James Otvos

Rashid, S., Sniderman, A., Melone, M., Brown, P. E., Otvos, J. D., Mente, A., … Yusuf, S. (2015). Elevated cholesteryl ester transfer protein (CETP) activity, a major determinant of the atherogenic dyslipidemia, and atherosclerotic cardiovascular disease in South Asians. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 22(4), 468–477. https://doi.org/10.1177/2047487314528461

Ruano, G., Seip, R. L., Windemuth, A., Zollner, S., Tsongalis, G. J., Ordovas, J., … Thompson, P. D. (2006). Apolipoprotein A1 genotype affects the change in high density lipoprotein cholesterol subfractions with exercise training. ATHEROSCLEROSIS, 185(1), 65–69. https://doi.org/10.1016/j.atherosclerosis.2005.05.029

Nuclear magnetic resonance-determined lipoprotein subclass profile in the DCCT/EDIC cohort: associations with carotid intima-media thickness. (2006). Diabetic Medicine: A Journal of the British Diabetic Association, 23(9), 955–966.

Seip, R. L., Otvos, J., Bilbie, C., Tsongalis, G. J., Miles, M., Zoeller, R., … Thompson, P. D. (2006). The effect of apolipoprotein E genotype on serum lipoprotein particle response to exercise. ATHEROSCLEROSIS, 188(1), 126–133. https://doi.org/10.1016/j.atherosclerosis.2005.06.050

Kuivenhoven, J. A., Hovingh, G. K., Tol, A., Jauhiainen, M., Ehnholm, C., Fruchart, J. C., … Kastelein, J. J. P. (2003). Heterozygosity for ABCA1 gene mutations: effects on enzymes, apolipoproteins and lipoprotein particle size. ATHEROSCLEROSIS, 171(2), 311–319. https://doi.org/10.1016/j.atherosclerosis.2003.08.014

Jenkins, A. J., Lyons, T. J., Zheng, D. Y., Otvos, J. D., Lackland, D. T., McGee, D., … Klein, R. L. (2003). Lipoproteins in the DCCT/EDIC cohort: Associations with diabetic nephropathy. KIDNEY INTERNATIONAL, 64(3), 817–828. https://doi.org/10.1046/j.1523-1755.2003.00164.x

Otvos, J., Jeyarajah, E., & Shalaurova, I. (2003). Method of determining presence and concentration of lipoprotein X in blood plasma and serum. Washington, DC: U.S. Patent and Trademark Office.

Otvos, J. D., & Bennett, D. W. (2003). Methods and computer program products for determining risk of developing type 2 diabetes and other insulin resistance related disorders. Washington, DC: U.S. Patent and Trademark Office.

Otvos, J. (2003). Methods for providing personalized lipoprotein-based risk assessments. Washington, DC: U.S. Patent and Trademark Office.

Otvos, J. (2003). Methods, systems, and computer program products for analyzing and presenting NMR lipoprotein-based risk assessment results. Washington, DC: U.S. Patent and Trademark Office.

Jenkins, A. J., Lyons, T., Zheng, D. Y., Otvos, J. D., Lackland, D. T., McGee, D., … Klein, R. L. (2003). Serum lipoproteins in the diabetes control and complications trial/epidemiology of diabetes intervention and complications cohort - Associations with gender and glycemia. DIABETES CARE, 26(3), 810–818. https://doi.org/10.2337/diacare.26.3.810

Brousseau, M. E., JJ O'Connor, Ordovas, J. M., Collins, D., Otvos, J. D., Massov, T., … Schaefer, E. J. (2002, July). Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency - Veterans Affairs HDL Cholesterol Intervention Trial. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, Vol. 22, pp. 1148–1154. https://doi.org/10.1161/01.ATV.0000024566.57589.2E

Otvos, J. D., Shalaurova, I., Freedman, D. S., & Rosenson, R. S. (2002). Effects of pravastatin treatment on lipoprotein subclass profiles and particle size in the PLAC-I trial. ATHEROSCLEROSIS, 160(1), 41–48. https://doi.org/10.1016/S0021-9150(01)00544-5

Humphries, S. E., Berglund, L., Isasi, C. R., Otvos, J. D., Kaluski, D., Deckelbaum, R., … Talmud, P. (2002). Loci for CETP, LPL, LIPC, and APOC3 affect plasma lipoprotein size and subpopulation distribution in Hispanic and non- Hispanic white subjects: the Columbia University BioMarkers Study. Nutrition, Metabolism, and Cardiovascular Diseases, 12(4), 163–172.

Rosenson, R. S., Otvos, J. D., & Freedman, D. S. (2002). Relations of lipoprotein subclass levels and low-density lipoprotein size to progression of coronary artery disease in the pravastatin limitation of atherosclerosis in the coronary arteries (PLAC-I) trial. AMERICAN JOURNAL OF CARDIOLOGY, 90(2), 89–94. https://doi.org/10.1016/S0002-9149(02)02427-X

Galluzzi, JR, Cupples, L. A., Otvos, J. D., Wilson, P. W. F., Schaefer, E. J., & Ordovas, J. M. (2001). Association of the A/T54 polymorphism in the intestinal fatty acid binding protein with variations in plasma lipids in The Framingham Offspring Study. ATHEROSCLEROSIS, 159(2), 417–424. https://doi.org/10.1016/S0021-9150(01)00517-2

Russo, G. T., Meigs, J. B., Cupples, L. A., Demissie, S., Otvos, J. D., Wilson, P. W. F., … Ordovas, J. M. (2001). Association of the Sst-I polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: the Framingham offspring study. ATHEROSCLEROSIS, 158(1), 173–181. https://doi.org/10.1016/S0021-9150(01)00409-9

Freedman, D. S., Bowman, B. A., Srinivasan, SR, Berenson, G. S., & Otvos, J. D. (2001). Distribution and correlates of high-density lipoprotein subclasses among children and adolescents. METABOLISM-CLINICAL AND EXPERIMENTAL, 50(3), 370–376. https://doi.org/10.1053/meta.2001.21027

Miller, M., Dolinar, C., Cromwell, W., & Otvos, J. D. (2001). Effectiveness of high doses of Simvastatin as monotherapy in mixed hyperlipidemia. AMERICAN JOURNAL OF CARDIOLOGY, 87(2), 232-+. https://doi.org/10.1016/S0002-9149(00)01327-8

Tangney, C. C., Mosca, L. J., Otvos, J. D., & Rosenson, R. S. (2001). Oral 17 beta-estradiol and medroxyprogesterone acetate therapy in postmenopausal women increases HDL particle size. ATHEROSCLEROSIS, 155(2), 425–430. https://doi.org/10.1016/s0021-9150(00)00577-3

Zangger, K., Shen, G., Oz, G., Otvos, J. D., & Armitage, I. M. (2001). Oxidative dimerization in metallothionein is a result of intermolecular disulphide bonds between cysteines in the alpha- domain. Biochemical Journal (London, England : 1984), 359(2001 Oct 15), 353–360.

Couture, P., Otvos, J. D., Cupples, L. A., Wilson, P. W. F., Schaefer, E. J., & Ordovas, J. M. (2000). Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study. ATHEROSCLEROSIS, 148(2), 337–343. https://doi.org/10.1016/S0021-9150(99)00281-6

Isasi, C. R., Shea, S., Deckelbaum, R. J., Couch, S. C., Starc, T. J., Otvos, J. D., & Berglund, L. (2000). Apolipoprotein epsilon 2 allele is associated with an anti-atherogenic lipoprotein profile in children: The Columbia University BioMarkers Study. PEDIATRICS, 106(3), 568–575. https://doi.org/10.1542/peds.106.3.568

Ordovas, J. M., Cupples, L. A., Corella, D., Otvos, J. D., Osgood, D., Martinez, A., … Schaefer, E. J. (2000). Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk - The Framingham study. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 20(5), 1323–1329. https://doi.org/10.1161/01.ATV.20.5.1323

Couture, P., Otvos, J. D., Cupples, L. A., Lahoz, C., Wilson, P. W. F., Schaefer, E. J., & Ordovas, J. M. (2000). Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles - The Framingham Offspring Study. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 20(3), 815–822. https://doi.org/10.1161/01.ATV.20.3.815

Freedman, D. S., Bowman, B. A., Otvos, J. D., Srinivasan, SR, & Berenson, G. S. (2000). Levels and correlates of LDL and VLDF, particle sizes among children: the Bogalusa heart study. ATHEROSCLEROSIS, 152(2), 441–449. https://doi.org/10.1016/S0021-9150(99)00495-5

Yu, H. H., Ginsburg, G. S., ML O'Toole, Otvos, J. D., Douglas, P. S., & Rifai, N. (1999). Acute changes in serum lipids and lipoprotein subclasses in triathletes as assessed by proton nuclear magnetic resonance spectroscopy. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 19(8), 1945–1949. https://doi.org/10.1161/01.ATV.19.8.1945

Couture, P., Otvos, J. D., Cupples, L. A., Wilson, P. W. F., Schaefer, E. J., & Ordovas, J. M. (1999). Association of the A-204C polymorphism in the cholesterol 7 alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study. Journal of Lipid Research, 40(10), 1883–1889.

Grundy, S. M., Vega, G. L., Otvos, J. D., Rainwater, D. L., & Cohen, J. C. (1999). Hepatic lipase activity influences high density lipoprotein subclass distribution in normotriglyceridemic men: genetic and pharmacological evidence. Journal of Lipid Research, 40(2), 229–234.

Otvos, J. (1999). Measurement of triglyceride-rich lipoproteins by nuclear magnetic resonance spectroscopy. Clinical Cardiology (Los Altos, Calif.), 22(6 Suppl.), II 21–27. https://doi.org/10.1002/clc.4960221405

Zangger, K., Oz, G., Otvos, J. D., & Armitage, I. M. (1999). Three-dimensional solution structure of mouse [Cd-7]-metallothionein-1 by homonuclear and heteronuclear NMR spectroscopy. PROTEIN SCIENCE, 8(12), 2630–2638. https://doi.org/10.1110/ps.8.12.2630

Li, H., & Otvos, J. D. (1998). Biphasic kinetics of Zn2+ removal from Zn metallothionein by nitrilotriacetate are associated with differential reactivity of the two metal clusters. JOURNAL OF INORGANIC BIOCHEMISTRY, 70(3-4), 187–194. https://doi.org/10.1016/S0162-0134(98)10013-2

Vadlamudi, S., Maclean, P., Israel, R. G., Marks, R. H., Hickey, M., Otvos, J., & Barakat, H. (1998). Effects of oral combined hormone replacement therapy on plasma lipids and lipoproteins. METABOLISM-CLINICAL AND EXPERIMENTAL, 47(10), 1222–1226. https://doi.org/10.1016/S0026-0495(98)90327-4

Lilley, S. H., Spivey, J. M., Vadlamudi, S., Otvos, J., Cummings, D. M., & Barakat, H. (1998). Lipid and lipoprotein responses to oral combined hormonereplacement therapy in normolipemic obese women with controlledtype 2 diabetes mellitus. Journal of Clinical Pharmacology, 38(12), 1107–1115.

Giri, S., Thompson, P. D., Taxel, P., Contois, J. H., Otvos, J., Allen, R., … Waters, D. D. (1998). Oral estrogen improves serum lipids, homocysteine and fibrinolysis in elderly men. ATHEROSCLEROSIS, 137(2), 359–366. https://doi.org/10.1016/S0021-9150(98)00022-7

Giri, S., Thompson, P. D., Taxel, P., Contois, J. H., Otvos, J., Allen, R., … Waters, D. D. (1998). Oral estrogen improves serum lipids, homocysteine and fibrinolysis in elderly men (vol. 137, pg. 359, 1998). Atherosclerosis, 138(2), 403.

Freedman, D. S., Otvos, J. D., Jeyarajah, E. J., Barboriak, J. J., Anderson, A. J., & Walker, J. A. (1998). Relation of lipoprotein subclasses as measured by proton nuclear magnetic resonance spectroscopy to coronary artery disease. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 18(7), 1046–1053. https://doi.org/10.1161/01.ATV.18.7.1046

Parsons, S. K., Skapek, S. X., Neufeld, E. J., Kuhlman, C., Young, M. L., Donnelly, M., … Rifai, N. (1997). Asparaginase associated lipid abnormalities in children with acute lymphoblastic leukemia. Blood, 89(6), 1886–1895.

Otvos, J. (1994). Method and apparatus for measuring classes and subclasses of lipoproteins. Washington, DC: U.S. Patent and Trademark Office.