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Works (11)
Updated: August 5th, 2024 08:19
2024 article
Immune gene regulation is associated with age and environmental adversity in a nonhuman primate
Watowich, M. M., Costa, C. E., Chiou, K. L., Goldman, E. A., Petersen, R. M., Patterson, S., … Snyder-Mackler, N. (2024, July 20). MOLECULAR ECOLOGY.
author keywords: aging; DNA methylation; environmental adversity; gene expression; gene regulation
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: July 30, 2024
2023 journal article
A global catalog of whole-genome diversity from 233 primate species
SCIENCE, 380(6648), 906–912.
TL;DR:
High coverage whole-genome data from 233 primate species representing 86% of genera and all 16 families was used to create a nuclear DNA phylogeny and to reassess evolutionary divergence times among primate clades.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 7, 2023
2023 article
Best practices for genotype imputation from low-coverage sequencing data in natural populations
Watowich, M. M., Chiou, K. L., Graves, B., Montague, M. J., Brent, L. J. N., Higham, J. P., … Snyder-Mackler, N. (2023, August 21). MOLECULAR ECOLOGY RESOURCES.
author keywords: conservation; genotyping; imputation; next-generation sequencing; population genetics
TL;DR:
It is shown that low-coverage imputed genotypes can reliably calculate genetic relatedness and population structure and endorse accurate and effective genotype imputation from low- coverage sequencing, enabling the cost-effective generation of population-scale genetic datasets necessary for tackling many pressing challenges of wildlife conservation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: September 11, 2023
2023 article
Identification of constrained sequence elements across 239 primate genomes
Kuderna, L. F. K., Ulirsch, J. C., Rashid, S., Ameen, M., Sundaram, L., Hickey, G., … Farh, K. K.-H. (2023, November 29). NATURE.
TL;DR:
A whole-genome alignment of 239 species is constructed, representing nearly half of all extant species in the primate order and highlighting the important role of recent evolution in regulatory sequence elements differentiating primates, including humans, from other placental mammals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 25, 2024
2023 journal article
The landscape of tolerated genetic variation in humans and primates
SCIENCE, 380(6648), 929-+.
MeSH headings : Animals; Humans; Base Sequence; Gene Frequency; Genetic Variation; Primates / genetics; Whole Genome Sequencing
TL;DR:
This resource is used to classify 6% of all possible human protein-altering variants as likely benign and impute the pathogenicity of the remaining 94% of variants with deep learning, achieving state-of-the-art accuracy for diagnosing pathogenic variants in patients with genetic diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 7, 2023
2023 journal article
Yearly variation coupled with social interactions shape the skin microbiome in free-ranging rhesus macaques
MICROBIOLOGY SPECTRUM, 11(5).
author keywords: skin microbiome; rhesus macaques; social behavior; year-to-year environment; Cayo Santiago; primates; microbial diversity; 16S rRNA
TL;DR:
The findings indicate that social dynamics interact with yearly environmental changes to shape the skin microbiota in rhesus macaques, with potential implications for understanding the factors affecting the microbiome in humans, which share many biological and social characteristics with these animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 2, 2024
2022 journal article
Limited microbiome differences in captive and semi-wild primate populations consuming similar diets
FEMS MICROBIOLOGY ECOLOGY, 98(10).
author keywords: captivity; diet; microbiome; primate
MeSH headings : Animals; Diet / veterinary; Gastrointestinal Microbiome; Humans; Macaca mulatta; Microbiota; RNA, Ribosomal, 16S
TL;DR:
Although it was found that location was a significant predictor of gut microbial composition, the magnitude of observed differences was relatively small, suggesting that a shared diet may limit the typical influence of environmental microbial exposure on the gut microbiota.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 17, 2022
2022 journal article
Natural disaster and immunological aging in a nonhuman primate
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(8).
MeSH headings : Age Factors; Aging / immunology; Animals; Cross-Sectional Studies; Cyclonic Storms; Disasters; Macaca / immunology; Natural Disasters / mortality; Risk Factors; Survivors / psychology
TL;DR:
Living through an intense hurricane and its aftermath was associated with expression of key immune genes, dysregulated proteostasis networks, and greater expression of inflammatory immune cell-specific marker genes, suggesting that experiencing an extreme hurricane is associated with alterations in immune cell gene regulation similar to aging, potentially accelerating aspects of the aging process.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
13. Climate Action
(OpenAlex)
Source: Web Of Science
Added: March 28, 2022
2022 journal article
Social connections predict brain structure in a multidimensional free-ranging primate society
SCIENCE ADVANCES, 8(15).
MeSH headings : Animals; Brain / diagnostic imaging; Humans; Macaca mulatta; Social Behavior; Temporal Lobe
TL;DR:
It is demonstrated that the size of specific brain structures varies with the number of direct affiliative social connections and suggested that this relationship may arise during development, and proposed links between social network size, biological success, and the expansion of specificbrain circuits are reinforced.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: Web Of Science
Added: May 10, 2022
2021 journal article
Variation in predicted COVID-19 risk among lemurs and lorises
AMERICAN JOURNAL OF PRIMATOLOGY, 83(6).
MeSH headings : Angiotensin-Converting Enzyme 2 / chemistry; Angiotensin-Converting Enzyme 2 / genetics; Animals; COVID-19 / epidemiology; COVID-19 / veterinary; Lemur / genetics; Lorisidae / genetics; Primate Diseases / epidemiology; Primate Diseases / virology; Risk Factors
TL;DR:
This study reinforces previous results while finding additional variability in other strepsirrhine species, and suggests several clades of lemurs have high potential susceptibility to SARS‐CoV‐2 infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: April 19, 2021
2020 review
Rhesus macaques as a tractable physiological model of human ageing
author keywords: geroscience; immunosenescence; gene regulation; primate; Cayo Santiago
MeSH headings : Aging; Animals; Gene Regulatory Networks / immunology; Humans; Immune System / metabolism; Macaca mulatta / physiology; Models, Animal
TL;DR:
It is anticipated that continuing research in rhesus macaques and other nonhuman primates will play a critical role in conjunction with model organism and human biodemographic research in ultimately improving translational outcomes and extending health and longevity in the authors' ageing population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: October 26, 2020
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