbutazone. (via Semantic Scholar)

10.1111/eve.12454

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2015 journal article

Opinions of clinical veterinarians at a US veterinary teaching hospital regarding antimicrobial use and antimicrobial-resistant infections

Journal of the American Veterinary Medical Association, 247(8), 938–944.

By: M. Jacob^*, J. Hoppin^* , N. Steers^*, J. Davis^*, G. Davidson^*, B. Hansen^*, K. Lunn^* , K. Murphy^* , M. Papich^*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteria / drug effects; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Cross-Sectional Studies; Data Collection; Drug Resistance, Bacterial; Education, Veterinary; Female; Hospitals, Animal; Humans; Male; Professional Practice; Schools, Veterinary; United States; Veterinarians

topics (OpenAlex): Veterinary Practice and Education Studies; Bacterial Identification and Susceptibility Testing; Antibiotic Use and Resistance

TL;DR: Findings indicated that veterinarians at this teaching hospital were concerned about antimicrobial resistance, thought antimicrobials were overprescribed, and supported restricting use of certain antimicrobial classes in companion animals. (via Semantic Scholar)

10.2460/javma.247.8.938

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, Crossref

Added: August 6, 2018

2015 journal article

Use of Alprazolam to Facilitate Mare-Foal Bonding in an Aggressive Postparturient Mare

Journal of Veterinary Internal Medicine, 29(1), 414–416.

By: D. Wong ^*, C. Alcott^*, J. Davisⁿ, K. Hepworth^* , L. Wulf^* & J. Coetzee ^*

author keywords: Behavior; Horse; Maternal; Milk; Neonate; Nursing; Xanax

MeSH headings : Aggression / drug effects; Alprazolam / pharmacology; Animals; Animals, Newborn; Animals, Suckling; Behavior, Animal / drug effects; Female; GABA Modulators / pharmacology; Horses / physiology; Male; Maternal Behavior / drug effects; Postpartum Period

topics (OpenAlex): Veterinary Equine Medical Research; Reproductive Physiology in Livestock; Animal health and immunology

TL;DR: A healthy 11-year old, 577 kg maiden Quarter Horse mare was examined at the Lloyd Veterinary Medical Center with a 4-day old colt because the mare would bite or kick the foal when thefoal attempted to suckle, and the m Mare consistently demonstrated aggressive behavior toward the foals. (via Semantic Scholar)

10.1111/jvim.12510

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2014 article

Haemoperitoneum in a pregnant mare with an ovarian haematoma

Beachler, T. M., Bailey, C. S., McKelvey, K. A., Davis, J. L., Edwards, A., Diaw, M., … Whitacre, M. D. (2014, July 13). Equine Veterinary Education.

By: T. Beachlerⁿ, C. Baileyⁿ, K. McKelveyⁿ, J. Davisⁿ, A. Edwardsⁿ, M. Diaw ⁿ, J. Vasgaardⁿ, M. Whitacreⁿ

author keywords: horse; haemoperitoneum; pregnancy; ovary; haematoma

topics (OpenAlex): Reproductive Physiology in Livestock; Veterinary Equine Medical Research; Animal health and immunology

TL;DR: An unusual case of haemoperitoneum in a pregnant mare attributed to a unilateral ovarian haematoma during early gestation is described, where the mare maintained her pregnancy to term and delivered a live colt. (via Semantic Scholar)

10.1111/eve.12211

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2014 journal article

Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses

Journal of Veterinary Pharmacology and Therapeutics, 38(3), 249–256.

By: B. Hollandⁿ, C. Fogleⁿ , A. Blikslagerⁿ , A. Curlingⁿ, B. Barlowⁿ, J. Schirmerⁿ, J. Davisⁿ

Contributors: B. Hollandⁿ, C. Fogleⁿ , A. Blikslagerⁿ , A. Curlingⁿ, B. Barlowⁿ, J. Schirmerⁿ, J. Davisⁿ

MeSH headings : 4-Butyrolactone / administration & dosage; 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / blood; 4-Butyrolactone / pharmacokinetics; 4-Butyrolactone / pharmacology; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Cross-Over Studies; Dinoprostone / blood; Horses / metabolism; Injections, Intravenous / veterinary; Ointments; Sulfones / administration & dosage; Sulfones / blood; Sulfones / pharmacokinetics; Sulfones / pharmacology; Tablets; Thromboxane B2 / blood

topics (OpenAlex): Inflammatory mediators and NSAID effects; Coccidia and coccidiosis research; Neuropeptides and Animal Physiology

TL;DR: This study indicates a lack of bioequivalence between the oral formulations of firocoxib when administered as a single dose to healthy horses, as well as a higher Cmax, shorter Tmax, and greater AUC for the paste compared to the tablet. (via Semantic Scholar)

10.1111/jvp.12177

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, Crossref, ORCID, NC State University Libraries

Added: August 6, 2018

2014 journal article

Pharmacokinetics and physiologic effects of alprazolam after a single oral dose in healthy mares

Journal of Veterinary Pharmacology and Therapeutics, 38(3), 301–304.

By: D. Wong ^*, J. Davisⁿ, C. Alcott^*, K. Hepworth-Warren^* , N. Galow-Kersh^*, S. Rice ^*, J. Coetzee ^*

MeSH headings : Administration, Oral; Alprazolam / administration & dosage; Alprazolam / analogs & derivatives; Alprazolam / blood; Alprazolam / pharmacokinetics; Alprazolam / pharmacology; Animals; Ataxia / chemically induced; Ataxia / veterinary; Conscious Sedation / methods; Conscious Sedation / veterinary; Female; Horses / metabolism; Hypnotics and Sedatives / administration & dosage; Hypnotics and Sedatives / blood; Hypnotics and Sedatives / pharmacokinetics; Hypnotics and Sedatives / pharmacology

topics (OpenAlex): Veterinary Pharmacology and Anesthesia; Antibiotics Pharmacokinetics and Efficacy; Veterinary Equine Medical Research

TL;DR: Oral alprazolam tablets were absorbed in adult horses and no clinically relevant adverse events were observed, and further evaluation of repeated dosing and safety of administration of alpazolam to horses is warranted. (via Semantic Scholar)

10.1111/jvp.12192

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2014 article

Pharmacokinetics of danofloxacin andN‐desmethyldanofloxacin in adult horses and their concentration in synovial fluid

Lopez, B. S., Giguère, S., Berghaus, L. J., Mullins, M. A., & Davis, J. L. (2014, September 16). Journal of Veterinary Pharmacology and Therapeutics.

By: B. Lopez ^*, S. Giguère ^*, L. Berghaus ^*, M. Mullins^* & J. Davisⁿ

MeSH headings : Animals; Area Under Curve; Biological Availability; Female; Fluoroquinolones / blood; Fluoroquinolones / chemistry; Fluoroquinolones / metabolism; Fluoroquinolones / pharmacokinetics; Half-Life; Horses / blood; Injections, Intramuscular; Injections, Intravenous; Quinolones / blood; Quinolones / chemistry; Quinolones / metabolism; Quinolones / pharmacokinetics; Synovial Fluid / chemistry

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Bacterial Identification and Susceptibility Testing; Antibiotic Resistance in Bacteria

TL;DR: Monte Carlo simulations indicated that danofloxacin would be predicted to be effective against bacteria with a minimum inhibitory concentration (MIC) ≤0.25 μg/mL for i.m. and i.v. administration and 0.12 μg/ mL for oral administration to maintain an area under the curve:MIC ratio ≥50. (via Semantic Scholar)

10.1111/jvp.12152

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2013 article

Effects of quinapril on angiotensin converting enzyme and plasma renin activity as well as pharmacokinetic parameters of quinapril and its active metabolite, quinaprilat, after intravenous and oral administration to mature horses

Davis, J. L., Kruger, K., LaFevers, D. H., Barlow, B. M., Schirmer, J. M., & Breuhaus, B. A. (2013, November 1). Equine Veterinary Journal, Vol. 46, pp. 729–733.

By: J. Davisⁿ, K. Krugerⁿ, D. LaFeversⁿ, B. Barlowⁿ, J. Schirmerⁿ & B. Breuhausⁿ

author keywords: horse; angiotensin converting enzyme; renin; mitral insufficiency

MeSH headings : Administration, Intravenous; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors / blood; Angiotensin-Converting Enzyme Inhibitors / metabolism; Angiotensin-Converting Enzyme Inhibitors / pharmacokinetics; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Area Under Curve; Gene Expression Regulation, Enzymologic; Half-Life; Horses / blood; Horses / metabolism; Peptidyl-Dipeptidase A / blood; Peptidyl-Dipeptidase A / genetics; Peptidyl-Dipeptidase A / metabolism; Quinapril; Renin / blood; Tetrahydroisoquinolines / blood; Tetrahydroisoquinolines / metabolism; Tetrahydroisoquinolines / pharmacokinetics; Tetrahydroisoquinolines / pharmacology

topics (OpenAlex): Renin-Angiotensin System Studies; Pharmacological Effects and Assays; Heart Failure Treatment and Management

TL;DR: Results suggest that, despite low plasma concentrations, quinapril has sufficient oral absorption to produce inhibition of ACE in healthy horses and provides a potential treatment alternative for horses with cardiovascular and renal disease. (via Semantic Scholar)

10.1111/evj.12206

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2013 article

Management and complications associated with treatment of cervical oesophageal perforations in horses

Kruger, K., & Davis, J. L. (2013, March 12). Equine Veterinary Education.

By: K. Krugerⁿ & J. Davisⁿ

author keywords: horse; oesophageal perforation; enteral nutrition

topics (OpenAlex): Veterinary Equine Medical Research; Animal health and immunology; Pediatric health and respiratory diseases

TL;DR: With surgical debridement and adequate supportive care, oesophageal perforation cases can have a fair to good long-term survival, although chronic complications can occur, therapy is prolonged, and a significant economic commitment is required. (via Semantic Scholar)

10.1111/eve.12020

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2013 article

Pharmacokinetics and safety of firocoxib after oral administration of repeated consecutive doses to neonatal foals

Hovanessian, N., Davis, J. L., McKenzie, H. C., Hodgson, J. L., Hodgson, D. R., & Crisman, M. V. (2013, October 8). Journal of Veterinary Pharmacology and Therapeutics.

By: N. Hovanessian^*, J. Davisⁿ, H. McKenzie ^*, J. Hodgson ^*, D. Hodgson ^* & M. Crisman ^*

MeSH headings : 4-Butyrolactone / administration & dosage; 4-Butyrolactone / adverse effects; 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / blood; 4-Butyrolactone / pharmacokinetics; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Drug Administration Schedule; Horses / blood; Horses / metabolism; Sulfones / administration & dosage; Sulfones / adverse effects; Sulfones / blood; Sulfones / pharmacokinetics

topics (OpenAlex): Inflammatory mediators and NSAID effects; Pharmacogenetics and Drug Metabolism; Antibiotics Pharmacokinetics and Efficacy

TL;DR: It is demonstrated that firocoxib is absorbed in neonatal foals with no demonstrable adverse effects after repeated doses of 0.1 mg/kg. (via Semantic Scholar)

10.1111/jvp.12082

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2013 article

Pharmacokinetics of tobramycin following intravenous, intramuscular, and intra‐articular administration in healthy horses

Newman, J. C., Prange, T., Jennings, S., Barlow, B. M., & Davis, J. L. (2013, March 26). Journal of Veterinary Pharmacology and Therapeutics, Vol. 36, pp. 532–541.

By: J. Newmanⁿ, T. Prangeⁿ , S. Jenningsⁿ, B. Barlowⁿ & J. Davisⁿ

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Female; Half-Life; Horses / blood; Injections, Intra-Articular; Injections, Intramuscular; Injections, Intravenous; Microbial Sensitivity Tests; Tobramycin / administration & dosage; Tobramycin / blood; Tobramycin / pharmacokinetics

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Microbial infections and disease research; Veterinary medicine and infectious diseases

TL;DR: Tobramycin IA resulted in a mild chemical synovitis as evidenced by an increase in synovial fluid cell count and total protein, but appeared to be safe for administration. (via Semantic Scholar)

10.1111/jvp.12048

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2013 article

Plasma and pulmonary pharmacokinetics of desfuroylceftiofur acetamide after weekly administration of ceftiofur crystalline free acid to adult horses

Fultz, L., Giguère, S., Berghaus, L. J., & Davis, J. L. (2013, May 17). Equine Veterinary Journal.

By: L. Fultz^*, S. Giguère ^*, L. Berghaus ^* & J. Davisⁿ

author keywords: Excede; cephalosporin; horse; ceftiofur

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Cephalosporins / administration & dosage; Cephalosporins / blood; Cephalosporins / metabolism; Cephalosporins / pharmacokinetics; Drug Administration Schedule; Female; Half-Life; Horses / blood; Horses / metabolism; Lung / metabolism

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Antibiotic Resistance in Bacteria; Pneumonia and Respiratory Infections

10.1111/evj.12107

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2013 article

Septic funiculitis caused by S treptococcus equi subspecies equi infection with associated immune‐mediated haemolytic anaemia

Caniglia, C. J., Davis, J. L., Schott, H. C., & Brakenhoff, J. E. (2013, December 10). Equine Veterinary Education.

By: C. Caniglia^*, J. Davisⁿ, H. Schott^* & J. Brakenhoff^*

author keywords: horse; castration; septic funiculitis; immune-mediated haemolytic anaemia; azathioprine

topics (OpenAlex): Streptococcal Infections and Treatments; Diphtheria, Corynebacterium, and Tetanus; Bacterial Identification and Susceptibility Testing

TL;DR: A 2-year-old Quarter Horse gelding presented for anaemia, icterus, depression and intermittent colic 2 weeks after routine castration and a blood transfusion was required to facilitate general anaesthesia for surgical excision of the septic funiculitis. (via Semantic Scholar)

10.1111/eve.12116

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2012 article

Comparative pharmacokinetics of desfuroylceftiofur acetamide after intramuscular versus subcutaneous administration of ceftiofur crystalline free acid to adult horses

Fultz, L., Giguère, S., Berghaus, L. J., & Davis, J. L. (2012, December 13). Journal of Veterinary Pharmacology and Therapeutics.

By: L. Fultz^*, S. Giguère ^*, L. Berghaus ^* & J. Davisⁿ

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Cephalosporins / administration & dosage; Cephalosporins / pharmacokinetics; Female; Half-Life; Horses / blood; Horses / metabolism; Injections, Intramuscular / veterinary; Injections, Subcutaneous / veterinary; Statistics as Topic

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Antibiotic Resistance in Bacteria; Drug Transport and Resistance Mechanisms

TL;DR: This study hypothesized that SC administration of CCFA to adult horses will be well tolerated and result in therapeutic plasma concentrations, and sought to compare the size of visible injection site swellings after administration by the two routes of administration. (via Semantic Scholar)

10.1111/jvp.12030

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2012 article

Pharmacokinetics of a continuous rate infusion of ceftiofur sodium in normal foals

WEARN, J. M. G., DAVIS, J. L., HODGSON, D. R., RAFFETTO, J. A., & CRISMAN, M. V. (2012, May 21). Journal of Veterinary Pharmacology and Therapeutics.

By: J. Wearn ^*, J. Davisⁿ, D. Hodgson ^*, J. Raffetto^* & M. Crisman ^*

MeSH headings : Animals; Animals, Newborn / blood; Animals, Newborn / metabolism; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Cephalosporins / administration & dosage; Cephalosporins / blood; Cephalosporins / pharmacokinetics; Female; Horses / blood; Horses / metabolism; Infusions, Intravenous / veterinary; Male

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Antibiotic Resistance in Bacteria; Analytical Methods in Pharmaceuticals

TL;DR: Ceftiofur sodium, a third-generation cephalosporin antimicrobial, has in vitro efficacy against many bacterial organisms cultured from septicemic equine neonates and has a period of post-antibiotic effect and post-Antibiotic leukocyte enhancement. (via Semantic Scholar)

10.1111/j.1365-2885.2012.01403.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2012 article

Sustained-Release Celecoxib from Incubated Acrylic Intraocular Lenses Suppresses Lens Epithelial Cell Growth in an Ex Vivo Model of Posterior Capsule Opacity

Davis, J. L., Yi, N. Y., Salmon, J. H., Charlton, A. N., Colitz, C. M. H., & Gilger, B. C. (2012, February 28). Journal of Ocular Pharmacology and Therapeutics, Vol. 28, pp. 359–368.

By: J. Davisⁿ, N. Yiⁿ, J. Salmonⁿ, A. Charltonⁿ, C. Colitzⁿ & B. Gilgerⁿ

MeSH headings : Animals; Cataract Extraction; Celecoxib; Corneal Opacity / pathology; Corneal Opacity / prevention & control; Cyclooxygenase 2 Inhibitors / administration & dosage; Cyclooxygenase 2 Inhibitors / pharmacokinetics; Cyclooxygenase 2 Inhibitors / therapeutic use; Delayed-Action Preparations; Dogs; Epithelial Cells / drug effects; Epithelium / drug effects; Epithelium / growth & development; In Vitro Techniques; Lens, Crystalline / cytology; Lens, Crystalline / drug effects; Lens, Crystalline / growth & development; Lenses, Intraocular; Polymethyl Methacrylate; Posterior Capsule of the Lens / cytology; Posterior Capsule of the Lens / drug effects; Posterior Capsule of the Lens / pathology; Postoperative Complications / pathology; Postoperative Complications / prevention & control; Pyrazoles / administration & dosage; Pyrazoles / pharmacokinetics; Pyrazoles / therapeutic use; Sulfonamides / administration & dosage; Sulfonamides / pharmacokinetics; Sulfonamides / therapeutic use

topics (OpenAlex): Intraocular Surgery and Lenses; Anesthesia and Pain Management; Inflammatory mediators and NSAID effects

TL;DR: A 4-day treatment of LCs with a concentration of 20 μM CXB may effectively prevent PCO and further studies are needed to determine whether C XB-incubated IOLs can effectively prevent the development of PCO in vivo. (via Semantic Scholar)

10.1089/jop.2011.0196

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open access via europepmc.org (repository)

PubMed

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2011 journal article

Aqueous humor and plasma concentrations of a compounded 0.2% solution of terbinafine following topical ocular administration to normal equine eyes

Veterinary Ophthalmology, 14(1), 41–47.

By: A. Clodeⁿ, J. Davisⁿ, G. Davidsonⁿ, J. Salmonⁿ, H. Lafeversⁿ & B. Gilgerⁿ

author keywords: aqueous humor; equine; keratomycosis; terbinafine

MeSH headings : Absorption; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / analysis; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Aqueous Humor / chemistry; Chromatography, High Pressure Liquid / veterinary; Cornea / metabolism; Female; Horses / metabolism; Male; Naphthalenes / administration & dosage; Naphthalenes / analysis; Naphthalenes / blood; Naphthalenes / pharmacokinetics; Ophthalmic Solutions; Terbinafine

topics (OpenAlex): Ocular Infections and Treatments; Ocular Surface and Contact Lens; Antimicrobial Peptides and Activities

TL;DR: Topical ocular administration of compounded 0.2% terbinafine solution does not result in detectable AH or plasma levels following administration to normal equine eyes, suggesting its use for deep corneal or intraocular fungal infections in equine ophthalmology may be limited. (via Semantic Scholar)

10.1111/j.1463-5224.2010.00841.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2011 article

Clinical and Immunomodulating Effects of Ketamine in Horses with Experimental Endotoxemia

Alcott, C. J., Sponseller, B. A., Wong, D. M., Davis, J. L., Soliman, A. M., Wang, C., & Hsu, W. (2011, July 1). Journal of Veterinary Internal Medicine.

By: C. Alcott^*, B. Sponseller ^*, D. Wong ^*, J. Davisⁿ, A. Soliman ^*, C. Wang ^*, W. Hsu ^*

author keywords: Horses; Immunomodulation; Lipopolysaccharide; Subanesthetic ketamine; Thromboxane; Tumor necrosis factor-alpha

MeSH headings : Animals; Area Under Curve; Body Temperature / drug effects; Endotoxemia / drug therapy; Endotoxemia / immunology; Endotoxemia / veterinary; Female; Heart Rate / drug effects; Horse Diseases / drug therapy; Horse Diseases / immunology; Horses; Immunologic Factors / administration & dosage; Ketamine / administration & dosage; Lipopolysaccharides / administration & dosage; Random Allocation; Respiration / drug effects; Statistics, Nonparametric; Thromboxane B2 / blood; Thromboxane B2 / immunology; Tumor Necrosis Factor-alpha / blood; Tumor Necrosis Factor-alpha / immunology

topics (OpenAlex): Immune Response and Inflammation; Veterinary Pharmacology and Anesthesia; Veterinary Equine Medical Research

TL;DR: A significant effect on the clinical or immunologic response to LPS administration, as assessed by clinical observation, hematological parameters, and TNF-α and TXB(2) production, was not identified in healthy horses with the subanesthetic dose of racemic ketamine utilized in this study. (via Semantic Scholar)

10.1111/j.1939-1676.2011.0749.x

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open access via lib.dr.iastate.edu (repository)

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2011 journal article

Failure of nebulized irritant, acidic, or hypotonic solutions or external mechanical stimulation of the trachea to consistently induce coughing in healthy, awake dogs

Canadian Journal of Veterinary Research, 75(3), 228–232.

By: T. Boyle, E. Hawkins , J. Davis & I. Robertson

Source: NC State University Libraries

Added: August 6, 2018

2011 article

Intravenous and sublingual buprenorphine in horses: pharmacokinetics and influence of sampling site

Messenger, K. M., Davis, J. L., LaFevers, D. H., Barlow, B. M., & Posner, L. P. (2011, April 19). Veterinary Anaesthesia and Analgesia.

By: K. Messenger ⁿ, J. Davisⁿ, D. LaFeversⁿ, B. Barlowⁿ & L. Posnerⁿ

author keywords: analgesia; buprenorphine; equine; opioids; pharmacokinetics; sampling site

MeSH headings : Administration, Sublingual; Analgesics, Opioid / administration & dosage; Analgesics, Opioid / blood; Analgesics, Opioid / pharmacokinetics; Animals; Biological Availability; Blood Chemical Analysis / methods; Blood Chemical Analysis / veterinary; Buprenorphine / administration & dosage; Buprenorphine / analogs & derivatives; Buprenorphine / blood; Buprenorphine / pharmacokinetics; Cross-Over Studies; Horses / metabolism; Injections, Intravenous / veterinary; Jugular Veins; Male; Prospective Studies

topics (OpenAlex): Veterinary Pharmacology and Anesthesia; Pharmacological Effects and Assays; Veterinary Equine Medical Research

TL;DR: Buprenorphine has a long plasma half-life and results in plasma concentrations that are consistent with analgesia in other species for up to 4 hours following IV administration of this dose in horses. (via Semantic Scholar)

10.1111/j.1467-2995.2011.00613.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2011 article

Motility of the equine gastrointestinal tract: Physiology and pharmacotherapy

Wong, D. M., Davis, J. L., & White, N. A. (2011, January 20). Equine Veterinary Education.

By: D. Wong ⁿ, J. Davisⁿ & N. White ⁿ

author keywords: horse; intestine; colic; prokinetic; ileus

topics (OpenAlex): Veterinary Equine Medical Research; Gastrointestinal motility and disorders; Animal health and immunology

TL;DR: A brief review of the anatomy and physiology of the GI tract in the horse is provided and medications available to the equine veterinarian that may potentially promote intestinal motility are reviewed. (via Semantic Scholar)

10.1111/j.2042-3292.2010.00173.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2011 journal article

Pharmacokinetics of intravenous and intramuscular buprenorphine in the horse

Journal of Veterinary Pharmacology and Therapeutics, 35(1), 52–58.

By: J. Davisⁿ, K. Messenger^*, D. Lafevers^*, B. Barlowⁿ & L. Posner^*

MeSH headings : Analgesics, Opioid / administration & dosage; Analgesics, Opioid / blood; Analgesics, Opioid / pharmacokinetics; Animals; Area Under Curve; Buprenorphine / administration & dosage; Buprenorphine / blood; Buprenorphine / pharmacokinetics; Cross-Over Studies; Female; Half-Life; Horses / blood; Horses / metabolism; Injections, Intramuscular; Injections, Intravenous; Male

topics (OpenAlex): Veterinary Pharmacology and Anesthesia; Pharmacological Effects and Assays; Veterinary Equine Medical Research

TL;DR: Buprenorphine has a moderate T(1/2) in the horse and was detected at concentrations expected to be therapeutic in other species after i.v. and i.m. administration of 0.005 mg/kg. (via Semantic Scholar)

10.1111/j.1365-2885.2011.01284.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2011 article

Pharmacokinetics of pioglitazone after multiple oral dose administration in horses

WEARN, J. M. G., CRISMAN, M. V., DAVIS, J. L., GEOR, R. J., HODGSON, D. R., SUAGEE, J. K., … McCUTCHEON, L. J. (2011, April 14). Journal of Veterinary Pharmacology and Therapeutics.

By: J. Wearn ^*, M. Crisman ^*, J. Davisⁿ, R. Geor ^*, D. Hodgson ^*, J. Suagee ^*, M. Ashraf Khorassani^*, L. McCUTCHEON^*

MeSH headings : Administration, Oral; Animals; Chromatography, High Pressure Liquid / veterinary; Drug Administration Schedule / veterinary; Female; Half-Life; Horses / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / pharmacokinetics; Pioglitazone; Tablets; Tandem Mass Spectrometry / veterinary; Thiazolidinediones / administration & dosage; Thiazolidinediones / pharmacokinetics

topics (OpenAlex): Pharmacology and Obesity Treatment; Veterinary Equine Medical Research; Pharmacogenetics and Drug Metabolism

TL;DR: It is shown that in healthy horses, pioglitazone administered at a daily oral dose of 1 mg/kg results in plasma concentrations and total drug exposure approximating, but slightly below, those considered therapeutic in humans. (via Semantic Scholar)

10.1111/j.1365-2885.2010.01217.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2011 article

Ronidazole pharmacokinetics after intravenous and oral immediate-release capsule administration in healthy cats

LeVine, D. N., Papich, M. G., Gookin, J. L., Davidson, G. S., Davis, J. L., & Hayes, R. B. (2011, January 16). Journal of Feline Medicine and Surgery, Vol. 13, pp. 244–250.

By: D. LeVineⁿ, M. Papichⁿ , J. Gookinⁿ , G. Davidsonⁿ, J. Davisⁿ & R. Hayesⁿ

MeSH headings : Administration, Oral; Animals; Antiprotozoal Agents / administration & dosage; Antiprotozoal Agents / pharmacokinetics; Biological Availability; Cat Diseases / drug therapy; Cats / metabolism; Cross-Over Studies; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Metabolic Clearance Rate; Protozoan Infections, Animal / drug therapy; Random Allocation; Ronidazole / administration & dosage; Ronidazole / pharmacokinetics; Tritrichomonas foetus / drug effects

topics (OpenAlex): Reproductive tract infections research; Coccidia and coccidiosis research; Herpesvirus Infections and Treatments

TL;DR: The high oral bioavailability of RDZ and slow elimination may predispose cats to neurotoxicity with twice-daily administration, and less frequent administration should be considered for further study of effective treatment of T foetus-infected cats. (via Semantic Scholar)

10.1016/j.jfms.2010.12.001

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

5. Gender Equality (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2010 journal article

Aqueous humor and plasma concentrations of ciprofloxacin and moxifloxacin following topical ocular administration in ophthalmologically normal horses

American Journal of Veterinary Research, 71(5), 564–569.

By: A. Clodeⁿ, J. Davis^*, J. Salmon^*, H. LaFevers^* & B. Gilger^*

MeSH headings : Administration, Oral; Administration, Topical; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / metabolism; Aqueous Humor / metabolism; Aza Compounds / administration & dosage; Aza Compounds / blood; Aza Compounds / metabolism; Ciprofloxacin / administration & dosage; Ciprofloxacin / blood; Ciprofloxacin / metabolism; Female; Fluoroquinolones; Horses / blood; Horses / metabolism; Male; Moxifloxacin; Orchiectomy / veterinary; Quinolines / administration & dosage; Quinolines / blood; Quinolines / metabolism

topics (OpenAlex): Ocular Infections and Treatments; Antibiotics Pharmacokinetics and Efficacy; Intraocular Surgery and Lenses

TL;DR: Moxifloxacin was better able to penetrate healthy equine corneas and reach measurable AH concentrations than was ciprofloxacIn, suggesting moxif loxac in might be of greater value in the treatment of deep corneal or intraocular bacterial infections caused by susceptible organisms. (via Semantic Scholar)

10.2460/ajvr.71.5.564

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2010 article

Differential heat stability of amphenicols characterized by structural degradation, mass spectrometry and antimicrobial activity

Franje, C. A., Chang, S.-K., Shyu, C.-L., Davis, J. L., Lee, Y.-W., Lee, R.-J., … Chou, C.-C. (2010, June 21). Journal of Pharmaceutical and Biomedical Analysis.

By: C. Franje^*, S. Chang^*, C. Shyu^*, J. Davisⁿ, Y. Lee^*, R. Lee^*, C. Chang ^*, C. Chou ^*

author keywords: Amphenicol; Capillary electrophoresis; Heat stability; GC-MS; Minimum inhibitory concentration

MeSH headings : Anti-Bacterial Agents / analysis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Chloramphenicol / analysis; Chloramphenicol / chemistry; Chloramphenicol / pharmacology; Drug Stability; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry / methods; Hot Temperature; Microbial Sensitivity Tests; Microwaves; Thiamphenicol / analogs & derivatives; Thiamphenicol / analysis; Thiamphenicol / chemistry; Thiamphenicol / pharmacology

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Pharmaceutical and Antibiotic Environmental Impacts; Phenothiazines and Benzothiazines Synthesis and Activities

TL;DR: Despite close similarity in structure; amphenicols exhibited differential behavior toward heating degradation in solutions and protein matrices, and heating treatment may generate product with antimicrobial activity (FF to TAP), therefore, heating of amphenicol residues in food cannot always be assumed safe. (via Semantic Scholar)

10.1016/j.jpba.2010.06.013

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UN Sustainable Development Goal Categories

6. Clean Water and Sanitation (OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2010 article

Efficacy and Pharmacokinetics of Pantoprazole in Alpacas

Smith, G. W., Davis, J. L., Smith, S. M., Gerard, M. P., Campbell, N. B., & Foster, D. M. (2010, April 7). Journal of Veterinary Internal Medicine, Vol. 24, pp. 949–955.

By: G. Smithⁿ , J. Davisⁿ, S. Smithⁿ, M. Gerardⁿ , N. Campbellⁿ & D. Fosterⁿ

author keywords: Camelid; Gastrointestinal agents; Pharmacology; Physiology-gastrointestinal tract

MeSH headings : 2-Pyridinylmethylsulfinylbenzimidazoles / pharmacokinetics; 2-Pyridinylmethylsulfinylbenzimidazoles / therapeutic use; Animals; Anti-Ulcer Agents / pharmacokinetics; Anti-Ulcer Agents / therapeutic use; Camelids, New World; Hydrogen-Ion Concentration; Pantoprazole; Stomach Ulcer / prevention & control; Stomach Ulcer / veterinary

topics (OpenAlex): Helicobacter pylori-related gastroenterology studies; Gastrointestinal motility and disorders; Gastroesophageal reflux and treatments

TL;DR: Based on the results of this study, pantoprazole represents a safe and effective drug for increasing 3rd compartment pH in camelids and either IV or SC administration is likely to be an effective treatment for gastric ulcers. (via Semantic Scholar)

10.1111/j.1939-1676.2010.0508.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: August 6, 2018

2010 article

Pharmacokinetics and tissue depletion of florfenicol in Leghorn and Taiwan Native chickens

CHANG, S. K., DAVIS, J. L., CHENG, C. N., SHIEN, R. H., HSIEH, M. K., KOH, B. W., & CHOU, C. C. (2010, June 10). Journal of Veterinary Pharmacology and Therapeutics.

By: S. Chang^*, J. Davisⁿ, C. Cheng^*, R. Shien^*, M. Hsieh^*, B. Koh^*, C. Chou ^*

MeSH headings : Animals; Anti-Bacterial Agents / pharmacokinetics; Brain / metabolism; Chickens / genetics; Chickens / metabolism; Drug Residues / metabolism; Drug Residues / pharmacokinetics; Intestines / chemistry; Kidney / chemistry; Liver / chemistry; Muscle, Skeletal / metabolism; Myocardium / chemistry; Polysaccharides / chemistry; Spleen / chemistry; Thiamphenicol / analogs & derivatives; Thiamphenicol / chemistry; Thiamphenicol / pharmacokinetics

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Antibiotic Resistance in Bacteria; Bacterial Identification and Susceptibility Testing; Pesticide Residue Analysis and Safety; Cancer therapeutics and mechanisms

TL;DR: Results from this investigation demonstrate the practicality of using in vivo microdialysis in chickens for pharmacokinetic studies and reveal significant time-dependent differences in the free concentrations of Ff in leg and breast muscles. (via Semantic Scholar)

10.1111/j.1365-2885.2009.01155.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2010 journal article

Pharmacokinetics/pharmacodynamics of Quinapril in horses

Journal of Equine Veterinary Science, 30(10), 537–537.

By: J. Davids

Source: NC State University Libraries

Added: August 6, 2018

2010 journal article

The pharmacokinetics and in vitro cyclooxygenase selectivity of deracoxib in horses

Journal of Veterinary Pharmacology and Therapeutics, 34(1), 12–16.

By: J. Davis^*, J. Marshall^*, M. Papichⁿ , A. Blikslager^* & N. Campbellⁿ

Contributors: J. Davis^*, J. Marshall^*, M. Papichⁿ , A. Blikslager^* & N. Campbellⁿ

MeSH headings : Animals; Cyclooxygenase Inhibitors / blood; Cyclooxygenase Inhibitors / pharmacokinetics; Cyclooxygenase Inhibitors / pharmacology; Horses / blood; Horses / metabolism; Sulfonamides / blood; Sulfonamides / pharmacokinetics; Sulfonamides / pharmacology

topics (OpenAlex): Inflammatory mediators and NSAID effects; Estrogen and related hormone effects; Veterinary medicine and infectious diseases

TL;DR: It is shown that deracoxib is absorbed in the horse after oral administration, and may offer a useful alternative for anti-inflammatory treatment of various conditions in the dog and horse. (via Semantic Scholar)

10.1111/j.1365-2885.2010.01185.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries, Crossref, ORCID

Added: August 6, 2018

2009 journal article

Anti-inflammatory effects of intravenously administered lidocaine hydrochloride on ischemia-injured jejunum in horses

American Journal of Veterinary Research, 70(10), 1259–1268.

By: V. Cookⁿ, J. Jones Shultsⁿ, M. McDowellⁿ, N. Campbellⁿ, J. Davisⁿ, J. Marshallⁿ, A. Blikslagerⁿ

Contributors: V. Cookⁿ, J. Shultsⁿ, M. McDowellⁿ, N. Campbellⁿ, J. Davisⁿ, J. Marshallⁿ, A. Blikslagerⁿ

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Clonixin / adverse effects; Clonixin / analogs & derivatives; Female; Gene Expression Regulation, Enzymologic / drug effects; Horse Diseases / chemically induced; Horse Diseases / drug therapy; Horses; Intestinal Diseases / chemically induced; Intestinal Diseases / veterinary; Ischemia / chemically induced; Jejunum / drug effects; Lidocaine / therapeutic use; Male; Prostaglandin-Endoperoxide Synthases / genetics; Prostaglandin-Endoperoxide Synthases / metabolism

topics (OpenAlex): Veterinary Pharmacology and Anesthesia; Veterinary Equine Medical Research; Inflammatory mediators and NSAID effects

TL;DR: In horses with ischemia-injured jejunum, lidocaine administered IV reduced plasma prostaglandin E(2) metabolite concentration and mucosal COX-2 expression and coadministration of lidocane with flunixin ameliorated the flunxin-induced increase in mucosal neutrophil counts. (via Semantic Scholar)

10.2460/ajvr.70.10.1259

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, Crossref, ORCID, NC State University Libraries

Added: August 6, 2018

2009 article

Babesiosis Caused by a Large Babesia Species in 7 Immunocompromised Dogs

Sikorski, L. E., Birkenheuer, A. J., Holowaychuk, M. K., McCleary-Wheeler, A. L., Davis, J. M., & Littman, M. P. (2009, November 30). Journal of Veterinary Internal Medicine, Vol. 24, pp. 127–131.

By: L. Sikorski^*, A. Birkenheuerⁿ , M. Holowaychukⁿ, A. McCleary-Wheelerⁿ, J. Davisⁿ & M. Littman ^*

author keywords: Anemia; Chemotherapy; Splenectomy; Thrombocytopenia

MeSH headings : Animals; Babesia / classification; Babesia / genetics; Babesiosis / parasitology; Babesiosis / veterinary; DNA, Protozoan / genetics; Dog Diseases / immunology; Dog Diseases / parasitology; Dogs; Immunocompromised Host; RNA, Ribosomal, 18S / genetics; Retrospective Studies

topics (OpenAlex): Vector-borne infectious diseases; Vector-Borne Animal Diseases; Viral Infections and Vectors

TL;DR: Dogs with pigmenturia, anemia, and thrombocytopenia should be tested for Babesia sp. (via Semantic Scholar)

10.1111/j.1939-1676.2009.0440.x

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open access via onlinelibrary.wiley.com (publisher PDF)

PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, ORCID, NC State University Libraries

Added: August 6, 2018

2009 article

Effects of compounding and storage conditions on stability of pergolide mesylate

Davis, J. L., Kirk, L. M., Davidson, G. S., & Papich, M. G. (2009, January 31). Journal of the American Veterinary Medical Association, Vol. 234, pp. 385–389.

By: J. Davisⁿ, L. Kirk, G. Davidson^* & M. Papich^*

MeSH headings : Administration, Oral; Animals; Dopamine Agonists / chemistry; Dopamine Agonists / standards; Dopamine Agonists / therapeutic use; Drug Compounding / methods; Drug Compounding / standards; Drug Compounding / veterinary; Drug Stability; Drug Storage / standards; Horse Diseases / drug therapy; Horses; Light; Pergolide / chemistry; Pergolide / standards; Pergolide / therapeutic use; Pharmaceutical Solutions / chemistry; Pharmaceutical Solutions / standards; Pharmaceutical Solutions / therapeutic use; Pituitary ACTH Hypersecretion / drug therapy; Pituitary ACTH Hypersecretion / veterinary; Temperature; Time Factors

topics (OpenAlex): Pain Management and Opioid Use; Anesthesia and Pain Management; Pharmaceutical studies and practices

TL;DR: Results indicated that pergolide mesylate was unstable after compounding in an aqueous vehicle and that storage conditions had an effect on stability of the compounded formulation. (via Semantic Scholar)

10.2460/javma.234.3.385

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

6. Clean Water and Sanitation (OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2009 journal article

Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle

Journal of the American Veterinary Medical Association, 234(2), 245–248.

By: G. Smithⁿ , J. Davis^*, R. Baynes^* , J. Yeatts^*, B. Barlow^* & J. Riviere^*

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / analysis; Anti-Bacterial Agents / pharmacokinetics; Cattle; Chromatography, High Pressure Liquid / methods; Chromatography, High Pressure Liquid / veterinary; Drug Residues / analysis; Female; Infusions, Parenteral / veterinary; Lactation; Mammary Glands, Animal / metabolism; Mastitis, Bovine / drug therapy; Mastitis, Bovine / metabolism; Metabolic Clearance Rate; Milk / chemistry; Prospective Studies; Tylosin / administration & dosage; Tylosin / analogs & derivatives; Tylosin / analysis; Tylosin / pharmacokinetics

topics (OpenAlex): Milk Quality and Mastitis in Dairy Cows; Microbial infections and disease research; Polyamine Metabolism and Applications

TL;DR: Findings indicated that tilmicosin should not be administered by the intramammary route in lactating dairy cows, and milk from all glands of any cows accidentally treated should be discarded for a minimum of 82 days following intramamsary administration. (via Semantic Scholar)

10.2460/javma.234.2.245

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, Crossref

Added: August 6, 2018

2009 personal communication

Supports compounding standards response

By: J. Davis, L. Kirk, G. Davidson & M. Papich

ISBN: 0003-1488

Source: NC State University Libraries

Added: August 6, 2018

2009 article

Third‐compartment cannulation in alpacas using a polyurethane gastrostomy tube

Smith, G. W., Gerard, M. P., Campbell, N. B., Foster, D. M., Smith, S. M., & Davis, J. L. (2009, November 23). Australian Veterinary Journal, Vol. 87, pp. 487–491.

By: G. Smithⁿ , M. Gerardⁿ , N. Campbellⁿ, D. Fosterⁿ , S. Smithⁿ & J. Davisⁿ

author keywords: alpacas; camelids; cannulation; nutritional support; third compartment

MeSH headings : Animals; Camelids, New World / surgery; Gastrostomy / instrumentation; Gastrostomy / methods; Gastrostomy / veterinary; Male; Polyurethanes; Prospective Studies; Surgery, Veterinary / instrumentation; Surgery, Veterinary / methods; Treatment Outcome

topics (OpenAlex): Clinical Nutrition and Gastroenterology; Diet and metabolism studies; Congenital Anomalies and Fetal Surgery

TL;DR: Surgical placement of polyurethane tubes designed for percutaneous endoscopic gastrostomy is a useful method of cannulating the third compartment in camelids and can be used for nutritional support and fluid therapy in sick camelids that might need long-term care. (via Semantic Scholar)

10.1111/j.1751-0813.2009.00510.x

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UN Sustainable Development Goal Categories

2. Zero Hunger (Web of Science; OpenAlex)

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: August 6, 2018

2009 article

Update on drugs prohibited from extralabel use in food animals

Davis, J. L., Smith, G. W., Baynes, R. E., Tell, L. A., Webb, A. I., & Riviere, J. E. (2009, September 1). Journal of the American Veterinary Medical Association, Vol. 235, pp. 528–534.

By: J. Davis^*, G. Smithⁿ , R. Baynesⁿ , L. Tell, A. Webb^* & J. Riviereⁿ

MeSH headings : Animals; Animals, Domestic; Food / standards; Legislation, Drug; Legislation, Veterinary; United States; Veterinary Drugs

topics (OpenAlex): Pharmacological Effects and Assays; Animal Nutrition and Physiology; Viral gastroenteritis research and epidemiology

10.2460/javma.235.5.528

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UN Sustainable Development Goal Categories

2. Zero Hunger (OpenAlex)

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2008 article

Attenuation of ischaemic injury in the equine jejunum by administration of systemic lidocaine

Equine Veterinary Journal, Vol. 40, pp. 353–357.

By: V. Cook, J. Shults, M. McDowell, N. Campbell, J. Davis & A. Blikslager

topics (OpenAlex):

10.2746/04251640SX293574

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Sources: NC State University Libraries, NC State University Libraries

Added: August 6, 2018

2008 article

Comparison of two indirect techniques for local delivery of a high dose of an antimicrobial in the distal portion of forelimbs of horses

Errico, J. A., Trumble, T. N., Bueno, A. C. D., Davis, J. L., & Brown, M. P. (2008, March 1). American Journal of Veterinary Research.

By: J. Errico^*, T. Trumble, A. Bueno^*, J. Davisⁿ & M. Brown^*

MeSH headings : Amikacin / administration & dosage; Amikacin / blood; Amikacin / pharmacokinetics; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Cross-Over Studies; Female; Forelimb / metabolism; Horses / blood; Horses / metabolism; Infusions, Intraosseous / veterinary; Injections, Intravenous / veterinary; Perfusion / veterinary; Synovial Fluid / metabolism; Tourniquets / veterinary

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Veterinary Equine Medical Research; Coccidia and coccidiosis research

TL;DR: Both techniques reliably achieved synovial fluid concentrations of amikacin consistent with concentration-dependent killing for bacteria commonly encountered in horses with septic arthritis. (via Semantic Scholar)

10.2460/ajvr.69.3.334

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: August 6, 2018

2008 article

Exposure to Phenobarbital in a Foal after Nursing a Mare Treated with Phenobarbital

Wong, D. M., Papich, M. G., & Davis, J. L. (2008, January 1). Journal of Veterinary Internal Medicine, Vol. 22, pp. 227–230.

By: D. Wong ^*, M. Papichⁿ & J. Davisⁿ

MeSH headings : Animals; Animals, Newborn / blood; Animals, Suckling; Anticonvulsants / adverse effects; Anticonvulsants / blood; Anticonvulsants / pharmacokinetics; Anticonvulsants / therapeutic use; Female; Horse Diseases / drug therapy; Horses; Milk / chemistry; Phenobarbital / adverse effects; Phenobarbital / blood; Phenobarbital / pharmacokinetics; Phenobarbital / therapeutic use; Pregnancy; Pregnancy Complications / drug therapy; Pregnancy Complications / veterinary; Prenatal Exposure Delayed Effects / veterinary; Seizures / drug therapy; Seizures / veterinary

topics (OpenAlex): Parasitic Infections and Diagnostics; Coccidia and coccidiosis research; Toxoplasma gondii Research Studies

10.1111/j.1939-1676.2007.0036.x

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open access via onlinelibrary.wiley.com (publisher PDF)

PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

14. Life Below Water (OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2008 journal article

FARAD digest - Extralabel use of nonsteroidal anti-inflammatory drugs in cattle

Journal of the American Veterinary Medical Association, 232(5), 697–701.

By: G. Smith , J. Davis, L. Tell, A. Webb & J. Riviere

Source: NC State University Libraries

Added: August 6, 2018

2008 journal article

Ocular distribution and toxicity of intravitreal injection of triamcinolone acetonide in normal equine eyes

Veterinary Ophthalmology, 11, 15–19.

By: N. Yi ⁿ, J. Davisⁿ, J. Salmonⁿ & B. Gilgerⁿ

author keywords: horses; intravitreal; pharmacokinetics; toxicity; triamcinolone acetonide

MeSH headings : Animals; Anti-Inflammatory Agents / pharmacokinetics; Anti-Inflammatory Agents / toxicity; Aqueous Humor / chemistry; Chromatography, High Pressure Liquid / methods; Chromatography, High Pressure Liquid / veterinary; Dose-Response Relationship, Drug; Electroretinography / veterinary; Horses / blood; Horses / metabolism; Injections / adverse effects; Injections / veterinary; Retina / drug effects; Tissue Distribution; Triamcinolone Acetonide / pharmacokinetics; Triamcinolone Acetonide / toxicity; Vitreous Body / chemistry

topics (OpenAlex): Ocular Infections and Treatments; Diphtheria, Corynebacterium, and Tetanus; Retinal Diseases and Treatments

TL;DR: There was no evidence of overt toxicity from intravitreal TA in normal horses and a single intravItreal injection resulted in TA ocular levels for 21 days, however, the risk for bacterial infections with intrav itreal injection or anterior chamber aspirations in horses is high. (via Semantic Scholar)

10.1111/j.1463-5224.2008.00636.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2008 journal article

Ocular toxicity and distribution of subconjunctival and intravitreal rapamycin in horses

Journal of Veterinary Pharmacology and Therapeutics, 31(6), 511–516.

By: L. Douglasⁿ, N. Yiⁿ, J. Davisⁿ, J. Salmonⁿ & B. Gilgerⁿ

MeSH headings : Animals; Anti-Bacterial Agents / adverse effects; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / therapeutic use; Chromatography, High Pressure Liquid; Dermatitis, Phototoxic; Horses; Sirolimus / adverse effects; Sirolimus / pharmacokinetics; Sirolimus / therapeutic use; Tissue Distribution; Uveitis / drug therapy; Uveitis / veterinary

topics (OpenAlex): Ocular Infections and Treatments; Intraocular Surgery and Lenses; Antibiotics Pharmacokinetics and Efficacy

TL;DR: Drug could be detected in both the aqueous and vitreous humor after intravitreal injection and no evidence of ocular toxicity was noted on ophthalmic examination or histopathology, suggesting a lack of RAPA phototoxicity. (via Semantic Scholar)

10.1111/j.1365-2885.2008.00986.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

6. Clean Water and Sanitation (OpenAlex)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2008 journal article

Pharmacokinetics of voriconazole after oral administration of single and multiple doses in African grey parrots (Psittacus erithacus timneh)

American Journal of Veterinary Research, 69(1), 114–121.

By: K. Flammerⁿ, J. Nettifee Osborne^* , D. Webb^*, L. Foster^*, S. Dillard^* & J. Davis^*

MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Drug Administration Schedule; Psittaciformes / metabolism; Pyrimidines / administration & dosage; Pyrimidines / blood; Pyrimidines / pharmacokinetics; Triazoles / administration & dosage; Triazoles / blood; Triazoles / pharmacokinetics; Voriconazole

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Antibiotic Resistance in Bacteria; Antifungal resistance and susceptibility

TL;DR: Oral administration of 12 to 18 mg of voriconazole/kg twice daily is a rational starting dose for treatment of African grey parrots infected with Aspergillus or other fungal organisms that have a minimal inhibitory concentration for vorIconazole < or = 0.4 microg/mL. (via Semantic Scholar)

10.2460/ajvr.69.1.114

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

6. Clean Water and Sanitation (OpenAlex)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2008 journal article

The use of antifungals

Veterinary Technician, 29(7), 428-.

By: J. Davis

Source: NC State University Libraries

Added: August 6, 2018

2007 journal article

Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum

American Journal of Veterinary Research, 68(6), 614–624.

By: D. Littleⁿ, S. Brown, N. Campbell^*, A. Moeser^*, J. Davis^* & A. Blikslager^*

Contributors: D. Littleⁿ, S. Brown, N. Campbell^*, A. Moeser^*, J. Davis^* & A. Blikslager^*

MeSH headings : Animals; Clonixin / analogs & derivatives; Clonixin / pharmacokinetics; Clonixin / therapeutic use; Cyclooxygenase Inhibitors / pharmacokinetics; Cyclooxygenase Inhibitors / therapeutic use; Horse Diseases / drug therapy; Horses; Intestinal Diseases / drug therapy; Intestinal Diseases / veterinary; Ischemia / veterinary; Jejunum / injuries; Meloxicam; Thiazines / pharmacokinetics; Thiazines / therapeutic use; Thiazoles / pharmacokinetics; Thiazoles / therapeutic use

topics (OpenAlex): Veterinary Equine Medical Research; Inflammatory mediators and NSAID effects; Veterinary Pharmacology and Anesthesia

TL;DR: It is suggested that IV administration of meloxicam may be a useful alternative to flunixin meglumine for postoperative treatment of horses with colic. (via Semantic Scholar)

10.2460/ajvr.68.6.614

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, Crossref, ORCID, NC State University Libraries

Added: August 6, 2018

2007 article

Gabapentin for the treatment of neuropathic pain in a pregnant horse

Davis, J. L., Posner, L. P., & Elce, Y. (2007, September 1). Journal of the American Veterinary Medical Association.

By: J. Davisⁿ, L. Posner^* & Y. Elce^*

MeSH headings : Amines / adverse effects; Amines / therapeutic use; Analgesics / adverse effects; Analgesics / therapeutic use; Animals; Colic / surgery; Colic / veterinary; Cyclohexanecarboxylic Acids / adverse effects; Cyclohexanecarboxylic Acids / therapeutic use; Female; Gabapentin; Horses; Neuralgia / drug therapy; Neuralgia / etiology; Neuralgia / veterinary; Pain Measurement; Postoperative Complications / drug therapy; Postoperative Complications / veterinary; Pregnancy; Safety; Treatment Outcome; gamma-Aminobutyric Acid / adverse effects; gamma-Aminobutyric Acid / therapeutic use

topics (OpenAlex): Veterinary Equine Medical Research; Plant Toxicity and Pharmacological Properties; Pain Mechanisms and Treatments

TL;DR: Gabapentin appeared to be a safe, effective, and economical treatment for neuropathic pain in this horse. (via Semantic Scholar)

10.2460/javma.231.5.755

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2007 article

Nonsecretory multiple myeloma in a horse

Morton, A. J., Davi, J. L., Redding, W. R., & Jones, S. L. (2007, November 29). Equine Veterinary Education, Vol. 19, pp. 564–568.

By: A. Morton^*, J. Daviⁿ, W. Reddingⁿ & S. Jonesⁿ

author keywords: horse; myeloma; nuclear scintigraphy; lameness; neoplasia

topics (OpenAlex): Veterinary Equine Medical Research; Coccidia and coccidiosis research; Helminth infection and control

10.2746/095777307X217852

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2007 article

Pharmacokinetics and tissue distribution of enrofloxacin and its active metabolite ciprofloxacin in calves

DAVIS, J. L., FOSTER, D. M., & PAPICH, M. G. (2007, October 24). Journal of Veterinary Pharmacology and Therapeutics, Vol. 30, pp. 564–571.

By: J. Davisⁿ, D. Foster^* & M. Papichⁿ

MeSH headings : Animals; Animals, Newborn / metabolism; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacology; Area Under Curve; Cattle / metabolism; Ciprofloxacin / administration & dosage; Ciprofloxacin / blood; Ciprofloxacin / pharmacology; Enrofloxacin; Fluoroquinolones / administration & dosage; Fluoroquinolones / blood; Fluoroquinolones / pharmacology; Injections, Subcutaneous / veterinary; Tissue Distribution

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Bacterial Identification and Susceptibility Testing; Streptococcal Infections and Treatments

TL;DR: It is concluded that Cmax/MIC and AUC/MIC ratios for free drug concentrations in plasma and ISF would meet suggested ratios for a targeted MIC of 0.06 microg/mL. (via Semantic Scholar)

10.1111/j.1365-2885.2007.00914.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: August 6, 2018

2007 journal article

Pharmacokinetics of etodolac in the horse following oral and intravenous administration

Journal of Veterinary Pharmacology and Therapeutics, 30(1), 43–48.

By: J. Davisⁿ, M. Papichⁿ , A. Morton ^*, J. Gayle^*, A. Blikslager^* & N. Campbellⁿ

Contributors: J. Davisⁿ, M. Papichⁿ , A. Morton ^*, J. Gayle^*, A. Blikslager^* & N. Campbellⁿ

MeSH headings : Administration, Oral; Animals; Area Under Curve; Cross-Over Studies; Cyclooxygenase 1 / drug effects; Cyclooxygenase 2 / drug effects; Cyclooxygenase Inhibitors / administration & dosage; Cyclooxygenase Inhibitors / blood; Cyclooxygenase Inhibitors / pharmacokinetics; Cyclooxygenase Inhibitors / pharmacology; Etodolac / administration & dosage; Etodolac / blood; Etodolac / pharmacokinetics; Etodolac / pharmacology; Female; Horses / metabolism; Injections, Intravenous / veterinary; Male

topics (OpenAlex): Inflammatory mediators and NSAID effects; Analytical Methods in Pharmaceuticals; Pharmacological Effects and Assays

TL;DR: It was showed that etodolac is well absorbed in the horse after oral administration, and may offer a useful alternative for anti-inflammatory treatment of various conditions in thehorse. (via Semantic Scholar)

10.1111/j.1365-2885.2007.00811.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries, Crossref, ORCID

Added: August 6, 2018

2006 journal article

Evaluation of concentration of voriconazole in aqueous humor after topical and oral administration in horses

American Journal of Veterinary Research, 67(2), 296–301.

By: A. Clodeⁿ, J. Davis^*, J. Salmon^*, T. Michau^* & B. Gilger^*

MeSH headings : Administration, Oral; Administration, Topical; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / adverse effects; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Aqueous Humor / chemistry; Dose-Response Relationship, Drug; Female; Horses / metabolism; Male; Pyrimidines / administration & dosage; Pyrimidines / adverse effects; Pyrimidines / blood; Pyrimidines / pharmacokinetics; Triazoles / administration & dosage; Triazoles / adverse effects; Triazoles / blood; Triazoles / pharmacokinetics; Voriconazole

topics (OpenAlex): Ocular Infections and Treatments; Antifungal resistance and susceptibility; Intraocular Surgery and Lenses

10.2460/ajvr.67.2.296

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, Crossref, NC State University Libraries

Added: August 6, 2018

2006 journal article

Mucosal permeability of water-soluble drugs in the equine jejunum: a preliminary investigation

Journal of Veterinary Pharmacology and Therapeutics, 29(5), 379–385.

By: J. Davisⁿ, D. Littleⁿ, A. Blikslagerⁿ & M. Papich^*

Contributors: J. Davisⁿ, D. Littleⁿ, A. Blikslagerⁿ & M. Papich^*

MeSH headings : Animals; Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacokinetics; Anti-Infective Agents / pharmacology; Biological Availability; Cephalexin / chemistry; Cephalexin / pharmacokinetics; Fluconazole / chemistry; Fluconazole / pharmacokinetics; Fluoroquinolones / chemistry; Fluoroquinolones / pharmacokinetics; Horses; Intestinal Mucosa / drug effects; Jejunum / metabolism; Linear Models; Metronidazole / chemistry; Metronidazole / pharmacokinetics; Permeability / drug effects; Quinolones / chemistry; Quinolones / pharmacokinetics; Solubility

topics (OpenAlex): Drug Transport and Resistance Mechanisms; Drug Solubulity and Delivery Systems; Advanced Drug Delivery Systems

TL;DR: The Ussing chamber is a promising method for determining mucosal permeability in the horse and the low permeability of cephalexin across the tissue may indicate a lack of active transporters that are found in other species. (via Semantic Scholar)

10.1111/j.1365-2885.2006.00757.x

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, Crossref, ORCID

Added: August 6, 2018

2006 article

Pharmacokinetics and tissue distribution of doxycycline after oral administration of single and multiple doses in horses

Davis, J. L., Salmon, J. H., & Papich, M. G. (2006, February 1). American Journal of Veterinary Research, Vol. 67, pp. 310–316.

By: J. Davisⁿ, J. Salmon^* & M. Papich^*

MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Doxycycline / administration & dosage; Doxycycline / blood; Doxycycline / pharmacokinetics; Drug Administration Schedule; Female; Food Deprivation; Half-Life; Horses / metabolism; Male; Tissue Distribution

topics (OpenAlex): Veterinary medicine and infectious diseases; Antibiotics Pharmacokinetics and Efficacy; Veterinary Equine Medical Research

TL;DR: Results suggest that doxycycline administered at a dosage of 20 mg/kg, PO, every 24 hours will result in drug concentrations adequate for killing intracellular bacteria and bacteria with minimum inhibitory concentration < or = 0.25 microg/mL. (via Semantic Scholar)

10.2460/ajvr.67.2.310

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2006 article

Pharmacokinetics of voriconazole after oral and intravenous administration to horses

Davis, J. L., Salmon, J. H., & Papich, M. G. (2006, June 1). American Journal of Veterinary Research, Vol. 67, pp. 1070–1075.

By: J. Davisⁿ, J. Salmon^* & M. Papich^*

MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Stability; Female; Horses / blood; Injections, Intravenous; Male; Pyrimidines / administration & dosage; Pyrimidines / blood; Pyrimidines / pharmacokinetics; Triazoles / administration & dosage; Triazoles / blood; Triazoles / pharmacokinetics; Voriconazole

topics (OpenAlex): Antifungal resistance and susceptibility; Ocular Infections and Treatments; Antibiotics Pharmacokinetics and Efficacy

TL;DR: It was concluded that administration of voriconazole at a dosage of 4 mg/kg, PO, every 24 hours will attain plasma concentrations adequate for treatment of horses with fungal infections for which the fungi have a minimum inhibitory concentration. (via Semantic Scholar)

10.2460/ajvr.67.6.1070

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2006 article

The pharmacokinetics of orbifloxacin in the horse following oral and intravenous administration

DAVIS, J. L., PAPICH, M. G., & WEINGARTEN, A. (2006, April 27). Journal of Veterinary Pharmacology and Therapeutics, Vol. 29, pp. 191–197.

By: J. Davisⁿ, M. Papichⁿ & A. Weingarten^*

MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Ciprofloxacin / administration & dosage; Ciprofloxacin / analogs & derivatives; Ciprofloxacin / blood; Ciprofloxacin / pharmacokinetics; Cross-Over Studies; Drug Administration Schedule; Female; Horses / metabolism; Infusions, Intravenous / veterinary; Male; Protein Binding

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Bacterial Identification and Susceptibility Testing; Antibiotic Resistance in Bacteria

TL;DR: This dose is suggested for further studies on the clinical efficacy of orbifloxacin for treatment of susceptible bacterial infections in the horse, an oral dose of approximately 5 mg/kg once daily will produce plasma concentrations within the suggested range. (via Semantic Scholar)

10.1111/j.1365-2885.2006.00737.x

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2005 article

Pharmacokinetics and tissue distribution of itraconazole after oral and intravenous administration to horses

Davis, J. L., Salmon, J. H., & Papich, M. G. (2005, October 1). American Journal of Veterinary Research, Vol. 66, pp. 1694–1701.

By: J. Davisⁿ, J. Salmonⁿ & M. Papichⁿ

MeSH headings : Administration, Oral; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / pharmacokinetics; Chromatography, High Pressure Liquid / veterinary; Horses / metabolism; Injections, Intravenous / veterinary; Itraconazole / administration & dosage; Itraconazole / blood; Itraconazole / pharmacokinetics; Protein Binding

topics (OpenAlex): Antifungal resistance and susceptibility; Helminth infection and control; Infectious Diseases and Mycology

TL;DR: Itraconazole administered orally as a solution had higher, more consistent absorption than orally administered capsules and attained plasma concentrations that are inhibitory against fungi that infect horses. (via Semantic Scholar)

10.2460/ajvr.2005.66.1694

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2005 article

Pharmacokinetics of oral omeprazole in llamas

POULSEN, K. P., SMITH, G. W., DAVIS, J. L., & PAPICH, M. G. (2005, November 15). Journal of Veterinary Pharmacology and Therapeutics, Vol. 28, pp. 539–543.

By: K. Poulsen, G. Smith^* , J. Davisⁿ & M. Papichⁿ

MeSH headings : Administration, Oral; Animals; Anti-Ulcer Agents / administration & dosage; Anti-Ulcer Agents / blood; Anti-Ulcer Agents / pharmacokinetics; Area Under Curve; Camelids, New World / metabolism; Female; Omeprazole / administration & dosage; Omeprazole / blood; Omeprazole / pharmacokinetics

topics (OpenAlex): Veterinary Equine Medical Research; Antibiotics Pharmacokinetics and Efficacy; Plant Toxicity and Pharmacological Properties

TL;DR: Oral omeprazole produced plasma drug concentrations which are not likely to be associated with clinical efficacy in camelids, and due to low absorption the oral dose was increased to 8 and 12 mg/kg and studies were repeated. (via Semantic Scholar)

10.1111/j.1365-2885.2005.00696.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2004 article

Moxifloxacin pharmacokinetics in horses and disposition into phagocytes after oral dosing

Gardner, S. Y., Davis, J. L., Jones, S. L., LaFevers, D. H., Hoskins, M. S., Mcarver, E. M., & Papich, M. G. (2004, February 1). Journal of Veterinary Pharmacology and Therapeutics, Vol. 27, pp. 57–60.

By: S. Gardnerⁿ, J. Davis^*, S. Jones^* , D. LaFevers^*, M. Hoskins^*, E. Mcarver^*, M. Papichⁿ

MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Aza Compounds / administration & dosage; Aza Compounds / blood; Aza Compounds / pharmacokinetics; Female; Fluoroquinolones; Horses / metabolism; Moxifloxacin; Phagocytes / metabolism; Quinolines / administration & dosage; Quinolines / blood; Quinolines / pharmacokinetics

topics (OpenAlex): Antibiotics Pharmacokinetics and Efficacy; Drug Transport and Resistance Mechanisms; Pneumonia and Respiratory Infections

10.1046/j.0140-7783.2003.00529.x

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PubMed

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: August 6, 2018

2004 journal article

Novel approaches to ocular drug delivery

Current Opinion in Molecular Therapeutics, 6(2), 195–205.

By: J. Davis, B. Gilger & M. Robinson

Source: NC State University Libraries

Added: August 6, 2018

2004 journal article

Quality of heart failure care in managed Medicare and Medicaid patients in North Carolina

The American Journal of Cardiology, 93(6), 714–718.

By: A. Bertoni ^*, V. Duren-Winfield ^*, W. Ambrosius ^*, J. McArdle, C. Sueta, M. Massing, S. Peacock, J. Davis^*, J. Croft ^*, D. Goff ^*

MeSH headings : Adrenergic beta-Antagonists / therapeutic use; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors / therapeutic use; Female; Guideline Adherence; Heart Failure / drug therapy; Heart Failure / epidemiology; Heart Failure / etiology; Humans; Male; Managed Care Programs / standards; Medicaid / standards; Medical Records; Medicare / standards; Middle Aged; North Carolina / epidemiology; Quality Assurance, Health Care; Retrospective Studies; Total Quality Management

topics (OpenAlex): Heart Failure Treatment and Management; Healthcare Policy and Management; Pharmaceutical Practices and Patient Outcomes

TL;DR: Ventricular function assessment and ACE inhibitor prescription rates are higher than beta-blocker prescription rates among Medicare and Medicaid managed care patients in North Carolina. (via Semantic Scholar)

10.1016/j.amjcard.2003.11.053

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Source: Crossref

Added: January 2, 2021

2003 article

A Retrospective Analysis of Hepatic Injury in Horses with Proximal Enteritis (1984–2002)

Davis, J. L., Blikslager, A. T., Catto, K., & Jones, S. L. (2003, January 1). Journal of Veterinary Internal Medicine, Vol. 17, pp. 896–901.

By: J. Davis^*, A. Blikslager^* , K. Catto^* & S. Jones^*

author keywords: colic; duodenitis-proximal jejunitis; equine; gastric reflux; hepatopathy

topics (OpenAlex): Veterinary Equine Medical Research; Veterinary medicine and infectious diseases; Animal health and immunology

10.1892/0891-6640(2003)017<0896:ARAOHI>2.3.CO;2

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2003 journal article

Equine primary immunodeficiencies

Compendium on Continuing Education for the Practicing Veterinarian, 25(7), 548–556.

By: J. Davis & S. Jones

Source: NC State University Libraries

Added: August 6, 2018

2003 article

Suppurative Cholangiohepatitis and Enteritis in Adult Horses

Davis, J. L., & Jones, S. L. (2003, January 1). Journal of Veterinary Internal Medicine, Vol. 17, pp. 583–587.

By: J. Davisⁿ & S. Jonesⁿ

topics (OpenAlex): Gallbladder and Bile Duct Disorders; Veterinary medicine and infectious diseases; Biliary and Gastrointestinal Fistulas

10.1892/0891-6640(2003)017<0583:SCAEIA>2.3.CO;2

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open access via onlinelibrary.wiley.com (publisher PDF)

UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

14. Life Below Water (OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2003 article

The effect of topical administration of atropine sulfate on the normal equine pupil: influence of age, breed and gender

Davis, J. L., Stewart, T., Brazik, E., & Gilger, B. C. (2003, December 1). Veterinary Ophthalmology, Vol. 6, pp. 329–332.

By: J. Davisⁿ, T. Stewart^*, E. Brazikⁿ & B. Gilgerⁿ

author keywords: atropine; equine; mydriasis

MeSH headings : Administration, Topical; Animals; Atropine / administration & dosage; Atropine / pharmacology; Female; Horses / physiology; Male; Mydriatics / administration & dosage; Mydriatics / pharmacology; Ophthalmic Solutions; Pedigree; Pupil / drug effects; Pupil / physiology

topics (OpenAlex): Plant Toxicity and Pharmacological Properties; Phytochemistry and Biological Activities; Veterinary Equine Medical Research

TL;DR: Horses of the Arabian breed and female horses may be more sensitive to effects of cholinergic blockade in the eye following a single dose of 1% atropine sulfate ophthalmic solution in the normal equine eye. (via Semantic Scholar)

10.1111/j.1463-5224.2003.00315.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2003 article

Treatment of peritonitis

Davis, J. L. (2003, December 1). Veterinary Clinics of North America Equine Practice.

By: J. Davisⁿ

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Anti-Inflammatory Agents / therapeutic use; Drainage / veterinary; Endotoxemia / etiology; Endotoxemia / therapy; Endotoxemia / veterinary; Fluid Therapy / veterinary; Horse Diseases / diagnosis; Horse Diseases / etiology; Horse Diseases / therapy; Horses; Peritonitis / etiology; Peritonitis / therapy; Peritonitis / veterinary; Prognosis; Therapeutic Irrigation / veterinary

topics (OpenAlex): Veterinary Equine Medical Research; Venous Thromboembolism Diagnosis and Management; Anesthesia and Pain Management

TL;DR: In summary, peritonitis in the horse is a potentially life-threatening disease that must be treated promptly and aggressively and the prognosis is best determined by an early and quick response to aggressive treatment. (via Semantic Scholar)

10.1016/j.cveq.2003.08.007

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Source: Web Of Science

Added: August 6, 2018

2002 article

Congestive heart failure in horses: 14 cases (1984–2001)

Davis, J. L., Gardner, S. Y., Schwabenton, B., & Breuhaus, B. A. (2002, May 15). Journal of the American Veterinary Medical Association, Vol. 220, pp. 1512–1515.

By: J. Davis^*, S. Gardnerⁿ, B. Schwabentonⁿ & B. Breuhausⁿ

MeSH headings : Animals; Echocardiography / veterinary; Female; Heart Failure / diagnosis; Heart Failure / mortality; Heart Failure / therapy; Heart Failure / veterinary; Horse Diseases / diagnosis; Horse Diseases / mortality; Horse Diseases / therapy; Horses; Male; Prognosis; Retrospective Studies; Tachycardia / diagnosis; Tachycardia / therapy; Tachycardia / veterinary; Treatment Outcome

topics (OpenAlex): Veterinary Equine Medical Research; Cardiac Valve Diseases and Treatments; Cardiac Ischemia and Reperfusion

TL;DR: It is suggested that congestive heart failure is rare in horses and echocardiography was useful in determining the underlying cause in affected horses. (via Semantic Scholar)

10.2460/javma.2002.220.1512

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science; OpenAlex)

Sources: Web Of Science, NC State University Libraries

Added: August 6, 2018

2002 article

Nasal adenocarcinoma with diffuse metastases involving the orbit, cerebrum, and multiple cranial nerves in a horse

Davis, J. L., Gilger, B. C., Spaulding, K., Robertson, I. D., & Jones, S. L. (2002, November 15). Journal of the American Veterinary Medical Association, Vol. 221, pp. 1460–1463.

By: J. Davisⁿ, B. Gilger^* , K. Spaulding^*, I. Robertson^* & S. Jones^*

MeSH headings : Adenocarcinoma / diagnosis; Adenocarcinoma / secondary; Adenocarcinoma / veterinary; Animals; Brain Neoplasms / diagnosis; Brain Neoplasms / secondary; Brain Neoplasms / veterinary; Cerebrospinal Fluid / chemistry; Cranial Nerve Neoplasms / diagnosis; Cranial Nerve Neoplasms / secondary; Cranial Nerve Neoplasms / veterinary; Diagnosis, Differential; Fatal Outcome; Horse Diseases / diagnosis; Horse Diseases / pathology; Horses; Male; Nose Neoplasms / diagnosis; Nose Neoplasms / pathology; Nose Neoplasms / veterinary; Orbital Neoplasms / diagnosis; Orbital Neoplasms / secondary; Orbital Neoplasms / veterinary; Prognosis; Tomography, X-Ray Computed / veterinary

topics (OpenAlex): Veterinary Oncology Research; Infectious Diseases and Mycology; Salivary Gland Tumors Diagnosis and Treatment

TL;DR: A 9-year-old Trakehner gelding examined because of right exophthalmus found a lack of menace response in the right eye, reduced direct and consensual right pupillary light reflexes, ventrolateral strabismus of the rightEye, mild right-sided facial asymmetry, a head tilt to the left, and increased extensor tone in theright limbs. (via Semantic Scholar)

10.2460/javma.2002.221.1460

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, ORCID, NC State University Libraries

Added: August 6, 2018

2002 article

Pharmacokinetics of azithromycin in foals after i.v. and oral dose and disposition into phagocytes

DAVIS, J. L., GARDNER, S. Y., JONES, S. L., SCHWABENTON, B. A., & PAPICH, M. G. (2002, April 1). Journal of Veterinary Pharmacology and Therapeutics, Vol. 25, pp. 99–104.

By: J. Davisⁿ, S. Gardnerⁿ, S. Jonesⁿ , B. Schwabentonⁿ & M. Papichⁿ

MeSH headings : Actinomycetales Infections / drug therapy; Actinomycetales Infections / veterinary; Administration, Oral; Animals; Animals, Newborn; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / therapeutic use; Area Under Curve; Azithromycin / administration & dosage; Azithromycin / blood; Azithromycin / pharmacokinetics; Azithromycin / therapeutic use; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid / veterinary; Female; Horse Diseases / drug therapy; Horses / metabolism; Infusions, Intravenous / veterinary; Macrophages, Alveolar / metabolism; Male; Phagocytes / metabolism; Rhodococcus equi

topics (OpenAlex): Infectious Disease Case Reports and Treatments; Biliary and Gastrointestinal Fistulas; Infections and bacterial resistance

TL;DR: The properties of azithromycin suggest that it may be an alternative to erythromycin for treatment of Rhodococcus equi pneumonia in foals and its disposition in plasma, polymorphonuclear leukocytes (PMN), and alveolar cells was examined to investigate this possibility. (via Semantic Scholar)

10.1046/j.1365-2885.2002.00387.x

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UN Sustainable Development Goal Categories

3. Good Health and Well-being (Web of Science)

Sources: Web Of Science, NC State University Libraries, ORCID

Added: August 6, 2018

2001 article

Acute and chronic mineral oil pneumonitis in two horses

Davis, J. L., Ramirez, S., Campbell, N., & Jones, S. L. (2001, October 1). Equine Veterinary Education, Vol. 13, pp. 230–234.

By: J. Davisⁿ, S. Ramirezⁿ, N. Campbellⁿ & S. Jonesⁿ

topics (OpenAlex): Poisoning and overdose treatments; Veterinary Equine Medical Research

10.1111/j.2042-3292.2001.tb00099.x

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Sources: NC State University Libraries, NC State University Libraries

Added: August 6, 2018

review

Health concerns and management of select veterinary drug residues

Baynes, R. E., Dedonder, K., Kissell, L., Mzyk, D., Marmulak, T., Smith, G., … Riviere, J. E. [Review of ]. Food and Chemical Toxicology, 88, 112–122.

By: R. Baynes , K. Dedonder, L. Kissell, D. Mzyk , T. Marmulak, G. Smith , L. Tell, R. Gehring, J. Davis, J. Riviere

Source: NC State University Libraries

Added: August 6, 2018

Works (95) 19 open access

Works (95)