James E. Gibson

Works (2)

Updated: July 5th, 2023 15:49

2011 journal article

Brevetoxin 2 alters expression of apoptotic, DNA damage, and cytokine genes in Jurkat cells

Human & Experimental Toxicology, 30(3), 182–191.

By: R. Murrell & J. Gibson

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Brevetoxins 2, 3, 6, and 9 show variability in potency and cause significant induction of DNA damage and apoptosis in Jurkat E6-1 cells

ARCHIVES OF TOXICOLOGY, 83(11), 1009–1019.

By: R. Murrell n & J. Gibson n

MeSH headings : Apoptosis / drug effects; Caspases / drug effects; Caspases / metabolism; Cell Proliferation / drug effects; Comet Assay; DNA Damage / drug effects; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Jurkat Cells; Marine Toxins / administration & dosage; Marine Toxins / toxicity; Mutagenicity Tests; Mutagens / administration & dosage; Mutagens / toxicity; Oxocins / administration & dosage; Oxocins / toxicity; Time Factors
TL;DR: The conclusions are that brevetoxins affect cell proliferation in a dose-dependent fashion, are genotoxic, and cause cell death through an apoptotic mechanism. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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