James Lichty

College of Engineering

Works (3)

Updated: January 28th, 2026 09:32

2025 article

Amyloid β induces hormetic-like effects through major stress pathways in a C. elegans model of Alzheimer’s Disease

Lichty, J. D., Mane, H., Yarmey, V. R., & Miguel, A. S. (2025, April 24). (N. Tavernarakis, Ed.). PLoS ONE.

By: J. Lichty n, H. Mane n, V. Yarmey n & A. Miguel n 

Ed(s): N. Tavernarakis

MeSH headings : Caenorhabditis elegans / metabolism; Caenorhabditis elegans / genetics; Animals; Amyloid beta-Peptides / metabolism; Amyloid beta-Peptides / genetics; Alzheimer Disease / metabolism; Alzheimer Disease / genetics; Alzheimer Disease / pathology; Disease Models, Animal; Humans; Oxidative Stress; Stress, Physiological; Caenorhabditis elegans Proteins / metabolism; Caenorhabditis elegans Proteins / genetics; Hormesis; Signal Transduction; Neurons / metabolism; Heat-Shock Proteins / metabolism; Heat-Shock Proteins / genetics; Neuropeptides / metabolism
topics (OpenAlex): Genetics, Aging, and Longevity in Model Organisms; Circadian rhythm and melatonin; Tryptophan and brain disorders
Sources: Web Of Science, ORCID
Added: April 24, 2025

2025 article

Metagenomic Screening of Globally Sourced Samples for Thermo-, Halo-, and pH-tolerant Carbonic Anhydrases

Lichty, J., & Crook, N. (2025, January 1). SSRN Electronic Journal, Vol. 1.

By: J. Lichty n & N. Crook n 

topics (OpenAlex): Enzyme function and inhibition
Sources: NC State University Libraries, NC State University Libraries
Added: January 27, 2026

2022 article

Identifying C. elegans lifespan mutants by screening for early-onset protein aggregation

Midkiff, D. F., Huayta, J., Lichty, J. D., Crapster, J. P., & San-Miguel, A. (2022, October 28). IScience, Vol. 25, p. 105460.

By: D. Midkiff n, J. Huayta  n, J. Lichty n, J. Crapster n & A. San-Miguel n 

topics (OpenAlex): Genetics, Aging, and Longevity in Model Organisms
TL;DR: It is demonstrated that lifespan mutants can be identified by screening for accelerated protein aggregation through quantitative analysis of fluorescently-labeled aggregates in populations that do not require conditional sterilization or manual separation of parental and progeny populations. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 3, 2023

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