2013 article

Optimizing the simultaneous management of blood pressure and cholesterol for type 2 diabetes patients

Mason, J. E., Denton, B. T., Shah, N. D., & Smith, S. A. (2013, September 25). European Journal of Operational Research.

By: J. Mason n, B. Denton n, N. Shah* & S. Smith*

author keywords: OR in medicine; Markov decision process; Type 2 diabetes; Blood pressure treatment; Cholesterol treatment
topics (OpenAlex): Health Systems, Economic Evaluations, Quality of Life; Blood Pressure and Hypertension Studies; Lipoproteins and Cardiovascular Health
TL;DR: A Markov decision process (MDP) model is presented to determine the optimal timing of blood pressure and cholesterol medications for patients with type 2 diabetes and the trade off between quality-adjusted life years and costs of treatment. (via Semantic Scholar)
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2012 article

A comparison of decision-maker perspectives for optimal cholesterol treatment

Mason, J. E., & Denton, B. T. (2012, August 7). IBM Journal of Research and Development.

By: J. Mason n & B. Denton n

topics (OpenAlex): Health Systems, Economic Evaluations, Quality of Life; Pharmaceutical Economics and Policy; Advanced Causal Inference Techniques
TL;DR: A Markov decision process (MDP) is used to show how decision-maker perspectives can influence medical treatment decisions related to cardiovascular risk management in patients with type 2 diabetes, and an inverse MDP model is formulated to estimate the implied monetary value of a year of life, from the societal perspective, according to current U.S. treatment guidelines. (via Semantic Scholar)
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2011 article

Optimizing Statin Treatment Decisions for Diabetes Patients in the Presence of Uncertain Future Adherence

Mason, J. E., England, D. A., Denton, B. T., Smith, S. A., Kurt, M., & Shah, N. D. (2011, April 29). Medical Decision Making.

By: J. Mason n, D. England n, B. Denton, S. Smith n, M. Kurt n & N. Shah n

author keywords: adherence; diabetes; statins; Markov decision process
MeSH headings : Adult; Decision Making; Diabetes Mellitus, Type 2 / drug therapy; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use; Male; Markov Chains; Middle Aged; Patient Compliance; Quality-Adjusted Life Years
topics (OpenAlex): Medication Adherence and Compliance; Pharmaceutical Economics and Policy; Health Systems, Economic Evaluations, Quality of Life
TL;DR: A Markov decision process (MDP) model is used to optimize the treatment decision for patients with type 2 diabetes and determines the optimal time of statin initiation that minimizes expected costs and maximizes expected quality-adjusted life years (QALYs). (via Semantic Scholar)
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